Treatment of small-cell lung cancer in elderly patients.

abstract：BACKGROUND:The reliability of cytologic criteria to classify nonproliferative breast lesions (NPBL) is still debated. Sampling error and heterogeneity of breast lesions complicates the histologic correlation of fine-needle aspiration results further. METHODS:To provide optimal cytohistologic correlation, two smears (o...

journal_title：Cancer

authors： Sidawy MK,Tabbara SO,Bryan JA,Poprocky LA,Frost AR

更新日期：2001-04-25 00:00:00

abstract：BACKGROUND:The incidence of adenocarcinoma of the cervix did not decline in Western countries in the 1970s and 1980s despite the availability and use of cervical cytologic screening. The impact of improved endocervical sampling and better recognition of the cytologic precursors to adenocarcinoma during the 1990s in red...

journal_title：Cancer

authors： Mitchell H,Hocking J,Saville M

更新日期：2003-12-25 00:00:00

abstract：BACKGROUND:The severity of myelotoxicity after radioimmunotherapy has been predicted from body and blood radiation doses to marrow. However, marrow radiation can be increased substantially if the marrow or skeleton contains the malignancy targeted by the radiolabeled monoclonal antibodies. A study of 29 patients treate...

journal_title：Cancer

authors： DeNardo DA,DeNardo GL,O'Donnell RT,Lim SM,Shen S,Yuan A,DeNardo SJ

更新日期：1997-12-15 00:00:00

abstract：BACKGROUND:Children with acute lymphoblastic leukemia with multiple poor prognostic factors and who have a lymphomatous mass at diagnosis, whether of T- or non-T-immunophenotype, are at increased risk of short term remission and extramedullary recurrence, and are in need of better therapies. METHODS:Six hundred and ni...

journal_title：Cancer

authors： Steinherz PG,Gaynon PS,Breneman JC,Cherlow JM,Grossman NJ,Kersey JH,Johnstone HS,Sather HN,Trigg ME,Uckun FM,Bleyer WA

更新日期：1998-02-01 00:00:00

abstract：BACKGROUND:The p53 tumor suppressor gene encodes a nuclear phosphoprotein that is thought to be important to cell cycle regulation and DNA repair and that also may regulate induction of apoptosis by ionizing radiation. Somatic p53 gene mutations occur in 30-50% of breast carcinomas and are associated with poor prognosi...

journal_title：Cancer

authors： Turner BC,Gumbs AA,Carbone CJ,Carter D,Glazer PM,Haffty BG

更新日期：2000-03-01 00:00:00

abstract：:In order to determine whether the use of a sequence of chemotherapeutic regimens plus BCG could produce longer durations of remission in adult acute nonlymphocytic leukemia than maintenance therapy with cytosine arabinoside, 6-thioguanine, plus BCG, a randomized study was performed at Washington University. Upon achie...

journal_title：Cancer

authors： Presant CA,Berger NA,Klahr C,Phillips GL

更新日期：1980-07-01 00:00:00

abstract：:Breast fluid was collected from 244 nonlactating Finnish women with no known breast disease and analyzed with respect to various epidemiologic and hormonal parameters commonly associated with breast cancer risk. The data obtained permit characterization of women with breast secretory ability and provide fundamental in...

journal_title：Cancer

authors： Wynder EL,Hill P,Laakso K,Littner R,Kettunen K

更新日期：1981-03-15 00:00:00

abstract：BACKGROUND:Posttransplant lymphoproliferative disorder (PTLD) is a life-threatening complication of solid organ transplantation. Histologic heterogeneity and a lack of treatment standards have made evaluating clinical outcomes in specific patient populations difficult. This systematic literature review investigated the...

journal_title：Cancer

authors： Koff JL,Li JX,Zhang X,Switchenko JM,Flowers CR,Waller EK

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Poor prognosis of Stage IV breast cancer patients have at best a 10% 3-year survival rate with conventional chemotherapy. Dose-intensive chemotherapy improved survival rates for some of these patients. METHODS:All patients were Stage IV estrogen receptor-negative or estrogen receptor-positive hormonal refra...

journal_title：Cancer

authors： Dunphy FR,Spitzer G,Fornoff JE,Yau JC,Huan SD,Dicke KA,Buzdar AU,Hortobagyi GN

更新日期：1994-04-15 00:00:00

abstract：:Many investigators have regarded Stage III lymphomas as a generalized form of disease and have accordingly recommended systemic treatment programs. Between 1961 and 1973, 68 patients with clinical or pathologic Stage III non-Hodgkin's lymphomas were seen in the Division of Radiation Therapy at Stanford University Medi...

journal_title：Cancer

authors： Glatstein E,Fuks Z,Goffinet DR,Kaplan HS

更新日期：1976-06-01 00:00:00

abstract：:Retinitis pigmentosa, a hereditary disease characterized by progressive retinal degeneration and blindness, has been associated with numerous diseases. We report the first association between retinitis pigmentosa and colon cancer in 3 of 53 hospitalized patients with retinitis pigmentosa at the Massachusetts General H...

journal_title：Cancer

authors： Winzelberg GG,Greenstein R,Ferrucci JT Jr

更新日期：1980-06-01 00:00:00

abstract：BACKGROUND:Men who receive androgen-deprivation therapy (ADT) for prostate cancer experience several side effects from this treatment. A few recent studies have examined the cognitive implications of ADT and how they impact a patient's treatment decision-making, occupational pursuits, and quality of life. For this repo...

journal_title：Cancer

authors： Nelson CJ,Lee JS,Gamboa MC,Roth AJ

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:Genomic testing is increasingly performed in oncology, but concerns remain regarding the clinician's ability to interpret results. In the current study, the authors sought to determine the agreement between physicians and genomic annotators from the Precision Oncology Decision Support (PODS) team at The Univ...

journal_title：Cancer

authors： Brusco LL,Wathoo C,Mills Shaw KR,Holla VR,Bailey AM,Johnson AM,Khotskaya YB,Litzenburger BC,Sanchez NS,Zeng J,Bernstam EV,Eng C,Kee BK,Amaria RN,Routbort MJ,Mills GB,Mendelsohn J,Meric-Bernstam F

更新日期：2018-03-01 00:00:00

abstract：:Responding to growing concerns regarding the safety, quality, and efficacy of cancer care in the United States, the Institute of Medicine (IOM) of the National Academy of Sciences commissioned a comprehensive review of cancer care delivery in the US health care system in the late 1990s. The National Cancer Policy Boar...

journal_title：Cancer

authors： Spinks T,Albright HW,Feeley TW,Walters R,Burke TW,Aloia T,Bruera E,Buzdar A,Foxhall L,Hui D,Summers B,Rodriguez A,Dubois R,Shine KI

更新日期：2012-05-15 00:00:00

abstract：BACKGROUND:An association between laryngopharyngeal reflux (LPR) and laryngeal carcinoma has been suggested, but remains unproven. The current pilot study was performed to determine the incidence of LPR among patients with early laryngeal carcinomas or dysplasia and to examine the associations between levels of LPR and...

journal_title：Cancer

authors： Lewin JS,Gillenwater AM,Garrett JD,Bishop-Leone JK,Nguyen DD,Callender DL,Ayers GD,Myers JN

更新日期：2003-02-15 00:00:00

abstract：:Nickel-related cancers of the respiratory tract have been recognized for nearly 50 years and represent a unique opportunity for prevention among refinery workers. Studies of exposed employees have been conducted in which evaluations were made of the histopathologic changes in the respiratory mucosa and the body burden...

journal_title：Cancer

authors： Barton RT,Hogetveit AC

更新日期：1980-06-15 00:00:00

abstract：:Two published cases of medulloepithelioma, a rare malignant pediatric brain tumor composed of a mixture of primitive neuroepithelium and its differentiated neuronal and glial descendants, were examined by immunohistochemical staining for the presence of growth factors. From a panel of antibodies, those identifying bas...

journal_title：Cancer

authors： Shiurba RA,Buffinger NS,Spencer EM,Urich H

更新日期：1991-08-15 00:00:00

abstract：BACKGROUND:Disruption of the lymphatic circulation through breast carcinoma-associated axillary lymph node dissection, with or without radiation therapy, reportedly is the most common cause of lymphedema in developed countries. There is no cure for breast carcinoma-associated lymphedema. Although intermittent pneumatic...

journal_title：Cancer

authors： Szuba A,Achalu R,Rockson SG

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND:The sensitivity of the intraoperative diagnosis of sentinel lymph node (SLN) micrometastases and the metastases of invasive lobular carcinoma (ILC) is low. The goal of the current study was to assess whether the use of intraoperative, rapid immunohistochistochemistry (IHC) enhances the intraoperative detecti...

journal_title：Cancer

authors： Leikola JP,Toivonen TS,Krogerus LA,von Smitten KA,Leidenius MH

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND:The objective of this study was to create a nomogram model integrating clinical and multiparametric magnetic resonance imaging (MP-MRI)-based variables to predict prostate cancer upgrading in a population of active surveillance (AS) patients. METHODS:Prostate cancer patients on AS who underwent MP-MRI with ...

journal_title：Cancer

authors： Lai WS,Gordetsky JB,Thomas JV,Nix JW,Rais-Bahrami S

更新日期：2017-06-01 00:00:00

abstract：:Over an 18-year period a distinctive large cell lymphoreticular neoplasm (Richter's transformation) developed in 9 patients with chronic lymphocytic leukemia. Clinical findings at the onset of Richter's transformation were remarkably uniform and consisted of the abrupt onset of fever, marked asymmetric lymphadenopathy...

journal_title：Cancer

authors： Foucar K,Rydell RE

更新日期：1980-07-01 00:00:00

abstract：BACKGROUND:More cases of bronchogenic carcinoma have been reported in recent years, and these patients are more prone to secondary aspergillosis. However, the frequency of secondary aspergillosis in bronchogenic carcinoma still has not been defined clearly in the literature. METHODS:The current study population was co...

journal_title：Cancer

authors： Shahid M,Malik A,Bhargava R

更新日期：2008-08-01 00:00:00

abstract：:The serum lactase dehydrogenase (LDH) of 56 patients with Ewing's sarcoma was examined to determine the use of LDH as a tumor marker. The initial LDH level was used to determine its ability to predict survival. The follow-up LDH level also was examined, as an indicator of recurrent disease. The initial LDH level was f...

journal_title：Cancer

authors： Farley FA,Healey JH,Caparros-Sison B,Godbold J,Lane JM,Glasser DB

更新日期：1987-04-01 00:00:00

abstract：:The histologic features of a malignant clear cell acrospiroma were those of infiltrative local growth, frequent mitoses and angiolymphatic invasion. The histochemical and ultrastructural findings were similar to those reported for benign clear cell acrospriomas. Amputation of the leg and regional node dissection were ...

journal_title：Cancer

authors： Headington JT,Niederhuber JE,Beals TF

更新日期：1978-02-01 00:00:00

abstract：:Tumor necrosis factor-alpha (TNF-alpha), a product of activated macrophages that is cytotoxic to tumor cells, could be used to purge tumor cells from bone marrow before autologous bone marrow transplantation for hematologic malignancies and/or solid tumors. To determine whether exposure to TNF-alpha would have an inhi...

journal_title：Cancer

authors： Abboud SL,Gerson SL,Berger NA

更新日期：1987-12-15 00:00:00

abstract：BACKGROUND:Among the several proposed risk classification schemes for predicting survival in women with breast carcinoma, one of the most commonly used is the Nottingham Prognostic Index (NPI). The goal of the current study was to use a continuous prognostic model (similar to those that have already been demonstrated t...

journal_title：Cancer

authors： Kattan MW,Giri D,Panageas KS,Hummer A,Cranor M,Van Zee KJ,Hudis CA,Norton L,Borgen PI,Tan LK

更新日期：2004-12-01 00:00:00

abstract：:Twenty of 391 newly diagnosed cases of prostatic cancer (5%) had a prior prostatectomy for benign disease. Digital rectal examination in 16 of 19 patients (84%) revealed a significant prostatic abnormality. Continued serial digital rectal examination should be performed routinely after prostatectomy for benign disease...

journal_title：Cancer

authors： Schwartz I,Wein AJ,Malloy TR,Glick JH

更新日期：1986-08-15 00:00:00

abstract：:One hundred twenty-three women younger than 70 years of age and at clinical Stages I or II were enrolled in a randomized clinical trial of radical versus extended radical mastectomy. The 5-year survival rates in the radical and extended radical groups were 75 +/- 6.7% and 80 +/- 6.7%, respectively. (Cox P value for co...

journal_title：Cancer

authors： Meier P,Ferguson DJ,Karrison T

更新日期：1985-02-15 00:00:00

abstract：BACKGROUND:Hepatocellular carcinoma (HCC) with portal venous invasion (PVI) has a very poor prognosis, with a median survival of 3 months and virtually no survival at 1 year. The combination of intraarterial 5-fluorouracil (FU) and systemic interferon-alpha (IFNalpha) was recently reported to be effective against HCC w...

journal_title：Cancer

authors： Obi S,Yoshida H,Toune R,Unuma T,Kanda M,Sato S,Tateishi R,Teratani T,Shiina S,Omata M

更新日期：2006-05-01 00:00:00

abstract：:The American Joint Committee on Cancer proposes the following criteria for evaluating putative prognostic factors: they must be (1) significant, (2) independent, and (3) clinically important. Furthermore, we suggest the criteria for selecting a prognostic system that includes TNM and new prognostic factors. These crit...

journal_title：Cancer

authors： Burke HB,Henson DE

更新日期：1993-11-15 00:00:00