2b or not 2b? Shoulder function after level 2b neck dissection: A double-blind randomized controlled clinical trial.

abstract：:In certain experimental tumor models, tumor growth is less pronounced in immune deficient animals. Characteristically, tumors such as the murine B16 melanoma and Lewis lung carcinoma (3LL) are weakly antigenic. We proposed that with such tumors that are weakly antigenic, growth is enhanced by T-cell factors. Young mic...

journal_title：Cancer

authors： Ershler WB,Tuck D,Moore AL,Klopp RG,Kramer KE

更新日期：1988-05-01 00:00:00

abstract：BACKGROUND:The outcome of surgical treatment for early gastric cancer (EGC) generally is considered to be satisfactory. Although a small percentage of patients experience disease recurrence, the absolute number of such instances is too small for assessment of risk factors. METHODS:The authors investigated the follow-u...

journal_title：Cancer

authors： Sano T,Sasako M,Kinoshita T,Maruyama K

更新日期：1993-12-01 00:00:00

abstract：BACKGROUND:Prior literature has suggested synergy between immune checkpoint therapy (ICT) and radiotherapy (RT) for the treatment of brain metastases (BrM), but to the authors' knowledge the optimal timing of therapy to maximize this synergy is unclear. METHODS:A total of 199 patients with melanoma and non-small cell ...

journal_title：Cancer

authors： Qian JM,Martin AM,Martin K,Hammoudeh L,Catalano PJ,Hodi FS,Cagney DN,Haas-Kogan DA,Schoenfeld JD,Aizer AA

更新日期：2020-12-15 00:00:00

abstract：:An exceedingly rare tumor arising in the upper lateral vagina is described histologically, histochemically, and ultrastructurally. It is compared to the lesion reported by Okagaki et al. which is considered to represent the same type of tumor. Comparison with synovial sarcomas indicates that the lesion is similar, but...

journal_title：Cancer

authors： Shevchuk MM,Fenoglio CM,Lattes R,Frick HC 2nd,Richart RM

更新日期：1978-07-01 00:00:00

abstract：BACKGROUND:Topotecan is a topoisomerase I inhibitor that has good penetration across the blood-brain barrier and significant antitumor activity against human brain tumor xenografts. In a Phase I trial in children with refractory cancer, topotecan was well tolerated when administered as a 24-hour infusion. The maximum t...

journal_title：Cancer

authors： Blaney SM,Phillips PC,Packer RJ,Heideman RL,Berg SL,Adamson PC,Allen JC,Sallan SE,Jakacki RI,Lange BJ,Reaman GH,Horowitz ME,Poplack DG,Balis FM

更新日期：1996-08-01 00:00:00

abstract：BACKGROUND:Natural killer (NK) cells are a group of effector cells that act nonspecifically against tumor cells. The correlation between intratumoral NK cell infiltration and clinicopathologic features remains unclear. METHODS:The authors selected 146 patients with gastric carcinoma who underwent gastrectomy at Kagosh...

journal_title：Cancer

authors： Ishigami S,Natsugoe S,Tokuda K,Nakajo A,Che X,Iwashige H,Aridome K,Hokita S,Aikou T

更新日期：2000-02-01 00:00:00

abstract：:A series of 273 unselected patients with bronchial carcinoma, comprising a total prospective 5-year study from a Swedish county with an observed 5-year survival of 7.0%, is presented. The autopsy rate in deceased patients was 94%. All diagnoses were histologically or cytologically verified. The 5-year survival rates f...

journal_title：Cancer

authors： Nõu E

更新日期：1984-05-15 00:00:00

abstract：:Venous thromboembolism (VTE) is a frequent complication of cancer and cancer treatment and is associated with multiple clinical consequences, including recurrent VTE, bleeding, and an increase in the risk of death. Although the risks associated with VTE have been well recognized in surgical cancer patients, there is a...

journal_title：Cancer

authors： Lyman GH

更新日期：2009-12-15 00:00:00

abstract：:Thin-needle aspiration biopsy (TNAB) was performed on 22 patients with orbital tumors. Nine patients were studied before the introduction of computed tomography (CT) and only two cytologic diagnoses could be established. Thirteen aspiration biopsies guided by CT were successful. The technique of the CT-guided TNAB of ...

journal_title：Cancer

authors： Czerniak B,Woyke S,Daniel B,Krzysztolik Z,Koss LG

更新日期：1984-12-01 00:00:00

abstract：:One-hundred and fifty-one adults with acute non-lymphocytic leukemia (ANLL) were entered into an Eastern Cooperative Oncology Group protocol (EST-1473) comparing twice daily cytosine arabinoside and thioguanine (AT) with weekly cyclophosphamide, cytosine arabinoside, and methotrexate (CAM) for remission induction. Of ...

journal_title：Cancer

authors： Skeel RT,Costello W,Bennett JM,Oken MM,Tobin MS,Bertino JR,Marsh JC,Carbone PP

更新日期：1980-01-15 00:00:00

abstract：:Two children with metastatic extragonadal endodermal sinus tumor who had failed VAC chemotherapy were treated with combination chemotherapy consisting of cis-platinum, vinblastine, doxorubicin HCl (Adriamycin) and bleomycin (cis-VAB). There was a complete response in both patients with one child remaining tumor-free 3...

journal_title：Cancer

authors： Thomas WJ,Kelleher JF,Duval-Arnould B

更新日期：1981-12-01 00:00:00

abstract：BACKGROUND:To clarify the differences in angiogenesis between benign and malignant ovarian tumors, the authors examined the immunohistochemical characteristics and the density of tumor vessels in both tumor groups. Intratumoral vascularization was observed preoperatively by transvaginal color Doppler ultrasound. METHO...

journal_title：Cancer

authors： Emoto M,Iwasaki H,Mimura K,Kawarabayashi T,Kikuchi M

更新日期：1997-09-01 00:00:00

abstract：:The quantitative analysis on glycosaminoglycan (GAG) in the tumor tissues of five patients with malignant pleural mesothelioma and in the pleural fluid of two patients was performed with the use of biochemical methods. In the tumor tissues, it was found that the average of the total amount of GAG was more than 7.9 tim...

journal_title：Cancer

authors： Nakano T,Fujii J,Tamura S,Amuro Y,Nabeshima K,Horai T,Hada T,Higashino K

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND:Metallothioneins (MT) are endogenous metalloproteins involved in the homeostasis of essential metals and detoxification of toxic metals. Some recent experimental studies suggested tumor resistance to cisdiamminedichloroplatin may be associated with overexpression of MT in the tumor. METHODS:The presence of ...

journal_title：Cancer

authors： Chin JL,Banerjee D,Kadhim SA,Kontozoglou TE,Chauvin PJ,Cherian MG

更新日期：1993-11-15 00:00:00

abstract：:Tn antigen is the immediate precursor of the carcinoma (CA)-associated T antigen; both are masked in non-CA tissues. Tn antigen was detected by absorption of human anti-Tn antibody in 46 of 50 primary breast CAs and in all 6 metastases originating from Tn-positive primary CAs. Thirteen of 25 (52%) anaplastic CAs, but ...

journal_title：Cancer

authors： Springer GF,Taylor CR,Howard DR,Tegtmeyer H,Desai PR,Murthy SM,Felder B,Scanlon EF

更新日期：1985-02-01 00:00:00

abstract：:This article documents the study of 383 cases of lung cancer in uranium miners and presents for the first time the relationship of radioactive radon gas and cigarette smoking. There is evidence that alpha radiation from radon gas at exposure levels above 465 working level months (WLM) is a strong contributor to the de...

journal_title：Cancer

authors： Saccomanno G,Huth GC,Auerbach O,Kuschner M

更新日期：1988-10-01 00:00:00

abstract：BACKGROUND:The sensitivity of the intraoperative diagnosis of sentinel lymph node (SLN) micrometastases and the metastases of invasive lobular carcinoma (ILC) is low. The goal of the current study was to assess whether the use of intraoperative, rapid immunohistochistochemistry (IHC) enhances the intraoperative detecti...

journal_title：Cancer

authors： Leikola JP,Toivonen TS,Krogerus LA,von Smitten KA,Leidenius MH

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND:Clinical trials established the value of breast-conserving treatment (BCT) including the macroscopic removal of the tumor followed by local radiation therapy (RT) for Stage I and II invasive carcinomas. The occurrence of local tumor recurrence is related to the extent and multifocality of the tumor. Various ...

journal_title：Cancer

authors： Faverly DR,Hendriks JH,Holland R

更新日期：2001-02-15 00:00:00

abstract：:Previous studies and those of the authors have reported about raised levels of lipid-bound sialic acid (LSA) in sera of patients with various neoplasms. Most authors have used the method of Katopodis and Stock for isolating serum LSA. Because of the discrepancy of the amount of extracted LSA with the content of pure g...

journal_title：Cancer

authors： Voigtmann R,Pokorny J,Meinshausen A

更新日期：1989-12-01 00:00:00

abstract：:Antibodies to herpes simplex viral-induced antigens (HSVIA) were assayed by an indirect immunofluorescent technique in 93 regular cigarette smokers, 75 of whom also imbibed alcoholic beverages. Controls were 94 nonsmoking, nondrinking volunteers matched with the smoker for age and sex. IgA antibodies to HSVIA were det...

journal_title：Cancer

authors： Smith HG,Horowitz N,Silverman NA,Henson DE,Chretien PB

更新日期：1976-09-01 00:00:00

abstract：BACKGROUND:To the authors' knowledge, the empiric identification of agents and interventions to mitigate chemotherapy-induced peripheral neuropathy (CIPN) has resulted in only 1 agent that modestly mitigates it and no agents or interventions that prevent its development. This speaks to the need for a mechanistic unders...

journal_title：Cancer

authors： St Germain DC,O'Mara AM,Robinson JL,Torres AD,Minasian LM

更新日期：2020-10-15 00:00:00

abstract：BACKGROUND:Lenvatinib is an oral, multitargeted tyrosine kinase inhibitor of the vascular endothelial growth factor receptors 1 through 3 (VEGFR1-VEGFR3), fibroblast growth factor receptors 1 through 4 (FGFR1-FGFR4), platelet-derived growth factor receptor α (PDGFRα), ret proto-oncogene (RET), and v-kit Hardy-Zuckerman...

journal_title：Cancer

authors： Cabanillas ME,Schlumberger M,Jarzab B,Martins RG,Pacini F,Robinson B,McCaffrey JC,Shah MH,Bodenner DL,Topliss D,Andresen C,O'Brien JP,Ren M,Funahashi Y,Allison R,Elisei R,Newbold K,Licitra LF,Sherman SI,Ball DW

更新日期：2015-08-15 00:00:00

abstract：:To remove regionally recurrent cancer of the rectum completely, more radical extensive resections were attempted than the conventional ones in 35 patients. Twenty-two patients underwent total pelvic exenteration. In 23, sacral resection was done, combined with other procedures including excision of the entire circumfe...

journal_title：Cancer

authors： Maetani S,Nishikawa T,Iijima Y,Tobe T,Kotoura Y,Shikata J,Yamamura T

更新日期：1992-06-15 00:00:00

abstract：BACKGROUND:Management of unresectable colorectal liver metastases (CLM) can be by regional (hepatic arterial infusion [HAI]) or systemic chemotherapy, or by symptom control alone. In this study the costs of each type of management were related to clinical outcome in 134 patients with CLM. METHODS:The costs (both in te...

journal_title：Cancer

authors： Durand-Zaleski I,Earlam S,Fordy C,Davies M,Allen-Mersh TG

更新日期：1998-09-01 00:00:00

abstract：:This report describes a patient referred at 14 years in 1971, after one year's surveillance by the family physician, for a persistently elevated erythrocyte sedimentation rate, leukopenia, and relative lymphocytosis. Despite the documented myeloproliferative syndrome of seven years, significant physiologic impairment ...

journal_title：Cancer

authors： Whaun JM,Lin CC,Biederman B,Cornish SJ,Dundas JB

更新日期：1981-09-01 00:00:00

abstract：:Doxorubicin is an effective antineoplastic agent, but it frequently causes dose-related cardiotoxic effects. Because the atrial natriuretic peptide (ANP) level is elevated in children with heart defects, the authors measured the ANP levels in children to determine whether ANP might serve as a simple diagnostic indicat...

journal_title：Cancer

authors： Bauch M,Ester A,Kimura B,Victorica BE,Kedar A,Phillips MI

更新日期：1992-03-15 00:00:00

abstract：:Disparities in minorities' representation in cancer clinical trials have been shown only in adult populations, which suggest that the main causes of these disparities relate to health system-based barriers, including issues of poverty (lack of insurance), poor access to trials, and an inadequate number of clinical tri...

journal_title：Cancer

authors： Colon-Otero G,Smallridge RC,Solberg LA Jr,Keith TD,Woodward TA,Willis FB,Dunn AN

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:Despite recent advances in diagnosis and treatment, gastric carcinoma remains a major cause of death in the world. METHODS:The clinicopathologic profile of 10,000 consecutive patients who underwent primary gastrectomy during 1962-1989 were reviewed and prognostic factors influencing survival in those with g...

journal_title：Cancer

authors： Nakamura K,Ueyama T,Yao T,Xuan ZX,Ambe K,Adachi Y,Yakeishi Y,Matsukuma A,Enjoji M

更新日期：1992-09-01 00:00:00

abstract：BACKGROUND:Patients with superficial (mucosal or submucosal) esophageal carcinoma (SEC) have significantly better survival rates than patients with advanced carcinoma. Some patients with advanced esophageal carcinoma have been reported to test positive for serum p53 antibodies (Abs). Because very few patients with supe...

journal_title：Cancer

authors： Shimada H,Takeda A,Arima M,Okazumi S,Matsubara H,Nabeya Y,Funami Y,Hayashi H,Gunji Y,Suzuki T,Kobayashi S,Ochiai T

更新日期：2000-10-15 00:00:00

abstract：BACKGROUND:Gastric carcinoma with lymphoid stroma (GCLS) has been reported to have a more favorable prognosis than ordinary gastric carcinoma, however, the precise mechanism of the pathogenesis for GCLS remains unclear. METHODS:The authors analyzed 99 GCLS in 94 patients for Epstein-Barr virus (EBV) sequences using po...

journal_title：Cancer

authors： Nakamura S,Ueki T,Yao T,Ueyama T,Tsuneyoshi M

更新日期：1994-05-01 00:00:00