A uniform residual tumor (R) classification: integration of the R classification and the circumferential margin status.

abstract：BACKGROUND:Although it is believed that p53 suppressor gene mutations, compared with mutations in the K-ras oncogene, occur at a later stage of colorectal tumorigenesis, the distribution of these genetic alterations at an early stage remains poorly characterized. METHODS:The authors analyzed the immunoreactivity for p...

journal_title：Cancer

authors： Hosaka S,Aoki Y,Akamatsu T,Nakamura N,Hosaka N,Kiyosawa K

更新日期：2002-01-01 00:00:00

abstract：:Two children with cancer that persisted after multiple exploratory laparotomies, external beam radiation therapy, and multidrug chemotherapy had gold 198 (198Au) seeds implanted into their localized but unresectable tumor. Both children are alive, are receiving no therapy, and are disease-free more than 2 years later....

journal_title：Cancer

authors： Knight PJ,Doornbos JF,Rosen D,Lin JJ,Farha GJ

更新日期：1986-03-01 00:00:00

abstract：:Necropsy and clinical data show that primary hepatocellular carcinoma (PHC) is the commonest cancer among the Senoi (a Malaysian aboringine group). The other aboringine tribes do not appear to have this high predilection for liver cancer. In the necropsy series, PHS was present in 10 out of 22 Senoi patients with cirr...

journal_title：Cancer

authors： Sumithran E,Prathap K

更新日期：1977-10-01 00:00:00

abstract：:Although clinically evident thyroid carcinoma is not a frequent neoplasm (incidence 2.7 per 100,000 persons in La Plata, Argentina), occult carcinomas are present in a high proportion of the population, but there are marked differences along geographical lines. The purpose of the present study is to establish the prev...

journal_title：Cancer

authors： Ottino A,Pianzola HM,Castelletto RH

更新日期：1989-07-15 00:00:00

abstract：BACKGROUND:Previous studies have shown that matrix metalloproteinase-2 (MMP-2) (a 72-kilodalton Type IV collagenase/gelatinase A) is associated with breast carcinoma, but to the authors' knowledge there are no reports showing that it is prognostic for overall survival. METHODS:Expression of the immunoreactive protein ...

journal_title：Cancer

authors： Talvensaari-Mattila A,Pääkkö P,Höyhtyä M,Blanco-Sequeiros G,Turpeenniemi-Hujanen T

更新日期：1998-09-15 00:00:00

abstract：BACKGROUND:Modified nucleosides such as 1-methyl-adenosine and pseudouridine exist as minute components of transfer ribonucleic acid (tRNA) and are excreted in the urine in large amounts in the presence of malignancy. Although use of these modified nucleosides as tumor markers has long been studied and many reports hav...

journal_title：Cancer

authors： Masuda M,Nishihira T,Itoh K,Mizugaki M,Ishida N,Mori S

更新日期：1993-12-15 00:00:00

abstract：:Forty-five immunocompetent patients with solid tumors were immunized with BCG, PPD, and tumor cells. The methods were practical, but the morbidity was significant, including painful draining ulcerations at vaccine sites, possible enhancement of tumor growth in three patients, and the discovery at autopsy of systemic t...

journal_title：Cancer

authors： Gerner RE,Moore GE

更新日期：1976-07-01 00:00:00

abstract：:During the past 30 years, changes in the treatment of children and adolescents with cancer have led to substantial improvements in survival. Although treatment-related factors have been shown to impact subsequent health status and quality of life, there is limited information on survivors who are now two or more decad...

journal_title：Cancer

authors： Robison LL,Green DM,Hudson M,Meadows AT,Mertens AC,Packer RJ,Sklar CA,Strong LC,Yasui Y,Zeltzer LK

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:Recurrent central neurocytoma is very rare and to the authors' knowledge data regarding its response to chemotherapy currently are not available. METHODS:Three patients with progressive neurocytoma received chemotherapy after their informed consent was obtained. Disease recurred in two patients after surger...

journal_title：Cancer

authors： Brandes AA,Amistà P,Gardiman M,Volpin L,Danieli D,Guglielmi B,Carollo C,Pinna G,Turazzi S,Monfardini S

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:If some adenomas do not bleed over several years, they will cause systematic false-negative fecal immunochemical test (FIT) results. The long-term effectiveness of FIT screening has been estimated without accounting for such systematic false-negativity. There are now data with which to evaluate this issue. ...

journal_title：Cancer

authors： van der Meulen MP,Lansdorp-Vogelaar I,van Heijningen EM,Kuipers EJ,van Ballegooijen M

更新日期：2016-06-01 00:00:00

abstract：:In a randomized series of 70 patients with with colo rectal adenocarcinoma, a comparison of systemic 5-fluorouracil chemotherapy administered as a continuous 120-hours infusion vs. intravenous bolus injection daily for 5 days demonstrated superiority of prolonged intravenous infusion. The most striking advantage of pr...

journal_title：Cancer

authors： Seifert P,Baker LH,Reed ML,Vaitkevicius VK

更新日期：1975-07-01 00:00:00

abstract：:Peripheral blood changes preceding therapy-related leukemia were studied in 105 patients who had received cytotoxic therapy, 53 for Hodgkin's disease and 52 for other cancers. Preleukemic anomalies were observed in 74.3% of the cases, appearing after a mean interval of 68.7 months after diagnosis of the initial cancer...

journal_title：Cancer

authors： De Gramont A,Louvet C,Krulik M,Smadja N,Donadio D,Laporte JP,Brissaud P,Smith M,Delâge JM,Drolet Y

更新日期：1986-08-01 00:00:00

abstract：BACKGROUND:Heparanase up-regulation has been correlated with reduced postoperative survival in various cancers. METHODS:Heparanase expression was analyzed in 60 consenting tongue (mobile) cancer patients by means of immunohistochemistry. Heparanase levels were also analyzed in the saliva of both healthy controls and t...

journal_title：Cancer

authors： Nagler R,Ben-Izhak O,Cohen-Kaplan V,Shafat I,Vlodavsky I,Akrish S,Ilan N

更新日期：2007-12-15 00:00:00

abstract：:Chemokines are chemoattractant cytokines that regulate the trafficking and activation of leukocytes and other cell types under a variety of inflammatory and noninflammatory conditions. Over the past few years, studies have increasingly shown that chemokines play an important role in several aspects of tumor progressio...

journal_title：Cancer

authors： Ruffini PA,Morandi P,Cabioglu N,Altundag K,Cristofanilli M

更新日期：2007-06-15 00:00:00

abstract：BACKGROUND:Investigations regarding the impact of tumor biology after surgical management of colorectal liver metastasis have focused largely on overall survival. We investigated the impact of codon-specific KRAS mutations on the rates and patterns of recurrence in patients after surgery for colorectal liver metastasis...

journal_title：Cancer

authors： Margonis GA,Kim Y,Sasaki K,Samaha M,Amini N,Pawlik TM

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:A previous study found that medroxyprogesterone acetate (MPA) delayed the in vivo growth of three (AsPC-1, Capan-2, and MiaPaCa-2) of nine human pancreatic carcinoma cell lines transplanted into nude mice (Cancer 1995; 75:1263-72). The current study was undertaken to evaluate the basis for this inhibitor. M...

journal_title：Cancer

authors： Abe M,Yamashita J,Ogawa M

更新日期：2000-05-01 00:00:00

abstract：:Laparoscopy is highly effective in diagnosing malignant liver disease, with overall accuracy in the 90% range. Up to 80% of the liver surface can be inspected, and biopsies can be directed with precision. A major advantage over scan guided percutaneous techniques is the ability to detect and biopsy lesions only a few ...

journal_title：Cancer

authors： Lightdale CJ

更新日期：1982-12-01 00:00:00

abstract：:The cytologic results of 34 fine-needle aspiration (FNA) biopsies of the central nervous system (CNS) are reported. There were 31 intraoperative biopsies performed at the time of craniotomy. All the cases were diagnosed using direct smear preparations stained with Papanicolaou and Diff-Quik (Harleco, NJ) stains. The s...

journal_title：Cancer

authors： Silverman JF,Timmons RL,Leonard JR 3rd,Hardy IM,Harris LS,O'Brien K,Norris HT

更新日期：1986-09-01 00:00:00

abstract：:Combined modality therapy consisting of CHOP-Bleo (cyclophosphamide, Adriamycin [doxorubicin], vincristine (Oncovin), prednisone, and bleomycin) and limited-field radiotherapy was given to 47 patients with Stage III and IIIE diffuse large cell lymphomas. Overall 5-year survival and disease-free survival figures are 64...

journal_title：Cancer

authors： Velasquez W,Fuller LM,Oh KK,Hagemeister FB,Sullivan JA,Manning JT,Shullenberger CC

更新日期：1984-04-01 00:00:00

abstract：:In 14 patients by bilateral retroperitoneal lymph node dissection for nonseminoma tumors of the testes, several sexual functions before and after node dissection were compared. All patients had normal sexual function before the operation. After the operation, antegrade ejaculation was found to have disappeared complet...

journal_title：Cancer

authors： Nijman JM,Jager S,Boer PW,Kremer J,Oldhoff J,Koops HS

更新日期：1982-12-15 00:00:00

abstract：BACKGROUND:Programmed death 1 (PD-1) signaling in the tumor microenvironment dampens immune responses to cancer, and blocking this axis induces antitumor effects in several malignancies. Clinical studies of PD-1 blockade are only now being initiated in pediatric patients, and little is known regarding programmed death-...

journal_title：Cancer

authors： Majzner RG,Simon JS,Grosso JF,Martinez D,Pawel BR,Santi M,Merchant MS,Geoerger B,Hezam I,Marty V,Vielh P,Daugaard M,Sorensen PH,Mackall CL,Maris JM

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:There is good prognostic correlation for the two microstaging systems, Breslow depth and Clark level, commonly used to stage melanomas. Many investigators have reported that Breslow depth is the superior microstaging method. Although Clark level has been dropped from most of the proposed American Joint Commi...

journal_title：Cancer

authors： Owen SA,Sanders LL,Edwards LJ,Seigler HF,Tyler DS,Grichnik JM

更新日期：2001-03-01 00:00:00

abstract：:Giant sections from cystectomy specimens in 45 cases of bladder cancer were examined microscopically after en bloc fixation and processing. There were 35 transitional cell, seven squamous cell, and three mixed transitional cell and squamous carcinomas. Broad front invasion was associated with papillary and superficial...

journal_title：Cancer

authors： Soto EA,Friedell GH,Tiltman AJ

更新日期：1977-02-01 00:00:00

abstract：:The current results of trials testing combined surgery and chemotherapy in patients with breast cancer is reviewed. Information concerning eight trials utilizing nine single-agent regimens was obtained. The results at this time are conflicting. There appear to be differences among the regimens utilized in the various ...

journal_title：Cancer

authors： Tormey DC

更新日期：1975-09-01 00:00:00

abstract：:The exact nature of the association between hormones and the development of breast cancer remains uncertain. Studies of endogenous hormone levels and breast cancer suggest a possible role of estrogens and androgens in the cause of breast cancer. Numerous studies have been conducted to assess the risk of breast cancer ...

journal_title：Cancer

authors： Helzlsouer KJ,Couzi R

更新日期：1995-11-15 00:00:00

abstract：BACKGROUND:The goal of this study was to examine the clinical significance of ZNF217 amplification and assess whether ZNF217 could be a potential therapeutic target in ovarian clear cell carcinoma (OCCC). METHODS:ZNF217 expression and amplification in OCCC was assessed by immunohistochemistry, fluorescence in situ hyb...

journal_title：Cancer

authors： Rahman MT,Nakayama K,Rahman M,Nakayama N,Ishikawa M,Katagiri A,Iida K,Nakayama S,Otsuki Y,Shih IeM,Miyazaki K

更新日期：2012-06-01 00:00:00

abstract：:If radical surgery is the only rational policy for most cases of rectal cancer, the problem of local treatment in poor surgical risk patients should be discussed in selected cases. Only limited, fairly-well-differentiated tumors, still confined to the rectal wall may have a sufficiently low probability of lymphatic sp...

journal_title：Cancer

authors： Papillon J

更新日期：1975-08-01 00:00:00

abstract：:Peripheral blood lymphocytes of patients with multiple myeloma, macroglobulinemia, and monoclonal gammopathy of uncertain significance were analyzed for B cells, and cells bearing kappa light chains and lambda light chains on their surfaces. Compared with controls, the number of B cells were decreased in all three gro...

journal_title：Cancer

authors： Dillman RO,Royston I,Meserve BL,Griffiths JC

更新日期：1981-11-15 00:00:00

abstract：BACKGROUND:Screening colonoscopy (SC) for colorectal cancer (CRC) is underused by Latino individuals. The current randomized clinical trial examined the impact of 3 interventions: 1) patient navigation; 2) patient navigation plus standard Centers for Disease Control and Prevention print materials; and 3) patient naviga...

journal_title：Cancer

authors： DuHamel KN,Schofield EA,Villagra C,Sriphanlop P,Itzkowitz SH,Cotter G,Cohen N,Erwin DO,Winkel G,Thompson HS,Zauber AG,Jandorf LH

更新日期：2020-02-15 00:00:00

abstract：BACKGROUND:In the United States, incidence rates for malignant tumors of the uterine corpus are lower among blacks than among whites, whereas mortality rates are higher among blacks. Reasons for the higher level of mortality among blacks have been debated. METHODS:Using data from the Surveillance, Epidemiology, and En...

journal_title：Cancer

authors： Sherman ME,Devesa SS

更新日期：2003-07-01 00:00:00