Racial differences in colorectal cancer survival in the Detroit Metropolitan Area.

abstract：BACKGROUND:To the authors' knowledge, comprehensive human pathologic investigations that explore fundamental radiosurgical effects on metastatic brain tumors are sparse in the literature. The objective of this study was to analyze histopathologic findings in a set of clinically recurrent cerebral metastases after patie...

journal_title：Cancer

authors： Szeifert GT,Atteberry DS,Kondziolka D,Levivier M,Lunsford LD

更新日期：2006-06-15 00:00:00

abstract：:Histopathologic and Ki-67-staining features of cancer cells were investigated in biopsy specimens before and during radiation therapy in 29 patients with cervical squamous cell carcinoma. No morphologic changes were observed up to doses of 540 cGy. A few intact cancer cells remained up to doses of 2700 cGy. Moderate c...

journal_title：Cancer

authors： Nakano T,Oka K

更新日期：1991-08-01 00:00:00

abstract：:POEMS syndrome is a rare multisystem affliction known for its signs, from which it also takes its acronym name "peripheral neuropathy, organomegaly, endocrinopathy, monoclonal (M) protein, and skin lesions." Our study chronicles the course of this syndrome in a young woman with Castleman's disease (angiofollicular lym...

journal_title：Cancer

authors： Mandler RN,Kerrigan DP,Smart J,Kuis W,Villiger P,Lotz M

更新日期：1992-06-01 00:00:00

abstract：:Twenty of 391 newly diagnosed cases of prostatic cancer (5%) had a prior prostatectomy for benign disease. Digital rectal examination in 16 of 19 patients (84%) revealed a significant prostatic abnormality. Continued serial digital rectal examination should be performed routinely after prostatectomy for benign disease...

journal_title：Cancer

authors： Schwartz I,Wein AJ,Malloy TR,Glick JH

更新日期：1986-08-15 00:00:00

abstract：:Utah cancer mortality for the years 1950-1969 and morbidity for the years 1966-1970 are reported. Utah had 18% fewer cases of cancer than expected based on the Third National Cancer Survey, and 24% fewer cancer deaths than expected based on national mortality data. Cancer sites associated with cigarette smoking and al...

journal_title：Cancer

authors： Lyon JL,Gardner JW,Klauber MR,Smart CR

更新日期：1977-06-01 00:00:00

abstract：BACKGROUND:The results of a Phase II study of concurrent chemotherapy and accelerated fractionation radiation therapy followed by surgical resection for patients with both adenocarcinoma and squamous cell carcinoma of the esophagus are presented. Pretreatment and postinduction staging were correlated with pathologic fi...

journal_title：Cancer

authors： Adelstein DJ,Rice TW,Becker M,Larto MA,Kirby TJ,Koka A,Tefft M,Zuccaro G

更新日期：1997-09-15 00:00:00

abstract：:The feasibility of employing adjuvant topical mechlorethamine after electron beam therapy in the treatment of patients with mycosis fungoides is demonstrated. Patients treated with a planned adjuvant topical mechlorethamine schedule had a median disease-free interval of 25 months compared to 17 months for the group tr...

journal_title：Cancer

authors： Price NM,Hoppe RT,Constantine VS,Fuks ZY,Farber EM

更新日期：1977-12-01 00:00:00

abstract：:The records of 52 patients younger than 40 years of age who had bronchogenic carcinoma diagnosed between 1965 and 1985 were reviewed. The preponderance of adenocarcinoma (54%), the lower male-female ratio in this age group compared with patients age 40 or older (2:1), the importance of cigarette smoking as a causative...

journal_title：Cancer

authors： Jubelirer SJ,Wilson RA

更新日期：1991-03-01 00:00:00

abstract：:The myeloproliferative neoplasms (MPNs) essential thrombocythemia (ET), polycythemia vera (PV), and primary myelofibrosis (MF) are malignancies that frequently harbor the recurrent somatic point mutation JAK2(V617F). The discovery of this mutation has fueled the development of Janus kinase 2 (JAK2) inhibitors. Availab...

journal_title：Cancer

authors： Quintás-Cardama A,Verstovsek S

更新日期：2012-02-15 00:00:00

abstract：BACKGROUND:For the moment, there is uncertainty about the usefulness of early treatment of localized prostate carcinoma, uncertainty about whether some patients with early cancer can be managed expectantly, and uncertainty about how such patients might be recognized. METHODS:The authors studied serial values of prosta...

journal_title：Cancer

authors： Vollmer RT,Egawa S,Kuwao S,Baba S

更新日期：2002-03-15 00:00:00

abstract：:Review of the consultation records of the Gastrointestinal Surgical Oncology service at Roswell Park Memorial Institute from 1982 to 1987 revealed 22 patients with a clinical diagnosis of neutropenic enterocolitis. Ninety-one percent of the patients had hematologic malignancies, and 95% were receiving cytotoxic chemot...

journal_title：Cancer

authors： Wade DS,Nava HR,Douglass HO Jr

更新日期：1992-01-01 00:00:00

abstract：:Although cancer often is referred to as "a disease of the genes," it is indisputable that the (epi)genetic properties of individual cancer cells are highly variable, even within the same tumor. Hence, preexisting resistant clones will emerge and proliferate after therapeutic selection that targets sensitive clones. He...

journal_title：Cancer

authors： Napel S,Mu W,Jardim-Perassi BV,Aerts HJWL,Gillies RJ

更新日期：2018-12-15 00:00:00

abstract：:Fifteen malignant schwannomas were examined by light and electron microscopy. Five tumors arose in patients with neurofibromatosis and five were contiguous with a peripheral nerve (Group I). Five tumors met neither of these generally accepted diagnostic criteria but were light microscopically seen as compatible with m...

journal_title：Cancer

authors： Taxy JB,Battifora H,Trujillo Y,Dorfman HD

更新日期：1981-09-15 00:00:00

abstract：:This review presents our experience with the use of estrogen receptors (ER) and progesterone receptors (PgR) in the prediction of response to endocrine therapy in stage IV breast cancer. Presence of ER (> 3 fmol/mg cytosol protein) significantly predicted response to the antiestrogen tamoxifen and to hypophysectomy. E...

journal_title：Cancer

authors： Manni A,Arafah B,Pearson OH

更新日期：1980-12-15 00:00:00

abstract：BACKGROUND:The specific activity of the non-receptor protein tyrosine kinase, Src, is increased in the majority of colon and rectal adenocarcinomas compared to normal mucosa. However, the prognostic significance of this difference is unknown. The objective of the current study was to determine if Src activity is a mark...

journal_title：Cancer

authors： Aligayer H,Boyd DD,Heiss MM,Abdalla EK,Curley SA,Gallick GE

更新日期：2002-01-15 00:00:00

abstract：:A new method of arterially administering an oily anticancer agent was successfully established for the selective targeting of metastatic lymph nodes. A high molecular weight anticancer agent, a conjugate of copolymer (styrene maleic acid) to neocarzinostatin (SMANCS) was prepared in our laboratory and dissolved in a l...

journal_title：Cancer

authors： Ohtsuka N,Konno T,Miyauchi Y,Maeda H

更新日期：1987-05-01 00:00:00

abstract：:Twelve cases of ovarian adenocarcinoma were studied for alterations in proto-oncogenes, and a unique pattern of altered ras proto-oncogenes was observed. Amplification of ras-Ki was found in three of seven ovarian tumors and amplification of ras-Ha in one of 12. In contrast, ras-Ha amplification was not found in any o...

journal_title：Cancer

authors： Zhou DJ,Gonzalez-Cadavid N,Ahuja H,Battifora H,Moore GE,Cline MJ

更新日期：1988-10-15 00:00:00

abstract：BACKGROUND:Although systemic therapy for metastatic breast cancer (MBC) continues to evolve, there are scant data to guide physicians and patients when symptoms develop. In this article, the authors report the frequency and durability of palliative procedures performed in the setting of MBC. METHODS:From July 2002 to ...

journal_title：Cancer

authors： Morrogh M,Miner TJ,Park A,Jenckes A,Gonen M,Seidman A,Morrow M,Jaques DP,King TA

更新日期：2010-07-15 00:00:00

abstract：:The results of nine US multicenter, sequential crossover, dose titration studies of controlled-release oral morphine (MS Contin 30 mg tablets [MSC], Purdue Frederick, Norwalk, CT) are reviewed in Part I. The studies demonstrated the prolonged analgesic efficacy of the preparation in the treatment of patients with mode...

journal_title：Cancer

authors： Kaiko RF,Grandy RP,Oshlack B,Pav J,Horodniak J,Thomas G,Ingber E,Goldenheim PD

更新日期：1989-06-01 00:00:00

abstract：BACKGROUND:Specialty of the endoscopist has been related to the postcolonoscopy interval risk of colorectal cancer (CRC). However, the impact of such a difference on the long-term CRC prevention rate by screening colonoscopy is largely unknown. METHODS:A Markov model was constructed to simulate the efficacy and cost o...

journal_title：Cancer

authors： Hassan C,Rex DK,Zullo A,Cooper GS

更新日期：2012-09-15 00:00:00

abstract：:A study of 112 biopsy specimens from Danish oral leukoplakia patients and 145 biopsy specimens from Indian leukoplakia patients revealed a chevron-like keratinization of the epithelium in a number of cases. Clinically, this type of keratinization was often characterized by a pumice-like appearance. The clinical and hi...

journal_title：Cancer

authors： Pindborg JJ,Reibel J,Roed-Peterson B,Mehta FS

更新日期：1980-05-01 00:00:00

abstract：BACKGROUND:The authors analyzed the secretion of extracellular matrix-degrading proteinases, including urinary-type plasminogen activator (u-PA), matrix metalloproteinase-2 (MMP-2, gelatinase A), and MMP-9 (gelatinase B), by short term primary cultures of epithelial ovarian carcinoma cells derived from primary ovarian ...

journal_title：Cancer

authors： Fishman DA,Bafetti LM,Banionis S,Kearns AS,Chilukuri K,Stack MS

更新日期：1997-10-15 00:00:00

abstract：:Treatment with BCG (Bacillus Calmette-Guérin) followed by irradiation was attempted to improve response to therapy by cutaneous metastases from malignant skin melanomas. Both agents were applied in low doses, known to cause minimal side effects. Nineteen patients, divided into three groups, entered the clinical trial....

journal_title：Cancer

authors： Plesnicar S,Rudolf Z

更新日期：1982-09-15 00:00:00

abstract：BACKGROUND:The measurement of estrogen receptors (ER) in breast cancer specimens has traditionally been assessed with a dextran-coated charcoal assay (DCCA). More recently the immunohistochemical staining (IHC) method has gained increasing popularity because of its ability to use fixed tissue, assess needle biopsies, a...

journal_title：Cancer

authors： Alberts SR,Ingle JN,Roche PR,Cha SS,Wold LE,Farr GH Jr,Krook JE,Wieand HS

更新日期：1996-08-15 00:00:00

abstract：:This paper discusses the imaging methods available for the detection and diagnosis of colon cancer, concentrating on endoscopy and barium radiology. Effective utilization of these two methods may be facilitated by using flexible sigmoidoscopy to direct further investigation. There is a need for educational efforts to ...

journal_title：Cancer

authors： Stevenson GW

更新日期：1993-06-15 00:00:00

abstract：BACKGROUND:Although axillary lymph node metastasis is one of the most important prognostic determinants of breast carcinoma prognoses, the reasons why tumors vary in their capability to produce for axillary metastases remain unclear. METHODS:The authors used data from the nationwide Patient Care Evaluation (PCE) surve...

journal_title：Cancer

authors： Gann PH,Colilla SA,Gapstur SM,Winchester DJ,Winchester DP

更新日期：1999-10-15 00:00:00

abstract：BACKGROUND:Breast carcinoma commonly metastasizes to the skeleton in patients with advanced disease to cause bone destruction and the associated pain, hypercalcemia, fracture, and nerve-compression syndromes. In this scenario, the bone destruction is mediated by the osteoclast. Tumor-produced parathyroid hormone-relate...

journal_title：Cancer

authors： Guise TA

更新日期：2000-06-15 00:00:00

abstract：BACKGROUND:Retrospective studies suggest that dose intensity is an important determinant of outcome in the treatment of patients with a variety of malignant diseases such as breast cancer, ovarian cancer, and lymphoma. Unfortunately, these results have not been clearly substantiated in prospective randomized trials. On...

journal_title：Cancer

authors： Long GD,Negrin RS,Hoyle CF,Kusnierz-Glaz CR,Schriber JR,Blume KG,Chao NJ

更新日期：1995-09-01 00:00:00

abstract：:Using a silver staining technique, nucleolar organizer region-associated proteins (Ag-NOR) were studied in paraffin sections of five specimens of normal bronchial epithelium, eight of atypical squamous metaplasia, five of carcinoma in situ, and seven of microinvasive squamous cell carcinoma. The mean number of Ag-NOR ...

journal_title：Cancer

authors： Abe S,Ogura S,Kunikane H,Suko N,Watanabe N,Nakajima I,Kawakami Y,Inoue K

更新日期：1991-01-15 00:00:00

abstract：BACKGROUND:Two-thirds of cancer cases are associated with two lifestyle practices: 35% with the typical American diet, and 30% with tobacco use. In contrast to the field of tobacco control, research and resources dedicated to the field of nutrition have been limited, in part because dietary change has been considered c...

journal_title：Cancer

authors： Bal DG,Foerster SB

更新日期：1993-08-01 00:00:00