Carcinoma of the pancreas: review of MGH experience from 1963 to 1973. Analysis of surgical failure and implications for radiation therapy.

Abstract:

:A retrospective study was done of all patients who were seen for definitive treatment of adenocarcinoma of the pancreas at the Massachusetts General Hospital from 1963 to 1973. There were a total of 145 patients. Thirty-one patients were treated with radical surgery, with a 16% operative mortality, a 5-year crude survival rate of 15%, and a local recurrence rate of 50%. Sixty-two patients were treated with biopsy alone, with no 5-year survivors. In addition, there were 35 patients who did not have a radical surgical procedure performed only because of the extent of the local disease. It is proposed that postoperative irradiation may reduce the incidence of local failure after radical surgery, and that preoperative radiation therapy or radiation therapy alone would be an appropriate treatment of those patients in whom the local extent of disease is initially too far advanced to perform radical surgery.

journal_name

Cancer

journal_title

Cancer

authors

Tepper J,Nardi G,Sutt H

doi

10.1002/1097-0142(197603)37:3<1519::aid-cncr282037

subject

Has Abstract

pub_date

1976-03-01 00:00:00

pages

1519-24

issue

3

eissn

0008-543X

issn

1097-0142

journal_volume

37

pub_type

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