Abstract:
BACKGROUND:The head and neck region is one of the most common locations of rhabdomyosarcoma. Salivary gland involvement is usually secondary to advanced disease, and presentation as a primary salivary gland tumor is very rare. METHODS:Three cases of rhabdomyosarcoma presenting as parotid masses, in 2 boys (ages 3 and 7 years) and a girl (age 5 years), were retrieved from the files of 2 institutions. RESULTS:The three patients presented with parotid gland enlargement. Clinically, the enlargements appeared to be inflammatory, and they were treated unsuccessfully with antibiotics. Fine-needle aspiration biopsy (FNAB) was performed on all three patients. The cytologic features varied from one case to another; one case had features of a small round cell tumor, another was composed of a monomorphic population of spindle cells in a metachromatic stroma, and the third case was composed mostly of spindle cells with moderate cellular pleomorphism. Immunohistochemical studies performed in two of the cases confirmed the diagnosis of rhabdomyosarcoma, and ultrastructural studies were confirmatory in the other case. The patients are alive; 2 of them have had no evidence of disease after 6 and 9 years of follow-up, and the third, the most recent patient, has just finished adjuvant chemotherapy. CONCLUSIONS:With the increased use of FNAB for the evaluation of salivary gland masses in children, the authors believe that it is important to recognize the occurrence of rhabdomyosarcoma in this location. Immunohistochemical studies have proved helpful in differentiating rhabdomyosarcoma from other parotid gland tumors and can be readily done on cytologic preparations.
journal_name
Cancerjournal_title
Cancerauthors
Salomão DR,Sigman JD,Greenebaum E,Cohen MBsubject
Has Abstractpub_date
1998-08-25 00:00:00pages
245-51issue
4eissn
0008-543Xissn
1097-0142pii
10.1002/(SICI)1097-0142(19980825)84:4<245::AID-CNCjournal_volume
84pub_type
杂志文章相关文献
CANCER文献大全abstract:BACKGROUND:The purpose of this study was to evaluate the feasibility, toxicity, and efficacy of the combination of paclitaxel, carboplatin, and long-term continuous infusion 5-fluorouracil (5-FU) in the treatment of advanced squamous carcinomas of various primary sites. METHODS:Patients were eligible for this trial if...
journal_title:Cancer
pub_type: 临床试验,杂志文章
doi:10.1002/1097-0142(20010801)92:3<642::aid-cncr1365>
更新日期:2001-08-01 00:00:00
abstract:BACKGROUND:Small areas unstained with Lugol's iodine are often observed in the mucosa surrounding esophageal carcinomas. METHODS:For light microscopic evaluation, the histologic features of 131 small areas unstained by Lugol's iodine in 12 selected cases were investigated. For clinicopathologic evaluation, the numbers...
journal_title:Cancer
pub_type: 杂志文章
doi:
更新日期:1998-04-15 00:00:00
abstract:BACKGROUND:Breast reconstruction is performed with increasing frequency and has become important in the treatment of mastectomy patients. METHODS:The development of recurrent carcinoma after a mastectomy and transverse rectus abdominus myocutaneous (TRAM) flap procedure is described. RESULTS:The lesion was nonpalpabl...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19941115)74:10<2804::aid-cncr282
更新日期:1994-11-15 00:00:00
abstract:BACKGROUND:Microsatellite instability (MIN) appears to be a novel molecular mechanism in carcinogenesis and is believed to reflect multiple replication errors. The authors analyzed MIN in de novo acute leukemia and its association with expression of the human MSH3 (hMSH3) gene and point mutations of the N-ras gene. The...
journal_title:Cancer
pub_type: 杂志文章
doi:
更新日期:1998-08-01 00:00:00
abstract::Fifteen malignant schwannomas were examined by light and electron microscopy. Five tumors arose in patients with neurofibromatosis and five were contiguous with a peripheral nerve (Group I). Five tumors met neither of these generally accepted diagnostic criteria but were light microscopically seen as compatible with m...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19810915)48:6<1381::aid-cncr2820
更新日期:1981-09-15 00:00:00
abstract:BACKGROUND:Colorectal cancer incidence rates vary widely internationally, by race and gender, and have changed over time. Investigation of the patterns by subsite within the colorectum may suggest clues of possible etiologic significance for further study. METHODS:Using population-based data on more than 120,000 cases...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19930615)71:12<3819::aid-cncr282
更新日期:1993-06-15 00:00:00
abstract::Lymphoid cells from two patients with hand-mirror variant of acute lymphoblastic leukemia (ALL) were studied with various monoclonal antibodies in attempts to determine their derivation and differentiation. The predominant feature of the malignant bone marrow cells was strong reactivity with antibody 3A1, which stains...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19850101)55:1<77::aid-cncr282055
更新日期:1985-01-01 00:00:00
abstract::From January, 1973, to June, 1976, 226 patients with palpable ovarian masses were evaluated preoperatively by lymphography. Histology showed 166 cases of malignant epithelial tumors, 26 benign tumors, and 34 malignant special tumors (not included in this report). Furthermore, the group of patients included 99 recurren...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197710)40:4<1444::aid-cncr282040
更新日期:1977-10-01 00:00:00
abstract:BACKGROUND:This study was conducted to determine if pelvic computed tomography (CT) should routinely be appended to abdominal CT in the workup of patients with breast carcinoma. METHODS:The abdominal-pelvic CTs of 139 breast carcinoma patients (195 exams) were reviewed. Scans were grouped by indication and whether pel...
journal_title:Cancer
pub_type: 杂志文章
doi:
更新日期:1997-02-01 00:00:00
abstract::During 1982 and 1983, 4496 new cases were recorded in the French Registry of acute leukemia and myelodysplastic syndromes by the French Group of Hematologic Morphology. This cooperative group associated members of 37 university centers spread throughout France; these centers handle the overwhelming majority of acute l...
journal_title:Cancer
pub_type: 杂志文章
doi:
更新日期:1987-09-15 00:00:00
abstract::The serial technetium 99 (99Tc) bone scans of 76 patients with Stage D-2 prostate cancers were reviewed. Sites of metastases in skeletal areas in decreasing order were vertebrae, ribs, pelvis, long bones, and skull. Patients with one or two involved skeletal areas had a significantly longer progression-free interval a...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19910715)68:2<316::aid-cncr28206
更新日期:1991-07-15 00:00:00
abstract:BACKGROUND:Elderly people constitute a heterogeneous group and are at an increased risk for the development of cancer. It is not clear whether comorbid conditions and functional status influence clinical decisions and the pattern of referral in elderly cancer patients. The current study investigated functional status m...
journal_title:Cancer
pub_type: 杂志文章
doi:
更新日期:1998-02-15 00:00:00
abstract::Elective irradiation of sites of potential occult tumor spread is often part of a patient's radiation therapy program. The required radiation dose (D) depends on the probability that occult disease exists (P(occ)), the number of sites at risk (A), the number of tumor clonogens present (Ni), their radiation sensitivity...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19901215)66:12<2498::aid-cncr282
更新日期:1990-12-15 00:00:00
abstract::Carcinoembryonic antigen (CEA) values in 529 patients treated in two consecutive adjuvant chemotherapy protocols were analyzed to determine if CEA values correlated with disease-free status or prognostic utility. CEA values were evaluated preoperatively, before chemotherapy, at the conclusion of chemotherapy, and duri...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19890301)63:5<828::aid-cncr28206
更新日期:1989-03-01 00:00:00
abstract:BACKGROUND:According to the overview of Early Breast Cancer Trialists' Collaborative Group, anthracycline containing regimens are superior to cyclophosphamide, methotrexate, and 5-fluorouracil (CMF) as adjuvant chemotherapy for breast carcinoma, but no comparative information is available in terms of primary chemothera...
journal_title:Cancer
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1002/cncr.10678
更新日期:2002-07-15 00:00:00
abstract:BACKGROUND:NR4A2, an orphan nuclear receptor essential in the generation of dopaminergic neurons, has been recently linked to inflammation and cancer. This study sought to identify the role of NR4A2 on chemoresistance and postoperative prognosis of gastric cancer (GC). METHODS:NR4A2 was transfected into GC cells to in...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.28228
更新日期:2013-10-01 00:00:00
abstract:BACKGROUND:Recent advances in the early detection of prostatic adenocarcinoma have stimulated interest in the development of techniques for determining metastatic potential. METHODS:One hundred cases of adenocarcinoma, including 66 biopsy and radical prostatectomy specimens; 20 biopsies alone; and 14 transurethral res...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19931115)72:10<3020::aid-cncr282
更新日期:1993-11-15 00:00:00
abstract:BACKGROUND:Male breast cancer (MBC) is considered an androgen-dependent tumor, and as in prostatic cancer, responses have been reported with use of antiandrogens or gonadotropin-releasing hormone analogs. Thus, it is reasonable to postulate that better results could be achieved by combining these two agents. METHODS:E...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19930715)72:2<502::aid-cncr28207
更新日期:1993-07-15 00:00:00
abstract:BACKGROUND:Because carcinomas of unknown primary origin are highly malignant tumors with a bad prognosis (median survival, 6-12 months) and no current optimal therapy, the authors designed a prospective dose-dense chemotherapy regimen with the objective of improving the results observed in patients who receive conventi...
journal_title:Cancer
pub_type: 临床试验,杂志文章
doi:10.1002/cncr.10264
更新日期:2002-02-01 00:00:00
abstract:BACKGROUND:A rigorous assessment of the risk of colorectal cancer (CRC) among prostate cancer (PC) survivors that controls for important confounding factors and competing risks is necessary to determine the risk of CRC in this population and to inform screening guidelines. METHODS:With data from Manitoba, Canada, subj...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.29919
更新日期:2016-04-15 00:00:00
abstract:BACKGROUND:Louisiana is one of the few Southern states that enacted the Medicaid expansion of the Patient Protection and Affordable Care Act (ACA). To the authors' knowledge, the issue of how this has affected the breast cancer landscape in Louisiana is unknown. The authors have postulated that ACA expansion had a posi...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.33265
更新日期:2020-11-03 00:00:00
abstract:BACKGROUND:The purpose of the current study was to determine the prevalence of low bone mineral density (BMD) (ie, osteopenia) and identify factors associated with low BMD in young adult survivors of childhood acute lymphoblastic leukemia (ALL). METHODS:Dual energy x-ray absorptiometry was used to evaluate BMD in 74 r...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.23912
更新日期:2008-12-01 00:00:00
abstract:BACKGROUND:Heavy alcohol consumption, viral hepatitis, and diabetes are risk factors for hepatocellular carcinoma (HCC). However, to the authors' knowledge, the information concerning their interaction effect in patients with risk of HCC is sparse. METHODS:A population-based, case-control study of HCC was conducted du...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.20427
更新日期:2004-09-01 00:00:00
abstract::Thrombocytosis above 40.0 X 10(4)/mm3 occurred in five of six (83%) patients with malignant mesothelioma. In contrast, the incidence of thrombocytosis was 7.5% in patients with lung adenocarcinoma, 12.5% in squamous cell carcinoma, 5.1% in small cell carcinoma, and 41.7% in large cell carcinoma, respectively. The plat...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19861015)58:8<1699::aid-cncr2820
更新日期:1986-10-15 00:00:00
abstract:BACKGROUND:Pediatric rhabdomyosarcomas (RMS) have a more advantageous prognosis after multimodality treatment compared with adult RMS, which might be related to a decreased sensitivity to chemotherapy in adults. Resistance to chemotherapy might be conveyed by the multidrug resistance (MDR)-associated proteins P-glycopr...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.11259
更新日期:2003-04-15 00:00:00
abstract:BACKGROUND:Optimal treatments for vulvar and vaginal melanomas (VVMs) have not been identified. Herein, the authors compare molecular profiles between VVM and nongynecologic melanoma (NGM) subtypes with the objective of identifying novel, targetable biomarkers. METHODS:In total, 2304 samples of malignant melanoma that...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.30473
更新日期:2017-04-15 00:00:00
abstract:BACKGROUND:To explore the potential role of infiltrating benign B cells in classic Hodgkin disease (HD) lesions in supporting the survival of malignant Hodgkin and Reed-Sternberg (H/RS) cells, the authors initiated a pilot study of rituximab. Rituximab is used to primarily deplete normal B cells from HD lesions. METHO...
journal_title:Cancer
pub_type: 临床试验,杂志文章
doi:10.1002/cncr.11511
更新日期:2003-07-15 00:00:00
abstract::The authors estimated cancer risk among 589 patients hospitalized with Crohn's disease between 1960-1976 by calculating the ratios of observed number of cancers (O) in our hospital sample to the expected number of cancers (E) based on the age- and sex-specific cancer rates of a standard population. The authors then co...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19811215)48:12<2742::aid-cncr282
更新日期:1981-12-15 00:00:00
abstract::A 17 year old man with a primary intracranial germ cell tumor in the pituitary region is reported. Both serum alpha-fetoprotein (AFP) and serum human chorionic gonadotropin (hCG) were found elevated preoperatively. Normal levels of serum AFP and hCG were found after operation and radiotherapy. By indirect immunofluore...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197806)41:6<2315::aid-cncr282041
更新日期:1978-06-01 00:00:00
abstract::Six patients with breast cancer developed pulmonary toxicity following mitomycin therapy. The presenting symptoms were shortness of breath and a dry cough. The radiological pictures varied from a normal chest x-ray to extensive bilateral pneumonitis. The histological findings consisted of diffuse alveolar damage progr...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19800115)45:2<236::aid-cncr28204
更新日期:1980-01-15 00:00:00