Chinese expert consensus on the clinical diagnosis and treatment of advanced breast cancer (2018).

abstract：BACKGROUND:Nineteen patients with Ewing sarcoma of bone, each younger than 3 years of age at the time of initial presentation, are reported. These children represent an unusually young age group for documented Ewing sarcoma and represent 2.6% of all patients registered in the Intergroup Ewing's Sarcoma Study (IESS). M...

journal_title：Cancer

authors： Maygarden SJ,Askin FB,Siegal GP,Gilula LA,Schoppe J,Foulkes M,Kissane JM,Nesbit M

更新日期：1993-03-15 00:00:00

abstract：BACKGROUND:This study was performed to determine the incidence of central venous device-related blood stream infection and thrombosis in patients treated with moderate dose continuous-infusion interleukin-2 (IL-2). METHODS:The records of 160 consecutive patients treated at the University of Wisconsin Hospital and Clin...

journal_title：Cancer

authors： Eastman ME,Khorsand M,Maki DG,Williams EC,Kim K,Sondel PM,Schiller JH,Albertini MR

更新日期：2001-02-15 00:00:00

abstract：BACKGROUND:Children of different racial/ethnic backgrounds have varying risks of cancer. However, to the authors' knowledge, few studies to date have examined cancer occurrence in children of mixed ancestry. METHODS:This population-based case-control study examined cancer among children aged <15 years using linked can...

journal_title：Cancer

authors： Chow EJ,Puumala SE,Mueller BA,Carozza SE,Fox EE,Horel S,Johnson KJ,McLaughlin CC,Reynolds P,Von Behren J,Spector LG

更新日期：2010-06-15 00:00:00

abstract：:Seven patients with advanced locoregional or metastatic squamous cell carcinoma of the skin were treated with cis-daimminedichloroplatin (cisplatin) and 5-fluorouracil (5-FU). Responses were seen in six of seven patients (three partial responses [PR] and three complete responses [CR]). One patient is alive and disease...

journal_title：Cancer

authors： Khansur T,Kennedy A

更新日期：1991-04-15 00:00:00

abstract：:Twenty-two patients received specific active immunotherapy (TAA vaccine once per month for 3 months), with the duration of follow-up, as of July 1984, ranging from 3 months to 36 months (median, 21 months). Of these, seven had Dukes B2, seven had Dukes C, and eight had Dukes D lesions. All received surgical resection,...

journal_title：Cancer

authors： Hollinshead A,Elias EG,Arlen M,Buda B,Mosley M,Scherrer J

更新日期：1985-08-01 00:00:00

abstract：BACKGROUND:At the time of diagnosis of colorectal carcinoma, 2-3% of patients are likely to be harboring brain metastases, and another 10% of patients will develop brain lesions during the course of their disease. The purpose of this study was to examine the clinical course of a group of patients with metastatic brain ...

journal_title：Cancer

authors： Wroński M,Arbit E

更新日期：1999-04-15 00:00:00

abstract：BACKGROUND:[(111)In]-diethylenetriamine pentaacetic acid (DTPA)-D-[Phe1]-octreotide (OctreoScan, Mallinckrodt Medical, Petten, The Netherlands), combined with single photon emission computed tomography (SPECT), has limited possibilities to detect small abdominal endocrine tumors. This study explores the efficacy of Oct...

journal_title：Cancer

authors： Ohrvall U,Westlin JE,Nilsson S,Juhlin C,Rastad J,Lundqvist H,Akerström G

更新日期：1997-12-15 00:00:00

abstract：BACKGROUND:The echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase (EML4-ALK) fusion gene resulting from the chromosome inversion inv(2)(p21;p23) recently was identified in nonsmall cell lung cancer (NSCLC). The authors of this study investigated the frequency, genetic and clinicopathologic prof...

journal_title：Cancer

authors： Wong DW,Leung EL,So KK,Tam IY,Sihoe AD,Cheng LC,Ho KK,Au JS,Chung LP,Pik Wong M,University of Hong Kong Lung Cancer Study Group.

更新日期：2009-04-15 00:00:00

abstract：:A case of acute renal failure secondary to bilateral renal vein occlusion by a retroperitoneal plasmacytoma is described. The use of low-risk radiographic techniques including radionuclide venography and a computerized axial tomography (CAT) scan made a rapid and accurate diagnosis possible. Fatal hemorrhage occurred ...

journal_title：Cancer

authors： Marks ES,Lee KM

更新日期：1984-03-01 00:00:00

abstract：BACKGROUND:Low socioeconomic status (SES) is a reported risk factor for cervical carcinoma, but few studies have taken into account adequately the possibly confounding effects of oncogenic human papillomavirus (HPV) infection as well as access to screening and subsequent treatment. METHODS:Women (n = 5060 women) with ...

journal_title：Cancer

authors： Khan MJ,Partridge EE,Wang SS,Schiffman M

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND:Retrospective studies suggest that dose intensity is an important determinant of outcome in the treatment of patients with a variety of malignant diseases such as breast cancer, ovarian cancer, and lymphoma. Unfortunately, these results have not been clearly substantiated in prospective randomized trials. On...

journal_title：Cancer

authors： Long GD,Negrin RS,Hoyle CF,Kusnierz-Glaz CR,Schriber JR,Blume KG,Chao NJ

更新日期：1995-09-01 00:00:00

abstract：:Indirect data supporting a preexisting immunologic impairment in patients with Hodgkin's disease (HD) have been presented in recent years. These immunologic defects are supposed to be related to genetic and/or environmental factors. In this study, 65 first-degree relatives and 12 spouses of 21 consecutive patients wit...

journal_title：Cancer

authors： Merk K,Björkholm M,Tullgren O,Mellstedt H,Holm G

更新日期：1990-11-01 00:00:00

abstract：BACKGROUND:The human papillomavirus (HPV) E2 protein is a transcriptional repressor of the oncogenes E6/E7 and loss of E2 function is considered a key step in carcinogenesis. Integration of HPV into the host genome may disrupt the E2 gene. Furthermore, methylation of CpG dinucleotides in E2-binding sites (E2BSs) in the...

journal_title：Cancer

authors： Reuschenbach M,Huebbers CU,Prigge ES,Bermejo JL,Kalteis MS,Preuss SF,Seuthe IM,Kolligs J,Speel EJ,Olthof N,Kremer B,Wagner S,Klussmann JP,Vinokurova S,von Knebel Doeberitz M

更新日期：2015-06-15 00:00:00

abstract：:The abdominoinguinal incision is a new method for exposure and resection of tumors in the pelvis with lateral fixation that were previously called unresectable or were treated with hemipelvectomy. This procedure has been used in 22 patients referred from other centers following unsuccessful resection attempts. Twelve ...

journal_title：Cancer

authors： Karakousis CP

更新日期：1984-12-01 00:00:00

abstract：:Oat-cell carcinoma of the thymus gland is exceedingly rare as a primary lesion, and only a few cases have been reported. We report a case in which a neoplasm interpreted as an oat-cell carcinoma was intimately associated with and arose in transition from a carcinoid tumor of the thymus. Ultrastructural features of thi...

journal_title：Cancer

authors： Wick MR,Scheithauer BW

更新日期：1982-04-15 00:00:00

abstract：BACKGROUND:Adequate prediction of survival is important in deciding on treatment for patients with symptomatic spinal metastases. The authors reviewed 342 patients with painful spinal metastases without neurologic impairment who were treated conservatively within a large, prospectively randomized radiotherapy trial. Re...

journal_title：Cancer

authors： van der Linden YM,Dijkstra SP,Vonk EJ,Marijnen CA,Leer JW,Dutch Bone Metastasis Study Group.

更新日期：2005-01-15 00:00:00

abstract：BACKGROUND:The term poorly differentiated (PD) carcinoma was proposed 20 years ago to define aggressive, follicular-derived thyroid carcinomas with behavior intermediate between follicular/papillary and anaplastic carcinomas. Among the variable histologic patterns recognized in such tumors, trabecular-insular-solid (TI...

journal_title：Cancer

authors： Volante M,Landolfi S,Chiusa L,Palestini N,Motta M,Codegone A,Torchio B,Papotti MG

更新日期：2004-03-01 00:00:00

abstract：:In a pathologic review of 1224 cases of endometrial carcinoma, 1023 were confirmed cases of endometrial carcinoma. Fifty-six (5.5%) were clear-cell adenocarcinoma (CCE). Fifteen cases of "secretory carcinoma" (SCE) were examined for comparison. Fifty-five patients with CCE and all with SCE were followed for at least f...

journal_title：Cancer

authors： Christopherson WM,Alberhasky RC,Connelly PJ

更新日期：1982-04-15 00:00:00

abstract：:The exact nature of the association between hormones and the development of breast cancer remains uncertain. Studies of endogenous hormone levels and breast cancer suggest a possible role of estrogens and androgens in the cause of breast cancer. Numerous studies have been conducted to assess the risk of breast cancer ...

journal_title：Cancer

authors： Helzlsouer KJ,Couzi R

更新日期：1995-11-15 00:00:00

abstract：BACKGROUND:Patients with familial adenomatous polyposis develop periampullary adenomas at a high rate. However, little is known regarding the factors that control the growth, the natural history, or the malignant potential of these tumors. METHODS:In this study, the authors systematically evaluated the expression of t...

journal_title：Cancer

authors： Resnick MB,Gallinger S,Wang HH,Odze RD

更新日期：1995-07-15 00:00:00

abstract：:Distant nontraumatic clostridial myonecrosis in association with malignancy is an uncommon disorder, with only 14 well-documented cases previously reported in the English literature. Clostridium perfringens and C. septicum are the most common organisms, usually gaining access to the circulation through an ulcerated le...

journal_title：Cancer

authors： Kaiser CW,Milgrom ML,Lynch JA

更新日期：1986-02-15 00:00:00

abstract：BACKGROUND:The phosphatidylinositol-3 kinase (PI3K)/Akt/mammalian target of rapamycin (mTOR) pathway is dysregulated in patients with metastatic renal cell carcinoma (mRCC). Buparlisib is a pan-PI3K inhibitor with activity in advanced solid tumors. The primary objective of the current study was to determine the maximum...

journal_title：Cancer

authors： McKay RR,De Velasco G,Werner L,Bellmunt J,Harshman L,Sweeney C,Rosenberg JE,Hirsch M,Signoretti S,Van Allen EM,Walsh M,Vaishampayan U,McDermott DF,Choueiri TK

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:It has been previously observed that patients with head and neck squamous cell carcinoma or with laryngeal leucoplakia present a significant reduction in plasma folate levels. The current Phase IIA pilot study assessed the effectiveness of folic acid as a chemopreventive agent in patients affected by glottic...

journal_title：Cancer

authors： Almadori G,Bussu F,Navarra P,Galli J,Paludetti G,Giardina B,Maurizi M

更新日期：2006-07-15 00:00:00

abstract：:Five hundred and sixty-six patients with either Stage III or IV Hodgkin's disease were prospectively randomized to test whether CCNU and/or vinblastine are more effective than mechlorethamine and/or vincristine with procarbazine and prednisone. The combination of CCNU, vinblastine, procarbazine, and prednisone (CVPP) ...

journal_title：Cancer

authors： Cooper MR,Pajak TF,Nissen NI,Stutzman L,Brunner K,Cuttner J,Falkson G,Grunwald H,Bank A,Leone L,Seligman BR,Silver RT,Weiss RB,Haurani F,Blom J,Spurr CL,Glidewell OJ,Gottlieb AJ,Holland JF

更新日期：1980-08-15 00:00:00

abstract：:The observation, in 1980, of a rapid increase in platelet counts as a result of administration of intravenous immunoglobulin (IVIG) in a patient with immune thrombocytopenic purpura (ITP) was followed by clinical studies confirming the efficacy of this new treatment alternative in ITP. Simultaneously, new sensitive as...

journal_title：Cancer

authors： Imbach P

更新日期：1991-09-15 00:00:00

abstract：:Meaning and purpose in life are associated with the mental and physical health of patients with cancer and survivors and also constitute highly valued outcomes in themselves. Because meaning and purpose are often threatened by a cancer diagnosis and treatment, interventions have been developed to promote meaning and p...

journal_title：Cancer

authors： Park CL,Pustejovsky JE,Trevino K,Sherman AC,Esposito C,Berendsen M,Salsman JM

更新日期：2019-07-15 00:00:00

abstract：:Seventy-eight patients with disseminated testicular cancer were entered on a random prospective study evaluating three separate remission induction arms. Therapy with cis-diamminedichloroplatinum (20 mg/M2 for five consecutive days every three weeks for 3-4 courses) and bleomycin (30 units intravenous push weekly for ...

journal_title：Cancer

authors： Einhorn LH,Williams SD

更新日期：1980-09-15 00:00:00

abstract：BACKGROUND:The objective of this study was to determine whether a very low presenting prostate-specific antigen (PSA) level was associated with greater prostate cancer-specific mortality (PCSM) among men with a Gleason score (GS) of 8 to 10. METHODS:The Surveillance, Epidemiology, and End Results program was used to i...

journal_title：Cancer

authors： Mahal BA,Aizer AA,Efstathiou JA,Nguyen PL

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:CXC chemokine receptor 4 (CXCR4) is activated by phosphorylation (pCXCR4) and is essential for the migration of hematopoietic precursors to bone marrow. CXCR4 overexpression predicts a poor prognosis in patients with acute myeloid leukemia. Data regarding the prognostic impact of CXCR4 in patients with B-acu...

journal_title：Cancer

authors： Konoplev S,Jorgensen JL,Thomas DA,Lin E,Burger J,Kantarjian HM,Andreeff M,Medeiros LJ,Konopleva M

更新日期：2011-10-15 00:00:00

abstract：:Chlorozotocin was administered by rapid intravenous infusion to 35 patients with advanced cancer on either single-day of five-consecutive-day schedules. Total doses per course ranged from 12.5 to 200 mg/m2. On either administration schedule, dose limiting toxicities were thrombocytopenia and leukopenia at total doses ...

journal_title：Cancer

authors： Kovach JS,Moertel CG,Schutt AJ,Frytak S,O'Connell MJ,Rubin J,Ingle JN

更新日期：1979-06-01 00:00:00