PDX-1: demonstration of oncogenic properties in pancreatic cancer.

abstract：:A 58-year-old man with mycosis fungoides developed headache, back pain, and dorsal column signs. A diagnosis of central nervous system (CNS) involvement by mycosis fungoides was made on examination of his spinal fluid. In this patient, cranial and local radiotherapy and aggressive treatment with intrathecal methotrexa...

journal_title：Cancer

authors： Bodensteiner DC,Skikne B

更新日期：1982-09-15 00:00:00

abstract：:The results of assay for estrogen receptor (ER) in the tumor cytosol and thymidine labeling indices (TLI) of 63 primary invasive carcinomas of the breast were analyzed. The ER assay was performed by using dextran-charcoal to adsorb unbound tritiated estradiol-17beta (E2) in cytosol. The TLI was measured as the number ...

journal_title：Cancer

authors： Meyer JS,Rao BR,Stevens SC,White WL

更新日期：1977-11-01 00:00:00

abstract：BACKGROUND:In addition to tumor thickness, several other prognostic parameters have been identified in primary human melanomas. Some are available readily (localization, gender, age, and ulceration). Others must be evaluated with a moderate or even substantial amount of work (mitoses and immunohistochemical markers). T...

journal_title：Cancer

authors： Ostmeier H,Fuchs B,Otto F,Mawick R,Lippold A,Krieg V,Suter L

更新日期：1999-06-01 00:00:00

abstract：:Twenty patients with malignant hepatoma were treated with sequential intraarterial doxorubicin (72-hour continuous infusion) followed by systemic 5-fluorouracil (5-FU) and semustine (methyl CCNU). Objective tumor responses were seen in three patients (15%). The durations of response were 6, 19, and 27+ months, respect...

journal_title：Cancer

authors： O'Connell MJ,Hahn RG,Rubin J,Moertel CG

更新日期：1988-09-15 00:00:00

abstract：BACKGROUND:Because of the small number of cases (five) reported between 1929 and 1969 and a significant increase reported in the decade of the 1970s, the Familial Ovarian Cancer Registry was established in 1981 to study the occurrence of familial ovarian cancer in the United States. METHODS:Any woman (with or without ...

journal_title：Cancer

authors： Piver MS,Baker TR,Jishi MF,Sandecki AM,Tsukada Y,Natarajan N,Mettlin CJ,Blake CA

更新日期：1993-01-15 00:00:00

abstract：BACKGROUND:In the current study, the authors investigated the incidence of moderate to severe chemotherapy-induced peripheral neuropathy (CIPN) for chemotherapy regimens commonly used in current clinical practice for the treatment of patients with early breast cancer. Patient-reported and clinician-assessed CIPN severi...

journal_title：Cancer

authors： Nyrop KA,Deal AM,Reeder-Hayes KE,Shachar SS,Reeve BB,Basch E,Choi SK,Lee JT,Wood WA,Anders CK,Carey LA,Dees EC,Jolly TA,Kimmick GG,Karuturi MS,Reinbolt RE,Speca JC,Muss HB

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:The Centers for Medicare and Medicaid Services (CMS) has released quality measures regarding potentially avoidable hospitalizations visits in the 30 days after receipt of outpatient chemotherapy. This study evaluated the proportions of patients treated by Medicare-reimbursed clinicians and Veterans Health Ad...

journal_title：Cancer

authors： Gidwani-Marszowski R,Faricy-Anderson K,Asch SM,Illarmo S,Ananth L,Patel MI

更新日期：2020-07-15 00:00:00

abstract：:The two cancers specific to women for which substantial research on their relationship to exogenous estrogens has been reported are endometrial cancer and breast cancer. With the former, the link to estrogen use is well established. The estrogen use patterns associated with increased risk of endometrial cancer are cha...

journal_title：Cancer

authors： Hulka BS

更新日期：1987-10-15 00:00:00

abstract：:Patients with unresectable, previously untreated head and neck cancer were given cis-diamminedichloroplatinum (II) (DDP), 3 mg/kg, with mannitol diuresis (day 1), followed by a continuous infusion of bleomycin, 0.25 mg/kg/day, days 3 through 10, after an initial loading dose of 0.25 mg/kg by rapid IV injection on day ...

journal_title：Cancer

authors： Randolph VL,Vallejo A,Spiro RH,Shah J,Strong EW,Huvos AG,Wittes RE

更新日期：1978-02-01 00:00:00

abstract：:Of 209 Hodgkin's disease patients treated at least 6 months with a five-drug combination of induction chemotherapy and having a complete remission, four patients developed acute myelogenous leukemia (AML) as a second malignant neoplasm. The overall relative risk for development of AML is 185.0 (P less than 0.05) and t...

journal_title：Cancer

authors： Bartolucci AA,Liu C,Durant JR,Gams RA

更新日期：1983-12-15 00:00:00

abstract：:A 22-micron glass microsphere called TheraSphere (Theragenics Corp., Atlanta, GA) has been developed in which yttrium 89 oxide is incorporated into the glass matrix and is activated by neutron bombardment to form the beta-emitting isotope yttrium 90 (Y 90) before using the spheres as radiotherapeutic vehicles. The inj...

journal_title：Cancer

authors： Wollner I,Knutsen C,Smith P,Prieskorn D,Chrisp C,Andrews J,Juni J,Warber S,Klevering J,Crudup J

更新日期：1988-04-01 00:00:00

abstract：:Interest in the elderly population, persons 65 years of age or older, as a target group for cancer control has not been great. Age recommendations rarely are made for prevention and early detection of cancer for elderly persons. However, cancer incidence and mortality rates are known to rise rapidly with increasing ag...

journal_title：Cancer

authors： Yancik R,Kessler L,Yates JW

更新日期：1988-10-15 00:00:00

abstract：:The role of palliative radiation treatment of prostate cancer is well recognized. Appreciation of the value of definitive radiation therapy in management of locally advanced prostate cancer is increasing. Optimal management requires careful patient selection with multidiscipline evaluation to provide accurate grading ...

journal_title：Cancer

authors： Taylor WJ

更新日期：1977-02-01 00:00:00

abstract：:Twenty-two cases of breast tumor with infiltrating lobular carcinoma were studied. Thirteen showed the classic single-file pattern as a sole component, and 6 as a predominant pattern; the less common confluent pattern was found in 3 instances as a predominant component. Mucin secretion was evidenced in 59% of the prim...

journal_title：Cancer

authors： Van Bogaert LJ,Maldague P

更新日期：1980-03-01 00:00:00

abstract：BACKGROUND:Allelic deletions are frequent genetic alterations in patients with hepatocellular carcinoma (HCC). METHODS:To evaluate the allelic losses on chromosome 8p in HCC patients and define their clinicopathologic significance, we performed high-density allelotyping on 8p in 60 patients with HCC and analyzed the c...

journal_title：Cancer

authors： Chan KL,Lee JM,Guan XY,Fan ST,Ng IO

更新日期：2002-06-15 00:00:00

abstract：BACKGROUND:Antithymocyte globulin (ATG) is an important component of conditioning regimens to prevent severe graft-versus-host disease (GVHD) in patients undergoing unmanipulated, haploidentical stem cell transplantation (haplo-SCT). However, to the authors' knowledge, the optimal dose of ATG is unknown. METHODS:In th...

journal_title：Cancer

authors： Chang YJ,Wang Y,Mo XD,Zhang XH,Xu LP,Yan CH,Chen H,Chen YH,Chen Y,Han W,Wang FR,Wang JZ,Liu KY,Huang XJ

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:Partial splenic embolization (PSE) has been used to improve hematologic parameters related to hypersplenism. The purpose of this study was to review our institutional experience with PSE for cancer patients with thrombocytopenia because of splenic sequestration precluding the administration of systemic thera...

journal_title：Cancer

authors： Kauffman CR,Mahvash A,Kopetz S,Wolff RA,Ensor J,Wallace MJ

更新日期：2008-05-15 00:00:00

abstract：BACKGROUND:The benefits of an active lifestyle after a breast cancer diagnosis are well recognized, but the majority of survivors are insufficiently active. The ACTIVATE Trial examined the efficacy of an intervention (use of the Garmin Vivofit 2 activity monitor coupled with a behavioral feedback and goal-setting sessi...

journal_title：Cancer

authors： Lynch BM,Nguyen NH,Moore MM,Reeves MM,Rosenberg DE,Boyle T,Vallance JK,Milton S,Friedenreich CM,English DR

更新日期：2019-08-15 00:00:00

abstract：:Multivariate statistical analyses are used to evaluate a wide range of factors in predicting relapse and survival for 429 children enrolled in the National Wilms' Tumor Study. Anaplastic or sarcomatous histology, specimen weight over 250 grams, positive regional lymph nodes, treatment with only a single drug and age o...

journal_title：Cancer

authors： Breslow NE,Palmer NF,Hill LR,Buring J,D'Angio GJ

更新日期：1978-04-01 00:00:00

abstract：:The cases of 189 patients treated at the Surgery Service for gastric carcinoma from January 1960 to December 1978 and followed until April 1984 were reviewed in terms of evolutive behavior. Correlations between sex, age, duration of symptoms, site of tumors, lymph node metastases, stage of tumors, operability, resecta...

journal_title：Cancer

authors： Ziliotto A Jr,Kunzle JE,De Souza A,Colicchio-Filho O

更新日期：1987-02-15 00:00:00

abstract：:A hybrid radiofrequency heating system previously reported to produce highly focused heating patterns at less than or equal to 10 cm depth in phantom models was utilized to selectively heat hypervascular, heat resistant rabbit V-2 tumors implanted in the left hindlimb. Spheroidal heating patterns 3 to 4 cm in diameter...

journal_title：Cancer

authors： Boddie AW Jr,Merritt DR,Yamanashi W,Frazer JW,McBride CM,Martin RG

更新日期：1985-03-15 00:00:00

abstract：BACKGROUND:Because patients with germ cell tumors expect an additional life span of around 50 years after successful treatment, attention is now focused on potential long term toxicity. Limited data are available on Leydig cell function in long term survivors. METHODS:The authors measured testosterone, sex hormone bin...

journal_title：Cancer

authors： Gerl A,Mühlbayer D,Hansmann G,Mraz W,Hiddemann W

更新日期：2001-04-01 00:00:00

abstract：BACKGROUND:Breast cancers that are negative for estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2) (triple negative [TN]) have been associated with high-grade histology, aggressive clinical behavior, and poor survival. It has been determined that breast cancers that ...

journal_title：Cancer

authors： Brown M,Tsodikov A,Bauer KR,Parise CA,Caggiano V

更新日期：2008-02-15 00:00:00

abstract：BACKGROUND:This study was performed to determine the incidence of central venous device-related blood stream infection and thrombosis in patients treated with moderate dose continuous-infusion interleukin-2 (IL-2). METHODS:The records of 160 consecutive patients treated at the University of Wisconsin Hospital and Clin...

journal_title：Cancer

authors： Eastman ME,Khorsand M,Maki DG,Williams EC,Kim K,Sondel PM,Schiller JH,Albertini MR

更新日期：2001-02-15 00:00:00

abstract：BACKGROUND:Reports on lymphoid malignancy and its treatment in children infected with human immunodeficiency virus (HIV) are limited. METHODS:Antibodies to Epstein-Barr virus (EBV) were detected by indirect immunofluorescence. DNA was extracted from peripheral blood lymphocytes or biopsy specimens. Polymerase chain re...

journal_title：Cancer

authors： Nadal D,Caduff R,Frey E,Hassam S,Zimmermann DR,Seigneurin JM,Plüss HJ,Seger RA

更新日期：1994-01-01 00:00:00

abstract：:With increasing numbers of survivors from cancer at a young age, the issue of fertility preservation has assumed greater importance. This review describes normal ovarian and testicular function and summarizes what is known about the effect of chemotherapy and radiotherapy on the gonads and uterus. All young patients w...

journal_title：Cancer

authors： Wallace WH

更新日期：2011-05-15 00:00:00

abstract：BACKGROUND:In the United States, incidence rates for malignant tumors of the uterine corpus are lower among blacks than among whites, whereas mortality rates are higher among blacks. Reasons for the higher level of mortality among blacks have been debated. METHODS:Using data from the Surveillance, Epidemiology, and En...

journal_title：Cancer

authors： Sherman ME,Devesa SS

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND:US breast cancer mortality is declining, but thousands of women still die each year. METHODS:Two established simulation models examine 6 strategies that include increased screening and/or treatment or elimination of obesity versus continuation of current patterns. The models use common national data on inci...

journal_title：Cancer

authors： Mandelblatt J,van Ravesteyn N,Schechter C,Chang Y,Huang AT,Near AM,de Koning H,Jemal A

更新日期：2013-07-15 00:00:00

abstract：:A case of thymoma in a 12-year-old boy is presented. The patient had a history of thymic irradiation in infancy, and a family history of leukemia. The mass was readily resected and the patient is well 10 years later. The tumor contained an unusual admixture of normal thymic tissue with the neoplastic epithelial elemen...

journal_title：Cancer

authors： Chatten J,Katz SM

更新日期：1976-02-01 00:00:00

abstract：:The hematologic factors of 16 female patients with breast carcinoma who had received adjuvant chemotherapy with L-phenylalanine-based programs for two years were compared with those for 13 normal female volunteers of similar age. The findings include significant suppression of the mean hemoglobin level, of leukocyte c...

journal_title：Cancer

authors： Corder MP,Jochimsen PR

更新日期：1982-06-15 00:00:00