Abstract:
:The percentage of T lymphocytes that form rosettes (RFC) with sheep erythrocytes (E rosettes), cutaneous delayed-type hypersensitivity, and in vitro lymphocyte transformation was measured in 15 patients with primary intracranial tumors. The ability of T lymphocytes to form E rosettes was significantly impaired. These patients also exhibited impaired ability to become sensitized to dinitrochlorobenzene and humoral suppression of PHA-induced lymphocyte blastogenesis. The hypothetical role of antibody(s) to possible shared antigenic determinants on brain and T cells is discussed.
journal_name
Cancerjournal_title
Cancerauthors
Brooks WH,Roszman TL,Rogers ASdoi
10.1002/1097-0142(197604)37:4<1869::aid-cncr282037subject
Has Abstractpub_date
1976-04-01 00:00:00pages
1869-73issue
4eissn
0008-543Xissn
1097-0142journal_volume
37pub_type
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