Abstract:
:Non-Hodgkin's lymphoma confined to the liver is unusual in adults and has not been reported in children. Two children with primary hepatic and one with hepatosplenic NHL are described. All three patients are males, and both tumors examined for cell surface markers were of B-cell origin. Two patients, treated with chemotherapy and radiation, developed disseminated disease and died with 7 months of diagnosis. A third patient treated aggressively with radiotherapy and multiagent chemotherapy (LSA2-L2 protocol) remains in complete continuous remission 22 months after initiation of therapy. Hepatic NHL, even if well localized at diagnosis appears to warrant an aggressive therapeutic approach.
journal_name
Cancerjournal_title
Cancerauthors
Miller ST,Wollner N,Meyers PA,Exelby P,Jereb B,Miller DRdoi
10.1002/1097-0142(19831215)52:12<2285::aid-cncr282subject
Has Abstractpub_date
1983-12-15 00:00:00pages
2285-8issue
12eissn
0008-543Xissn
1097-0142journal_volume
52pub_type
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