Postirradiation mixed müllerian tumors of the uterus: a comparative clinicopathologic study.

Abstract:

:Nine patients with mixed müllerian tumors (MMT) of the uterus associated with a history of prior pelvic irradiation were compared clinically and pathologically with 8 nonirradiation-associated MMT control patients. Patients with postirradiation tumors presented at a younger age and with symptoms indicative of extensive intraabdominal disease while the nonirradiation-associated control patients were initially evaluated for abnormal uterine bleeding only. Two-thirds of the postirradiation patient's neoplasms were classified as heterologous MMT (mixed mesodermal tumor) whereas 62% of the control patient's neoplasms were homologous MMT (carcinosarcoma). Regardless of clinical presentation or histologic composition both groups fared equally poorly with average survival times of six and seven months, respectively. We were unable to substantiate that some histologic components of uterine MMT denote a poorer prognosis than others or that the postirradiation MMT behaves any differently, in the course of time, from the sporadic type. When uterine MTT is encountered in a patient under 55 years of age, the possibility that pelvic irradiation was administered some years before should be raised.

journal_name

Cancer

journal_title

Cancer

authors

Varela-Duran J,Nochomovitz LE,Prem KA,Dehner LP

doi

10.1002/1097-0142(19800401)45:7<1625::aid-cncr2820

subject

Has Abstract

pub_date

1980-04-01 00:00:00

pages

1625-31

issue

7

eissn

0008-543X

issn

1097-0142

journal_volume

45

pub_type

杂志文章

相关文献

CANCER文献大全
  • What is the etiology of human brain tumors? A report on the first Lebow conference.

    abstract::Although the conference could not provide a definitive etiologic explanation for the observed increase in incidence of human brain tumors, particularly among the elderly, nevertheless, this interdisciplinary gathering of prominent scientists and clinicians proved invaluable in identifying new avenues of research. Clea...

    journal_title:Cancer

    pub_type:

    doi:10.1002/1097-0142(19950815)76:4<709::aid-cncr28207

    authors: Brem S,Rozental JM,Moskal JR

    更新日期:1995-08-15 00:00:00

  • Phase II trial of intermediate dose methotrexate in combination with vinblastine, doxorubicin, and cisplatin in patients with unresectable or metastatic transitional cell carcinoma.

    abstract:BACKGROUND:This study was undertaken to determine whether the use of intermediate dose methotrexate in combination with vinblastine, doxorubicin, and cisplatin as first-line therapy increases the proportion of major responders and overall survival in patients with unresectable or metastatic transitional cell carcinoma ...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章

    doi:10.1002/(sici)1097-0142(19990301)85:5<1145::aid-cn

    authors: Dodd PM,McCaffrey JA,Mazumdar M,Scher H,Vlamis V,Higgins G,Herr H,Bajorin DF

    更新日期:1999-03-01 00:00:00

  • Human monoclonal antibodies derived from lymph nodes of a patient with breast carcinoma react with MuMTV polypeptides.

    abstract::Nine human hybridoma cell lines were established from a fusion of axillary lymph node lymphocytes of a patient with breast ductal carcinoma with a human lymphoblastoid cell line. The human hybridoma nature of the fusion products was confirmed by chromosomal analysis and HLA typing. The hybridomas are stable over a yea...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19870101)59:1<43::aid-cncr282059

    authors: Shoenfeld Y,Hizi A,Tal R,Smorodinsky NI,Lavie G,Mor C,Schteren S,Mammon Z,Pinkhas J,Keydar T

    更新日期:1987-01-01 00:00:00

  • Intrapulmonary presentation of extraskeletal myxoid chondrosarcoma of the extremity. Report of two cases.

    abstract::Two cases of extraskeletal myxoid chondrosarcoma are reported. The patients presented with metastasis to the lung, 10 years and 2 years, respectively, prior to discovery of the primary neoplasms in the soft tissues of the lower extremities. ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19860901)58:5<1144::aid-cncr2820

    authors: D'Ambrosio FG,Shiu MH,Brennan MF

    更新日期:1986-09-01 00:00:00

  • Thyroid fine-needle aspiration with atypia of undetermined significance: a necessary or optional category?

    abstract:BACKGROUND:Atypia of undetermined significance is a controversial category in thyroid fine-needle aspiration (FNA), not only for its questioned clinical utility, but also for its very existence as an expression of uncertainty. The current study was performed to investigate the potential impact of eliminating this categ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncy.20039

    authors: Shi Y,Ding X,Klein M,Sugrue C,Matano S,Edelman M,Wasserman P

    更新日期:2009-10-25 00:00:00

  • Bone scanning in patients with early breast carcinoma: should it be a routine staging procedure?

    abstract::Bone scanning is a sensitive test for the detection of metastatic breast cancer, but not all abnormal findings on bone scan are diagnostic of skeletal metastasis. Recent studies have found a relatively low rate (less than or equal to 5%) of abnormal scans in patients with Stage I and II breast cancers, and only half o...

    journal_title:Cancer

    pub_type: 杂志文章,评审

    doi:10.1002/1097-0142(19810201)47:3<486::aid-cncr28204

    authors: Lee YT

    更新日期:1981-02-01 00:00:00

  • The effects of postoperative adjuvant chemotherapy and radiotherapy on testicular function in men undergoing treatment for soft tissue sarcoma.

    abstract::Testicular function was studied in 26 men with sarcoma who received adjuvant treatment with doxorubicin, cyclophosphamide, and high-dose methotrexate (with or without radiotherapy). Testicular size, sperm output, and serum FSH, LH and testosterone levels were assessed after treatment. Five of 17 men who received chemo...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19810515)47:10<2368::aid-cncr282

    authors: Shamberger RC,Sherins RJ,Rosenberg SA

    更新日期:1981-05-15 00:00:00

  • Lymphangiography in patients with ovarian epithelial cancer: an evaluation of 289 consecutive cases.

    abstract::From January, 1973, to June, 1976, 226 patients with palpable ovarian masses were evaluated preoperatively by lymphography. Histology showed 166 cases of malignant epithelial tumors, 26 benign tumors, and 34 malignant special tumors (not included in this report). Furthermore, the group of patients included 99 recurren...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197710)40:4<1444::aid-cncr282040

    authors: Musumeci R,Banfi A,Bolis G,Candiani GB,De Palo G,Di Re F,Lucina L,Lattuada A,Mangioni C,Mattioli G,Natale N

    更新日期:1977-10-01 00:00:00

  • Perineural invasion of prostate carcinoma cells is associated with reduced apoptotic index.

    abstract:BACKGROUND:Prostate carcinoma is often associated with perineural (PN) invasion. The common occurrence of this phenomenon has led to speculation regarding the mechanisms of this association, yet to date there have been no studies that clearly define biologic differences between PN and nonperineural (NPN) carcinoma cell...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/(SICI)1097-0142(19960915)78:6<1267::AID-CN

    authors: Yang G,Wheeler TM,Kattan MW,Scardino PT,Thompson TC

    更新日期:1996-09-15 00:00:00

  • Flow cytometry of low stage bladder tumors: correlation with cytologic and cystoscopic diagnosis.

    abstract::Flow cytometry examinations (FCM) were carried out on 110 bladder irrigation specimens from 84 urologic outpatients who had had prior conservative treatment for low stage bladder tumors. The specimens were easily obtained, and adequately cellular in all cases. Of 60 examinations on patients with no cytoscopic abnormal...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19820101)49:1<109::aid-cncr28204

    authors: Devonec M,Darzynkiewicz Z,Kostyrka-Claps ML,Collste L,Whitmore WF Jr,Melamed MR

    更新日期:1982-01-01 00:00:00

  • Application of laser capture microdissection to cytologic specimens for the detection of immunoglobulin heavy chain gene rearrangement in patients with malignant lymphoma.

    abstract:BACKGROUND:The demonstration of the monoclonality of immunoglobulin heavy chain (IgH) gene rearrangement is an indispensable method for the diagnosis of B-cell lymphoma as well as histocytochemical analysis. For the detection of IgH gene rearrangement, the extraction of DNA from a homogenous cell population is necessar...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章

    doi:10.1002/cncr.11331

    authors: Orba Y,Tanaka S,Nishihara H,Kawamura N,Itoh T,Shimizu M,Sawa H,Nagashima K

    更新日期:2003-08-25 00:00:00

  • Carcinoma detection at the breast examination center of Harlem.

    abstract:BACKGROUND:Breast carcinoma is one of the leading causes of excess mortality rates in Harlem, an inner-city neighborhood with the highest mortality rates and worst life expectancy in New York City. This study reports the results of a breast carcinoma screening and diagnostic program in Harlem. METHODS:Retrospective re...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.10640

    authors: Liberman L,Freeman HP,Chandra S,Stein AL,McCord C,Godfrey D,Dershaw DD

    更新日期:2002-07-01 00:00:00

  • Trioxifene mesylate in the treatment of advanced breast cancer.

    abstract::The efficacy of trioxifene mesylate, a new antiestrogen, in the management of advanced breast cancer was evaluated in 69 patients. Fifty-two patients were randomly allocated to dose schedules of 5 mg, 10 mg, and 20 mg orally twice daily. There were five complete responders (10%), 22 partial responders (42%), and 9 pat...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1002/1097-0142(19860101)57:1<40::aid-cncr282057

    authors: Lee RW,Buzdar AU,Blumenschein GR,Hortobagyi GN

    更新日期:1986-01-01 00:00:00

  • Acute pancreatitis associated with continuous infusion cytarabine therapy: a case report.

    abstract:BACKGROUND:While acute pancreatitis is a recognized complication of numerous drugs, cytarabine's role in causing this complication is controversial. Approximately 15 cases have been reported to the Food and Drug Administration linking cytarabine with pancreas-related toxicities. Previous case reports have been complica...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/(SICI)1097-0142(19960615)77:12<2588::AID-C

    authors: McBride CE,Yavorski RT,Moses FM,Robson ME,Solimando DA Jr,Byrd JC

    更新日期:1996-06-15 00:00:00

  • Histogenesis of spontaneous regression of cervical intraepithelial neoplasias.

    abstract::It is justifiable to assume that a spontaneous regression of cervical intraepithelial neoplasia is in progress when pathologic epithelium is replaced by normal epithelium. Very rare histologic pictures of this process are shown. Dysplastic squamous epithelium or intraepithelial carcinomas become detached from their ba...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(1984)54:4<616::aid-cncr282054040

    authors: Bajardi F

    更新日期:1984-08-15 00:00:00

  • Malignant thymoma with peripheral blood lymphocytosis.

    abstract::A 37-year-old woman with a giant, lymphocytic predominant thymoma involving the pleura and accompanied by a sharp peripheral blood lymphocytosis is described. Only electromicroscopic and immunohistologic studies could exclude the alternative diagnosis of mediastinal lymphoma. The tumor and peripheral blood lymphocytes...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19880315)61:6<1222::aid-cncr2820

    authors: Shachor Y,Radnay J,Bernheim J,Rozenszajn A,Bruderman I,Klajman A,Steiner ZP

    更新日期:1988-03-15 00:00:00

  • Management of locally advanced and disseminated breast cancer--chemotherapy.

    abstract::Breast cancer is one of the most responsive of the common solid tumors when systemic therapy is indicated in the treatment of locally advanced or disseminated cancer. Many single agents have been useful in inducing remission in mammary carcinoma, but in recent years various drug combinations have been developed that a...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19800815)46:4+<1079::aid-cncr282

    authors: Bisel HF

    更新日期:1980-08-15 00:00:00

  • Survival results in adult patients treated for medulloblastoma.

    abstract::The records of all 27 adult patients (age, greater than or equal to 16 years) diagnosed with cerebellar medulloblastoma between 1968 and 1986 were reviewed. Twenty-four patients (89%) were treated with postoperative megavoltage irradiation. Twenty of these patients underwent craniospinal irradiation. Sixteen patients ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19920415)69:8<2143::aid-cncr2820

    authors: Hazuka MB,DeBiose DA,Henderson RH,Kinzie JJ

    更新日期:1992-04-15 00:00:00

  • Kaposi's sarcoma in two lymphoma patients with hepatitis B and other infections.

    abstract::Kaposi's sarcoma developed in two lymphoma patients previously treated by chemotherapy and chemoirradiation. The histologic picture in the two cases showed a non-Hodgkin's lymphoma with multifocal epithelioid histiocytic reaction. Both patients had Hepatitis-B surface antigen and other infections due to herpes and str...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(1984)54:4<773::aid-cncr282054043

    authors: Berrebi A,Shtalrid M,Hurwitz N,Frumkin A,Schattner A

    更新日期:1984-08-15 00:00:00

  • Combination therapy with transcatheter arterial chemoembolization and percutaneous ethanol injection compared with percutaneous ethanol injection alone for patients with small hepatocellular carcinoma: a randomized control study.

    abstract:BACKGROUND:To assess whether the effectiveness of a combination of transcatheter arterial chemoembolization (TACE) and percutaneous ethanol injection (PEI) is superior to PEI alone in the treatment of patients with small hepatocellular carcinoma (HCC), a randomized controlled study was performed. METHODS:Fifty-two pat...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1002/1097-0142(20010915)92:6<1516::aid-cncr1477

    authors: Koda M,Murawaki Y,Mitsuda A,Oyama K,Okamoto K,Idobe Y,Suou T,Kawasaki H

    更新日期:2001-09-15 00:00:00

  • Serum and ascitic fluid levels of interleukin-1, interleukin-6, and tumor necrosis factor-alpha in patients with ovarian epithelial cancer.

    abstract:BACKGROUND:Recent studies have shown that multiple cytokines are secreted by ovarian epithelial cancer cells. Previous studies have shown that the cancer cell lines secrete macrophage colony-stimulating factor (M-CSF), granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin-1 (IL-1), interleukin-6 (IL-6)...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19931015)72:8<2433::aid-cncr2820

    authors: Moradi MM,Carson LF,Weinberg B,Haney AF,Twiggs LB,Ramakrishnan S

    更新日期:1993-10-15 00:00:00

  • Growth rate of 147 mammary carcinomas.

    abstract::In 147 cases of mammary carcinoma, 388 serial mammographies were performed before final treatment. The average retrospective observation time was 27 months with a range of two months to 11 years. The number of serial mammographies per case ranged between two and 11. The tumor volume doubling times (TV); obtained by me...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19800415)45:8<2198::aid-cncr2820

    authors: von Fournier D,Weber E,Hoeffken W,Bauer M,Kubli F,Barth V

    更新日期:1980-04-15 00:00:00

  • The two types of correction of absorbed dose estimates for internal emitters.

    abstract:BACKGROUND:Two types of correction for absorbed dose (D) estimates are described for clinical applications of internal emitters. The first is appropriate for legal and scientific reasons involving phantom-based estimates; the second is patient-specific and primarily intended for radioimmunotherapy (RIT). METHODS:The M...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.10290

    authors: Williams LE,Liu A,Yamauchi DM,Lopatin G,Raubitschek AA,Wong JY

    更新日期:2002-02-15 00:00:00

  • Paclitaxel, carboplatin, and long-term continuous infusion of 5-fluorouracil in the treatment of advanced squamous and other selected carcinomas: results of a Phase II trial.

    abstract:BACKGROUND:The purpose of this study was to evaluate the feasibility, toxicity, and efficacy of the combination of paclitaxel, carboplatin, and long-term continuous infusion 5-fluorouracil (5-FU) in the treatment of advanced squamous carcinomas of various primary sites. METHODS:Patients were eligible for this trial if...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章

    doi:10.1002/1097-0142(20010801)92:3<642::aid-cncr1365>

    authors: Hainsworth JD,Burris HA 3rd,Meluch AA,Baker MN,Morrissey LH,Greco FA

    更新日期:2001-08-01 00:00:00

  • Spinal cord glioma following irradiation for Hodgkin's disease.

    abstract::A 21-year-old patient, after radiation therapy to the mediastinum for Hodgkin's disease, died six years later of a spinal cord glioma, believed to be caused by irradiation therapy. That the x-ray therapy provoked neoplastic changes seems likely, although it could be coincidental. ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19800415)45:8<2051::aid-cncr2820

    authors: Clifton MD,Amromin GD,Perry MC,Abadir R,Watts C,Levy N

    更新日期:1980-04-15 00:00:00

  • Prognostic factors influencing relapse of squamous cell carcinoma of the maxillary sinus.

    abstract::In 95 surgically staged patients with squamous cell carcinoma of the maxillary sinus, multivariate regression analyses were employed to identify prognostic factors. Possible prognostic factors for local control were TNM stage and type of surgical procedures: T2 or T3 tumors and use of total maxillectomy showed better ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19850101)55:1<190::aid-cncr28205

    authors: Kondo M,Ogawa K,Inuyama Y,Yamashita S,Tominaga S,Shigematsu N,Nishiguchi I,Hashimoto S

    更新日期:1985-01-01 00:00:00

  • Association between mammographic parenchymal pattern classification and incidence of breast cancer.

    abstract::Wolfe has suggested that the mammographic parenchymal patterns can be used to identify a group with high incidence of breast cancer. To evaluate this claim, mammograms of women with breast cancer that was detected at the University of Michigan Breast Cancer Detection Demonstration Project have been classified and comp...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19800515)45:10<2550::aid-cncr282

    authors: Threatt B,Norbeck JM,Ullman NS,Kummer R,Roselle P

    更新日期:1980-05-15 00:00:00

  • Identification of novel mutations by exome sequencing in African American colorectal cancer patients.

    abstract:BACKGROUND:The purpose of this study was to identify genome-wide single nucleotide variants and mutations in African American patients with colorectal cancer (CRC). There is a need of such studies in African Americans, because they display a higher incidence of aggressive CRC tumors. METHODS:We performed whole exome s...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.28922

    authors: Ashktorab H,Daremipouran M,Devaney J,Varma S,Rahi H,Lee E,Shokrani B,Schwartz R,Nickerson ML,Brim H

    更新日期:2015-01-01 00:00:00

  • The significance of laryngeal edema following radiotherapy of carcinoma of the vocal cord.

    abstract::Laryngeal edema persisting for more than three months following radiotherapy developed in 38 of 247 (15.4%) patients irradiated for carcinoma of the vocal cord. In 17 (44.7%) of these patients, the laryngeal edema was associated with persistent or recurrent disease, although only 25.4% of the patients with uncontrolle...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19820215)49:4<655::aid-cncr28204

    authors: Fu KK,Woodhouse RJ,Quivey JM,Phillips TL,Dedo HH

    更新日期:1982-02-15 00:00:00

  • Periosteal Ewing's sarcoma.

    abstract::Ewing's sarcoma is a small cell malignant tumor that usually arises in the medullary cavity of bone. Less frequently, it originates in soft tissue and may secondarily invade underlying bone. The origin of Ewing's sarcoma in a periosteal location without extension into either the bone or adjacent soft tissue has not be...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19861015)58:8<1781::aid-cncr2820

    authors: Bator SM,Bauer TW,Marks KE,Norris DG

    更新日期:1986-10-15 00:00:00