Surgical treatment of phyllodes tumors of the breast.

abstract：BACKGROUND:The widespread use of anthracycline chemotherapy has contributed to improved outcomes in children with cancer. The most feared complication of the anthracyclines is cardiotoxicity. Routine echocardiographic monitoring typically is used before, during, and after treatment to minimize cardiotoxicity. The ideal...

journal_title：Cancer

authors： Watts RG,George M,Johnson WH Jr

更新日期：2012-04-01 00:00:00

abstract：:Since single drug therapy of chronic lymphocytic leukemia (CLL) has not resulted in prolonged remissions of advanced disease, we initiated a program of combination chemotherapy, COP (cycloposphamide, vincristine sulfate, prednisone) for CLL patients with increasing adenopathy, spenomegaly, and/or signs of marrow failu...

journal_title：Cancer

authors： Liepman M,Votaw ML

更新日期：1978-05-01 00:00:00

abstract：BACKGROUND:To assess whether the effectiveness of a combination of transcatheter arterial chemoembolization (TACE) and percutaneous ethanol injection (PEI) is superior to PEI alone in the treatment of patients with small hepatocellular carcinoma (HCC), a randomized controlled study was performed. METHODS:Fifty-two pat...

journal_title：Cancer

authors： Koda M,Murawaki Y,Mitsuda A,Oyama K,Okamoto K,Idobe Y,Suou T,Kawasaki H

更新日期：2001-09-15 00:00:00

abstract：BACKGROUND:The expression of a distinct alpha-3/4-monofucosylated polylactosaminoglycan epitope, which is detected by monoclonal antibody FW6, was investigated by comparative immunohistochemical analysis of colorectal tissue specimens exhibiting different grades of premalignant and malignant transformation. The presenc...

journal_title：Cancer

authors： Baldus SE,Vierbuchen M,Hanisch FG,Schwonzen M,Fischer R

更新日期：1995-09-15 00:00:00

abstract：BACKGROUND:The identification of the BRCA1 gene is a powerful tool for predicting a patient's lifetime risk for carcinoma of the breast and ovary when she has hereditary breast/ovarian carcinoma (HBOC) syndrome. The process of BRCA1 testing and genetic counseling and participants' reactions to test results, are describ...

journal_title：Cancer

authors： Lynch HT,Lemon SJ,Durham C,Tinley ST,Connolly C,Lynch JF,Surdam J,Orinion E,Slominski-Caster S,Watson P,Lerman C,Tonin P,Lenoir G,Serova O,Narod S

更新日期：1997-06-01 00:00:00

abstract：:Tumor-bearing patients with breast cancer were assayed for their natural killer (NK) cell activity and for the function of activated cytotoxic T-cells, as assessed by lectin-dependent cellular cytotoxicity (LDCC). Tumor-bearing patients with breast cancer had a significant increase in NK activity and in LDCC, as compa...

journal_title：Cancer

authors： Zielinski CC,Tichatschek E,Müller C,Kalinowski W,Sevelda P,Czerwenka K,Kubista E,Spona J

更新日期：1989-05-15 00:00:00

abstract：BACKGROUND:Race is associated with patterns of presentation and survival outcomes of gastric cancer in the United States. However, the impact of race on the receipt of guideline-recommended care is not well characterized. By using current recommendations, the authors examined the association between race and guideline-...

journal_title：Cancer

authors： Al-Refaie WB,Gay G,Virnig BA,Tseng JF,Stewart A,Vickers SM,Tuttle TM,Feig BW

更新日期：2010-01-15 00:00:00

abstract：BACKGROUND:The current study was conducted to evaluate severe mucocutaneous toxicity during treatment with hydroxyurea (HU) in a large cohort of patients with Philadelphia chromosome-negative myeloproliferative neoplasms (MPN). METHODS:Among 993 consecutive patients newly diagnosed with MPN at 4 centers in Rome betwee...

journal_title：Cancer

authors： Latagliata R,Spadea A,Cedrone M,Di Giandomenico J,De Muro M,Villivà N,Breccia M,Anaclerico B,Porrini R,Spirito F,Rago A,Avvisati G,Alimena G,Montanaro M,Andriani A,Gruppo Laziale SMPC Ph1 neg.

更新日期：2012-01-15 00:00:00

abstract：BACKGROUND:Although caspase recruitment domain (CARD) membrane-associated guanylate kinase (MAGUK) protein 1 (CARMA1) and CARD9 play important roles in lymphocyte activation, the significance of CARMA1 and CARD9 in the pathogenesis of gastric mucosa-associated lymphoid tissue (MALT) lymphoma remains to be elucidated. ...

journal_title：Cancer

authors： Nakamura S,Nakamura S,Matsumoto T,Yada S,Hirahashi M,Suekane H,Yao T,Goda K,Iida M

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND:There have been several recent reports that Wilms tumor gene (WT1) mRNA is overexpressed in many types of neoplasms, and those results suggested that WT1 has oncogenic properties. The objective of the current study was to evaluate the prognostic significance of WT1 mRNA expression in patients with soft tissu...

journal_title：Cancer

authors： Sotobori T,Ueda T,Oji Y,Naka N,Araki N,Myoui A,Sugiyama H,Yoshikawa H

更新日期：2006-05-15 00:00:00

abstract：BACKGROUND:Aggressive non-Hodgkin's lymphoma is now often curable with chemotherapy. The International Prognostic Index (IPI) was recently developed to predict patient survival on the basis of pretreatment clinical features. However, classical multivariate regression models such as the IPI fail to detect time-dependent...

journal_title：Cancer

authors： Mounier N,Morel P,Haioun C,Coiffier B,Tilly H,Chatelain C,Lederlin P,Thyss A,Herbrecht R,Gisselbrecht C,Lepage E

更新日期：1998-05-15 00:00:00

abstract：:Elective irradiation of sites of potential occult tumor spread is often part of a patient's radiation therapy program. The required radiation dose (D) depends on the probability that occult disease exists (P(occ)), the number of sites at risk (A), the number of tumor clonogens present (Ni), their radiation sensitivity...

journal_title：Cancer

authors： Marks LB

更新日期：1990-12-15 00:00:00

abstract：:Flow cytometric measurements were done on 51 ovarian carcinoma specimens collected from consecutive patients in a prospective study. The ploidy status was related to the course of the disease. The tumors from 26 (52%) of 50 evaluable patients had DNA aneuploidy. Patients with diploid tumors were more often considered ...

journal_title：Cancer

authors： Iversen OE

更新日期：1988-03-01 00:00:00

abstract：BACKGROUND:Five-year survival rates after resection of liver metastases from colorectal carcinoma are close to 25%. Recurrences occur in two-thirds of the patients after surgery. Selection of patients likely to benefit from surgery remains controversial and subjective. METHODS:Data from 1568 patients with resected liv...

journal_title：Cancer

authors： Nordlinger B,Guiguet M,Vaillant JC,Balladur P,Boudjema K,Bachellier P,Jaeck D

更新日期：1996-04-01 00:00:00

abstract：BACKGROUND:Significant antitumor effects were previously observed with radioimmunotherapy (RIT) using an anti-carcinoembryonic antigen (CEA) monoclonal antibody (F6) labeled with iodine-131 in medullary thyroid cancer (MTC)-bearing nude mice. Nevertheless, no complete response was achieved. Because angiogenesis is crit...

journal_title：Cancer

authors： Salaun PY,Bodet-Milin C,Frampas E,Oudoux A,Saï-Maurel C,Faivre-Chauvet A,Barbet J,Paris F,Kraeber-Bodéré F

更新日期：2010-02-15 00:00:00

abstract：BACKGROUND:Fas (CD95/APO-1) and Fas ligand (FasL) play key roles in immunologic homeostasis and immune privilege and may regulate normal cell turnover. Earlier studies had suggested that FasL-positive pancreatic carcinoma cell lines can induce apoptosis in T cells, thereby evading host immune surveillance. In the curre...

journal_title：Cancer

authors： Bernstorff WV,Glickman JN,Odze RD,Farraye FA,Joo HG,Goedegebuure PS,Eberlein TJ

更新日期：2002-05-15 00:00:00

abstract：BACKGROUND:Radiofrequency (RF)-induced tissue coagulation represents a new approach for the thermal destruction of tumors within the liver. The purpose of the current study was to 1) assess technique safety; 2) determine the extent and evolution of induced cellular damage; and 3) correlate the observed pathologic effec...

journal_title：Cancer

authors： Goldberg SN,Gazelle GS,Compton CC,Mueller PR,Tanabe KK

更新日期：2000-06-01 00:00:00

abstract：BACKGROUND:While the question of whether the trials of breast cancer screening have resulted in a reduction in breast cancer death has been the subject of much scrutiny, there has been less attention to the reduction in tumor size achieved by screening. METHODS:Size data for invasive breast tumors were assembled from ...

journal_title：Cancer

authors： Michaelson JS,Satija S,Kopans D,Moore R,Silverstein M,Comegno A,Hughes K,Taghian A,Powell S,Smith B

更新日期：2003-11-15 00:00:00

abstract：BACKGROUND:The inherited, low-penetrance arginine-to-histidine substitution at codon 337 (R337H) of the tumor protein 53 gene (TP53) is clustered in southeast Brazil (estimated frequency, 0.3%). Although its tumorigenic effect initially appeared to be tissue-specific, recent evidence suggests its association with a bro...

journal_title：Cancer

authors： Seidinger AL,Mastellaro MJ,Paschoal Fortes F,Godoy Assumpção J,Aparecida Cardinalli I,Aparecida Ganazza M,Correa Ribeiro R,Brandalise SR,Dos Santos Aguiar S,Yunes JA

更新日期：2011-05-15 00:00:00

abstract：BACKGROUND:Carcinomas of the small intestine are rare, but the risk is greatly increased in patients with hereditary nonpolyposis colorectal cancer (HNPCC) due to an inherited mismatch repair (MMR) gene mutation, most commonly affecting the genes MLH1 or MSH2. Defective MMR is characterized by microsatellite instabilit...

journal_title：Cancer

authors： Planck M,Ericson K,Piotrowska Z,Halvarsson B,Rambech E,Nilbert M

更新日期：2003-03-15 00:00:00

abstract：:The prognostic significance of ploidy level was studied in prostatic carcinoma and compared with the prognostic significance of morphologic grade and clinical stage. A nonselected group of 145 patients was studied in whom prostatic carcinoma was diagnosed by fine-needle aspiration biopsy at the Karolinska Hospital in ...

journal_title：Cancer

authors： Forsslund G,Esposti PL,Nilsson B,Zetterberg A

更新日期：1992-03-15 00:00:00

abstract：:The incidence of long thoracic nerve palsy after radical mastectomy has been documented to be approximately 10%. No cases have been reported after the more recent treatment for breast cancer, lumpectomy with axillary dissection. This more recent surgical procedure is customarily followed by aggressive radiation therap...

journal_title：Cancer

authors： Pugliese GN,Green RF,Antonacci A

更新日期：1987-09-15 00:00:00

abstract：:A primary cardiac spindle cell tumor with immunoreactivity for keratin proteins is reported. Cytogenetic analysis of the tumor demonstrated a translocation (X;18), an aberration almost exclusively reported in synovial sarcomas. Postmortem examination revealed amphibole asbestos within the lungs and diaphragmatic pleur...

journal_title：Cancer

authors： Karn CM,Socinski MA,Fletcher JA,Corson JM,Craighead JE

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:The presence of urinary excretion products of human chorionic gonadotropin (hCG) has been proposed as a tumor marker. To ascertain the clinical value in gynecologic cancers, the authors studied 612 nonpregnant women. METHODS:Three different assays in four clinical groups were compared: no disease, benign di...

journal_title：Cancer

authors： Neven P,Iles RK,Lee CL,Hudson CN,Shepherd JH,Chard T

更新日期：1993-06-15 00:00:00

abstract：BACKGROUND:The Centers for Disease Control and Prevention (CDC) initiated the Colorectal Cancer Screening Demonstration Program (CRCSDP) to explore the feasibility of establishing a large-scale colorectal cancer screening program for underserved populations in the United States. The authors of the current report provid...

journal_title：Cancer

authors： Subramanian S,Tangka FK,Hoover S,Beebe MC,DeGroff A,Royalty J,Seeff LC

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:Nonsmall cell lung carcinomas (NSCLCs) are associated with very dismal prognoses, and adjuvant chemotherapy, including irinotecan, taxanes, platin, and vinca alkaloid derivatives, offer patients only slight clinical benefits. Part of the chemoresistance of NSCLC results from the expression in NSCLC cells of ...

journal_title：Cancer

authors： Mathieu A,Remmelink M,D'Haene N,Penant S,Gaussin JF,Van Ginckel R,Darro F,Kiss R,Salmon I

更新日期：2004-10-15 00:00:00

abstract：:Intersitial pneumonia and pulmonary fibrosis developed in a 72-year-old man during therapy with cyclophosphamide, vincristine, and prednisone. After extensive investigations, including an open lung biopsy, cyclophosphamide appeared to be the cause of the pulmonary disease. Complete disappearance of tachypnea and the p...

journal_title：Cancer

authors： Patel AR,Shah PC,Rhee HL,Sassoon H,Rao KP

更新日期：1976-10-01 00:00:00

abstract：BACKGROUND:Genes involved in the angiopoietin and pericyte pathways may become escape mechanisms under antivascular endothelial growth factor (anti-VEGF) therapy. The authors investigated whether variations within genes in these pathways are associated with clinical outcome in patients with colorectal liver metastases ...

journal_title：Cancer

authors： Stremitzer S,Zhang W,Yang D,Ning Y,Stintzing S,Sebio A,Sunakawa Y,Yamauchi S,Matsusaka S,El-Khoueiry R,Stift J,Wrba F,Gruenberger T,Lenz HJ

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:A considerable body of evidence supports the concept that a significant number of cutaneous malignant melanomas progress through a precursor lesion or dysplastic melanocytic nevi (DN). Tumor angiogenesis likely plays a critical role in early development of melanoma, and intermediate biomarkers of angiogenesi...

journal_title：Cancer

authors： Einspahr JG,Thomas TL,Saboda K,Nickolof BJ,Warneke J,Curiel-Lewandrowski C,Ranger-Moore J,Duckett L,Bangert J,Fruehauf JP,Alberts DS

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND:Although state Medicaid programs cover cancer screening, Medicaid beneficiaries are less likely to be screened for cancer and are more likely to present with tumors of an advanced stage than are those with other insurance. The current study was performed to determine whether state Medicaid eligibility and re...

journal_title：Cancer

authors： Halpern MT,Romaire MA,Haber SG,Tangka FK,Sabatino SA,Howard DH

更新日期：2014-10-01 00:00:00