Genetic variants in one-carbon metabolism-related genes contribute to NSCLC prognosis in a Chinese population.

abstract：BACKGROUND:Genomic testing is increasingly performed in oncology, but concerns remain regarding the clinician's ability to interpret results. In the current study, the authors sought to determine the agreement between physicians and genomic annotators from the Precision Oncology Decision Support (PODS) team at The Univ...

journal_title：Cancer

authors： Brusco LL,Wathoo C,Mills Shaw KR,Holla VR,Bailey AM,Johnson AM,Khotskaya YB,Litzenburger BC,Sanchez NS,Zeng J,Bernstam EV,Eng C,Kee BK,Amaria RN,Routbort MJ,Mills GB,Mendelsohn J,Meric-Bernstam F

更新日期：2018-03-01 00:00:00

abstract：:A case of malignant eccrine poroma with lymph node metastases is described. The patient had a nodular growth of the right thigh 2 years before its first excision. Local recurrence in the scar occurred in 6 months, and by 8 months a right groin lymph node was involved. Subsequent skin nodules of the right thigh occurre...

journal_title：Cancer

authors： Bottles K,Sagebiel RW,McNutt NS,Jensen B,Deveney K

更新日期：1984-04-01 00:00:00

abstract：BACKGROUND:To identify potential genetic markers for severe oxaliplatin-induced chronic peripheral neuropathy (OXCPN), the authors performed a genome-wide association analysis of patients with colon cancer who received oxaliplatin-based chemotherapy. METHODS:This was a prospective study in which DNA was purified in pe...

journal_title：Cancer

authors： Won HH,Lee J,Park JO,Park YS,Lim HY,Kang WK,Kim JW,Lee SY,Park SH

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:The identification of the BRCA1 gene is a powerful tool for predicting a patient's lifetime risk for carcinoma of the breast and ovary when she has hereditary breast/ovarian carcinoma (HBOC) syndrome. The process of BRCA1 testing and genetic counseling and participants' reactions to test results, are describ...

journal_title：Cancer

authors： Lynch HT,Lemon SJ,Durham C,Tinley ST,Connolly C,Lynch JF,Surdam J,Orinion E,Slominski-Caster S,Watson P,Lerman C,Tonin P,Lenoir G,Serova O,Narod S

更新日期：1997-06-01 00:00:00

abstract：:To optimize the prognostic value of DNA flow cytometry in breast cancer the authors calculated several parameters from the DNA histogram, including the DNA index, the size and number of aneuploid peaks as well as S-phase and G2/M-phase cell cycle fractions. Of these, DNA index and S-phase fraction (SPF) proved to be t...

journal_title：Cancer

authors： Kallioniemi OP,Blanco G,Alavaikko M,Hietanen T,Mattila J,Lauslahti K,Lehtinen M,Koivula T

更新日期：1988-11-15 00:00:00

abstract：BACKGROUND:Among patients with core-needle biopsy (CNB)-diagnosed ductal carcinoma in situ (DCIS), the guidelines for the selection of patients to undergo sentinel lymph node (SLN) biopsy are not well defined, and many patients with no invasion undergo an unnecessary SLN biopsy. The objective of this study was to ident...

journal_title：Cancer

authors： Huo L,Sneige N,Hunt KK,Albarracin CT,Lopez A,Resetkova E

更新日期：2006-10-15 00:00:00

abstract：BACKGROUND:The association between hormone replacement therapy (HRT) and a reduced lung cancer risk has been reported in previous studies. There is a high female to male ratio in Chinese lung cancer patients, and female patients have different clinicopathological characteristics compared with Western patient population...

journal_title：Cancer

authors： Chen KY,Hsiao CF,Chang GC,Tsai YH,Su WC,Perng RP,Huang MS,Hsiung CA,Chen CJ,Yang PC,GEFLAC Study Group.

更新日期：2007-10-15 00:00:00

abstract：BACKGROUND:The treatment of advanced, inoperable, or recurrent parotid tumors represents a clinical challenge. The results obtained with conventional radiotherapy are disappointing. To improve the early response and local control of parotid tumors, local microwave hyperthermia was used in combination with ionizing radi...

journal_title：Cancer

authors： Gabriele P,Amichetti M,Orecchia R,Valdagni R

更新日期：1995-02-15 00:00:00

abstract：BACKGROUND:High-dose methotrexate (MTX) is an important component of current protocols for the treatment of osteosarcoma. Although MTX uptake proceeds primarily through the reduced folate carrier (RFC) protein and efflux occurs via multidrug resistance protein 1 (MRP1), RFC protein expression in osteosarcoma remains un...

journal_title：Cancer

authors： Ifergan I,Meller I,Issakov J,Assaraf YG

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:To the authors' knowledge, little is known to date regarding the prognostic relevance of measuring serum levels of vascular endothelial growth factor (VEGF), a potent stimulator of angiogenesis, in patients with colon carcinoma who undergo surgery. METHODS:Preoperative and postoperative VEGF serum levels we...

journal_title：Cancer

authors： De Vita F,Orditura M,Lieto E,Infusino S,Morgillo F,Martinelli E,Castellano P,Romano C,Ciardiello F,Catalano G,Pignatelli C,Galizia G

更新日期：2004-01-15 00:00:00

abstract：BACKGROUND:To clarify the differences in angiogenesis between benign and malignant ovarian tumors, the authors examined the immunohistochemical characteristics and the density of tumor vessels in both tumor groups. Intratumoral vascularization was observed preoperatively by transvaginal color Doppler ultrasound. METHO...

journal_title：Cancer

authors： Emoto M,Iwasaki H,Mimura K,Kawarabayashi T,Kikuchi M

更新日期：1997-09-01 00:00:00

abstract：BACKGROUND:Adult "translocation" renal cell carcinoma (RCC), bearing transcription factor E3 (TFE3) gene fusions at Xp11.2, is a recently recognized, unique entity for which prognosis and therapy remain poorly understood. In the current study, the authors investigated the effect of vascular endothelial growth factor (V...

journal_title：Cancer

authors： Choueiri TK,Lim ZD,Hirsch MS,Tamboli P,Jonasch E,McDermott DF,Dal Cin P,Corn P,Vaishampayan U,Heng DY,Tannir NM

更新日期：2010-11-15 00:00:00

abstract：BACKGROUND:The role of resectional surgery in patients with advanced stages of gallbladder carcinoma has not been fully defined. It is generally believed that the survival depends on the stage of the disease, rather than on the treatment option. METHODS:Seventeen selected risk factors were analyzed using univariate an...

journal_title：Cancer

authors： Pradeep R,Kaushik SP,Sikora SS,Bhattacharya BN,Pandey CM,Kapoor VK

更新日期：1995-10-01 00:00:00

abstract：BACKGROUND:Smoldering multiple myeloma (SMM) presents a high risk of progression to symptomatic MM (sy-MM). Herein, we analyzed some predictors of development of sy-MM. In 144 patients with SMM, we also compared the risk of progression predicted by bone marrow plasma cell (BMPC) involvement on the bone marrow biopsy (B...

journal_title：Cancer

authors： Rago A,Grammatico S,Za T,Levi A,Mecarocci S,Siniscalchi A,De Rosa L,Felici S,Bongarzoni V,Piccioni AL,La Verde G,Pisani F,Franceschini L,Paviglianiti AL,Caravita T,Petrucci MT,De Stefano V,Cimino G,Multiple Myeloma GI

更新日期：2012-11-15 00:00:00

abstract：:Small-cell lung cancer (SCLC) represents 15% to 20% of all lung carcinomas. Approximately 30% to 40% of these cases are diagnosed in patients older than 70 years of age. Staging of SCLC classifies patients as having either limited or extensive-stage disease. The standard treatment for limited-stage disease is platinum...

journal_title：Cancer

authors： Pallis AG,Shepherd FA,Lacombe D,Gridelli C

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:Adequate prediction of survival is important in deciding on treatment for patients with symptomatic spinal metastases. The authors reviewed 342 patients with painful spinal metastases without neurologic impairment who were treated conservatively within a large, prospectively randomized radiotherapy trial. Re...

journal_title：Cancer

authors： van der Linden YM,Dijkstra SP,Vonk EJ,Marijnen CA,Leer JW,Dutch Bone Metastasis Study Group.

更新日期：2005-01-15 00:00:00

abstract：:The first three well-documented cases of pure, extraskeletal telangiectatic osteosarcoma of the soft tissues are presented in this article. The distinctive gross features were a predominance of large, blood-filled spaces, which, on histologic examination, were large blood-filled cavities in association with cyst-like ...

journal_title：Cancer

authors： Mirra JM,Fain JS,Ward WG,Eckardt JJ,Eilber F,Rosen G

更新日期：1993-05-15 00:00:00

abstract：BACKGROUND:Rural residence has been associated with increased risk of late stage cancer diagnosis, but it is unknown if this is related to lower socioeconomic status (SES) of rural residents or to other factors. This study examined the impacts of SES and urban/rural status on colorectal cancer (CRC) stage at diagnosis ...

journal_title：Cancer

authors： Parikh-Patel A,Bates JH,Campleman S

更新日期：2006-09-01 00:00:00

abstract：:From November 1973 to May 1986, 50 patients with Stage I epithelial ovarian cancer were treated at the University of Kentucky Medical Center (Lexington, KY) with oral Alkeran (melphalan) chemotherapy after primary surgery. Twenty-two patients had Grade 1 tumors, 23 patients had Grade 2 tumors, and five patients had Gr...

journal_title：Cancer

authors： Gallion HH,van Nagell JR,Donaldson ES,Higgins RV,Powell DE,Kryscio RJ

更新日期：1989-03-15 00:00:00

abstract：BACKGROUND:Allogeneic hematopoietic cell transplantation (HCT) is a curative therapy for patients with acute myeloid leukemia (AML). However, post-HCT relapse and regimen-related toxicity remain significant barriers to long-term survival. In recent years, new conditioning regimens have been explored to improve transpla...

journal_title：Cancer

authors： Nagler A,Labopin M,Beelen D,Ciceri F,Volin L,Shimoni A,Foá R,Milpied N,Peccatori J,Polge E,Mailhol A,Mohty M,Savani BN

更新日期：2017-07-15 00:00:00

abstract：BACKGROUND:Radiation recall is a recurrence of acute toxicity within a previously quiescent radiation field that occurs with subsequent administration of chemotherapy. METHODS:A patient with acquired immune deficiency syndrome (AIDS)-related Kaposi sarcoma (KS) who had radiation recall is reported. The patient was par...

journal_title：Cancer

authors： Stelzer KJ,Griffin TW,Koh WJ

更新日期：1993-02-15 00:00:00

abstract：:The relationships between cigarette smoking, occupational exposures, dietary vitamin A and lung cancer is explored in a case-control study. The study is based on 1002 primary lung cancers among white men and 1119 white male controls between 35 and 79 years of age admitted to Roswell Park Memorial Institute from 1957 t...

journal_title：Cancer

authors： Vena JE,Byers TE,Cookfair D,Swanson M

更新日期：1985-08-15 00:00:00

abstract：:The kinetic perturbations induced by vincristine, cyclophosphamide, and adriamycin were studied in the bone marrow of a patient with neuroblastoma. Serial marrow samples were studied by dual parameter (Coulter volume and DNA content), flow cytometry, and radioautography, and findings were correlated with cytomorpholog...

journal_title：Cancer

authors： Shackney SE,Bunn PA,Ford SS,Erickson B,Ross WE,Levine AS

更新日期：1980-03-01 00:00:00

abstract：:Cancer tissues from 30 patients with squamous cell carcinoma of the oral cavity were examined immunohistopathologically as to the responsiveness of the host against its own cancer cells in both biopsy and surgically resected specimens from the same patients. Subpopulations of the infiltrating lymphocytes in cancer tis...

journal_title：Cancer

authors： Hiratsuka H,Imamura M,Ishii Y,Kohama G,Kikuchi K

更新日期：1984-06-01 00:00:00

abstract：BACKGROUND:The aim of this work was to study the expression of alpha, beta1, and beta4 integrin subunits in meningiomas. METHODS:Seventeen atypical or anaplastic meningiomas were retrieved from the files of Hôpital de Bellevue, Saint-Etienne, France. They were compared with 17 benign meningiomas consecutively examined...

journal_title：Cancer

authors： Beschet I,Brunon J,Scoazec JY,Mosnier JF

更新日期：1999-12-15 00:00:00

abstract：:Experience with high-dose cytosine arabinoside (HDAC) in pediatric solid tumors is limited. Sixteen children with solid tumors resistant to conventional therapies were registered in a pilot Pediatric Oncology Group (POG) study that required the administration of HDAC at 3 g/m2 every 12 hours for four doses. There were...

journal_title：Cancer

authors： Tebbi CK,Krischer J,Fernbach DJ,Mahoney DH,Alvarado C,Camitta B

更新日期：1990-11-15 00:00:00

abstract：BACKGROUND:There is significant need for quality follow-up care to optimize long-term outcomes for the growing population of lower gastrointestinal (GI) cancer survivors. Patient-reported outcomes (PROs) provide valuable information regarding late and long-term effects (LLTEs). METHODS:A convenience sample from 1129 c...

journal_title：Cancer

authors： Frick MA,Vachani CC,Hampshire MK,Bach C,Arnold-Korzeniowski K,Metz JM,Hill-Kayser CE

更新日期：2017-05-15 00:00:00

abstract：BACKGROUND:4'-0-tetrahydropyranyladriamycin (Pirarubicin, Meiji Seika (USA) Inc., New York, NY) may be less toxic than doxorubicin. METHODS:A Phase II trial of Pirarubicin was done in 26 patients who had not previously had chemotherapy and who had measurable and incurable head and neck carcinoma. All patients received...

journal_title：Cancer

authors： Sridhar KS,Hussein AM,Benedetto P,Ardalan B,Savaraj N,Richman SP

更新日期：1992-09-15 00:00:00

abstract：BACKGROUND:Cisplatin has been reported to enhance the cell-killing effect of radiation. The current study was conducted to evaluate the efficacy and toxicity of radiotherapy combined with cisplatin in patients with locally advanced pancreatic carcinoma. METHODS:Forty-one patients with pancreatic carcinoma that was unr...

journal_title：Cancer

authors： Okusaka T,Okada S,Tokuuye K,Wakasugi H,Saisho H,Ishikawa O,Matsuno S,Sato T,Sato K,Non-surgical Treatment Group for Pancreatic Cancer in Japan.

更新日期：2001-04-01 00:00:00

abstract：BACKGROUND:Neuroblastoma is the most common malignancy among infants, but risk factors remain poorly understood. Because most patients present in the first few years of life, it has been hypothesized that prenatal and perinatal exposures may contribute to the pathogenesis of neuroblastoma. METHODS:A population-based c...

journal_title：Cancer

authors： Chow EJ,Friedman DL,Mueller BA

更新日期：2007-03-01 00:00:00