Non-Hodgkin's lymphomas of stage III extent. Is total lymphoid irradiation appropriate treatment?

abstract：:To additionally understand the molecular mechanisms and biologic indicators of colonic tumorigenesis through the adenoma-carcinoma sequence, protein kinase C (PKC) activity was examined in the cytosol and particulate fraction of specimen homogenates from 18 human colonic carcinomas and seven coexisting colonic adenoma...

journal_title：Cancer

authors： Kusunoki M,Sakanoue Y,Hatada T,Yanagi H,Yamamura T,Utsunomiya J

更新日期：1992-01-01 00:00:00

abstract：:Eighty-one female patients with phyllodes tumors of the breast, surgically treated from 1974 to 1983, were studied. Their age ranged from 9 to 88 years. According to histology, the series was divided into three groups, of 28 (34.5%) benign tumors, 32 (39.5%) border-line tumors, and 21 (25.9%) malignant tumors. Because...

journal_title：Cancer

authors： Salvadori B,Cusumano F,Del Bo R,Delledonne V,Grassi M,Rovini D,Saccozzi R,Andreola S,Clemente C

更新日期：1989-06-15 00:00:00

abstract：:Spindle cell lipoma is a specific type of lipoma that is easily mistaken for a liposarcoma. An analysis of 114 cases of this tumor from the files of the Armed Forces Institute of Pathology reveals that is occurs chiefly in male patients between 45 and 70 years of age and affects the regions of the shoulder and posteri...

journal_title：Cancer

authors： Enzinger FM,Harvey DA

更新日期：1975-11-01 00:00:00

abstract：BACKGROUND:This study analyzed whether proliferative activity and expression of P-glycoprotein 170 (P-170) or glutathione S-transferase-pi (GST-pi) in human non-small cell lung carcinomas (NSCLC) represent independent factors in resistance to doxorubicin or whether an association exists between these factors. METHODS:...

journal_title：Cancer

authors： Volm M,Mattern J,Samsel B

更新日期：1992-08-15 00:00:00

abstract：:The authors studied the expression of c-myc and ras family oncogene products in 43 cases of malignant lymphoma (ML) using the immunoperoxidase method. Unfixed frozen sections of lymph nodes from four patients with Hodgkin's disease and 39 with non-Hodgkin's lymphoma, together with normal lymph nodes, were studied by t...

journal_title：Cancer

authors： Mitani S,Sugawara I,Shiku H,Mori S

更新日期：1988-11-15 00:00:00

abstract：BACKGROUND:To evaluate the pathologic characteristics of the primary tumor relative to local control, survival, and freedom from distant metastases, an analysis was performed of 172 patients with ductal carcinoma in situ (intraductal carcinoma) of the breast treated with breast-conserving surgery and definitive breast ...

journal_title：Cancer

authors： Solin LJ,Yeh IT,Kurtz J,Fourquet A,Recht A,Kuske R,McCormick B,Cross MA,Schultz DJ,Amalric R

更新日期：1993-04-15 00:00:00

abstract：BACKGROUND:Expression of neuroectodermal markers is a key feature of small cell lung carcinoma (SCLC). Although immune responses against a number of these proteins have been associated with paraneoplastic neuronal disease (PND), most patients with SCLC have anti-neuroectodermal antibodies in the absence of PND. Whether...

journal_title：Cancer

authors： Vural B,Chen LC,Saip P,Chen YT,Ustuner Z,Gonen M,Simpson AJ,Old LJ,Ozbek U,Gure AO

更新日期：2005-06-15 00:00:00

abstract：BACKGROUND:Men who undergo radical prostatectomy (RP) are at long-term risk of biochemical recurrence (BCR). In this report, the authors have described a model capable of predicting BCR up to at least 15 years after RP that can adjust predictions according to the disease-free interval. METHODS:Cox regression was used ...

journal_title：Cancer

authors： Suardi N,Porter CR,Reuther AM,Walz J,Kodama K,Gibbons RP,Correa R,Montorsi F,Graefen M,Huland H,Klein EA,Karakiewicz PI

更新日期：2008-03-15 00:00:00

abstract：:Twenty-one cases of clear cell adenocarcinoma of the cervix and vagina have been reviewed. Fifteen cases occurred in females under 25 years of age and four in women over 45 years. In seven cases, a positive history of maternal ingestion of diethylstilbestrol (DES) was obtained. One mother gave a history of medication ...

journal_title：Cancer

authors： Nordqvist SR,Fidler WJ Jr,Woodruff JM,Lewis JL Jr

更新日期：1976-02-01 00:00:00

abstract：:To determine the quality of survival for children with posterior fossa tumors, comprehensive neuropsychological, behavioral, and academic assessment and physician ratings of functional status were obtained on 15 brain tumor patients (ages 6-19 years) at a median of 20 months post-diagnosis. More than 50% of the childr...

journal_title：Cancer

authors： LeBaron S,Zeltzer PM,Zeltzer LK,Scott SE,Marlin AE

更新日期：1988-09-15 00:00:00

abstract：:Twelve cases of ovarian adenocarcinoma were studied for alterations in proto-oncogenes, and a unique pattern of altered ras proto-oncogenes was observed. Amplification of ras-Ki was found in three of seven ovarian tumors and amplification of ras-Ha in one of 12. In contrast, ras-Ha amplification was not found in any o...

journal_title：Cancer

authors： Zhou DJ,Gonzalez-Cadavid N,Ahuja H,Battifora H,Moore GE,Cline MJ

更新日期：1988-10-15 00:00:00

abstract：BACKGROUND:The development of new chelating agents and radiolabeling protocols is essential to progress in radioimmunotherapy with antibody-chelate conjugates. METHODS:Immunoconjugates of four polyazamacrocycles with N-bonded acetate groups were prepared by conjugation via 2-iminothiolane to Lym-1, a murine antilympho...

journal_title：Cancer

authors： Kukis DL,Diril H,Greiner DP,DeNardo SJ,DeNardo GL,Salako QA,Meares CF

更新日期：1994-02-01 00:00:00

abstract：:Some variant of mastectomy remains the mainstay of the treatment of the primary tumor for the vast majority of the 110,000 new cases of cancer of the breast which will be treated this year in the United States. Reconstruction of the breast after ablation for cancer has become an integral part of the therapeutic regime...

journal_title：Cancer

authors： Dinner MI,Dowden RV

更新日期：1984-02-01 00:00:00

abstract：:The authors report four patients whose initial symptom of tumor recurrence or progression was unilateral numbness of the chin. Two patients had Hodgkin lymphoma, one had malignant melanoma, and one had prostate cancer. Physical examination was notable only for unilateral anesthesia of the chin and lower lip. Diagnosti...

journal_title：Cancer

authors： Burt RK,Sharfman WH,Karp BI,Wilson WH

更新日期：1992-08-15 00:00:00

abstract：BACKGROUND:Bisphosphonates currently are the most important class of antiresorptive agents used in the treatment of metabolic bone diseases, including tumor-associated osteolysis and hypercalcemia, Paget's disease, and osteoporosis. These compounds have high affinity for calcium and therefore target to bone mineral, wh...

journal_title：Cancer

authors： Rogers MJ,Gordon S,Benford HL,Coxon FP,Luckman SP,Monkkonen J,Frith JC

更新日期：2000-06-15 00:00:00

abstract：BACKGROUND:The delayed effects (12-16 hours) of transdermal fentanyl make dose titration difficult during acute exacerbations of cancer pain. Patients at the authors' institution routinely are switched from transdermal to intravenous (IV) fentanyl using a 1:1 (transdermal:IV) conversion during severe episodes of pain. ...

journal_title：Cancer

authors： Kornick CA,Santiago-Palma J,Schulman G,O'Brien PC,Weigand S,Payne R,Manfredi PL

更新日期：2003-06-15 00:00:00

abstract：:Between June 1977 and December 1978, occult testicular leukemia (OTL) was discovered at three years of continual complete remission (CCR) from the time of diagnosis of acute lymphoblastic leukemia (ALL) in 5 of 59 (8.5%) of males undergoing bilateral wedge testicular biopsy at 1 of 15 participating Southwest Oncology ...

journal_title：Cancer

authors： Askin FB,Land VJ,Sullivan MP,Ragab AH,Steuber CP,Dyment PG,Talbert J,Moore T

更新日期：1981-02-01 00:00:00

abstract：BACKGROUND:The authors recently reported on the role of cyclin E in differentiating ovarian/primary peritoneal carcinoma from malignant peritoneal mesothelioma using gene expression arrays. In the current study, they analyzed the expression of low-molecular weight (LMW) forms of cyclin E in ovarian carcinoma, malignant...

journal_title：Cancer

authors： Davidson B,Skrede M,Silins I,Shih IeM,Trope CG,Flørenes VA

更新日期：2007-09-15 00:00:00

abstract：BACKGROUND:Significant antitumor effects were previously observed with radioimmunotherapy (RIT) using an anti-carcinoembryonic antigen (CEA) monoclonal antibody (F6) labeled with iodine-131 in medullary thyroid cancer (MTC)-bearing nude mice. Nevertheless, no complete response was achieved. Because angiogenesis is crit...

journal_title：Cancer

authors： Salaun PY,Bodet-Milin C,Frampas E,Oudoux A,Saï-Maurel C,Faivre-Chauvet A,Barbet J,Paris F,Kraeber-Bodéré F

更新日期：2010-02-15 00:00:00

abstract：:Forty-one previously untreated patients with a diagnosis of acute myelogenous leukemia (AML) were entered on a study using early intensification followed by a short-term maintenance chemotherapy. Induction and early intensification consisted of three to four cycles of doxorubicin, vincristine, cytosine arabinoside (Ar...

journal_title：Cancer

authors： Kantarjian HM,Keating MJ,Walters RS,McCredie KB,Bodey GP,Freireich EJ

更新日期：1986-10-15 00:00:00

abstract：BACKGROUND:Multiple cell-signaling ligands and receptors-including vascular endothelial growth factor (VEGF), insulin-like growth factor (IGF), endothelial growth factor (EGF), v-akt murine thymoma viral oncogene homolog (AKT), platelet-derived growth factor (PDGF), mitogen-activated protein kinase (MAPK), and 70-kilod...

journal_title：Cancer

authors： Abdeen A,Chou AJ,Healey JH,Khanna C,Osborne TS,Hewitt SM,Kim M,Wang D,Moody K,Gorlick R

更新日期：2009-11-15 00:00:00

abstract：BACKGROUND:Human papillomavirus (HPV) DNA has been identified in esophageal carcinomas. However, the incidence of HPV varies significantly in different geographic locations. In the current study, neoplasms from two separate geographic regions were analyzed for the presence of HPV DNA: METHODS:One hundred and ten esoph...

journal_title：Cancer

authors： Suzuk L,Noffsinger AE,Hui YZ,Fenoglio-Preiser CM

更新日期：1996-08-15 00:00:00

abstract：:This clinicopathologic study concerns 27 cases of "dedifferentiated" soft tissue sarcoma (DSTS), including 14 liposarcomas, six leiomyosarcomas, five chondrosarcomas, and two rhabdomyosarcomas. In addition, the authors conducted an immunohistochemical survey of 23 cases and an electron microscopic examination of three...

journal_title：Cancer

authors： Hashimoto H,Daimaru Y,Tsuneyoshi M,Enjoji M

更新日期：1990-10-01 00:00:00

abstract：:A series of 27 patients with intramedullary osteogenic sarcomas that were so well-differentiated histologically as to be confused with benign lesions was studied. Of the 27 patients, 14 were females and 13 were males, and most were adults. The tibia and femur were involved commonly. Roentgenographically, the tumors sh...

journal_title：Cancer

authors： Unni KK,Dahlin DC,McLeod RA,Pritchard DJ

更新日期：1977-09-01 00:00:00

abstract：BACKGROUND:The goal of the current study was to investigate the prognostic impact of proliferative activity, together with the other classic clinicopathologic prognostic factors (tumor size, tumor grade, receptor status, ploidy, and lymph node status), in breast carcinoma by counting mitoses and evaluating S phase frac...

journal_title：Cancer

authors： Michels JJ,Marnay J,Delozier T,Denoux Y,Chasle J

更新日期：2004-02-01 00:00:00

abstract：:The continuity that exists between Hodgkin's disease and the fibrohistiocytoses has only recently been recognized. Four cases are presented that illustrate this phenomenon. The fibrohistiocytic component of the Hodgkin's lesion may lag behind the lymphoreticular component, may be present in equal proportion, or may as...

journal_title：Cancer

authors： Suster S

更新日期：1986-01-15 00:00:00

abstract：:Forty-three patients with widely metastatic melanoma were studied. Visceral metastases were present in 79% of the patient group, including five patients with brain metastases. No patients were excluded because of "early death," etc., from analysis. All 43 patients received 24-hour DTIC infusions. Dosages for individua...

journal_title：Cancer

authors： Thatcher N,Anderson H,James R,Davenport P,Craig P

更新日期：1986-06-01 00:00:00

abstract：:The possible influence of histologic grade, necrosis and size of invasive breast cancers on the five year survival rate of women treated in NSABP clinical trials with regimens of L-PAM (P) and L-PAM + 5-FU (PF) and for four years in those receiving L-PAM + 5-FU + methotrexate (PMF) was investigated. Generally, all reg...

journal_title：Cancer

authors： Fisher ER,Redmond C,Fisher B

更新日期：1983-01-15 00:00:00

abstract：BACKGROUND:Indium-111 labeled antiferritin targets 95% of all Hodgkin's disease lesions with a diameter of 1 cm or more. Subsequent treatment with yttrium-90 labeled antiferritin secures a high response rate in patients with recurrent Hodgkin's disease. METHODS:A total of 87 patients were entered on one of three diffe...

journal_title：Cancer

authors： Vriesendorp HM,Quadri SM,Andersson BS,Wyllie CT,Dicke KA

更新日期：1997-12-15 00:00:00

abstract：BACKGROUND:This retrospective study evaluated the benefit of using tumor necrosis factor (TNF) and melphalan administered via an isolated limb perfusion (ILP) in a series of patients with metastatic melanoma who failed initial ILP with chemotherapeutics. METHODS:Seventeen patients with extremity melanoma who underwent...

journal_title：Cancer

authors： Bartlett DL,Ma G,Alexander HR,Libutti SK,Fraker DL

更新日期：1997-12-01 00:00:00