Prophylaxis in ovarian cancer.

abstract：BACKGROUND:The axon guidance cue molecule Slit2 has been shown to suppress cancer cell invasion. However, the role of Slit2 in growth inhibition is still controversial. The authors identified a novel exon 15 (AKEQYFIP)-deleted slit2, located at the end of the second leucine-rich repeat (LRR2). Because LRR2 interacts wi...

journal_title：Cancer

authors： Lin YY,Yang CH,Sheu GT,Huang CY,Wu YC,Chuang SM,Fann MJ,Chang H,Lee H,Chang JT

更新日期：2011-08-01 00:00:00

abstract：:Fever, clinical infection, bacteriologically documented infection, and death from infection were evaluated in 95 consecutive uninfected patients with severe granulocytopenia (less than 0.5 x 10(6)/liter). Patients were randomly allocated to reverse isolation and prophylactic oral nonabsorbable antibiotics or to open w...

journal_title：Cancer

authors： Ribas-Mundo M,Granena A,Rozman C

更新日期：1981-07-15 00:00:00

abstract：:In the evaluation of cervical cancer, computed tomography (CT) is used primarily to stage advanced tumors and evaluate for recurrence. Because of reports that CT imaging lacks sensitivity and specificity in the detection of primary tumors and metastatic lesions, its use in these applications has been limited, but rece...

journal_title：Cancer

authors： Pannu HK,Fishman EK

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:The difficulties adolescents and young adults (AYAs) encounter during a cancer experience may result in a reduction in or absence of empowerment. The aims of the current study were to assess levels of empowerment and associated (demographic, clinical, or psychological) factors and examine the association bet...

journal_title：Cancer

authors： Kaal SEJ,Husson O,van Duivenboden S,Jansen R,Manten-Horst E,Servaes P,Prins JB,van den Berg SW,van der Graaf WTA

更新日期：2017-10-15 00:00:00

abstract：BACKGROUND:African-American (AA) women have lower survival rates from cervical cancer compared with white women. The objective of this study was to examine the influence of socioeconomic status (SES) and other variables on racial disparities in overall survival among women with invasive cervical cancer. METHODS:One th...

journal_title：Cancer

authors： Movva S,Noone AM,Banerjee M,Patel DA,Schwartz K,Yee CL,Simon MS

更新日期：2008-03-15 00:00:00

abstract：BACKGROUND:The availability of Ki-67 monoclonal antibody has opened new possibilities for an extensive analysis of cell kinetics in human neoplasms. Ki-67 antibody reveals a nuclear antigen that is expressed in proliferating but not in quiescent cells. Although the reliability of Ki-67 immunostaining has been evaluated...

journal_title：Cancer

authors： Scotlandi K,Serra M,Manara MC,Maurici D,Benini S,Nini G,Campanacci M,Baldini N

更新日期：1995-02-01 00:00:00

abstract：:The physiologic consequences of malnutrition in children with cancer are reviewed. It is stressed that the child with cancer has a nutritional state that is no different from the average population from which the child comes. What little malnutrition is seen is calorie malnutrition. The physiologic consequences are th...

journal_title：Cancer

authors： van Eys J

更新日期：1986-10-15 00:00:00

abstract：:Ninety-five patients with non-oat cell lung cancer underwent resection of all apparent disease and were followed for a minimum of 36 months. Incidence of recurrence was 34% in 47 patients with N0 disease, 65% in 32 patients with N1 disease, and 81.3% in 16 patients with N2 disease (P less than 0.02 and P less than 0.0...

journal_title：Cancer

authors： Iascone C,DeMeester TR,Albertucci M,Little AG,Golomb HM

更新日期：1986-02-01 00:00:00

abstract：BACKGROUND:The objective of this study was to determine the potential economic implications resulting from using exemestane (EXE), a new steroidal, irreversible aromatase inactivator, compared with megestrol acetate (MA) in patients with advanced breast carcinoma. METHODS:The model used the clinical results from the m...

journal_title：Cancer

authors： Hillner BE,Radice D

更新日期：2001-02-01 00:00:00

abstract：BACKGROUND:Colorectal cancer (CRC) develops through the alteration of several critical pathways. This study was aimed at evaluating the influence of critical pathways on survival outcomes for patients with CRC. METHODS:Targeted next-generation sequencing of 40 genes included in the 5 critical pathways of CRC (WNT, P53...

journal_title：Cancer

authors： Lee DW,Han SW,Cha Y,Bae JM,Kim HP,Lyu J,Han H,Kim H,Jang H,Bang D,Huh I,Park T,Won JK,Jeong SY,Park KJ,Kang GH,Kim TY

更新日期：2017-09-15 00:00:00

abstract：BACKGROUND:The purpose of this study was to evaluate the results of thyroid fine-needle aspiration (FNA) and to determine the reasons for the discrepancies between the cytologic and histologic diagnoses. METHODS:The authors evaluated the cytologic and histologic results of 133 FNAs obtained from 92 patients who underw...

journal_title：Cancer

authors： Sidawy MK,Del Vecchio DM,Knoll SM

更新日期：1997-08-25 00:00:00

abstract：:An astroblastoma in the cerebrum was investigated with the electron microscope. A distinctive feature of the tumor was the radial arrangement of astrocytic cells around the blood vessels. The blood vessels in the tumor commonly exhibited fenestrated endothelial cells. The endothelium was generally surrounded by lamell...

journal_title：Cancer

authors： Kubota T,Hirano A,Sato K,Yamamoto S

更新日期：1985-02-15 00:00:00

abstract：:The long-term cancer specific survival based on individual follow-up and analysis of prospectively collected data from 1061 patients undergoing resection for carcinoma of the rectum is presented. All patients were operated on and managed by one surgeon. Survival data for 978 cases were analyzed according to the method...

journal_title：Cancer

authors： Pihl E,Hughes ES,McDermott FT,Milne BJ,Korner JM,Price AB

更新日期：1980-06-01 00:00:00

abstract：:Spindle cell lipoma is a specific type of lipoma that is easily mistaken for a liposarcoma. An analysis of 114 cases of this tumor from the files of the Armed Forces Institute of Pathology reveals that is occurs chiefly in male patients between 45 and 70 years of age and affects the regions of the shoulder and posteri...

journal_title：Cancer

authors： Enzinger FM,Harvey DA

更新日期：1975-11-01 00:00:00

abstract：:To determine the efficacy of adjuvant chemotherapy in patients with advanced head and neck squamous carcinoma, the National Cancer Institute initiated a multi-institutional, prospective randomized trial termed the Head and Neck Contracts Program. Between 1978 and 1982, 462 patients with resectable Stage III or IV canc...

journal_title：Cancer

authors：

更新日期：1987-08-01 00:00:00

abstract：:The establishment and characterization of 11 human lung cancer cell lines are described in this article. Nine of these cell lines were established over a 5-year period, from 1983 to 1988, from patients treated at the Kingston Regional Cancer Centre. These include eight definite or probable small cell lung cancer (SCLC...

journal_title：Cancer

authors： Campling BG,Haworth AC,Baker HM,Greer DL,Holden JJ,Bradley EC,Pym J,Dexter DF

更新日期：1992-04-15 00:00:00

abstract：BACKGROUND:In the current study, the authors propose the quantitative Gleason score (qGS), a modification of the current Gleason grading system for prostate cancer, based on the weighted average of Gleason patterns present in the pathology specimen. They hypothesize that the qGS can improve prostate cancer risk stratif...

journal_title：Cancer

authors： Reese AC,Cowan JE,Brajtbord JS,Harris CR,Carroll PR,Cooperberg MR

更新日期：2012-12-15 00:00:00

abstract：BACKGROUND:Mycosis fungoides (MF) is predominantly a disease of older patients, but occasionally occurs in children. The aims of the current study were to describe the clinical presentation, pathologic features, and disease progression (DP) in patients who developed MF before age 16 years. METHODS:A retrospective stud...

journal_title：Cancer

authors： Wain EM,Orchard GE,Whittaker SJ,Spittle M Sc MF,Russell-Jones R

更新日期：2003-11-15 00:00:00

abstract：BACKGROUND:Achieving a pathologic complete response (pCR) with neoadjuvant chemotherapy (NAC) in patients with muscle-invasive bladder cancer (MIBC) has been associated with improved overall survival (OS). This study was aimed at evaluating the impact of pathologic downstaging (pDS; ie, a pT stage at least 1 stage lowe...

journal_title：Cancer

authors： Martini A,Jia R,Ferket BS,Waingankar N,Plimack ER,Crabb SJ,Harshman LC,Yu EY,Powles T,Rosenberg JE,Pal SK,Vaishampayan UN,Necchi A,Wiklund NP,Mehrazin R,Mazumdar M,Sfakianos JP,Galsky MD

更新日期：2019-09-15 00:00:00

abstract：:Thirty-one patients were treated with cisplatin combination chemotherapy for advanced seminoma (26 Stage III or bulky Stage II testicular, and five disseminated extragonadal). Seventeen (89%) of 19 patients not previously pretreated and four (80%) of five who had received only abdominal irradiation entered continuous ...

journal_title：Cancer

authors： Pizzocaro G,Salvioni R,Piva L,Zanoni F,Milani A,Faustini M

更新日期：1986-10-15 00:00:00

abstract：BACKGROUND:Modified nucleosides such as 1-methyl-adenosine and pseudouridine exist as minute components of transfer ribonucleic acid (tRNA) and are excreted in the urine in large amounts in the presence of malignancy. Although use of these modified nucleosides as tumor markers has long been studied and many reports hav...

journal_title：Cancer

authors： Masuda M,Nishihira T,Itoh K,Mizugaki M,Ishida N,Mori S

更新日期：1993-12-15 00:00:00

abstract：:Nine children with acute promyelocytic leukemia (APL) are presented. This series of children represents 7% of all acute leukemias and 21% of acute myelogenous leukemias seen during the same period at the Red Cross War Memorial Children's Hospital. These figures are much higher than the incidence quoted in other series...

journal_title：Cancer

authors： Gilbert RD,Karabus CD,Mills AE

更新日期：1987-03-01 00:00:00

abstract：:Seventeen patients were given DTIC, 200 mg/m2/day in five-day courses every four to six weeks. In four patients (stage II) treated on an adjuvant basis, tumor recurrence has been verified in three. Four of the palliatively treated patients were also given DTIC by regional intra-arterial infusion with minimal positive ...

journal_title：Cancer

authors： Jönsson PE,Agrup G,Arnbjörnsson E,Hafström L,Rorsman H

更新日期：1980-01-15 00:00:00

abstract：BACKGROUND:Evidence of racial disparities in the receipt of postmastectomy breast reconstruction is well documented. The objective of this study was to describe trends in racial disparities overall and by reconstructive technique. METHODS:The American College of Surgeons National Surgical Quality Improvement Program d...

journal_title：Cancer

authors： Epstein S,Tran BN,Cohen JB,Lin SJ,Singhal D,Lee BT

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:A crossover in breast carcinoma incidence at ages 45-49 years has been observed between black and white women, with blacks experiencing higher incidence at younger ages and lower incidence after age 50 years. Can this phenomenon be partially explained by the differences in the distributions of reproductive r...

journal_title：Cancer

authors： Pathak DR,Osuch JR,He J

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND:Tyrosine kinase inhibitors (TKIs) have improved the outcome of patients with gastrointestinal stromal tumors (GISTs), but most patients eventually develop resistance and progress. Dasatinib is a potent inhibitor of BCR-ABL, KIT, and SRC family kinases as well as imatinib-resistant cells. In GISTs, response e...

journal_title：Cancer

authors： Montemurro M,Cioffi A,Dômont J,Rutkowski P,Roth AD,von Moos R,Inauen R,Toulmonde M,Burkhard RO,Knuesli C,Bauer S,Cassier P,Schwarb H,Le Cesne A,Koeberle D,Bärtschi D,Dietrich D,Biaggi C,Prior J,Leyvraz S

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:Insulin receptor (IR), a member of the receptor tyrosine kinase family, is expressed in normal thyroid cells and affects thyroid cell proliferation and differentiation. METHODS:The authors measured IR content in benign and malignant thyroid tumors by three independent methods: a specific radioimmunoassay, 1...

journal_title：Cancer

authors： Frittitta L,Sciacca L,Catalfamo R,Ippolito A,Gangemi P,Pezzino V,Filetti S,Vigneri R

更新日期：1999-01-15 00:00:00

abstract：:The yield of additional information from anteroposterior full-lung tomograms that changed stage or treatment, in comparison to that obtained from routine chest radiographs, was prospectively evaluated in 243 previously untreated patients with Hodgkin's disease and non-Hodgkin's lymphoma. Although new information was f...

journal_title：Cancer

authors： Castellino RA,Filly R,Blank N

更新日期：1976-09-01 00:00:00

abstract：BACKGROUND:Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is the only treatment with a curative potential for myelodysplastic syndrome (MDS) patients. Allo-HSCT has substantial risks, particularly in the elderly, and its role for older MDS patients has yet to be defined. METHODS:We analyzed 88 MDS pati...

journal_title：Cancer

authors： Yucel OK,Saliba RM,Rondon G,Ahmed S,Alousi A,Bashir Q,Ciurea SO,Popat U,Khouri I,Marin D,Rezvani K,Kebriaei P,Shpall EJ,Champlin RE,Oran B

更新日期：2017-07-15 00:00:00

abstract：:Few studies have incorporated high-dose methotrexate (MTX) with leucovorin rescue in the treatment of small cell lung cancer (SCLC). Potentially therapeutic levels of MTX can be achieved in the central nervous system (CNS) by systemic administration of high doses of this drug. Utilizing a combination chemotherapy prog...

journal_title：Cancer

authors： Neijstrom ES,Capizzi RL,Rudnick SA,Kirsch M,Delaney D,Kahn L,Lipper S,Carney C

更新日期：1983-03-15 00:00:00