Bone-marrow examination in the staging of small-cell anaplastic carcinoma of the lung with special reference to subtyping. An evaluation of 203 consecutive patients.

abstract：BACKGROUND:This study was performed to develop a sensitive method for the detection of circulating hepatocellular carcinoma (HCC) cells in peripheral blood, in advance of the diagnosis of distant metastasis of HCC by conventional means. METHODS:Peripheral blood (5 ml) samples were obtained from 64 patients with HCC an...

journal_title：Cancer

authors： Komeda T,Fukuda Y,Sando T,Kita R,Furukawa M,Nishida N,Amenomori M,Nakao K

更新日期：1995-05-01 00:00:00

abstract：:Numerous examples exist of prognostic factors that have been conclusively established and that can segregate the target patient population into subgroups with vastly different outcomes. At the same time, we can expect, in the majority of trials being conducted, that if a new treatment turns out to be successful, it ge...

journal_title：Cancer

authors： Sather HN

更新日期：1986-07-15 00:00:00

abstract：:From November 1987 to April 1989, 1000 women 40 years or older underwent screening vaginal sonography at the University of Kentucky Medical Center (Lexington, KY). Patients included in this investigation were all asymptomatic and had no known pelvic abnormalities. Each ovary was measured in three planes and ovarian vo...

journal_title：Cancer

authors： van Nagell JR Jr,Higgins RV,Donaldson ES,Gallion HH,Powell DE,Pavlik EJ,Woods CH,Thompson EA

更新日期：1990-02-01 00:00:00

abstract：:Two trials of leucovorin (LV) and 5-fluorouracil (5-FU) in patients with metastatic colorectal cancer were done, both using a 3-day loading dose and then weekly doses to minimize toxicity. The first trial used LV administered by intravenous infusion with a constant dose of 5-FU 400 mg/m2, and the second trail used ora...

journal_title：Cancer

authors： Laufman LR,Brenckman WD Jr,Stydnicki KA,Morgan ED,Collier M,Knick VB,Duch DS,Mullin R,Ferone R

更新日期：1989-03-15 00:00:00

abstract：:Levels of immunoreactive ACTH and calcitonin (CT), as well as CEA, were determined serially in 144 patients with lung cancer and in 62 patients with metastatic carcinoma to the lungs. Patients with neoplasms not involving the lungs, with nonmalignant blood dyscrasias, and with chronic obstructive pulmonary disease wer...

journal_title：Cancer

authors： Krauss S,Macy S,Ichiki AT

更新日期：1981-05-15 00:00:00

abstract：BACKGROUND:Nilotinib is a potent, second-generation inhibitor of BCR-ABL1 tyrosine kinase and has been approved as frontline and salvage therapy for patients with chronic-phase chronic myeloid leukemia (CP-CML). METHODS:In this single-institution, phase 2 study, 122 patients with newly diagnosed CP-CML received niloti...

journal_title：Cancer

authors： Masarova L,Cortes JE,Patel KP,O'Brien S,Nogueras-Gonzalez GM,Konopleva M,Verstovsek S,Garcia-Manero G,Ferrajoli A,Kadia TM,Ravandi-Kashani F,Borthakur G,DellaSala S,Estrov Z,Jabbour EJ,Kantarjian HM

更新日期：2020-04-01 00:00:00

abstract：:Hepatoblastoma differs from the adult type of hepatoma in clinical and pathologic features. The ratio of fucosylation of serum alpha-fetoprotein (AFP) was determined in seven patients with hepatoblastoma and in 21 infants and children with otherwise elevated serum AFP, using the improved technique of lentil agglutinin...

journal_title：Cancer

authors： Tsuchida Y,Honna T,Fukui M,Sakaguchi H,Ishiguro T

更新日期：1989-06-01 00:00:00

abstract：:One hundred ninety patients who had advanced active Hodgkin's disease, lymphosarcoma, or reticulum cell sarcoma were treated with a combination of cyclophosphamide, vincristine, procarbazine, and prednisone (COPP) given in a cyclical fashion every month. Complete remission was produced in 91 of 138 (66%) patients with...

journal_title：Cancer

authors： Morgenfeld MC,Pavlovsky A,Suarez A,Somoza N,Pavlovsky S,Palau M,Barros CA

更新日期：1975-10-01 00:00:00

abstract：BACKGROUND:A survey of the distribution of human papillomavirus (HPV) types across the spectrum of cervical cytologic categories defined by the Bethesda 2001 guidelines was conducted with the objective of examining how HPV detection by polymerase chain reaction (PCR) analysis may benefit the management of patients who ...

journal_title：Cancer

authors： Evans MF,Adamson CS,Papillo JL,St John TL,Leiman G,Cooper K

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:Despite optimal therapy with surgery and radiotherapy, the prognosis of patients with glioblastomas remains poor. Stereotactic brachytherapy involves the accurate placement of radioactive isotopes within brain tumors, significantly increasing the dose of radiation that can be delivered to the tumor bed witho...

journal_title：Cancer

authors： Wen PY,Alexander E 3rd,Black PM,Fine HA,Riese N,Levin JM,Coleman CN,Loeffler JS

更新日期：1994-06-15 00:00:00

abstract：BACKGROUND:Postchemotherapy surgery is an essential component in the management of patients with metastatic germ cell tumors (GCT). The authors assessed their institutional experience of retroperitoneal lymph node dissection (RPLND) after multiple chemotherapy regimens for advanced GCT. METHODS:By analyzing the instit...

journal_title：Cancer

authors： Eggener SE,Carver BS,Loeb S,Kondagunta GV,Bosl GJ,Sheinfeld J

更新日期：2007-02-01 00:00:00

abstract：:Female genital tract involvement by hematologic neoplasms is uncommon and is usually associated with disseminated disease. Lymphoid neoplasms, which involve the cervix and uterus primarily, are usually of either diffuse large cell or small cleaved cell type, and rarely Burkitt's (small non-cleaved) lymphoma or granulo...

journal_title：Cancer

authors： Zutter MM,Gersell DJ

更新日期：1990-09-01 00:00:00

abstract：BACKGROUND:It has been suggested that tissue factor (TF) plays an important role in tumor metastasis. Its expression in sarcoma cells was reported to up-regulate the vascular endothelial growth factor (VEGF) gene and thereby enhance tumor angiogenesis, which is essential to tumor metastasis. Although many malignant tum...

journal_title：Cancer

authors： Seto S,Onodera H,Kaido T,Yoshikawa A,Ishigami S,Arii S,Imamura M

更新日期：2000-01-15 00:00:00

abstract：:Since primary lymphoma of bone (PLB) exhibits morphologic diversity and variability in individual survival, we analyzed the relationship between histopathologic features and biological behavior in 33 patients treated at the Massachusetts General Hospital. Three major histologic subgroups were identified, based on a va...

journal_title：Cancer

authors： Dosoretz DE,Raymond AK,Murphy GF,Doppke KP,Schiller AL,Wang CC,Suit HD

更新日期：1982-09-01 00:00:00

abstract：:There is justifiable excitement about the recent introduction of prophylactic vaccines against human papillomavirus (HPV) types 16 (HPV-16) and HPV-18. Preventing these infections theoretically could avert approximately 70% of cervical cancer cases worldwide. In the U.S., numerous influential advocates are calling for...

journal_title：Cancer

authors： Schiffman M

更新日期：2007-06-25 00:00:00

abstract：:This study evaluates residual disease in 28 B-cell chronic lymphocytic leukemia (B-CLL) patients who obtained a clinicohematologic remission after intensive chemotherapy. Sixteen of 28 patients (57%) showed a normal number of circulating B-lymphocytes, as demonstrated by the low percentage of mouse rosette-forming cel...

journal_title：Cancer

authors： Brugiatelli M,Callea V,Morabito F,Oliva B,Francia Di Celle P,Fierro MT,Neri A,Foa R

更新日期：1989-05-15 00:00:00

abstract：BACKGROUND:Although there is no doubt that bisphosphonates (BPs), specific inhibitors of osteoclasts, are beneficial for the treatment of bone metastases, their effects on visceral metastases are unclear. The effect of zoledronic acid (ZOL) was examined in vivo on lung metastasis progression and animal survival, and in...

journal_title：Cancer

authors： Ory B,Heymann MF,Kamijo A,Gouin F,Heymann D,Redini F

更新日期：2005-12-01 00:00:00

abstract：:Epithelioid sarcoma is an uncommon tumor characterized by its appearance in the distal extremities (especially the forearm, wrist, and ankle), the tendency to recur locally, and high probability of spread to regional lymph nodes. Most patients have been treated surgically, and the potential role of radiation therapy a...

journal_title：Cancer

authors： Shimm DS,Suit HD

更新日期：1983-09-15 00:00:00

abstract：:Despite few effective therapies, only a small percentage of patients diagnosed with myelodysplastic syndromes (MDS) in the United States are enrolled in prospective, interventional clinical trials. MDS-specific barriers to trial accrual include a high frequency of elderly patients with comorbid conditions, atypical di...

journal_title：Cancer

authors： Steensma DP,Brunner AM,DeZern AE,Garcia-Manero G,Komrokji RS,Odenike OS,Roboz GJ,Savona MR,Stone RM,Sekeres MA

更新日期：2018-12-15 00:00:00

abstract：BACKGROUND:The authors attempted to obtain shared proteins among lung carcinoma cells by column chromatographies. A glycoprotein with approximately 500 kDa isolated from QG56 cells showed an identical amino acid sequence to 90K/Mac-2 binding protein (M2BP). This protein has been reported to be highly expressed and to m...

journal_title：Cancer

authors： Ozaki Y,Kontani K,Hanaoka J,Chano T,Teramoto K,Tezuka N,Sawai S,Fujino S,Yoshiki T,Okabe H,Ohkubo I

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND:Interactions between bone marrow-derived cytokines, growth factors, and tumors play a critical role in both the homing of tumors to the bone and the development of bone metastasis. Bone is a storehouse of latent growth factors produced by stromal cells and osteoblasts that, when activated during osteoclastic...

journal_title：Cancer

authors： David Roodman G

更新日期：2003-02-01 00:00:00

abstract：BACKGROUND:In colorectal carcinoma, venous invasion has been related to patient survival. Liver metastasis develops more frequently when venous invasion is present. However, the histologic features and clinical significance of venous invasion are not well understood. METHODS:A histologic study of venous invasion in co...

journal_title：Cancer

authors： Ouchi K,Sugawara T,Ono H,Fujiya T,Kamiyama Y,Kakugawa Y,Mikuni J,Tateno H

更新日期：1996-12-01 00:00:00

abstract：:Melanomas of the choroid, ciliary body, and iris of the eye are collectively known as uveal melanomas. These cancers represent 5% of all melanoma diagnoses in the United States, and their age-adjusted risk is 5 per 1 million population. These less frequent melanomas are dissimilar to their more common cutaneous melano...

journal_title：Cancer

authors： Chattopadhyay C,Kim DW,Gombos DS,Oba J,Qin Y,Williams MD,Esmaeli B,Grimm EA,Wargo JA,Woodman SE,Patel SP

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:LAMP3 is a newly described hypoxia regulated gene of potential interest in hypoxia-induced therapy resistance and metastasis. The prognostic value of LAMP3 in breast cancer was investigated. METHODS:Expression levels of LAMP3 in breast cancer cell lines and patient tissues were determined by real-time polym...

journal_title：Cancer

authors： Nagelkerke A,Mujcic H,Bussink J,Wouters BG,van Laarhoven HW,Sweep FC,Span PN

更新日期：2011-08-15 00:00:00

abstract：BACKGROUND:The usefulness of fine-needle aspiration biopsy (FNAB) for the histologic subtyping of specific sarcomas still is somewhat controversial but is becoming increasingly popular in the U.S. METHODS:To determine the accuracy and usefulness of FNAB in the differential diagnosis of myxoid sarcoma, the authors retr...

journal_title：Cancer

authors： Kilpatrick SE,Ward WG,Bos GD

更新日期：2000-06-25 00:00:00

abstract：BACKGROUND:Previous data from the National Cancer Data Base have examined time trends in stage of disease, treatment patterns, and survival for selected cancers. The most current (1993) data for breast carcinoma are described here. METHODS:Five Calls for Data have yielded a total of 508,724 breast cancer cases diagnos...

journal_title：Cancer

authors： Winchester DP,Osteen RT,Menck HR

更新日期：1996-10-15 00:00:00

abstract：:The observation, in 1980, of a rapid increase in platelet counts as a result of administration of intravenous immunoglobulin (IVIG) in a patient with immune thrombocytopenic purpura (ITP) was followed by clinical studies confirming the efficacy of this new treatment alternative in ITP. Simultaneously, new sensitive as...

journal_title：Cancer

authors： Imbach P

更新日期：1991-09-15 00:00:00

abstract：:Pretreatment factors of prognostic value were sought in 54 consecutively treated cases of adult acute myelogenous leukemia. Twenty of 37 patients with a good (greater than 50%) pretreatment Karnofsky performance status (P.S.) achieved complete remission (C.R.), while only 1/17 with a poor P.S. achieved C.R. This diffe...

journal_title：Cancer

authors： Kansal V,Omura GA,Soong SJ

更新日期：1976-07-01 00:00:00

abstract：BACKGROUND:[(111)In]-diethylenetriamine pentaacetic acid (DTPA)-D-[Phe1]-octreotide (OctreoScan, Mallinckrodt Medical, Petten, The Netherlands), combined with single photon emission computed tomography (SPECT), has limited possibilities to detect small abdominal endocrine tumors. This study explores the efficacy of Oct...

journal_title：Cancer

authors： Ohrvall U,Westlin JE,Nilsson S,Juhlin C,Rastad J,Lundqvist H,Akerström G

更新日期：1997-12-15 00:00:00

abstract：BACKGROUND:Various chemotherapy agents, especially of the alkylating category, have been associated with premature ovarian failure but there is no quantitative evidence of chemotherapy-induced ovarian damage in humans. The aim was to quantify the impact of chemotherapy on primordial follicle reserve and stromal functio...

journal_title：Cancer

authors： Oktem O,Oktay K

更新日期：2007-11-15 00:00:00