The spectrum of cytologic features in nonproliferative breast lesions.

abstract：:For women who are candidates for menopausal hormone therapy (MHT), estrogen can provide relief from symptomatic menopause, decrease rates of chronic illnesses, and improve health-related quality of life. However, confusion surrounds the evidence regarding the impact of exogenous estrogen and progesterone on the breast...

journal_title：Cancer

authors： Temkin SM,Mallen A,Bellavance E,Rubinsak L,Wenham RM

更新日期：2019-02-15 00:00:00

abstract：BACKGROUND:The activation of the clotting-fibrinolytic system in cancer patients is common and represents an unfavorable clinical sign. D-dimer (DD) is a sensitive marker of fibrinolysis. METHODS:The current study comprised 826 new lung carcinoma patients seen consecutively in a single institution over a 10-year perio...

journal_title：Cancer

authors： Buccheri G,Torchio P,Ferrigno D

更新日期：2003-06-15 00:00:00

abstract：BACKGROUND:Stomatitis has been found to be a major dose-limiting toxicity from bolus 5-fluorouracil-based (5-FU) chemotherapy regimens, despite the use of oral cryotherapy. Pursuant to preliminary data which suggested that a chamomile mouthwash might ameliorate this toxicity, a prospective trial was developed to test c...

journal_title：Cancer

authors： Fidler P,Loprinzi CL,O'Fallon JR,Leitch JM,Lee JK,Hayes DL,Novotny P,Clemens-Schutjer D,Bartel J,Michalak JC

更新日期：1996-02-01 00:00:00

abstract：:Between 1964 and 1982, 862 patients with acute leukemia who were collected from medical institutions throughout the country had a survival of 5 years or longer. Their remission has been achieved mainly with a combination therapy of vincristine and prednisone in childhood acute leukemia and daunomycin, cytosine arabino...

journal_title：Cancer

authors： Kawashima K,Nagura E,Yamada K,Hamajima N

更新日期：1985-07-01 00:00:00

abstract：:Numerous examples exist of prognostic factors that have been conclusively established and that can segregate the target patient population into subgroups with vastly different outcomes. At the same time, we can expect, in the majority of trials being conducted, that if a new treatment turns out to be successful, it ge...

journal_title：Cancer

authors： Sather HN

更新日期：1986-07-15 00:00:00

abstract：BACKGROUND:Current adjuvant hormone therapy in postmenopausal women with breast cancer is debatable between upfront aromatase inhibitors (AIs) and sequential treatment with tamoxifen. A major concern is the higher rate of early recurrences observed with sequential treatment. The authors conducted a retrospective analys...

journal_title：Cancer

authors： Debled M,MacGrogan G,Brouste V,Mathoulin-Pelissier S,Durand M,Mauriac L

更新日期：2007-06-01 00:00:00

abstract：:Twelve patients who presented with extranodal small lymphocytic proliferations were studied. The patients ranged in age from 33 to 67 years; six were male and six female. Locations of the initial lesion included the conjunctiva and orbit, lung, stomach, small bowel, skin, and subcutis. The histopathologic picture in a...

journal_title：Cancer

authors： Evans HL

更新日期：1982-01-01 00:00:00

abstract：:Autopsy data of 423 cases of primary tumor of the lung over a 36-year period were evaluated for the presence of gastrointestinal tract metastases. Fifty-eight cases (14%) were found and were analyzed for histologic nature of tumor, anatomic location, symptomatology and complications. The most common histologic type of...

journal_title：Cancer

authors： Antler AS,Ough Y,Pitchumoni CS,Davidian M,Thelmo W

更新日期：1982-01-01 00:00:00

abstract：:Serum trace elements (STE) were measured in 50 patients with chronic lymphocytic leukemia (CLL) and 100 normal subjects. Copper was higher in patients than in controls (1.50 +/- 0.06 versus 1.10 +/- 0.02 micrograms/ml, P less than 0.001), increased steadily from Stage 0 to Stage 4 (P = 0.002), and correlated with the ...

journal_title：Cancer

authors： Beguin Y,Brasseur F,Weber G,Bury J,Delbrouck JM,Roelandts I,Robaye G,Fillet G

更新日期：1987-10-15 00:00:00

abstract：BACKGROUND:RUNX3 is a tumor suppressor that plays important roles in cell proliferation, apoptosis, and metastasis. The authors investigated the role of RUNX3 in melanoma pathogenesis and analyzed the prognostic impact of RUNX3 expression in a large series of melanoma patients. METHODS:Two sets of tissue microarrays w...

journal_title：Cancer

authors： Zhang Z,Chen G,Cheng Y,Martinka M,Li G

更新日期：2011-06-15 00:00:00

abstract：BACKGROUND:In many areas of health care, whether patients receive specific medical interventions often is influenced heavily by the local availability of resources for delivering those services. However, relations between resource availability and utilization are relatively unexplored in cancer care, including perioper...

journal_title：Cancer

authors： Wong SL,Wei Y,Birkmeyer JD

更新日期：2007-02-15 00:00:00

abstract：:Twenty-two children with acute lymphocytic leukemia (ALL) who had relapsed while on therapy and for whom remissions were successfully reinduced were maintained with a combination of methotrexate, daunomycin, 6-mercaptopurine, prednisone, and vincristine (Djerassi-methotrexate with BOMB). The median duration of remissi...

journal_title：Cancer

authors： Kimball JC,Herson J,Sullivan MP

更新日期：1980-09-01 00:00:00

abstract：BACKGROUND:Aggressive non-Hodgkin's lymphoma is now often curable with chemotherapy. The International Prognostic Index (IPI) was recently developed to predict patient survival on the basis of pretreatment clinical features. However, classical multivariate regression models such as the IPI fail to detect time-dependent...

journal_title：Cancer

authors： Mounier N,Morel P,Haioun C,Coiffier B,Tilly H,Chatelain C,Lederlin P,Thyss A,Herbrecht R,Gisselbrecht C,Lepage E

更新日期：1998-05-15 00:00:00

abstract：:The close observation of patients treated for testicular cancer led to the suspicion of intrathoracic and/or mediastinal metastases on radiologic examination in a number of patients without other evidence of relapse. This report presents two patients with combined seminomatous and nonseminomatous germ cell tumors with...

journal_title：Cancer

authors： Looijen R,Hoekstra HJ,Sleijfer DT,Postmus P,Oosterhuis JW,de Boer WJ,Schraffordt Koops H

更新日期：1990-11-15 00:00:00

abstract：BACKGROUND:Paclitaxel currently is administered by prolonged intravenous infusion because of the occurrence of severe hypersensitivity reactions in patients in early clinical trials. However, intensive premedication probably is more important in eliminating allergic reactions than is the length of infusion. The authors...

journal_title：Cancer

authors： Hainsworth JD,Greco FA

更新日期：1994-08-15 00:00:00

abstract：:In recent years, an increased understanding of T-cell-regulatory mechanisms has led to the development of a novel class of immune-checkpoint inhibitors that have robust clinical activity against a broad array of malignancies-even those that historically were not believed to be sensitive to immune therapy. With this, t...

journal_title：Cancer

authors： Salama AK,Postow MA,Salama JK

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:Adenocarcinomas of the appendix represent a heterogeneous disease depending on the presence of mucinous histology, histologic grade, and stage. In the current study, the authors sought to explore the interplay of these factors with systemic chemotherapy in a large population data set. METHODS:Patients in th...

journal_title：Cancer

authors： Asare EA,Compton CC,Hanna NN,Kosinski LA,Washington MK,Kakar S,Weiser MR,Overman MJ

更新日期：2016-01-15 00:00:00

abstract：:Chemotherapy for tumors of the central nervous system has a limited efficacy presumably because of restricted blood-brain barrier permeability. The advantage of regional intra-arterial administration of anticancer drugs is an increased uptake during the first passage of the drugs through tumor capillaries. Twenty pati...

journal_title：Cancer

authors： Madajewicz S,Chowhan N,Iliya A,Roque C,Beaton R,Davis R,Fertman S,Meek A,Alvarez O,Pampati M

更新日期：1991-06-01 00:00:00

abstract：BACKGROUND:Patients age > or = 75 years with acute myeloid leukemia (AML) generally are offered palliative treatments instead of induction chemotherapy. The authors conducted a retrospective study comparing the outcomes among these elderly patients with the outcomes among younger patients to assess the impact of intens...

journal_title：Cancer

authors： Vey N,Coso D,Bardou VJ,Stoppa AM,Braud AC,Bouabdallah R,Sainty D,Mozziconacci MJ,Lafage M,Damaj G,Blaise D,Gastaut JA,Maraninchi D

更新日期：2004-07-15 00:00:00

abstract：BACKGROUND:A randomized, multicenter trial, double-blind for antiandrogen therapy, compared the antiandrogens bicalutamide and flutamide, each combined with luteinizing hormone-releasing hormone analogue therapy (LHRH-A) in 813 patients with Stage D2 prostate carcinoma. An analysis of time to progression (median follow...

journal_title：Cancer

authors： Schellhammer PF,Sharifi R,Block NL,Soloway MS,Venner PM,Patterson AL,Sarosdy MF,Vogelzang NJ,Chen Y,Kolvenbag GJ

更新日期：1996-11-15 00:00:00

abstract：BACKGROUND:This paper gives an outline of the Casley-Smith method for the treatment of lymphedema of the arm. It includes a brief summary of the development of manual techniques and the terminology applied to them. METHODS:The four principles of this method are skin care, manual lymphatic drainage, compression in the ...

journal_title：Cancer

authors： Casley-Smith JR,Boris M,Weindorf S,Lasinski B

更新日期：1998-12-15 00:00:00

abstract：:Fourteen patients with adenocarcinoma of the gastrointestinal tract and pancreas treated with mitomycin C(MMC) and 5-fluorouracil (5-FU) had renal impairment 6-11 months from the beginning of MMC therapy. Two clinical entities were recognized: an acute fulminating renal failure that was rapidly fatal and a chronic slo...

journal_title：Cancer

authors： Hanna WT,Krauss S,Regester RF,Murphy WM

更新日期：1981-12-15 00:00:00

abstract：:Neuroblastoma is the most common neoplasm in children less than 1 year of age and has one of the earliest incidence peaks of all childhood cancers. Using birth registration data, a matched case-control study was undertaken to investigate potential prenatal and perinatal risk factors. Ninety-seven neuroblastoma patient...

journal_title：Cancer

authors： Neglia JP,Smithson WA,Gunderson P,King FL,Singher LJ,Robison LL

更新日期：1988-06-01 00:00:00

abstract：:Flow cytometry was used to compare binding of wheat germ agglutinin (WGA) and Lens culinaris lectin (Lcl) to peripheral lymphocytes (PBL) from normal subjects and 26 patients with chronic lymphocytic leukemia (CLL). As defined by the interactions of WGA and Lcl with cell surface receptors, normal unfractionated PBL an...

journal_title：Cancer

authors： Boldt DH,Nelson MO

更新日期：1983-06-01 00:00:00

abstract：BACKGROUND:The incidence of adenocarcinoma of the cervix did not decline in Western countries in the 1970s and 1980s despite the availability and use of cervical cytologic screening. The impact of improved endocervical sampling and better recognition of the cytologic precursors to adenocarcinoma during the 1990s in red...

journal_title：Cancer

authors： Mitchell H,Hocking J,Saville M

更新日期：2003-12-25 00:00:00

abstract：:A series of nine cases of radiation myelopathy seen at the University of California, San Francisco (UCSF) is reviewed, and their treatment data converted into nominal single doses (NSD) and equivalent single doses (ED). The 1% incidence level of myelopathy in the thoracic cord is 1015 rets (ED), and the 50% incidence...

journal_title：Cancer

authors： Wara WM,Phillips TL,Sheline GE,Schwade JG

更新日期：1975-06-01 00:00:00

abstract：:A bronchogenic tumor was removed from a 12-year-old girl. Histology showed a clear cell lesion with electron microscope features compatible with serous acinic cell origin. ...

journal_title：Cancer

authors： Katz DR,Bubis JJ

更新日期：1976-08-01 00:00:00

abstract：:The individual medical histories in the files of the Oxford Record Linkage Study for the years 1963 to 1967 were analyzed to ascertain any previously unsuspected associations between cancers of the large bowel and other diseases in individuals, and to quantify the relative risks of disorders already known to be associ...

journal_title：Cancer

authors： Adelstein P,Baldwin JA,Fedrich J

更新日期：1979-06-01 00:00:00

abstract：BACKGROUND:Obesity has been shown to affect breast carcinoma prognosis, with the heaviest women having a higher mortality due to breast carcinoma. Few studies have focused on premenopausal women or the correlation of body mass index (BMI) to tumor characteristics related to prognosis. METHODS:The authors conducted a p...

journal_title：Cancer

authors： Daling JR,Malone KE,Doody DR,Johnson LG,Gralow JR,Porter PL

更新日期：2001-08-15 00:00:00

abstract：:The case history of a woman with a "female adnexal tumor of probable Wolffian origin" is described in which the neoplasm recurred three times during a 16-year interval and responded with prolonged remission after repeated surgical excision and radiotherapy. Ultrastructural data are given to support the Wolffian nature...

journal_title：Cancer

authors： Brescia RJ,Cardoso de Almeida PC,Fuller AF Jr,Dickersin GR,Robboy SJ

更新日期：1985-09-15 00:00:00