Primary hepatic or hepatosplenic non-Hodgkin's lymphoma in children.

Abstract:

:Non-Hodgkin's lymphoma confined to the liver is unusual in adults and has not been reported in children. Two children with primary hepatic and one with hepatosplenic NHL are described. All three patients are males, and both tumors examined for cell surface markers were of B-cell origin. Two patients, treated with chemotherapy and radiation, developed disseminated disease and died with 7 months of diagnosis. A third patient treated aggressively with radiotherapy and multiagent chemotherapy (LSA2-L2 protocol) remains in complete continuous remission 22 months after initiation of therapy. Hepatic NHL, even if well localized at diagnosis appears to warrant an aggressive therapeutic approach.

journal_name

Cancer

journal_title

Cancer

authors

Miller ST,Wollner N,Meyers PA,Exelby P,Jereb B,Miller DR

doi

10.1002/1097-0142(19831215)52:12<2285::aid-cncr282

subject

Has Abstract

pub_date

1983-12-15 00:00:00

pages

2285-8

issue

12

eissn

0008-543X

issn

1097-0142

journal_volume

52

pub_type

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