A case-control study of stomach cancer in a coal mining region of Pennsylvania.

abstract：BACKGROUND:Prostate specific antigen (PSA) is useful as a tumor marker for monitoring patients with prostate cancer after definitive therapy. Limitations have been noted when PSA was used for the early detection of prostate cancer. The use of prostate specific antigen density [PSAD = PSA (ng/ml)/prostate volume (cc)] h...

journal_title：Cancer

authors： Bretton PR,Evans WP,Borden JD,Castellanos RD

更新日期：1994-12-01 00:00:00

abstract：:The authors studied the expression of c-myc and ras family oncogene products in 43 cases of malignant lymphoma (ML) using the immunoperoxidase method. Unfixed frozen sections of lymph nodes from four patients with Hodgkin's disease and 39 with non-Hodgkin's lymphoma, together with normal lymph nodes, were studied by t...

journal_title：Cancer

authors： Mitani S,Sugawara I,Shiku H,Mori S

更新日期：1988-11-15 00:00:00

abstract：BACKGROUND:Although breast-conserving therapy (tumor excision, axillary node dissection, and postoperative radiation) for women with breast cancer yields survival and local recurrence rates comparable with those of modified radical mastectomy, studies suggest that postoperative radiation leads to capsular contractures ...

journal_title：Cancer

authors： Guenther JM,Tokita KM,Giuliano AE

更新日期：1994-05-15 00:00:00

abstract：BACKGROUND:National Cancer Institute (NCI)/National Comprehensive Cancer Network (NCCN)-designated cancer centers (CCs) offer patients state-of-the-art treatment, but their impact on multiple myeloma (MM) patient outcomes has not been evaluated. METHODS:Adult MM patients diagnosed between 1973 and 2011 were identified...

journal_title：Cancer

authors： Ailawadhi S,Advani P,Yang D,Ghosh R,Swaika A,Roy V,Foran J,Colon-Otero G,Chanan-Khan A

更新日期：2016-02-15 00:00:00

abstract：BACKGROUND:Radiotherapy (RT) has been a risk factor for development of soft tissue sarcomas (STS). The objective of the current study was to quantify the risk of STS after RT and surgery for breast cancer (BCa), assess time trends, and compare long-term survival of patients with RT-associated and non-RT-associated angi...

journal_title：Cancer

authors： Mery CM,George S,Bertagnolli MM,Raut CP

更新日期：2009-09-15 00:00:00

abstract：:The metabolism of 5-fluorouracil (5-FU) was studied in biopsy specimens of primary colorectal cancer and healthy colonic mucosa obtained from previously untreated patients immediately after surgical removal. The conversion of 5-FU to anabolites was measured under saturating substrate (5-FU) and cosubstrate concentrati...

journal_title：Cancer

authors： Peters GJ,van Groeningen CJ,Laurensse EJ,Pinedo HM

更新日期：1991-11-01 00:00:00

abstract：BACKGROUND:Cancer cell expression of costimulatory molecule B7-H1 has been implicated as a potent inhibitor of T-cell-mediated antitumoral immunity. The authors recently reported that B7-H1 is aberrantly expressed in primary renal cell carcinoma (RCC). Blockade of B7-H1, as demonstrated in several murine cancer models,...

journal_title：Cancer

authors： Thompson RH,Gillett MD,Cheville JC,Lohse CM,Dong H,Webster WS,Chen L,Zincke H,Blute ML,Leibovich BC,Kwon ED

更新日期：2005-11-15 00:00:00

abstract：:Estradiol and testosterone levels in the peripheral and ovarian circulation of patients with endometrial cancer and of postmenopausal women were studied. These levels proved to be the same in the two groups. The ovaries of neither group secreted estradiol. The testosterone level in the ovarian circulation of all exami...

journal_title：Cancer

authors： Schenker JG,Weinstein D,Okon E

更新日期：1979-11-01 00:00:00

abstract：:Oat-cell carcinoma of the thymus gland is exceedingly rare as a primary lesion, and only a few cases have been reported. We report a case in which a neoplasm interpreted as an oat-cell carcinoma was intimately associated with and arose in transition from a carcinoid tumor of the thymus. Ultrastructural features of thi...

journal_title：Cancer

authors： Wick MR,Scheithauer BW

更新日期：1982-04-15 00:00:00

abstract：:A retrospective study of all cases of seminoma treated at Roswell Park Memorial Institute from 1970 through 1979 was conducted. Fifty-six evaluable patients treated initially with radiation therapy were seen during this period, and the overall survival rate at an average follow-up period of 52 months was 82%. The surv...

journal_title：Cancer

authors： Huben RP,Williams PD,Pontes JE,Panahon AM,Murphy GP

更新日期：1984-04-01 00:00:00

abstract：:Plasma levels of cyclic AMP and cyclic GMP were determined in 35 guinea pigs for up to 9 days following subcutaneous passage of L2C leukemia cells. Twenty guinea pigs into which normal syngeneic guinea pig thymocytes were passaged served as controls. Cyclic AMP levels in plasma showed little change and were only eleva...

journal_title：Cancer

authors： Wood PJ,Pao G,Cooper A

更新日期：1984-01-01 00:00:00

abstract：:The National Breast and Cervical Cancer Early Detection Program (NBCCEDP) of the Centers for Disease Control and Prevention (CDC) is implemented through cooperative agreements with state health departments, US territories, and tribal health organizations (grantees). Grantees typically contract with clinicians and othe...

journal_title：Cancer

authors： Yancy B,Royalty JE,Marroulis S,Mattingly C,Benard VB,DeGroff A

更新日期：2014-08-15 00:00:00

abstract：BACKGROUND:Activating mutations in RAS are frequently present in patients with acute myeloid leukemia (AML), but their overall prognostic impact is not clear. METHODS:A retrospective analysis was performed to establish the clinical characteristics of patients with RAS-mutated (RAS(mut) ) AML, to analyze their outcome ...

journal_title：Cancer

authors： Kadia TM,Kantarjian H,Kornblau S,Borthakur G,Faderl S,Freireich EJ,Luthra R,Garcia-Manero G,Pierce S,Cortes J,Ravandi F

更新日期：2012-11-15 00:00:00

abstract：BACKGROUND:Pigmented villonodular synovitis (PVNS) (also known as diffuse-type giant cell tumor) and tenosynovial giant cell tumors (TGCT) are rare, usually benign neoplasms that affect the synovium and tendon sheaths in young adults. These tumors are driven by the overexpression of colony stimulating factor-1 (CSF1). ...

journal_title：Cancer

authors： Cassier PA,Gelderblom H,Stacchiotti S,Thomas D,Maki RG,Kroep JR,van der Graaf WT,Italiano A,Seddon B,Dômont J,Bompas E,Wagner AJ,Blay JY

更新日期：2012-03-15 00:00:00

abstract：:To investigate histologic prognostic factors in soft tissue sarcomas (STS), multivariate analysis was performed on 236 patients with complete clinical information. These included 141 males and 95 females with an age range from 1 to 85 years (median, 47.6 years). Histologically, malignant fibrous histiocytoma (33.5%) w...

journal_title：Cancer

authors： Tsujimoto M,Aozasa K,Ueda T,Morimura Y,Komatsubara Y,Doi T

更新日期：1988-09-01 00:00:00

abstract：BACKGROUND:Patients with testicular cancer can be cured by cisplatin-based chemotherapy in many cases. Thus, concern about possible late toxicities of treatment is warranted. METHODS:In this investigation, the absolute number of natural killer (NK) cells according to their CD56+ phenotype, NK cell activity, and antibo...

journal_title：Cancer

authors： Krainer M,Wolf H,Michl I,Wiltschke C,Budinsky A,Kaider A,Kratzik C,Eibl MM,Zielinski CC

更新日期：1995-01-15 00:00:00

abstract：:Twelve Schwann cell tumors (two neurilemomas, six neurofibromas, and four malignant schwannomas), arising in the nasal cavity, paranasal sinuses or nasopharynx, are described. Schwann cell neoplasms only rarely develop in this area. Clinically, these tumors lead to nonspecific symptoms including nasal obstruction epis...

journal_title：Cancer

authors： Perzin KH,Panyu H,Wechter S

更新日期：1982-11-15 00:00:00

abstract：:Fourteen patients with 16 metastatic ostogenic sarcoma lesions were treated with high-dose methotrexate (HDMTX) with citrovorum factor rescue (CFR), adriamycin, and pulse high-dose cyclophosphamide combined with radiation therapy. Thirteen of 16 lesions responded. Responses consisted of relief of pain (6/6 patients) i...

journal_title：Cancer

authors： Rosen G,Tefft M,Martinez A,Cham W,Murphy ML

更新日期：1975-03-01 00:00:00

abstract：BACKGROUND:The objective of the current study was to investigate the effects and the morbidities of single-fraction stereotactic radiation therapy (SRT) for lung tumors. METHODS:A Microtron device was modified to deliver stereotactic irradiation under respiratory gating. Between August 1998 and December 2004, 59 malig...

journal_title：Cancer

authors： Hara R,Itami J,Kondo T,Aruga T,Uno T,Sasano N,Ohnishi K,Kiyozuka M,Fuse M,Ito M,Naoi K,Kohno Y

更新日期：2006-03-15 00:00:00

abstract：:Patients with a localized primary liposarcoma of the extremity who were treated in Memorial Sloan-Kettering Cancer Center between 1968 and 1978 were studied. The prognosis of patients with extremity liposarcoma was analyzed according to histopathologic subtypes. A system of five subtypes was used; well-differentiated,...

journal_title：Cancer

authors： Chang HR,Hajdu SI,Collin C,Brennan MF

更新日期：1989-10-01 00:00:00

abstract：BACKGROUND:Childhood cancer survivors have been reported to be vulnerable to psychiatric morbidities and risky health behavior. Suicides, substance abuse, accidents, and violence as causes of death can be regarded as an extreme manifestation of risky health behavior. In the current study, the authors studied the risk o...

journal_title：Cancer

authors： Korhonen LM,Taskinen M,Rantanen M,Erdmann F,Winther JF,Bautz A,Feychting M,Mogensen H,Talbäck M,Malila N,Ryynänen H,Madanat-Harjuoja L

更新日期：2019-10-15 00:00:00

abstract：:To verify whether analysis of the levels of CA125, carcinoembryonic antigen (CEA), and CA19-9 in the cervical mucus is effective for a detection of cervical adenocarcinomas or not, simultaneous measurement of these three tumor markers in the cervical mucus samples from women without gynecologic disorders, with leiomyo...

journal_title：Cancer

authors： Fujii S,Konishi I,Nanbu Y,Nonogaki H,Kobayashi F,Sagawa N,Mori T,Endo K

更新日期：1988-08-01 00:00:00

abstract：:Two patients fulfilled the clinical and hematologic criteria for B-cell acute lymphoblastic leukemia: the malignant cells had L3 morphology, bore B-cell markers, and carried the specific t(8;14) translocation. The leukemic cells of one patient were tetrasomic for 1q, and those of the other patient showed several separ...

journal_title：Cancer

authors： Morris CM,Fitzgerald PH,Neville MA,Wyld PJ,Beard ME

更新日期：1984-07-01 00:00:00

abstract：BACKGROUND:Fluorescence in situ hybridization (FISH) and immunohistochemistry (IHC) tests are commonly used to assess human epidermal growth factor 2 (HER2) status of tumors in patients with breast cancer. This analysis evaluates the likely cost-effectiveness of expanded retesting to assess HER2 tumor status in women w...

journal_title：Cancer

authors： Garrison LP Jr,Lalla D,Brammer M,Babigumira JB,Wang B,Perez EA

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:The development of malignancies in recipients of a cardiothoracic transplant (CTT)--that is, heart, lung, or heart and lung recipients-is of concern. Cutaneous and lymphoproliferative malignancies comprise the two major groups of malignancies encountered. A small subgroup of patients will develop potentially...

journal_title：Cancer

authors： Veness MJ,Quinn DI,Ong CS,Keogh AM,Macdonald PS,Cooper SG,Morgan GW

更新日期：1999-04-15 00:00:00

abstract：:Identification of BCR-ABL as the defining leukemogenic event in chronic myelogenous leukemia (CML) revolutionized the treatment of the disease. Imatinib, a potent BCR-ABL inhibitor, is the standard of care for the first-line treatment of patients with chronic-phase CML because of its high long-term response rates and ...

journal_title：Cancer

authors： Kantarjian HM,Cortes J,La Rosée P,Hochhaus A

更新日期：2010-03-15 00:00:00

abstract：:Meningeal myeloid metaplasia (MM) is very rarely observed in patients with myelofibrosis. We report the occurrence of meningeal MM causing exophthalmus and fever in a patient with myelofibrosis secondary to polycythemia vera. A computerized tomography (CT) scan showed multiple intracranial and intraorbital enhancing m...

journal_title：Cancer

authors： Landolfi R,Colosimo C Jr,De Candia E,Castellana MA,De Cristofaro R,Trodella L,Leone G

更新日期：1988-12-01 00:00:00

abstract：BACKGROUND:Because medulloblastoma (MB) is rare in adults, the few studies on this condition have been retrospective, and the follow-up has tended to be short. Furthermore, the different therapeutic strategies used in these patients has made it difficult to assess survival rates and prognostic factors. METHODS:In 1989...

journal_title：Cancer

authors： Brandes AA,Franceschi E,Tosoni A,Blatt V,Ermani M

更新日期：2007-11-01 00:00:00

abstract：:The study is a clinicopathologic report on 64 patients with primary adenocarcinoma of the urinary bladder and urachus, with particular reference to important prognostic and therapeutic factors. All tumors exhibited adenocarcinomatous features in at least two thirds of the examined tumor area. Pure forms of the differe...

journal_title：Cancer

authors： Anderström C,Johansson SL,von Schultz L

更新日期：1983-10-01 00:00:00

abstract：:To evaluate the incidence of thrombocytopenia and bleeding among patients with solid tumors treated intensively with chemotherapy, the records of 1274 patients treated between 1972 and 1980 on protocols known to produce significant myelosuppression were reviewed. Three hundred one patients with solid tumors (breast, l...

journal_title：Cancer

authors： Dutcher JP,Schiffer CA,Aisner J,O'Connell BA,Levy C,Kendall JA,Wiernik PH

更新日期：1984-02-01 00:00:00