Abstract:
:Epidemiology and prognosis were analyzed in a consecutive, population-based series of 137 patients with malignant fibrous histiocytoma of soft tissue in the extremities and trunk wall, with a complete follow-up of minimum 3 years. All but one patient were treated by surgery in 28 cases combined with adjuvant radiotherapy or chemotherapy. The annual incidence was 0.42/10(5). The ratio men to women was 1.1. The median age was 64 years (range, 22 to 87 years). The thigh was the most common location. The median size was 6 cm. Superficial tumors constituted 43% and were smaller than deep-seated tumors. Eighty-three tumors were storiform-pleomorphic, 53 were myxoid, and one was of inflammatory type. The myxoid tumors were smaller and more often superficial. The cumulative 5-year survival rate for all patients was 0.7, but differed markedly between the histologic types; it was 1.0 in patients with myxoid tumors and 0.5 in patients with storiform-pleomorphic tumors. In the 77 patients with storiform-pleomorphic tumors without metastases at presentation, only tumor size larger than 10 cm and tumor necrosis independently impaired survival. The 23 patients who had none of these risk factors had a 5-year survival rate of 0.8.
journal_name
Cancerjournal_title
Cancerauthors
Rööser B,Willén H,Gustafson P,Alvegård TA,Rydholm Adoi
10.1002/1097-0142(19910115)67:2<499::aid-cncr28206subject
Has Abstractpub_date
1991-01-15 00:00:00pages
499-505issue
2eissn
0008-543Xissn
1097-0142journal_volume
67pub_type
杂志文章相关文献
CANCER文献大全abstract:BACKGROUND:Assessment of the responses of osteosarcoma patients to preoperative chemotherapy is of clinical importance. The purpose of this study was to estimate the accuracy of angiography and thallium-201 scintigraphy, compared with histology, in assessing the responses of patients with osteosarcoma to preoperative c...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/(sici)1097-0142(19990915)86:6<949::aid-cnc
更新日期:1999-09-15 00:00:00
abstract::To investigate histologic prognostic factors in soft tissue sarcomas (STS), multivariate analysis was performed on 236 patients with complete clinical information. These included 141 males and 95 females with an age range from 1 to 85 years (median, 47.6 years). Histologically, malignant fibrous histiocytoma (33.5%) w...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19880901)62:5<994::aid-cncr28206
更新日期:1988-09-01 00:00:00
abstract:BACKGROUND:This study was conducted to review the efficacy and safety of oral bisphosphonates for the treatment of bone metastases in cancer patients. METHODS:Available published clinical studies of oral bisphosphonates in bone metastases from 1980 to the present were identified through a MEDLINE search and from liter...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:
更新日期:2000-01-01 00:00:00
abstract::A 52-year-old female presented with an extensive retroperitoneal sarcoma and intraluminal inferior vena caval extension. Presumably during resection, embolization of a tumor fragment occurred to the right pulmonary hilum. The patient was asymptomatic for 16 months until a right hilar mass developed on a follow-up ches...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19800915)46:6<1492::aid-cncr2820
更新日期:1980-09-15 00:00:00
abstract::Twenty-two patients seen between 1975 and 1988 were analyzed who had surgical attempts to cure locally advanced prostate cancer by exenterative procedures or salvage surgery for radiation recurrent disease. Twelve patients (Group I) underwent either a salvage cystoprostatectomy or perineal prostatectomy for radiorecur...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19910915)68:6<1265::aid-cncr2820
更新日期:1991-09-15 00:00:00
abstract:BACKGROUND:To the authors' knowledge, the potential prognostic value of DNA ploidy in vulvar melanoma has not been evaluated in previous series. METHODS:Clinical data and follow-up information were retrieved from the hospital records of 75 patients treated from 1956 to 1987. Histopathologic specimens were reviewed for...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19950101)75:1<72::aid-cncr282075
更新日期:1995-01-01 00:00:00
abstract:BACKGROUND:Ovarian dysplasia has been defined by histologic and morphometric studies focusing on architectural and nuclear profile changes. A new technique is used to enhance the accuracy of this diagnosis by a quantitative evaluation of the nuclear texture that represents the nuclear chromatin pattern on which convent...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19931201)72:11<3253::aid-cncr282
更新日期:1993-12-01 00:00:00
abstract:BACKGROUND:Prognostic implications of overexpression of the HER-2 gene in nonsmall cell lung carcinoma (NSCLC) are a matter of controversy. Many conflicting results have been reported from different laboratories. METHODS:A metaanalysis of published studies was performed for this quantitative review of the effects of H...
journal_title:Cancer
pub_type: 杂志文章,meta分析
doi:10.1002/cncr.20957
更新日期:2005-05-01 00:00:00
abstract:BACKGROUND:There is little information on the function of dendritic cells in women with human papillomavirus (HPV)-related cervical squamous intraepithelial lesions (SILs). In the current study the functions of dendritic cells in the development of T-cell immunity in women with cervical SILs were assessed. METHODS:The...
journal_title:Cancer
pub_type: 杂志文章,多中心研究
doi:10.1002/cncr.22092
更新日期:2006-09-01 00:00:00
abstract:BACKGROUND:Radiation therapy plays a major role in the management of patients with either locally recurrent or metastatic carcinoma of the prostate. RESULTS:In 23 patients with isolated postprostatectomy local recurrences treated with doses of 60-65 Gy, 17 (74%) had tumor control, and 45% survived relapse-free for 5 y...
journal_title:Cancer
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1002/1097-0142(19930201)71:3+<1110::aid-cncr282
更新日期:1993-02-01 00:00:00
abstract:BACKGROUND:This review was done to assess the outcomes and patterns of recurrence in a group of patients with Stage III endometrial carcinoma that might help guide adjuvant therapy. METHODS:A retrospective review was performed of 105 patients treated from 1970-1990 at three institutions. All patients underwent abdomin...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19930601)71:11<3697::aid-cncr282
更新日期:1993-06-01 00:00:00
abstract:BACKGROUND:In the current study, the authors propose the quantitative Gleason score (qGS), a modification of the current Gleason grading system for prostate cancer, based on the weighted average of Gleason patterns present in the pathology specimen. They hypothesize that the qGS can improve prostate cancer risk stratif...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.27670
更新日期:2012-12-15 00:00:00
abstract:BACKGROUND:TRAIL (tumor necrosis factor related apoptosis-inducing ligand) is involved in tumor immune surveillance and, thus, may be a potential cancer therapy. TRAIL expression in the tumor microenvironment has been shown to impact cancer survival in multiple tumor types, including ovarian cancer. We studied TRAIL ex...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.25504
更新日期:2011-03-15 00:00:00
abstract:BACKGROUND:Recent evidence has identified pre-existing type 2 diabetes mellitus (T2DM) as a risk factor for the development of PAC, but relatively little is known about its effects on survival. Our aim was to determine the effect of varying durations of pre-existing T2DM on survival in patients with PAC. METHODS:We co...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.27731
更新日期:2013-01-15 00:00:00
abstract::From 1977, 29 patients with inoperable non-small cell lung carcinoma due to locally far-advanced disease underwent lung resection after receiving two to eight courses of chemotherapy. After the surgery was performed, three additional courses of chemotherapy were given. The overall median survival from onset of the che...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19860201)57:3<630::aid-cncr28205
更新日期:1986-02-01 00:00:00
abstract::Fiberoptic endoscopic examination and biopsy of the nasopharynx was done in 130 patients as a prospective study. They all had elevated titers of antibodies against the viral capsid antigen of Epstein-Barr virus but no symptoms or signs of nasopharyngeal carcinoma. Each underwent a biopsy from six fixed sites in the na...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19910615)67:12<3127::aid-cncr282
更新日期:1991-06-15 00:00:00
abstract:BACKGROUND:Although studies comparing conventional imaging modalities with (18)F-fluorodeoxyglucose positron emission tomography ((18)F-FDG-PET) for the detection of lymphoma and although the relations between (18)F-FDG-PET and histologic types were reported previously, most studies were not systematic and involved rel...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.22807
更新日期:2007-08-01 00:00:00
abstract:BACKGROUND:Polymorphic reticulosis, a type of lethal midline granuloma (LMG), has been referred to as nasal T-cell lymphoma (NTL) because of its proliferating cells' positive reactivity to anti-T-lymphocyte antibodies. Recently, several studies have suggested that proliferating cells in NTL may be natural killer (NK) i...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19950201)75:3<894::aid-cncr28207
更新日期:1995-02-01 00:00:00
abstract:BACKGROUND:Ovarian surface epithelial cells are positionally organized as a single cell layer by a sheet of basement membrane. It is believed that the contact of the ovarian surface epithelial cells with the basement membrane regulates cell growth and ensures the organization of the epithelium. Disabled-2 (Dab2), a sig...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.10870
更新日期:2002-10-15 00:00:00
abstract::The clinical, patient-oriented focus of medicine and psychology is contrasted with the epidemiologic (public health) approach in assessing the role of life-style factors and health promotion in cancer research. The unifying host-agent-environment epidemiologic paradigm is applied to contemporary cancer prevention issu...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/1097-0142(19910201)67:3+<808::aid-cncr2820
更新日期:1991-02-01 00:00:00
abstract::Between July 1951 and January 1984, 14 female patients (11 black and three white; average age, 58 years) were treated for primary urethral carcinoma. Five patients had radical surgery, six received preoperative radiotherapy (2000 cGy in five fractions) followed by anterior exenteration, and three had definitive radiot...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19880701)62:1<54::aid-cncr282062
更新日期:1988-07-01 00:00:00
abstract:BACKGROUND:In a randomized Phase II study, the authors evaluated the activity and toxicity of the new cisplatin, doxorubicin, and mitomycin C (PAM) combination, that includes cisplatin (P) instead of 5-fluorouracil as in the 5-fluorouracil, doxorubicin, and mitomycin C (FAM) combination, in patients with advanced gastr...
journal_title:Cancer
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1002/(SICI)1097-0142(19960115)77:2<245::AID-CNC
更新日期:1996-01-15 00:00:00
abstract::The radionuclide, gallium-67, accumulates in a wide variety of neoplastic and inflammatory lesions. Diffuse bilateral lung localization of 67Ga occurred in two cases of interstitial pneumonitis associated with bleomycin therapy. Clinical symptoms and laboratory evaluation of pulmonary status correlated with scintigrap...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.2820360906
更新日期:1975-12-01 00:00:00
abstract:BACKGROUND:Breast carcinoma is one of the leading causes of excess mortality rates in Harlem, an inner-city neighborhood with the highest mortality rates and worst life expectancy in New York City. This study reports the results of a breast carcinoma screening and diagnostic program in Harlem. METHODS:Retrospective re...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.10640
更新日期:2002-07-01 00:00:00
abstract::Chemotherapy once relegated to end stage patients has markedly improved with the use of combinations. Response rates with single agents have improved from 15 to 35%, to 50 to 70%, using combinations with an increase in complete response rates to about 25%. A series of four studies completed by the Eastern Cooperative ...
journal_title:Cancer
pub_type: 临床试验,杂志文章
doi:10.1002/1097-0142(197706)39:6<2916::aid-cncr282039
更新日期:1977-06-01 00:00:00
abstract:BACKGROUND:Non-Hodgkin lymphoma (NHL), the most common cancer of the lymphatic system, is of unknown etiology. The identification of etiologic factors in the onset of NHL is a key event that could facilitate the prevention and cure of this malignancy. Simian virus 40 (SV40) has been considered an oncogenic agent in the...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.29404
更新日期:2015-08-01 00:00:00
abstract:BACKGROUND:The current study evaluated whether the risk of developing thyroid cancer in Asian women was associated with infertility and the use of fertility drugs. METHODS:The authors conducted a large, retrospective cohort study using Taiwan's National Health Insurance Research Database. From the insurance claims dat...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.31964
更新日期:2019-05-15 00:00:00
abstract::Two human Burkitt's lymphoma cell lines (HBL-4 and HBL-5) were established individually from two patients with small noncleaved cell lymphoma (Burkitt's type). The HBL-4 cell line is Epstein-Barr virus (EBV)-negative, and the HBL-5 cell line is EBV-positive. Cytogenetically, both cell lines had the same chromosomal tr...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19920201)69:3<763::aid-cncr28206
更新日期:1992-02-01 00:00:00
abstract:BACKGROUND:The optimal imaging for the staging of oropharyngeal cancer is not well defined. METHODS:The linked Surveillance, Epidemiology, and End Results (SEER)-Medicare database for 2006 through 2011 was used to compare patient characteristics and hospital region by the initial imaging modality used for patients wit...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.32148
更新日期:2019-08-15 00:00:00
abstract:BACKGROUND:For patients who have chondrosarcoma with unresectable disease, because of tumor location, tumor size, or extensive metastatic disease, treatment options are very limited because of their relative resistance to radiotherapy and chemotherapy. The overall survival of this patient population is poor; however, s...
journal_title:Cancer
pub_type: 杂志文章,多中心研究
doi:10.1002/cncr.28845
更新日期:2014-10-15 00:00:00