A phase 2 trial of erlotinib in patients with previously treated squamous cell and adenocarcinoma of the esophagus.

abstract：:A case of acute renal failure secondary to bilateral renal vein occlusion by a retroperitoneal plasmacytoma is described. The use of low-risk radiographic techniques including radionuclide venography and a computerized axial tomography (CAT) scan made a rapid and accurate diagnosis possible. Fatal hemorrhage occurred ...

journal_title：Cancer

authors： Marks ES,Lee KM

更新日期：1984-03-01 00:00:00

abstract：:The case of a 71-year-old woman who developed generalized weakness, lymphadenopathy, and a skin rash during methyldopa therapy is described. The prompt disappearance of symptoms following the discontinuation of the drug implicates it in the initial triggering of the abnormal lymphoid proliferation. Shortly thereafter,...

journal_title：Cancer

authors： Weisenburger DD

更新日期：1978-11-01 00:00:00

abstract：BACKGROUND:The intraoperative evaluation of axillary sentinel lymph nodes (SLNs) allows the surgeon to complete axillary dissection in 1 setting at the time of the primary breast surgery. However, to the authors' knowledge, there is no consensus regarding the optimal method for intraoperative evaluation of SLNs in brea...

journal_title：Cancer

authors： Krishnamurthy S,Meric-Bernstam F,Lucci A,Hwang RF,Kuerer HM,Babiera G,Ames FC,Feig BW,Ross MI,Singletary E,Hunt KK,Bedrosian I

更新日期：2009-04-01 00:00:00

abstract：:In an Easter Cooperative Oncology Group trial, Cytoxan-prednisone (CP) Induction was compared to BCNU-prednisone (BP) in 273 patients with lymphocytic lymphoma. Response rates were comparable, with 21% achieving complete response and 40%, partial response. Patients with a nodular pattern responded better. Maintenance ...

journal_title：Cancer

authors： Ezdinli E,Pocock S,Berard CW,Aungst CW,Silverstein M,Horton J,Bennett J,Bakemeier R,Stolbach L,Perlia C,Brunk SF,Lenhard RE,Klaassen DJ,Richter P,Carbone P

更新日期：1976-09-01 00:00:00

abstract：BACKGROUND:This study was designed to evaluate the significance of tumor angiogenesis and angiogenic factors such as hepatocyte growth factor (HGF) and c-Met in determining the prognoses of 93 patients with endometrial carcinoma. METHODS:By immunohistochemical staining, this retrospective study investigated tumor angi...

journal_title：Cancer

authors： Wagatsuma S,Konno R,Sato S,Yajima A

更新日期：1998-02-01 00:00:00

abstract：:This study explores the patterns of recurrence after "curative" operation for colorectal cancer. For an 11-year period, 1960-1971, 281 evaluable patients were resected at the Peter Bent Brigham Hospital. Crude five-year survival in these patients was 49%, but only 10% of those with recurrence lived five years. A total...

journal_title：Cancer

authors： Olson RM,Perencevich NP,Malcolm AW,Chaffey JT,Wilson RE

更新日期：1980-06-15 00:00:00

abstract：BACKGROUND:The growing diversity of the population of the United States and the high burden of cancer-related symptoms reflect the need for caregiver research within underserved groups. In this longitudinal study, the authors assessed changes in symptom severity in caregivers and underserved minority patients diagnosed...

journal_title：Cancer

authors： Palos GR,Mendoza TR,Liao KP,Anderson KO,Garcia-Gonzalez A,Hahn K,Nazario A,Ramondetta LM,Valero V,Lynch GR,Jibaja-Weiss ML,Cleeland CS

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:Soft tissue sarcomas of the head and neck represent uncommon malignant neoplasms. With the exception of orbital and parameningeal sites, the treatment of sarcomas in the head and neck has not been standardized. The authors used a prospectively collected database of adult soft tissue sarcomas to identify prog...

journal_title：Cancer

authors： Kraus DH,Dubner S,Harrison LB,Strong EW,Hajdu SI,Kher U,Begg C,Brennan MF

更新日期：1994-07-15 00:00:00

abstract：:One hundred twenty-three women younger than 70 years of age and at clinical Stages I or II were enrolled in a randomized clinical trial of radical versus extended radical mastectomy. The 5-year survival rates in the radical and extended radical groups were 75 +/- 6.7% and 80 +/- 6.7%, respectively. (Cox P value for co...

journal_title：Cancer

authors： Meier P,Ferguson DJ,Karrison T

更新日期：1985-02-15 00:00:00

abstract：:Twenty patients with malignant hepatoma were treated with sequential intraarterial doxorubicin (72-hour continuous infusion) followed by systemic 5-fluorouracil (5-FU) and semustine (methyl CCNU). Objective tumor responses were seen in three patients (15%). The durations of response were 6, 19, and 27+ months, respect...

journal_title：Cancer

authors： O'Connell MJ,Hahn RG,Rubin J,Moertel CG

更新日期：1988-09-15 00:00:00

abstract：:Parathyroid adenomas are subdivided into chief cell and oxyphil cell variants. However, the parathyroid carcinomas described thus far have been only of the chief cell type. Two cases of oxyphil cell carcinoma of the parathyroid gland are reported, with light and electron microscopic study. The patients presented appar...

journal_title：Cancer

authors： Obara T,Fujimoto Y,Yamaguchi K,Takanashi R,Kino I,Sasaki Y

更新日期：1985-04-01 00:00:00

abstract：:Oral rhabdomyosarcoma (RMS) was studied by analysis of eight such cases which presented over a 25-year period. Rhabdomyosarcoma was the fourth most common oral sarcoma (7.5%) from this period after osteosarcoma (32%), fibrosarcoma (19%), and chondrosarcoma (9%). In patients younger than 20 years, RMS was the second mo...

journal_title：Cancer

authors： Peters E,Cohen M,Altini M,Murray J

更新日期：1989-03-01 00:00:00

abstract：:Comparison of 50 proliferating trichilemmal cysts with 50 "ordinary" trichilemmal cysts indicated that both types almost invariably occurred on the scalps of women, were diagnosed clinically as cysts, followed a benign course, and featured trichilemmal keratinization. A spectrum was observed from trichilemmal cyst wit...

journal_title：Cancer

authors： Brownstein MH,Arluk DJ

更新日期：1981-09-01 00:00:00

abstract：BACKGROUND:Between January 11, 1991 and January 8, 1992, 104 patients with previously untreated, invasive, primitive breast carcinoma were admitted to the authors' hospital. METHODS:For each patient, flow cytometry DNA analyses on frozen samples and on immunohistochemical staining were performed, including Ki-67, cycl...

journal_title：Cancer

authors： Michels JJ,Duigou F,Marnay J,Henry-Amar M,Delozier T,Denoux Y,Chasle J

更新日期：2003-03-15 00:00:00

abstract：BACKGROUND:Sedentary behaviors are associated with poor health outcomes in the general population, but their clinical impact on adult survivors of childhood acute lymphoblastic leukemia (ALL) has not been characterized to date. In the current study, we described the prevalence of sedentary behaviors in survivors of ALL...

journal_title：Cancer

authors： Howell CR,Wilson CL,Ehrhardt MJ,Partin RE,Kaste SC,Lanctot JQ,Pui CH,Robison LL,Hudson MM,Ness KK

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Partial nephrectomy (PN) is recommended for localized T1a (≤4 cm) renal masses and is preferred over radical nephrectomy (RN) for amenable T1b/T2 (>4 cm) tumors. The objective of the current study was to assess overall survival (OS) differences between PN and RN in patients with T1 and T2 renal cell carcinom...

journal_title：Cancer

authors： Ristau BT,Handorf EA,Cahn DB,Kutikov A,Uzzo RG,Smaldone MC

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:Response rates in chronic myeloid leukemia (CML) are now reported based on the cumulative incidence of a single-time best response. The study aim was to examine the significance of different response criteria for CML on imatinib therapy. METHODS:In all, 276 patients with chronic phase CML on imatinib therap...

journal_title：Cancer

authors： Kantarjian H,O'Brien S,Shan J,Huang X,Garcia-Manero G,Faderl S,Ravandi-Kashani F,Verstovsek S,Beth Rios M,Cortes J

更新日期：2008-02-15 00:00:00

abstract：BACKGROUND:Systemic anticancer therapies can produce acute and chronic organ damage, but the eye is usually considered a protected site. Nonetheless, the oculo-visual system has a potentially high degree of sensitivity to toxic substances. Ocular toxicity induced by cancer chemotherapy includes a broad spectrum of diso...

journal_title：Cancer

authors： al-Tweigeri T,Nabholtz JM,Mackey JR

更新日期：1996-10-01 00:00:00

abstract：:K-ras gene mutation in colorectal tumors from patients with familial polyposis coli were investigated using oligonucleotide probes specific for a mutation at codon 12, 13, or 61 of the K-ras gene. The authors examined 22 colorectal carcinomas and 51 colorectal adenomas from 41 familial polyposis coli patients and obse...

journal_title：Cancer

authors： Sasaki M,Sugio K,Sasazuki T

更新日期：1990-06-01 00:00:00

abstract：BACKGROUND:Cyclins, cyclin dependent kinases (cdks), and their inhibitors act in combination to regulate progression through the cell cycle and often are dysregulated in carcinoma. The authors hypothesized that cyclin E plays an important role in ovarian carcinogenesis and that its overexpression may be an indicator of...

journal_title：Cancer

authors： Rosen DG,Yang G,Deavers MT,Malpica A,Kavanagh JJ,Mills GB,Liu J

更新日期：2006-05-01 00:00:00

abstract：:The clinical diagnosis of lymphangitic carcinomatosis of the lung has generally been confirmed by open lung or transthoracic needle biopsy, precedures with significant morbidity and mortality, particularly in patients with respiratory insufficiency. We present six cases of lymphangitic carcinomatosis diagnosed by tran...

journal_title：Cancer

authors： Aranda C,Sidhu G,Sasso LA,Adams FV

更新日期：1978-10-01 00:00:00

abstract：:Biopsy specimens from 62 human single primary squamous cell carcinomas (SCC) of the head and neck were xenografted into nude mice. To evaluate the prognostic significance of successful heterotransplantation, the 62 cases were retrospectively examined for survival, adjusting for possible confounders by multivariate ana...

journal_title：Cancer

authors： Zätterström UK,Wennerberg J,Attewell R,Ask A

更新日期：1990-07-01 00:00:00

abstract：:Extracardiac rhabdomyomas are rare benign neoplasms that in the past have been divided by histologic criteria into adult and fetal types. In this series, 15 previously unpublished cases are presented and analyzed in combination with 51 acceptable cases from the literature. The adult type of rhabdomyoma occurs almost e...

journal_title：Cancer

authors： Di Sant'Agnese PA,Knowles DM 2nd

更新日期：1980-08-15 00:00:00

abstract：BACKGROUND:Bortezomib is active in heavily pretreated multiple myeloma patients; the dose-limiting toxicity is peripheral neuropathy (PN). METHODS:The authors retrospectively reviewed the incidence, severity, and risk factors for PN in 78 patients who received bortezomib. The median age was 57 years (range, 33-80 year...

journal_title：Cancer

authors： Badros A,Goloubeva O,Dalal JS,Can I,Thompson J,Rapoport AP,Heyman M,Akpek G,Fenton RG

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND:Metastasectomy is standard of care for pediatric patients with metastatic sarcoma with limited disease. For patients with unresectable disease, stereotactic body radiotherapy (SBRT) may serve as an alternative. Herein, the authors report the results of a prospective, multi-institutional phase 2 trial of SBRT...

journal_title：Cancer

authors： Elledge CR,Krasin MJ,Ladra MM,Alcorn SR,Han P,Gibbs IC,Hiniker SM,Laack NN,Terezakis SA

更新日期：2020-11-10 00:00:00

abstract：BACKGROUND:Conditional survival is clinically useful, particularly for patients with malignant disease who have a poor prognosis. However, there are no published data on the conditional median survival of patients with advanced carcinoma on a population basis. METHODS:Data on 217,573 patients with breast, colorectal, ...

journal_title：Cancer

authors： Kato I,Severson RK,Schwartz AG

更新日期：2001-10-15 00:00:00

abstract：:Extrarenal Wilms' tumor is a very rare disease, occurring mostly in children. Sixteen cases have been reported in the world medical literature. A case of retroperitoneal extrarenal Wilms' tumor is reported in a 36-year old white male and the literature reviewed. Pathologic examination revealed both undifferentiated re...

journal_title：Cancer

authors： Koretz MJ,Wang S,Klein FA,Lawrence W Jr

更新日期：1987-11-15 00:00:00

abstract：:Kaposi's sarcoma of the gingiva and skin developed in an HIV-negative renal transplant patient while he was receiving cyclosporine therapy. The Kaposi's sarcoma developed shortly after the patient had an acute infection with cytomegalovirus (CMV). Electron microscopy of the tumor's established cell line showed two typ...

journal_title：Cancer

authors： Siegal B,Levinton-Kriss S,Schiffer A,Sayar J,Engelberg I,Vonsover A,Ramon Y,Rubinstein E

更新日期：1990-02-01 00:00:00

abstract：BACKGROUND:This study was conducted to evaluate the long-term outcomes in patients with stage IE and IIE mucosa-associated lymphoid tissue (MALT) lymphomas treated with involved field radiotherapy (RT). METHODS:Between 1989 and 2004, 192 patients with stage I and II MALT lymphomas were treated. The report focuses on 1...

journal_title：Cancer

authors： Goda JS,Gospodarowicz M,Pintilie M,Wells W,Hodgson DC,Sun A,Crump M,Tsang RW

更新日期：2010-08-15 00:00:00

abstract：BACKGROUND:The objective of this study was to describe characteristics at diagnosis and outcomes of adults with soft tissue sarcoma. METHODS:The authors conducted a retrospective multicenter study of 12,262 patients who were treated between January 1980 and 31 December 2013 in French Sarcoma Group centers and enrolled...

journal_title：Cancer

authors： Penel N,Coindre JM,Giraud A,Terrier P,Ranchere-Vince D,Collin F,Guellec SLE,Bazille C,Lae M,de Pinieux G,Ray-Coquard IL,Bonvalot S,Cesne ALE,Robin YM,Stoeckle E,Toulmonde M,Blay JY

更新日期：2018-03-15 00:00:00