Imaging for improved prediction of myelotoxicity after radioimmunotherapy.

abstract：:A study of primary epithelial neoplasms of the appendix (with the exception of classical carcinoids), produced 24 adenocarcinomas and 42 benign lesions from the files of the Laboratory of Surgical Pathology of Columbia University. Invasive adenoarcinomas were often complicated by appendicitis and were then unexpectedl...

journal_title：Cancer

authors： Wolff M,Ahmed N

更新日期：1976-05-01 00:00:00

abstract：:The value of the serum level of carcinoembryonic antigen (CEA) as an indicator of recurrent colorectal carcinoma has been accepted, and the use of serial CEA levels to monitor postoperative chemotherapy has been suggested, However, elevated CEA levels may be associated with nonneoplastic conditions, of which the most ...

journal_title：Cancer

authors： Savrin RA,Martin EW Jr

更新日期：1981-02-01 00:00:00

abstract：:Results from the standpoint of survival rates and locoregional failures are compared in three series of patients having had a radical mastectomy for breast cancer: (1) radical mastectomy alone for the patients who had essentially outer quadrant lesions and a negative axilla; (2) postoperative irradiation when the axil...

journal_title：Cancer

authors： Rodger A,Montague ED,Fletcher G

更新日期：1983-04-15 00:00:00

abstract：:The percentage of T lymphocytes that form rosettes (RFC) with sheep erythrocytes (E rosettes), cutaneous delayed-type hypersensitivity, and in vitro lymphocyte transformation was measured in 15 patients with primary intracranial tumors. The ability of T lymphocytes to form E rosettes was significantly impaired. Thes...

journal_title：Cancer

authors： Brooks WH,Roszman TL,Rogers AS

更新日期：1976-04-01 00:00:00

abstract：BACKGROUND:Because angiogenesis may play a role in the pathogenesis of acute myeloid leukemia (AML) and high-risk myelodysplastic syndrome (MDS), and thalidomide (Th) has shown significant anti-angiogenic activity, this study was designed to investigate the potential role of Th in the treatment of patients with AML and...

journal_title：Cancer

authors： Cortes J,Kantarjian H,Albitar M,Thomas D,Faderl S,Koller C,Garcia-Manero G,Giles F,Andreeff M,O'Brien S,Keating M,Estey E

更新日期：2003-03-01 00:00:00

abstract：:The study is a clinicopathologic report on 64 patients with primary adenocarcinoma of the urinary bladder and urachus, with particular reference to important prognostic and therapeutic factors. All tumors exhibited adenocarcinomatous features in at least two thirds of the examined tumor area. Pure forms of the differe...

journal_title：Cancer

authors： Anderström C,Johansson SL,von Schultz L

更新日期：1983-10-01 00:00:00

abstract：BACKGROUND:Disruption of the lymphatic circulation through breast carcinoma-associated axillary lymph node dissection, with or without radiation therapy, reportedly is the most common cause of lymphedema in developed countries. There is no cure for breast carcinoma-associated lymphedema. Although intermittent pneumatic...

journal_title：Cancer

authors： Szuba A,Achalu R,Rockson SG

更新日期：2002-12-01 00:00:00

abstract：:Fifty patients with inoperable squamous carcinoma of the lung. 38 with extensive, and 12 with limited disease, were treated with BACON. Tumor regression greater than 50% was observed in 17 patients (45%) with extensive, and four patients (33%) with limited disease. Stabilization of disease for greater than or equal to...

journal_title：Cancer

authors： Livingston RB,Fee WH,Einhorn LH,Burgess MA,Freireich EJ,Gottlieb JA,Farber MO

更新日期：1976-03-01 00:00:00

abstract：BACKGROUND:Uterine leiomyosarcoma (ULMS) is identified in 0.1% to 0.2% of hysterectomy specimens of presumed leiomyoma. To date, there is no preoperative technique that reliably differentiates ULMS from uterine leiomyoma. Increasing use of minimally invasive approaches for the management of leiomyomas may result in ina...

journal_title：Cancer

authors： George S,Barysauskas C,Serrano C,Oduyebo T,Rauh-Hain JA,Del Carmen MG,Demetri GD,Muto MG

更新日期：2014-10-15 00:00:00

abstract：BACKGROUND:Clear cell sarcoma (CCS) of tendons and aponeuroses is extremely rare in childhood and little information is available on its clinical management. Originally believed to be a type of melanoma of soft tissue origin, CCS is now considered a distinct clinicopathologic entity that behaves like a high-grade soft ...

journal_title：Cancer

authors： Ferrari A,Casanova M,Bisogno G,Mattke A,Meazza C,Gandola L,Sotti G,Cecchetto G,Harms D,Koscielniak E,Treuner J,Carli M

更新日期：2002-06-15 00:00:00

abstract：BACKGROUND:The current study was performed to describe patient characteristics, treatment patterns, survival, health care resource use (HRU), and costs among older women in the United States with advanced (American Joint Committee on Cancer stage III/IV) triple-negative breast cancer (TNBC) in the Surveillance, Epidemi...

journal_title：Cancer

authors： Schwartz KL,Simon MS,Bylsma LC,Ruterbusch JJ,Beebe-Dimmer JL,Schultz NM,Flanders SC,Barlev A,Fryzek JP,Quek RGW

更新日期：2018-05-15 00:00:00

abstract：BACKGROUND:This study was conducted to evaluate whether estramustine (estrogen mustard [EM]) is a promising alternative in the treatment of patients with epithelial ovarian carcinoma (OVCA). EM is a microtubule-associated protein (MAP) specific antimicrotubule agent with low toxicity. METHODS:The authors investigated ...

journal_title：Cancer

authors： Chen Z,Fadiel A,Jia JF,Sakamoto H,Carbone R,Naftolin F

更新日期：1999-06-15 00:00:00

abstract：:The acquisition by tumor cells of the ability to metastasize is the critical event in the clinical course of most human neoplastic disease. While metastasis plays a pivotal role in the ultimate success of failure of therapy, it is in fact a result of a more insidious malignant process termed tumor progression. It is t...

journal_title：Cancer

authors： Frost P,Fidler IJ

更新日期：1986-07-15 00:00:00

abstract：:A case of an acute myocardial infarction occurring in a 19-year-old woman, 27 months after mantle radiotherapy for Stage II-A Hodgkin's disease is described. The coronary arteriogram demonstrated patent and normal coronary arteries, but the echocardiogram revealed pericarditis. The clinical course was further complica...

journal_title：Cancer

authors： Yahalom J,Hasin Y,Fuks Z

更新日期：1983-08-15 00:00:00

abstract：:A 45-year-old man was diagnosed with multiple myeloma, IgA-kappa, in 1975. Thirteen years later he presented with obstructive jaundice. Computed tomography (CT) showed a 6-cm mass in the head of the pancreas. Needle aspiration showed myeloma. The jaundice resolved after treatment with radiotherapy. Extraosseous involv...

journal_title：Cancer

authors： Fischer A,Suhrland MJ,Vogl SE

更新日期：1991-02-01 00:00:00

abstract：BACKGROUND:Conditional survival (CS) has emerged as a clinically relevant measure of prognosis for cancer survivors. The objective of this analysis was to provide melanoma-specific CS estimates to help clinicians promote more informed patient decision making. METHODS:Patients with melanoma and at least 5 years of foll...

journal_title：Cancer

authors： Xing Y,Chang GJ,Hu CY,Askew RL,Ross MI,Gershenwald JE,Lee JE,Mansfield PF,Lucci A,Cormier JN

更新日期：2010-05-01 00:00:00

abstract：:The effect of cis-diamminedichloroplatinum II (DDP) and ionizing radiation on human bladder transitional cell carcinoma (TCC) was evaluated in nude mouse-grown human tumors following administration of single-agent and combination treatment. Combination of DDP and radiation resulted in accelerated tumor regression and ...

journal_title：Cancer

authors： Kyriazis AP,Yagoda A,Kereiakes JG,Kyriazis AA,Whitmore WF Jr

更新日期：1983-08-01 00:00:00

abstract：:The incidence of ovarian cancer in Rochester, Minnesota over the 40-year period 1935 through 1974 was determined; and risk factors for epithelial ovarian cancer occurring in Rochester from 1945 to 1974 were examined in 116 patients and 464 controls. Among the characteristics studied, only nulliparity was found to be a...

journal_title：Cancer

authors： Annegers JF,Strom H,Decker DG,Dockerty MB,O'Fallon WM

更新日期：1979-02-01 00:00:00

abstract：BACKGROUND:Acquired Glanzmann's thrombasthenia is a rare hemorrhagic diathesis resulting from impaired adhesive function of the platelet receptor GPIIb/IIIa (alpha(IIb)beta3). Typically, this disorder develops during adulthood, with patients manifesting fluctuating clinical and laboratory findings. To date, the underly...

journal_title：Cancer

authors： Malik U,Dutcher JP,Oleksowicz L

更新日期：1998-05-01 00:00:00

abstract：BACKGROUND:Primary small cell carcinoma arising in organs other than the lung were thought to be relatively rare. However, with the increasing technical sophistication of pathology departments, tumors with foci of small cell neuroendocrine components are being identified more frequently. The pattern of disease involvem...

journal_title：Cancer

authors： Lyster MT,Kies MS,Kuzel TM

更新日期：1994-12-15 00:00:00

abstract：:Flow cytometric analysis of nuclear DNA content was performed on excised malignant tissue of the esophagus. The DNA ploidy pattern was compared with a variety of histologic parameters and the subsequent clinical course to determine whether or not this pattern is associated with the mode of malignant potentiality. Of t...

journal_title：Cancer

authors： Kaketani K,Saito T,Kobayashi M

更新日期：1989-08-15 00:00:00

abstract：BACKGROUND:Adult "translocation" renal cell carcinoma (RCC), bearing transcription factor E3 (TFE3) gene fusions at Xp11.2, is a recently recognized, unique entity for which prognosis and therapy remain poorly understood. In the current study, the authors investigated the effect of vascular endothelial growth factor (V...

journal_title：Cancer

authors： Choueiri TK,Lim ZD,Hirsch MS,Tamboli P,Jonasch E,McDermott DF,Dal Cin P,Corn P,Vaishampayan U,Heng DY,Tannir NM

更新日期：2010-11-15 00:00:00

abstract：:The authors investigated the level of lipid peroxidation and possible related phenomena in the activation of phospholipase A2 and the infiltration of granulocyte neutrophils in human colorectal cancer tissue samples. Malondialdehyde (an index of lipid peroxidation), phospholipase A2 activity, and myeloperoxidase activ...

journal_title：Cancer

authors： Otamiri T,Sjödahl R

更新日期：1989-07-15 00:00:00

abstract：BACKGROUND:Indium-111 labeled antiferritin targets 95% of all Hodgkin's disease lesions with a diameter of 1 cm or more. Subsequent treatment with yttrium-90 labeled antiferritin secures a high response rate in patients with recurrent Hodgkin's disease. METHODS:A total of 87 patients were entered on one of three diffe...

journal_title：Cancer

authors： Vriesendorp HM,Quadri SM,Andersson BS,Wyllie CT,Dicke KA

更新日期：1997-12-15 00:00:00

abstract：:Platelet kinetics were studied in 70 patients with testicular cancer to elicit the agent responsible for chemotherapy-induced transient early-onset thrombocytopenia; 204 treatment courses were analyzed using three different therapy protocols, which contained vinblastine and bleomycin either alone or in combination wit...

journal_title：Cancer

authors： Steurer G,Kuzmits R,Pavelka M,Sinzinger H,Fritz E,Ludwig H

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:Gastrointestinal stromal tumors (GISTs) are KIT-positive mesenchymal tumors of the gastrointestinal tract that are driven by activated KIT-signalling or platelet-derived growth factor receptor-alpha (PDFGRA) signaling. These tumors most commonly occur in the stomach and small intestine and encompass a clinic...

journal_title：Cancer

authors： Miettinen M,Kraszewska E,Sobin LH,Lasota J

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:Lymphocyte-predominant Hodgkin lymphoma (LPHL) is a rare, CD20-positive, good prognostic lymphoma in children. Patients with early-stage LPHL who underwent successful surgical lymph node resection alone have been reported. To clarify the optimum treatment strategy in children, European study groups were aske...

journal_title：Cancer

authors： Mauz-Körholz C,Gorde-Grosjean S,Hasenclever D,Shankar A,Dörffel W,Wallace WH,Schellong G,Robert A,Körholz D,Oberlin O,Hall GW,Landman-Parker J

更新日期：2007-07-01 00:00:00

abstract：:The glucose consumption rate of 9L rat brain tumor cells was determined as a function of concentration. Glucose uptake followed Michaelis-Menten kinetics with a Km of 0.58 mM and a Vmax of 1.6 pg/cell-min. The glucose diffusion coefficient in spheroids of 9L tumor cells was determined to be 1.5 x 10(-6) cm2/s at 37 de...

journal_title：Cancer

authors： Li CK

更新日期：1982-11-15 00:00:00

abstract：BACKGROUND:Aberrant DNA methylation, which results in leukemogenesis, is frequent in patients with myelodysplastic syndromes (MDS) and is a potential target for pharmacologic therapy. Decitabine indirectly depletes methylcytosine and causes hypomethylation of target gene promoters. METHODS:A total of 170 patients with...

journal_title：Cancer

authors： Kantarjian H,Issa JP,Rosenfeld CS,Bennett JM,Albitar M,DiPersio J,Klimek V,Slack J,de Castro C,Ravandi F,Helmer R 3rd,Shen L,Nimer SD,Leavitt R,Raza A,Saba H

更新日期：2006-04-15 00:00:00

abstract：BACKGROUND:CXC chemokine receptor 4 (CXCR4) is activated by phosphorylation (pCXCR4) and is essential for the migration of hematopoietic precursors to bone marrow. CXCR4 overexpression predicts a poor prognosis in patients with acute myeloid leukemia. Data regarding the prognostic impact of CXCR4 in patients with B-acu...

journal_title：Cancer

authors： Konoplev S,Jorgensen JL,Thomas DA,Lin E,Burger J,Kantarjian HM,Andreeff M,Medeiros LJ,Konopleva M

更新日期：2011-10-15 00:00:00