Abstract:
:Clinically benign whole, untrimmed prostates and pelvic lymph nodes were obtained from 105 patients at autopsy. All 105 patients had premortem serum from which prostate-specific antigen (PSA) levels were obtained. Sixty-eight did not have carcinoma of the prostate (CAP), 28 had CAP less than 1 ml and 9 had CAP larger than 1 ml. Eleven untrimmed prostates weighed 80 g or more and eight had elevated PSA levels (more than 4.0 ng/ml): five of eight without CAP, two of two with CAP less than 1 ml, and one of one with CAP larger than 1 ml. Ninety-four whole untrimmed prostates weighed less than 80 g and 20 had elevated PSA levels: ten of 60 without CAP, two of 26 with CAP less than 1 ml, and eight of eight with CAP larger than 1 ml. This study suggests that PSA levels from patients with untrimmed prostates weighing 80 g or more (equivalent to a 60-g trimmed prostate) are usually elevated regardless whether CAP is present. However, CAP less than 1 ml, in untrimmed prostates less than 80 g, usually does not elevate PSA levels whereas CAP larger than 1 ml usually does (P less than 0.0001). The likelihood that elevated PSA levels, from patients with untrimmed prostates less than 80 g, are due to CAP larger than 1 ml increases as the PSA level increases.
journal_name
Cancerjournal_title
Cancerauthors
Brawn PN,Speights VO,Kuhl D,Riggs M,Spiekerman AM,McCord RG,Coffield KS,Stewart DT,Lind MLdoi
10.1002/1097-0142(19911001)68:7<1592::aid-cncr2820subject
Has Abstractpub_date
1991-10-01 00:00:00pages
1592-9issue
7eissn
0008-543Xissn
1097-0142journal_volume
68pub_type
杂志文章相关文献
CANCER文献大全abstract:BACKGROUND:Patients with bulky laryngopharyngeal masses and a relative or absolute contraindication to general anesthesia present diagnostic difficulties. In the current study, the authors assessed the utility of transcutaneous ultrasound-guided Tru-Cut biopsy (USGTCB) under local anesthesia in such individuals. METHO...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.22679
更新日期:2007-06-01 00:00:00
abstract:BACKGROUND:Human papillomavirus (HPV) DNA has been identified in esophageal carcinomas. However, the incidence of HPV varies significantly in different geographic locations. In the current study, neoplasms from two separate geographic regions were analyzed for the presence of HPV DNA: METHODS:One hundred and ten esoph...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/(SICI)1097-0142(19960815)78:4<704::AID-CNC
更新日期:1996-08-15 00:00:00
abstract:BACKGROUND:Mantle cell lymphoma (MCL) is an incurable B-cell malignancy, and patients with this disease have the poorest prognosis among all patients with B-cell lymphomas. The signaling pathways that trigger MCL escape from immune surveillance are unclear. Because Toll-like receptors (TLRs) initiate innate and adaptiv...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.27792
更新日期:2013-02-15 00:00:00
abstract::Chromosome abnormalities from 17 malignancies that were studied using direct preparations and G-, Q-, and C-banding methods are presented and the findings assessed. The material used was from 6 primary cervical carcinomas, 5 primary and metastatic ovarian carcinomas and 6 other metastatic carcinomas. In general, chrom...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197912)44:6<2108::aid-cncr282044
更新日期:1979-12-01 00:00:00
abstract:BACKGROUND:The possible association between ovarian carcinoma and ovulation-inducing drugs has led to renewed interest in the potential carcinogenic risks of these drugs. In vitro fertilization (IVF) has been linked to multiple pregnancies and possibly congenital malformations. However, to the authors' knowledge the as...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(20000615)88:12<2845::aid-cncr26>
更新日期:2000-06-15 00:00:00
abstract:BACKGROUND:Surgery alone is the appropriate first-line treatment for patients with mesoblastic nephroma (MN). Nevertheless, there are reports of local recurrences and metastasis, especially in the cellular subtype. The authors evaluated the outcome of patients with MN who were enrolled in either the International Socie...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.21836
更新日期:2006-05-15 00:00:00
abstract:BACKGROUND:The capacity of neonatal sacrococcygeal teratomas (SCT) to recur is a well-recognized phenomenon. However, only a few studies have reported recurrence of the tumors beyond childhood. METHODS:A follow-up of patients for the detection of late recurrent SCT was performed in 45 patients, ages 4-43 years (mean, ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19931215)72:12<3727::aid-cncr282
更新日期:1993-12-15 00:00:00
abstract::A leukocyte migration procedure was utilized to test cellular hypersensitivity of breast cancer patients' leukocytes to autologous and homologous breast cancer tissues and to murine milk containing murine mammary tumor virus (MuMTV). The in vitro responsiveness of the leukocytes and the antigenicity of breast cancer t...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197501)35:1<121::aid-cncr2820350
更新日期:1975-01-01 00:00:00
abstract::Aryl hydrocarbon hydroxylase (AHH) inducibility was determined in a lymphoblast test system in 2,000 consecutive middle-aged male smokers, 304 ex-smokers, and 218 never-smokers in the same birth-year cohorts. Intraindividual, intraobserver, and interobserver, as well as temporal, reproducibility was checked in a speci...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19851015)56:8<1988::aid-cncr2820
更新日期:1985-10-15 00:00:00
abstract::Certain features of nodular sclerosing Hodgkin's disease predispose toward achievement of excellent radiotherapeutic results using clinical staging rather than currently advocated surgical staging including laparatomy. These include a distinct pattern of contiguous lymphatic involvement and the infrequent disseminatio...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197704)39:4<1439::aid-cncr282039
更新日期:1977-04-01 00:00:00
abstract:BACKGROUND:To the authors' knowledge, relatively little is known regarding the interaction of risk factors for hepatocellular carcinoma (HCC) with age, sex, and liver disorder status. METHODS:The authors followed 504,646 Korean patients aged 40 to 80 years who underwent routine health checkups between 2002 and 2003 un...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.31406
更新日期:2018-07-01 00:00:00
abstract::The authors describe the results of multimodality therapy in 27 patients with biopsy-proven primary central nervous system (CNS) lymphoma treated between 1976 and 1986. Treatment included surgical resection (15 patients), radiotherapy (27 patients), and chemotherapy (nine patients). Actuarial survival rates for the 27...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19890301)63:5<939::aid-cncr28206
更新日期:1989-03-01 00:00:00
abstract::Forty-five immunocompetent patients with solid tumors were immunized with BCG, PPD, and tumor cells. The methods were practical, but the morbidity was significant, including painful draining ulcerations at vaccine sites, possible enhancement of tumor growth in three patients, and the discovery at autopsy of systemic t...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197607)38:1<131::aid-cncr2820380
更新日期:1976-07-01 00:00:00
abstract:BACKGROUND:Exercise is a modifiable lifestyle risk factor associated with prostate cancer risk reduction. However, whether this association is different as a function of race is unclear. In the current study, the authors attempted to characterize the link between exercise and prostate cancer (CaP) in white and black Am...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.27791
更新日期:2013-04-01 00:00:00
abstract:BACKGROUND:Adenoid cystic carcinoma (ACC) of the head and neck (ACCHN) is a rare tumor of minor salivary, parotid, and submandibular glands. The biologic behavior of the disease is poorly understood, and nonsurgical treatment strategies have yet to be standardized. The long-term prognosis continues to be guarded, with ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.27408
更新日期:2012-09-15 00:00:00
abstract::A case is reported of a patient with pancreatic carcinoma who developed pancreatic ascites after intraoperative fine-needle aspiration cytology (FNAC) biopsy. This complication of FNAC has not previously been reported to the authors' knowledge. The literature is reviewed, and FNAC is shown to be the safest method of p...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19900601)65:11<2537::aid-cncr282
更新日期:1990-06-01 00:00:00
abstract:BACKGROUND:To assess whether the effectiveness of a combination of transcatheter arterial chemoembolization (TACE) and percutaneous ethanol injection (PEI) is superior to PEI alone in the treatment of patients with small hepatocellular carcinoma (HCC), a randomized controlled study was performed. METHODS:Fifty-two pat...
journal_title:Cancer
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1002/1097-0142(20010915)92:6<1516::aid-cncr1477
更新日期:2001-09-15 00:00:00
abstract::A case of osteosarcoma arising in the soft tissue of the larynx in an elderly man is presented with light and electron microscopic documentation. The patient developed chronic hoarseness and a recurring polypoid laryngeal tumor, causing acute airway obstruction. He was treated by total laryngectomy, but he died with m...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197811)42:5<2343::aid-cncr282042
更新日期:1978-11-01 00:00:00
abstract::Ninety-five malignant tumors in the submandibular gland, the sublingual gland, and the minor salivary glands seen in a 25-year period were reviewed. The patients were retrospectively staged using the Union Internationale Contre le Cancer (UICC) classification. The most frequent tumor was adenoid cystic carcinoma, foll...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19911201)68:11<2431::aid-cncr282
更新日期:1991-12-01 00:00:00
abstract::Twenty-two patients who previously responded to first-line hormonal therapy were evaluated for factors which would predict for response to second hormonal manipulation. Investigations performed at progression after initial hormone response included immunocytochemical estimation of estrogen and progesterone receptors a...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19900615)65:12<2720::aid-cncr282
更新日期:1990-06-15 00:00:00
abstract:BACKGROUND:Disseminated intravascular coagulation (DIC) and primary fibrinolysis have both been reported in association with prostate carcinoma. The correct diagnosis of the coagulopathy can be difficult and the appropriate management controversial. METHODS:A case is presented of a man in whom DIC and soft tissue hemo...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19920801)70:3<656::aid-cncr28207
更新日期:1992-08-01 00:00:00
abstract::A case of an extramedullary intrathoracic plasmacytoma causing superior vena cava syndrome is described. Review of the literature on intrathoracic plasmacytomas and superior vena cava syndrome revealed that no similar cases have been described to date. The initial presentation, management, and response to treatment ar...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/1097-0142(19910915)68:6<1376::aid-cncr2820
更新日期:1991-09-15 00:00:00
abstract:BACKGROUND:Little is known about genetic aberrations associated with development and progression of biliary tract carcinomas. METHODS:To study chromosomal aberrations associated with development and progression of biliary tract carcinomas, the authors used comparative genomic hybridization to examine 50 such carcinoma...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(20010201)91:3<570::aid-cncr1036>
更新日期:2001-02-01 00:00:00
abstract::In a retrospective review (1950-1975) of the Mayo Clinic experience with seminomas (483 cases), twelve patients (2.5%) were found to have a retroperitoneal seminoma without evidence of testicular involvement. The mean age was 47 years (range, 31-67). Eleven patients were treated by radiation alone, with doses ranging ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19820501)49:9<1934::aid-cncr2820
更新日期:1982-05-01 00:00:00
abstract:BACKGROUND:Survivors of head and neck squamous cell carcinoma (HNSCC) face excess mortality from multiple causes. METHODS:We used the population-based Surveillance, Epidemiology, and End Results (SEER) cancer registry data to evaluate the causes of death in patients with nonmetastatic HNSCC diagnosed between 1992 and ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.28588
更新日期:2014-05-15 00:00:00
abstract::The individual medical histories in the files of the Oxford Record Linkage Study for the years 1963 to 1967 were analyzed to ascertain any previously unsuspected associations between cancers of the large bowel and other diseases in individuals, and to quantify the relative risks of disorders already known to be associ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197906)43:6<2553::aid-cncr282043
更新日期:1979-06-01 00:00:00
abstract::A number of problems inherent to quality of care evaluation have been described above. Although issues such as limited resources and clinical staff resistance may not be specific to cancer care, they certainly impact on the evaluation of the quality of care offered to cancer patients. Other issues such as complexity o...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19890701)64:1+<302::aid-cncr2820
更新日期:1989-07-01 00:00:00
abstract::Twenty-four patients with metastatic cancer of the choroid were seen in the Department of Therapeutic Radiology, Rush-Presbyterian--St. Luke's Medical Center, Chicago, between 1964 and 1975. One fourth of the patients had involvement in both eyes, for a total of 30 eyes involved with metastatic cancer. The most common...
journal_title:Cancer
pub_type: 杂志文章
doi:
更新日期:1981-02-15 00:00:00
abstract::Oral submucous fibrosis (OSF) is a chronic disease of the oral mucosa characterized by inflammation and a progressive fibrosis of the lamina propria and deeper connective tissues. It is a condition predominantly seen among people of Indian origin, and an epidemiologic survey done a decade ago showed no less than 250,0...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/1097-0142(19920415)69:8<2011::aid-cncr2820
更新日期:1992-04-15 00:00:00
abstract::Ninety-five patients with non-oat cell lung cancer underwent resection of all apparent disease and were followed for a minimum of 36 months. Incidence of recurrence was 34% in 47 patients with N0 disease, 65% in 32 patients with N1 disease, and 81.3% in 16 patients with N2 disease (P less than 0.02 and P less than 0.0...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19860201)57:3<471::aid-cncr28205
更新日期:1986-02-01 00:00:00