Medical adrenalectomy in patients with advanced breast cancer.

abstract：:Eighty-six children with non-Hodgkin's lymphoma were studied from 1964 to January 31, 1975. Seventy-six percent of the 43 patients in the nonprotocol group had far advanced disease, and 76% had Rappaport's diffuse histology. Only 11% of these patients survived free of disease. The second group of 43 patients received ...

journal_title：Cancer

authors： Wollner N,Burchenal JH,Lieberman PH,Exelby P,D'Angio G,Murphy ML

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND:The aim of this retrospective study was to determine those prognostic factors associated with response to a second-line chemotherapy in patients with metastatic breast carcinoma (MBC) that was previously responsive to a first-line chemotherapy. METHODS:The 70 MBC patients studied had previously responded to...

journal_title：Cancer

authors： Brun B,Benchalal M,Lebas C,Piedbois P,Lin M,Lebourgeois JP

更新日期：1997-06-01 00:00:00

abstract：:A search of the records of 10 pediatric oncology centers revealed 102 children with more than one malignant neoplasm. In this group of 102 patients, all pediatric cancers were seen as initial lesions, but Wilms' tumor and retinoblastoma were over-represented and leukemia and brain tumors underrepresented. Survival var...

journal_title：Cancer

authors： Meadows AT,D'Angio GJ,Miké V,Banfi A,Harris C,Jenkin RD,Schwartz A

更新日期：1977-10-01 00:00:00

abstract：:A familial cancer aggregation comprising sarcomas, brain tumors, leukemias, and carcinomas of breast, larynx, lung, adrenal, cortex, and other sites has been studied from a pathologic--genetic standpoint. Based upon sibships segregating for cancer, the genetic segregation parameter is estimated to be 45.6 +/- 11% whi...

journal_title：Cancer

authors： Lynch HT,Mulcahy GM,Harris RE,Guirgis HA,Lynch JF

更新日期：1978-05-01 00:00:00

abstract：BACKGROUND:Recent clinical studies have demonstrated that tumor angiogenesis is a potent prognostic indicator for breast cancer patients. The quantitation of endothelial growth factors is thought to be useful to assess angiogenic phenotype in the tumor. Among the many new endothelial growth factors, vascular endothelia...

journal_title：Cancer

authors： Toi M,Kondo S,Suzuki H,Yamamoto Y,Inada K,Imazawa T,Taniguchi T,Tominaga T

更新日期：1996-03-15 00:00:00

abstract：BACKGROUND:The authors sought to determine whether differences existed in patterns of outcome and morbidity between the 3 thigh compartments after limb-sparing surgery and postoperative radiation therapy (RT). METHODS:A total of 255 patients with primary soft tissue sarcoma (STS) of the thigh were identified in our sa...

journal_title：Cancer

authors： Rimner A,Brennan MF,Zhang Z,Singer S,Alektiar KM

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Carfilzomib improves survival in patients with recurrent myeloma. Given the strict eligibility criteria in clinical trials, the actual frequency of cardiac adverse events (CAEs) and pulmonary adverse events (PAEs) and the risk factors associated with these AEs in the general population need to be established...

journal_title：Cancer

authors： Fakhri B,Fiala MA,Shah N,Vij R,Wildes TM

更新日期：2020-02-15 00:00:00

abstract：:The present overview of advanced prostate cancer required the identification of randomized clinical trials studying the question of maximal androgen blockade versus the classic castration therapy. The heterogeneity of the trials concerned the type of castration (surgical or chemical) and the type of antiandrogen (flut...

journal_title：Cancer

authors： Suciu S,Sylvester R,Iversen P,Christensen I,Denis L

更新日期：1993-12-15 00:00:00

abstract：:Biopsy specimens from 62 human single primary squamous cell carcinomas (SCC) of the head and neck were xenografted into nude mice. To evaluate the prognostic significance of successful heterotransplantation, the 62 cases were retrospectively examined for survival, adjusting for possible confounders by multivariate ana...

journal_title：Cancer

authors： Zätterström UK,Wennerberg J,Attewell R,Ask A

更新日期：1990-07-01 00:00:00

abstract：BACKGROUND:Cytogenetics and multicolor flow cytometry (MFC) are useful tools for monitoring outcome of treatment in acute myeloid leukemia (AML). However, no data are available regarding the meaning of results when the 2 tests do not agree. METHODS:The authors of this report analyzed 1464 pairs of concurrent cytogenet...

journal_title：Cancer

authors： Fang M,Storer B,Wood B,Gyurkocza B,Sandmaier BM,Appelbaum FR

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Many studies have tried to identify prognostic factors to guide the selection of patients at high risk for metastases in penile carcinoma. The authors evaluated human papillomavirus (HPV) status with respect to clinical features, incidence of metastases, and prognosis of penile carcinoma. METHODS:Human papi...

journal_title：Cancer

authors： Bezerra AL,Lopes A,Santiago GH,Ribeiro KC,Latorre MR,Villa LL

更新日期：2001-06-15 00:00:00

abstract：:The binding of soybean agglutinin (SBA) lectin to routinely processed surgical pathology material from cases of prostatic hyperplasia, atypical hyperplasia, and adenocarcinoma was studied using an immunoperoxidase technique. Positive staining was obtained in eight of eight cases of nodular hyperplasia, eight of eight ...

journal_title：Cancer

authors： Loy TS,Kyle J,Bickel JT

更新日期：1989-04-15 00:00:00

abstract：:A case of carcinoid tumor of the gallbladder associated with adenocarcinoma in a 56-year-old man is reported and a review of the literature is made. The tumor was a polypoid mass with a size of 5.5 X 4.0 X 2.8 cm. Histologically, the tumor showed carcinoid and adenocarcinoma with areas of mucous change. Tumor cells co...

journal_title：Cancer

authors： Wada A,Ishiguro S,Tateishi R,Ishikawa O,Matsui Y

更新日期：1983-05-15 00:00:00

abstract：:Seventy-six patients with malignant germ cell tumors of the ovary received vincristine, dactinomycin, and cyclophosphamide (VAC) postoperatively. Fifty-four were treated after removal of all gross disease. The majority of these remain disease-free. Indeed, only 15 (28%) have failed, including 11 of 24 with pure endode...

journal_title：Cancer

authors： Slayton RE,Park RC,Silverberg SG,Shingleton H,Creasman WT,Blessing JA

更新日期：1985-07-15 00:00:00

abstract：BACKGROUND:Several investigators have reported the ability to establish xenografts in nude mice from children with neuroblastomas, but a correlation of prognosis with this establishment and the growth patterns of the neuroblastomas has not been reported. METHODS:Tumor specimens from 58 children with neuroblastomas wer...

journal_title：Cancer

authors： George BA,Yanik G,Wells RJ,Martin LW,Soukup S,Ballard ET,Gartside PS,Lampkin BC

更新日期：1993-12-01 00:00:00

abstract：:Since 1972 plasma CEA levels of 25 cancer patients have been assayed to evaluate the reliability of CEA as an early indicator of recurrent gastrointestinal cancer. Identification of significant elevations in CEA levels required definition of exactly what a given value meant. Intraassay and interassay accuracy was dete...

journal_title：Cancer

authors： Martin EW Jr,James KK,Hurtubise PE,Catalano P,Minton JP

更新日期：1977-02-01 00:00:00

abstract：BACKGROUND:Mortality from invasive bladder cancer is common, even with high-quality care. Thus, the best opportunities to improve outcomes may precede the diagnosis. Although screening currently is not recommended, better medical care of patients who are at risk (ie, those with hematuria) has the potential to improve o...

journal_title：Cancer

authors： Hollenbeck BK,Dunn RL,Ye Z,Hollingsworth JM,Skolarus TA,Kim SP,Montie JE,Lee CT,Wood DP Jr,Miller DC

更新日期：2010-11-15 00:00:00

abstract：BACKGROUND:Alveolar soft part sarcoma (ASPS), chondrosarcoma (CS), chordoma, epithelioid sarcoma, and solitary fibrous tumor (SFT) are malignant tumors that are relatively resistant to chemotherapy and for which more effective drug therapy is needed. METHODS:The 5 listed subtypes were enrolled into a single indolent s...

journal_title：Cancer

authors： Schuetze SM,Bolejack V,Choy E,Ganjoo KN,Staddon AP,Chow WA,Tawbi HA,Samuels BL,Patel SR,von Mehren M,D'Amato G,Leu KM,Loeb DM,Forscher CA,Milhem MM,Rushing DA,Lucas DR,Chugh R,Reinke DK,Baker LH

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Low frequency epithelial cells in bone marrow from colorectal carcinoma patients are associated with an increased risk of recurrence and decreased survival. Current immunohistochemical approaches to detect epithelial cells in bone marrow aspirates rely on antibodies against cytokeratin 18 (CK18). The predict...

journal_title：Cancer

authors： Litle VR,Warren RS,Moore D 2nd,Pallavicini MG

更新日期：1997-05-01 00:00:00

abstract：:The clinical and histologic data from 12 patients with "reticulum cell sarcoma" (large cell lymphoma) presenting in the skin were reviewed. Moreover, when appropriate material was available additional immunological, cytochemical and ultrastructural techniques were used to define the nature of the neoplastic cells. Eig...

journal_title：Cancer

authors： Willemze R,Ruiter DJ,Van Vloten WA,Meijer CJ

更新日期：1982-10-01 00:00:00

abstract：BACKGROUND:The authors studied the benefit of performing histopathologic grading and DNA ploidy characterization with respect to patient survival in a series of 206 astrocytomas (AST) for which they obtained 134 complete clinical follow-ups. METHODS:The material analyzed came from archival material, i.e., formalin-fix...

journal_title：Cancer

authors： Salmon I,Kiss R,Dewitte O,Gras T,Pasteels JL,Brotchi J,Flament-Durand J

更新日期：1992-07-15 00:00:00

abstract：:The use of molecular techniques in cytopathology has become an accepted and billable practice for certain applications. Other applications still are in the developmental or experimental stages but may soon be clinically useful. The current study provides a review of these techniques including molecular detection of cl...

journal_title：Cancer

authors： Rimm DL

更新日期：2000-02-25 00:00:00

abstract：BACKGROUND:The malignant biological behavior of small-sized lung adenocarcinomas remains obscure, although understanding this feature is important for selecting appropriate treatment. In the current study, the authors evaluated malignancy grades of small adenocarcinomas using fluorodeoxyglucose-positron emission tomogr...

journal_title：Cancer

authors： Nakayama H,Okumura S,Daisaki H,Kato Y,Uehara H,Adachi S,Yoshimura M,Okada M

更新日期：2010-07-01 00:00:00

abstract：:To evaluate the frequency, etiology, and outcome of diffuse interstitial pneumonitis after treatment of children with Stage IV (favorable histologic type) Wilms' tumor using whole-lung and abdominal radiation therapy, and combination chemotherapy, all cases reported in such patients entered on National Wilms' Tumor St...

journal_title：Cancer

authors： Green DM,Finklestein JZ,Tefft ME,Norkool P

更新日期：1989-02-01 00:00:00

abstract：BACKGROUND:Optic pathway gliomas (OPGs) are commonly noted in pediatric oncology services. Radiotherapy is effective at controlling tumors, but has many undesirable late effects, especially in patients with neurofibromatosis. Chemotherapy is commonly used to preserve vision and delay or eliminate the need for radiother...

journal_title：Cancer

authors： Dodgshun AJ,Elder JE,Hansford JR,Sullivan MJ

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:The optimal weekly oral dose of sirolimus and intravenous nanoparticle albumin-bound paclitaxel (nab-paclitaxel) were evaluated. METHODS:A phase 1b study was performed to evaluate escalating doses of oral sirolimus (5-60 mg) on days 2, 9, and 16 with intravenous nab-paclitaxel (100 mg/m(2) ) on days 1, 8, a...

journal_title：Cancer

authors： Abu-Khalaf MM,Baumgart MA,Gettinger SN,Doddamane I,Tuck DP,Hou S,Chen N,Sullivan C,Lezon-Geyda K,Zelterman D,Hatzis C,Deshpande H,Digiovanna MP,Azodi M,Schwartz PE,Harris LN

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:Lung cancer (LC) is the most common fatal malignancy, but there are no useful tumor markers for diagnosis or monitoring. Mucin 1 has an established role as a marker in other malignancies, but has undergone limited assessment in LC. METHODS:Serum from 86 patients with LC and 24 with benign pulmonary disease ...

journal_title：Cancer

authors： Willsher PC,Xing PX,Clarke CP,Ho DW,McKenzie IF

更新日期：1993-11-15 00:00:00

abstract：:The clonal growth pattern of bone marrow and peripheral blood cells from 16 patients with clinically suspected chronic myelogenous leukemia (CML) was evaluated in the double-layer agar system. Cytogenetic studies were performed on parallel marrow and peripheral blood samples. In four cases a unique growth pattern emer...

journal_title：Cancer

authors： Selvaggi S,Wolman SR,Bornstein S,Edinger F

更新日期：1984-12-15 00:00:00

abstract：:Forty seven patients with early gastric cancer received a 30-minute intravenous injection of bromodeoxyuridine (BrdU), 1000 mg each 1 hour before laparotomy, to label tumor cells in the S phase. In 13 of 47 patients, specimens obtained by endoscopic biopsy were cultured in vitro at 37 degrees C for 1 hour under three ...

journal_title：Cancer

authors： Kamata T,Yonemura Y,Sugiyama K,Ooyama S,Kosaka T,Yamaguchi A,Miwa K,Miyazaki I

更新日期：1989-10-15 00:00:00

abstract：BACKGROUND:The Hanford Tribal Service Program offers technical assistance and health education to American Indian tribes in an area reported to be affected by radiation from the Hanford Nuclear Reservation, which was developed and operated by the United States federal government. This article describes strategies used ...

journal_title：Cancer

authors： Jensen RA

更新日期：1996-10-01 00:00:00