Multiple visceral and cutaneous granular cell tumors. Ultrastructural and immunocytochemical evidence of Schwann cell origin.

Abstract:

:Granular cell tumor of the stomach is rare and may occur in association with similar tumors in the skin. Two such tumors were found in association with cutaneous granular cell tumors in two black females. Infiltrating carcinoma of the stomach was suspected at surgery in one case. All of the lesions were typical granular cell tumors on light microscopic examination. Ultrastructural examination showed clusters of tumor cells that were surrounded by basal laminae and axonal structures were present among the tumor cells. S-100 protein immunoreactivity was also demonstrated in the tumor cells. These findings suggest a Schwannian origin for visceral granular cell tumors.

journal_name

Cancer

journal_title

Cancer

authors

Seo IS,Azzarelli B,Warner TF,Goheen MP,Senteney GE

doi

10.1002/1097-0142(19840515)53:10<2104::aid-cncr282

subject

Has Abstract

pub_date

1984-05-15 00:00:00

pages

2104-10

issue

10

eissn

0008-543X

issn

1097-0142

journal_volume

53

pub_type

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