Abstract:
:Twelve Schwann cell tumors (two neurilemomas, six neurofibromas, and four malignant schwannomas), arising in the nasal cavity, paranasal sinuses or nasopharynx, are described. Schwann cell neoplasms only rarely develop in this area. Clinically, these tumors lead to nonspecific symptoms including nasal obstruction epistaxis, facial pain and swellling, and proptosis, similar to those produced by other neoplasms that involve this area. On radiologic examination, a mass lesion may be identified. Benign Schwann cell tumors may lead to bone erosion, which thus is not necessarily a sign of malignancy. The correct diagnosis of Schwann cell tumor is usually made only when histologic sections are studied. The histologic differentiation between Schwann cell neoplasms and myxomas, fibroblastic tumors, fibrous histiocytomas and fibro-osseous lesions is discussed. Treatment depends upon the type of tumor. Neurilemomas, which usually are encapsulated neoplasms, can be treated by local excision. Neurofibromas may infiltrate extensively, and thus may require an extensive surgical resection; however, functional and cosmetic considerations should be taken into account because neurofibromas, even if incompletely excised, may recur clinically only after many years. Malignant schwannomas tend to be aggressive neoplasms, but because of the anatomy of the area, radical resections leading to complete removal of the tumor cannot always be carried out.
journal_name
Cancerjournal_title
Cancerauthors
Perzin KH,Panyu H,Wechter Sdoi
10.1002/1097-0142(19821115)50:10<2193::aid-cncr282subject
Has Abstractpub_date
1982-11-15 00:00:00pages
2193-202issue
10eissn
0008-543Xissn
1097-0142journal_volume
50pub_type
杂志文章相关文献
CANCER文献大全abstract:BACKGROUND:Patients with locoregional carcinoma of the esophagus or gastroesophageal junction have a poor survival rate after surgery. Preoperative chemotherapy or chemoradiotherapy has not improved the outcome for these patients. Our study was designed to assess the feasibility of preoperative induction combination ch...
journal_title:Cancer
pub_type: 临床试验,杂志文章
doi:10.1002/1097-0142(20010715)92:2<279::aid-cncr1320>
更新日期:2001-07-15 00:00:00
abstract:BACKGROUND:Although >70% of younger women with nonmetastatic breast cancer (BC) received adjuvant chemotherapy, only approximately 15% to 20% of elderly women with BC received chemotherapy. The decision to treat may be associated with nonmedical factors, such as patient, physician, or practice characteristics. In the c...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.24448
更新日期:2009-09-01 00:00:00
abstract:BACKGROUND:To assess the ability of [(18)F]fluorodeoxyglucose (F-18 FDG) positron emission tomography (PET) to predict the viability of residual masses after chemotherapy in patients with metastatic nonseminomatous germ cell tumors (GCT), PET results were compared in a blinded analysis with computed tomography (CT) sca...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.10494
更新日期:2002-05-01 00:00:00
abstract:BACKGROUND:Studies postulate that certain religious beliefs related to medical care influence the end-of-life (EOL) medical decision making and care of patients with advanced cancer. Because to the best of the authors' knowledge no current measure explicitly assesses such beliefs, in the current study the authors intro...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.31946
更新日期:2019-05-01 00:00:00
abstract::The morphologic features, phenotype, and functions of OKM1+ leukemic T-cells were studied. The leukemic T-cells in two patients with chronic lymphocytic leukemia (CLL) had specific features of large granular lymphocytes (LGL), and those in two patients with acute lymphocytic leukemia (ALL) had L2 morphologic character...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19860415)57:8<1507::aid-cncr2820
更新日期:1986-04-15 00:00:00
abstract:BACKGROUND:The objective of the current study was to investigate the effects and the morbidities of single-fraction stereotactic radiation therapy (SRT) for lung tumors. METHODS:A Microtron device was modified to deliver stereotactic irradiation under respiratory gating. Between August 1998 and December 2004, 59 malig...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.21747
更新日期:2006-03-15 00:00:00
abstract::Risk factors associated with local recurrences were analyzed from a series of 3445 clinical Stage I melanoma patients. In single-factor analysis, tumor thickness, ulceration, and increasing age were highly significantly predictive of recurrence (p less than 0.00001). After 5 years of follow-up, local recurrence rates ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19850315)55:6<1398::aid-cncr2820
更新日期:1985-03-15 00:00:00
abstract:BACKGROUND:Aggressive angiomyxoma is an uncommon mesenchymal tumor that preferentially involves the pelvic and perineal regions of females. Since its initial description in 1983, approximately 65 cases have been reported in the English literature. METHODS:The clinical and pathologic features of 29 cases of aggressive ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/(SICI)1097-0142(19960701)78:1<79::AID-CNCR
更新日期:1996-07-01 00:00:00
abstract:BACKGROUND:Intralesional radioimmunotherapy (RAIT) may improve the management of malignant gliomas whose prognosis is, at present, very poor. Current treatment modalities (e.g., surgery, radiotherapy, and chemotherapy) may prolong survival by a few months but cannot prevent tumor recurrence. METHODS:Following one or m...
journal_title:Cancer
pub_type: 临床试验,杂志文章
doi:10.1002/1097-0142(19940201)73:3+<1076::aid-cncr282
更新日期:1994-02-01 00:00:00
abstract:BACKGROUND:Because patients with germ cell tumors expect an additional life span of around 50 years after successful treatment, attention is now focused on potential long term toxicity. Limited data are available on Leydig cell function in long term survivors. METHODS:The authors measured testosterone, sex hormone bin...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(20010401)91:7<1297::aid-cncr1132
更新日期:2001-04-01 00:00:00
abstract::Fifty-eight patients with Dukes' C classification of carcinoma of the large bowel were placed on adjuvant immuno- or chemoimmunotherapy with Bacillus calmette guerin (BCG) or combination of 5-fluorouracil (5-FU) plus BCG following primary and definitive surgery, and were followed for up to 21 months. Of twenty-six pat...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197512)36:6<2421::aid-cncr282036
更新日期:1975-12-01 00:00:00
abstract::Front loading chemotherapy using methotrexate (200 mg/m2) alone or methotrexate (200 mg/m2) with cisplatin (20 mg/m2 daily for 5 days) was used in epidermoid carcinoma of esophagus. Evaluation after two courses showed objective response of 50% or greater in 48% of patients with methotrexate alone. Response rate was in...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19851001)56:7<1502::aid-cncr2820
更新日期:1985-10-01 00:00:00
abstract::Clinical and pharmacokinetic studies were performed regarding the toxicity of methyl 6-[3-(2-chloroethyl)-3-nitrosoureido]-6-deoxy-alpha-D-glucopyranoside (MCNU) with other drugs, in conjunction with a peripheral blood stem cell autograft (PBSCT), for treating 26 children with acute leukemia or lymphoma associated wit...
journal_title:Cancer
pub_type: 临床试验,杂志文章
doi:10.1002/1097-0142(19910401)67:7<1830::aid-cncr2820
更新日期:1991-04-01 00:00:00
abstract:BACKGROUND:Myoepithelial carcinoma, also know as malignant myoepithelioma, is rare in the salivary gland, and its cytologic features have rarely been reported. DESIGN:Four cases of myoepithelial carcinoma with cytology were retrieved from the archives of the Pathology Departments of two academic institutes. In three c...
journal_title:Cancer
pub_type: 杂志文章
doi:
更新日期:2002-02-25 00:00:00
abstract::A 20-year-old man with previously treated lymphoblastic lymphoma, a known T-cell disorder, developed progressive disease despite intensive combination chemotherapy with doxorubicin, vincristine, and prednisone. He was subsequently treated with a 21-day course of intravenous antithymocyte globulin at a dose of approxim...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19820701)50:1<57::aid-cncr282050
更新日期:1982-07-01 00:00:00
abstract:BACKGROUND:A study was undertaken to identify new immunogenic human leukocyte antigen (HLA)-A 2402-restricted epitopes from human papillomavirus (HPV) type 16 E7 protein for immunotherapy against cervical cancer. METHODS:Synthetic overlapping peptides were screened by measuring the frequency of CD8(+) cytotoxic T lymp...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.26468
更新日期:2012-04-15 00:00:00
abstract::Between July 1968 and December 1974, 53 patients with lung cancer were planned for preoperative irradiation and surgery. All patients were considered clinically marginally resectable because of advanced local disease, 4 Stage II patients, with limited pulmonary reserve and 49 Stage III patients. Most patients received...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197805)41:5<2040::aid-cncr282041
更新日期:1978-05-01 00:00:00
abstract:BACKGROUND:Bone morphogenetic proteins (BMP) induce ectopic bone formation in vivo and may play a role in normal bone development. In addition, bone morphogenetic activity, as measured in a bone-forming assay in immunodeficient, athymic nu/nu mice, is present in a proportion of osteosarcomas; this activity, which may b...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19940101)73:1<85::aid-cncr282073
更新日期:1994-01-01 00:00:00
abstract:BACKGROUND:Fludarabine plus busulfan (FB) and fludarabine plus melphalan (FM) are 2 widely used reduced-intensity conditioning (RIC) regimens for allogeneic hematopoietic stem cell transplantation (allo-SCT). METHODS:The current survey compared transplantation outcomes for a cohort of 394 acute myeloid leukemia (AML) ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.29163
更新日期:2015-04-01 00:00:00
abstract:BACKGROUND:Pancreatic-duodenal homeobox 1 (PDX-1) is a transcription factor that regulates embryologic pancreas development and insulin expression in the adult islet; however, it is overexpressed in many types of cancer, including pancreatic cancer. The purpose of this study was to investigate the role of PDX-1 in tumo...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.25629
更新日期:2011-02-15 00:00:00
abstract:BACKGROUND:Shared decision-making (SDM) occurs when a patient partners with their oncologist to integrate personal preferences and values into treatment decisions. A key component of SDM is the elicitation of patient preferences and values, yet little is known about how and when these are elicited, communicated, priori...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.32961
更新日期:2020-08-01 00:00:00
abstract:BACKGROUND:Telomeres are protective structures at the ends of linear chromosomes, regulated by a host of associated proteins. When telomeres become dysfunctional, genomic instability ensues. The vast majority of cells undergo apoptosis, although a rare cell may survive and become tumorigenic. METHODS:The authors used ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.25328
更新日期:2010-09-15 00:00:00
abstract::Sixteen cases of clear cell adenocarcinoma of the cervix and vagina in young women were studied by electron microscopy and the observations were compared with the light microscopic appearance. Ultrastructurally, the neoplastic cells were found to be of the same basic type, regardless of whether light microscopy disclo...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19800401)45:7<1615::aid-cncr2820
更新日期:1980-04-01 00:00:00
abstract:BACKGROUND:Extrapulmonary inflammatory pseudotumor (plasma cell granuloma) is an uncommon lesion in adults and children, and little is known either of its etiology or clinical characteristics. However, it remains a significant source of morbidity to patients and confusion to clinicians. METHODS:Case reports are presen...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/1097-0142(19940301)73:5<1433::aid-cncr2820
更新日期:1994-03-01 00:00:00
abstract::Plasma TSH and thyroxine levels were measured in 74 early breast cancer patients and 53 with advanced disease, 77 patients with cancer arising in other organs and 67 healthy women of similar age. The mean plasma TSH levels were higher in the breast cancer cases than the other two groups; the difference was statistical...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197802)41:2<666::aid-cncr2820410
更新日期:1978-02-01 00:00:00
abstract::Epithelioid sarcoma is an uncommon tumor characterized by its appearance in the distal extremities (especially the forearm, wrist, and ankle), the tendency to recur locally, and high probability of spread to regional lymph nodes. Most patients have been treated surgically, and the potential role of radiation therapy a...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19830915)52:6<1022::aid-cncr2820
更新日期:1983-09-15 00:00:00
abstract::In 1982, more than 125,000 cancer cases in the United States should be preventable. Every physician should advise all patients to eliminate all tobacco use, moderate alcohol use, avoid the use of drugs which are carcinogenic, minimize sun and x-ray exposure, maintain an ideal weight, and follow a "prudent" diet. Secon...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19830615)51:12+<2430::aid-cncr28
更新日期:1983-06-15 00:00:00
abstract::The authors observed the clinical course of 24 women with surgically removed prolactinomas for a mean postoperative interval of 62 months. The frequency of late tumor recurrence and probable factors responsible for the recurrence were investigated. Hyperprolactinemia recurred in 4 of 13 patients with microadenomas (31...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19860615)57:12<2422::aid-cncr282
更新日期:1986-06-15 00:00:00
abstract:BACKGROUND:Trimetrexate is an antifol that differs from methotrexate in ways that may be clinically important. Because methotrexate has activity in advanced bladder cancer, this trial was initiated. METHODS:Ambulatory patients with advanced urothelial carcinoma were treated with the nonclassic antifol trimetrexate at ...
journal_title:Cancer
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1002/1097-0142(19940201)73:3<688::aid-cncr28207
更新日期:1994-02-01 00:00:00
abstract:BACKGROUND:Papanicolaou smear sensitivity for cervical adenocarcinoma (CVCA) is not well established. Also uncertain are the relative contributions to falsely negative diagnoses of sampling, screening, and interpretive errors. METHODS:Papanicolaou smears were identified from all patients at our institutions with biops...
journal_title:Cancer
pub_type: 杂志文章
doi:
更新日期:2001-02-25 00:00:00