Combination therapy of advanced head and neck cancer: induction of remissions with diamminedichloroplatinum (II), bleomycin and radiation therapy.

abstract：BACKGROUND:The National Quality Forum endorses the recommendation of examining at least 12 lymph nodes (LNs) from colorectal cancer (CRC) specimens. However, heterogeneity in LN harvest exists. The objective of this study was to investigate the clinicopathologic factors that influence LN yield. METHODS:The authors use...

journal_title：Cancer

authors： Chou JF,Row D,Gonen M,Liu YH,Schrag D,Weiser MR

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:MicroRNAs (miRNAs) play a crucial role in carcinogenesis; however, it largely remains unclear whether miRNAs in gastric juice, which is specific for gastric tissues, can be used as biomarkers for gastric cancer. The objective of the current study was to investigate the feasibility of using gastric juice miRN...

journal_title：Cancer

authors： Cui L,Zhang X,Ye G,Zheng T,Song H,Deng H,Xiao B,Xia T,Yu X,Le Y,Guo J

更新日期：2013-05-01 00:00:00

abstract：:From January, 1973, to June, 1976, 226 patients with palpable ovarian masses were evaluated preoperatively by lymphography. Histology showed 166 cases of malignant epithelial tumors, 26 benign tumors, and 34 malignant special tumors (not included in this report). Furthermore, the group of patients included 99 recurren...

journal_title：Cancer

authors： Musumeci R,Banfi A,Bolis G,Candiani GB,De Palo G,Di Re F,Lucina L,Lattuada A,Mangioni C,Mattioli G,Natale N

更新日期：1977-10-01 00:00:00

abstract：BACKGROUND:Poor enrollment of adolescents and young adults (AYAs) (ages 15-39 years) onto cancer clinical trials (CCTs) may contribute to inferior survival gains compared with children. In this study, the authors assessed whether differences in CCT availability would explain lower CCT enrollment for early AYAs (eAYAs) ...

journal_title：Cancer

authors： Thomas SM,Malvar J,Tran H,Shows J,Freyer DR

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Amplification of the N-myc oncogene is associated with adverse outcomes in the common childhood tumor, neuroblastoma. Because the transforming properties of Myc are related to its ability to modulate gene expression, the authors used cDNA microarrays to identify potential Myc target genes. METHODS:Expressio...

journal_title：Cancer

authors： Raetz EA,Kim MK,Moos P,Carlson M,Bruggers C,Hooper DK,Foot L,Liu T,Seeger R,Carroll WL

更新日期：2003-08-15 00:00:00

abstract：:The clinical and pathologic features of eight infants with monocytic leukemia are reviewed. The children were all aged 12 months or less at diagnosis and had a high incidence of extramedullary features, skin infiltration being particularly common. The diagnosis was established by conventional morphologic and cytochemi...

journal_title：Cancer

authors： Darbyshire PJ,Smith JH,Oakhill A,Mott MG

更新日期：1985-10-01 00:00:00

abstract：BACKGROUND:Insular thyroid carcinoma was described originally as a tumor with aggressive behavior. However, whether a predominant insular component is an independent factor for poor prognosis is unclear. METHODS:The authors compared the clinical behavior of tumors in three groups of patients with thyroid carcinoma--13...

journal_title：Cancer

authors： Pellegriti G,Giuffrida D,Scollo C,Vigneri R,Regalbuto C,Squatrito S,Belfiore A

更新日期：2002-11-15 00:00:00

abstract：:To assess the importance of radiation dose fraction size in the treatment of malignant melanomas, the records of 48 patients (83 sites) treated at Tufts-New England Medical Center from 1971 to 1979 have been retrospectively reviewed. During this period, the dose fractionation schemes evolved from standard fraction siz...

journal_title：Cancer

authors： Strauss A,Dritschilo A,Nathanson L,Piro AJ

更新日期：1981-03-15 00:00:00

abstract：BACKGROUND:Recommendations for pretreatment evaluation and treatment of cervical cancer have significantly evolved over the last decade because of the results of multiple randomized studies comparing the addition of platin-based chemoradiation as well as the widespread dissemination and use of imaging modalities. This ...

journal_title：Cancer

authors： Trimble EL,Harlan LC,Gius D,Stevens J,Schwartz SM

更新日期：2008-08-15 00:00:00

abstract：BACKGROUND:This study was performed to evaluate the effect of positive margins, Gleason grade, and capsular penetration on progression after radical prostatectomy. METHODS:The authors followed 507 men with totally embedded retropubic prostatectomy specimens performed for clinical Stages A and B prostate cancer for a m...

journal_title：Cancer

authors： Epstein JI,Pizov G,Walsh PC

更新日期：1993-06-01 00:00:00

abstract：:The effect of cyclophosphamide (CY) on ovarian function was studied in patients with breast cancer receiving prolonged daily administration of this agent (100 mg/day) after radical surgery. Out of 18 premenopausal patients that received 8.4-39.9 g CY, 15 developed permanent amenorrhea. The average dose given before th...

journal_title：Cancer

authors： Koyama H,Wada T,Nishizawa Y,Iwanaga T,Aoki Y

更新日期：1977-04-01 00:00:00

abstract：:In a 3 1/2 year cytogenetic study of 107 leukemia patients diagnosed in childhood and adloescence, 8 presented with chronic myelogenous leukemia (CML). Seven of the 8 had chromosomal abnormalities. Six had the Ph1 chromosome; 5 had the usual 9;22 translocation. Two patients had involvement with chromosome 15; one had ...

journal_title：Cancer

authors： Hays T,Morse H,Peakman D,Rose B,Robinson A

更新日期：1979-07-01 00:00:00

abstract：BACKGROUND:Tobacco assessment and cessation support are not routinely included in cancer care. An automated tobacco assessment and cessation program was developed to increase the delivery of tobacco cessation support for cancer patients. METHODS:A structured tobacco assessment was incorporated into the electronic heal...

journal_title：Cancer

authors： Warren GW,Marshall JR,Cummings KM,Zevon MA,Reed R,Hysert P,Mahoney MC,Hyland AJ,Nwogu C,Demmy T,Dexter E,Kelly M,O'Connor RJ,Houstin T,Jenkins D,Germain P,Singh AK,Epstein J,Dobson Amato KA,Reid ME

更新日期：2014-02-15 00:00:00

abstract：:A series of experiments was devised to determine possible modifying effects of stress, aspirin, and sodium taurocholate on the activity of N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) in the Buffalo rat stomach. MNNG is a well known, direct-reacting carcinogen, and has been a reliable agent for the experimental product...

journal_title：Cancer

authors： Cohen A,Geller SA,Horowitz I,Toth LS,Werther JL

更新日期：1984-03-01 00:00:00

abstract：BACKGROUND:The ability of screening mammography programs serving women of different socioeconomic status (SES) to diagnose early stage breast carcinoma in a comparably effective fashion has been questioned. METHODS:Results of screening 50,653 women of lower SES were compared with those of screening 45,923 more socioec...

journal_title：Cancer

authors： Dershaw DD,Loring L,True SJ,Momrow DC,Liberman L,Morris EA

更新日期：1998-05-01 00:00:00

abstract：BACKGROUND:A higher total dose of radiation therapy administered in fractionated lower individual doses twice daily (hyperfractionated radiation therapy) has been reported to improve survival for children with brain stem gliomas. However, this higher dose of radiation therapy may cause more sequelae. METHOD:Eighty-eig...

journal_title：Cancer

authors： Packer RJ,Zimmerman RA,Kaplan A,Wara WM,Rorke LB,Selch M,Goldwein J,Allen JA,Boyett J,Albright AL

更新日期：1993-04-15 00:00:00

abstract：BACKGROUND:Patients with locoregional carcinoma of the esophagus or gastroesophageal junction have a poor survival rate after surgery. Preoperative chemotherapy or chemoradiotherapy has not improved the outcome for these patients. Our study was designed to assess the feasibility of preoperative induction combination ch...

journal_title：Cancer

authors： Ajani JA,Komaki R,Putnam JB,Walsh G,Nesbitt J,Pisters PW,Lynch PM,Vaporciyan A,Smythe R,Lahoti S,Raijman I,Swisher S,Martin FD,Roth JA

更新日期：2001-07-15 00:00:00

abstract：BACKGROUND:Sunitinib and sorafenib are small-molecule tyrosine kinase inhibitors (TKI) with antitumor activity in advanced renal cell carcinoma. A retrospective study was conducted to assess the response of renal cell carcinoma to sequential treatment with these two agents. METHODS:Tumor response was evaluated by usin...

journal_title：Cancer

authors： Dudek AZ,Zolnierek J,Dham A,Lindgren BR,Szczylik C

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Historically, estrogen receptor (ER) determinations have been made by the ligand-binding assay of tumor homogenates, primarily by the dextran-coated charcoal method (DCC). Immunocytochemical assays (ICA) for ER are more recent and have been executed mostly on frozen sections with the monoclonal antibody H222...

journal_title：Cancer

authors： Pertschuk LP,Feldman JG,Kim YD,Braithwaite L,Schneider F,Braverman AS,Axiotis C

更新日期：1996-06-15 00:00:00

abstract：:Adrenal cortical carcinoma is an uncommon neoplasm in children. Only a handful of congenital adrenal cortical carcinoma cases have been described. A newborn who had metastatic adrenal cortical carcinoma (skin metastases and cerebral lesions) is described. This patient underwent surgical resection of the right adrenal ...

journal_title：Cancer

authors： Saracco S,Abramowsky C,Taylor S,Silverman RA,Berman BW

更新日期：1988-08-01 00:00:00

abstract：:This study concerns 75 patients with squamous cell carcinoma of the oral cavity who were patients at the Gustave-Roussy Institute between December 1966 and July 1973. These patients were divided into two groups. The first group was comprised of 39 patients who underwent elective radical neck dissection; nodal involvem...

journal_title：Cancer

authors： Vandenbrouck C,Sancho-Garnier H,Chassagne D,Saravane D,Cachin Y,Micheau C

更新日期：1980-07-15 00:00:00

abstract：BACKGROUND:Microsatellite instability (MIN) appears to be a novel molecular mechanism in carcinogenesis and is believed to reflect multiple replication errors. The authors analyzed MIN in de novo acute leukemia and its association with expression of the human MSH3 (hMSH3) gene and point mutations of the N-ras gene. The...

journal_title：Cancer

authors： Tanosaki S,Inokuchi K,Shimada T,Dan K

更新日期：1998-08-01 00:00:00

abstract：:Mammary carcinomas have been induced by 3.5 Gy whole-body gamma radiation administered at age 40 to 50 days to virgin female Sprague-Dawley rats. In 142 irradiated controls carcinoma incidence averaged 7.8% in survivors observed less than 300 days and 38.3% of those surviving longer (P less than 0.001 by t test). Mamm...

journal_title：Cancer

authors： Lemon HM,Kumar PF,Peterson C,Rodriguez-Sierra JF,Abbo KM

更新日期：1989-05-01 00:00:00

abstract：BACKGROUND:The clinical significance of atypical glandular cells of undetermined significance (AGUS) remains poorly understood, and patient management is not standardized. The authors evaluated the rate, qualification, and follow-up (FU) findings of AGUS patients. METHODS:Computerized records from the authors' institu...

journal_title：Cancer

authors： Soofer SB,Sidawy MK

更新日期：2000-08-25 00:00:00

abstract：BACKGROUND:Childhood cancer is a highly curable disease when timely diagnosis and appropriate therapy are provided. A negative impact of the coronavirus disease 2019 (COVID-19) pandemic on access to care for children with cancer is likely but has not been evaluated. METHODS:A 34-item survey focusing on barriers to ped...

journal_title：Cancer

authors： Saab R,Obeid A,Gachi F,Boudiaf H,Sargsyan L,Al-Saad K,Javakhadze T,Mehrvar A,Abbas SS,Abed Al-Agele YS,Al-Haddad S,Al Ani MH,Al-Sweedan S,Al Kofide A,Jastaniah W,Khalifa N,Bechara E,Baassiri M,Noun P,El-Houdzi J,K

更新日期：2020-09-15 00:00:00

abstract：:Hepatoblastoma differs from the adult type of hepatoma in clinical and pathologic features. The ratio of fucosylation of serum alpha-fetoprotein (AFP) was determined in seven patients with hepatoblastoma and in 21 infants and children with otherwise elevated serum AFP, using the improved technique of lentil agglutinin...

journal_title：Cancer

authors： Tsuchida Y,Honna T,Fukui M,Sakaguchi H,Ishiguro T

更新日期：1989-06-01 00:00:00

abstract：:Doubling times were estimated for 15 breast carcinomas in 13 patients, and were found to be between 42 and 397 days with the average at 211 days. The mean lead time at mean growth rate from the average size of 44 preclinical to the average size of 118 clinical tumors was estimated to be 3 years. This period may be con...

journal_title：Cancer

authors： Lundgren B

更新日期：1977-10-01 00:00:00

abstract：:Reported are six cases of meningocerebral astrocytomas attached to dura, involving the superficial cortex, in infants under 1 year of age. They represent 1.25% of 483 intracranial tumors in infancy studied at the Children's Hospital in the last 12 years. Five were located in the frontal lobes, with variable extension ...

journal_title：Cancer

authors： Taratuto AL,Monges J,Lylyk P,Leiguarda R

更新日期：1984-12-01 00:00:00

abstract：:Epidermoid cancer accounts for 81% of the malignancies of the vulva. Although the etiology has not been delineated, chronic vulvitis is associated with cancer in almost one-third of the patients. The staging system should utilize the most precise and accurate parameters delineated for improved treatment. A new staging...

journal_title：Cancer

authors： Krupp P,Bohm JW,Lee FY,Collins JH

更新日期：1976-07-01 00:00:00

abstract：BACKGROUND:The association of community factors and outcomes after hematopoietic cell transplantation (HCT) has not been comprehensively described. Using the County Health Rankings and Roadmaps (CHRR) and the Center for International Blood and Marrow Transplant Research (CIBMTR), this study evaluated the impact of comm...

journal_title：Cancer

authors： Hong S,Brazauskas R,Hebert KM,Ganguly S,Abdel-Azim H,Diaz MA,Beattie S,Ciurea SO,Szwajcer D,Badawy SM,Gratwohl AA,LeMaistre C,Aljurf MDSM,Olsson RF,Bhatt NS,Farhadfar N,Yared JA,Yoshimi A,Seo S,Gergis U,Beitinjane

更新日期：2021-02-15 00:00:00