Genetic polymorphisms in the human growth hormone-1 gene (GH1) and the risk of breast carcinoma.

abstract：BACKGROUND:The frequency of mutant p53 in bone marrow metastases of patients with carcinoma of the prostate (CaP) and in matched sets of metastatic and primary lesions from the same patients was investigated. The data were examined in relation to prior treatment with androgen ablation (AA) therapy and were compared wit...

journal_title：Cancer

authors： Meyers FJ,Gumerlock PH,Chi SG,Borchers H,Deitch AD,deVere White RW

更新日期：1998-12-15 00:00:00

abstract：:Two patients diagnosed as having acute promyelocytic leukemia (APL) and disseminated intravascular coagulation (DIC) were closely followed from the day of admission until completion of the first course of chemotherapy with serial coagulation studies including plasma levels of functional antithrombin III activity (AT I...

journal_title：Cancer

authors： Sandler RM,Liebman HA,Patch MJ,Teitelbaum A,Levine AM,Feinstein DI

更新日期：1983-02-15 00:00:00

abstract：:Fifteen malignant schwannomas were examined by light and electron microscopy. Five tumors arose in patients with neurofibromatosis and five were contiguous with a peripheral nerve (Group I). Five tumors met neither of these generally accepted diagnostic criteria but were light microscopically seen as compatible with m...

journal_title：Cancer

authors： Taxy JB,Battifora H,Trujillo Y,Dorfman HD

更新日期：1981-09-15 00:00:00

abstract：:A 42-year-old woman developed lower extremity weakness and sensory loss 1 year after external and intracavitary radiotherapy for Stage IB carcinoma of cervix. She has been followed for 5 years posttreatment, and the neurologic abnormalities have persisted, but no evidence of recurrent carcinoma has been found. We beli...

journal_title：Cancer

authors： Stryker JA,Sommerville K,Perez R,Velkley DE

更新日期：1990-10-01 00:00:00

abstract：BACKGROUND:With the move away from classical radical mastectomy to ever more skin-sparing procedures, there has been an ongoing discussion about how much skin and subcutaneous tissue should be resected to perform an adequate mastectomy while leaving viable skin flaps. One of the common recommendations is to dissect jus...

journal_title：Cancer

authors： Beer GM,Varga Z,Budi S,Seifert B,Meyer VE

更新日期：2002-03-15 00:00:00

abstract：BACKGROUND:The authors evaluated the role of 5-aminolevulinic acid (5-ALA)-induced fluorescence endoscopy (AFE) in the detection of flat urothelial lesions in light of the suggestions made for flat neoplastic lesions within the 1999 World Health Organization (WHO) classification of urinary bladder tumors. METHODS:From...

journal_title：Cancer

authors： Zaak D,Hungerhuber E,Schneede P,Stepp H,Frimberger D,Corvin S,Schmeller N,Kriegmair M,Hofstetter A,Knuechel R

更新日期：2002-09-15 00:00:00

abstract：BACKGROUND:This study was designed to assess the toxicity of pelvic radiation therapy, 5-fluorouracil (5-FU) administered by protracted venous infusion, and leucovorin. METHODS:Pelvic radiation therapy consisted of 50.4-54 gray (Gy) administered in 28-30 fractions. Systemic treatment consisted of leucovorin (10 mg dai...

journal_title：Cancer

authors： Martenson JA,Shanahan TG,O'Connell MJ,Cobau CD,Schroeder G,Burch PA,Levitt R,Rowland KM Jr

更新日期：1999-08-15 00:00:00

abstract：BACKGROUND:Forty patients with Stage II-III breast cancer with 10 or more positive axillary nodes were treated with mastectomy followed by four cycles of standard dose CAF (cytoxan, Adriamycin, 5-FU), followed by high dose cytoxan, cisplatin, carmustine (HDCT) with autologous bone marrow transplant support (ABMT), and ...

journal_title：Cancer

authors： Marks LB,Rosner GL,Prosnitz LR,Ross M,Vredenburgh JJ,Peters WP

更新日期：1994-12-01 00:00:00

abstract：:Cutaneous atypical fibroxanthoma (AFX) occurs in elderly persons as a small nodule or ulcernodule in actinically damaged skin of the head and neck area. The vast majority of AFX behave in a benign manner, and metastasis is rare. Eight examples of metastasizing AFX are reported. Factors that portend aggressive behavior...

journal_title：Cancer

authors： Helwig EB,May D

更新日期：1986-01-15 00:00:00

abstract：:The authors report the accuracy of mammographically guided fine-needle aspiration (FNA) for the diagnosis of nonpalpable breast lesions in a series of 71 patients. Each mammographically guided FNA was immediately followed by hookwire localization and open biopsy. Seven malignancies were identified cytologically, but t...

journal_title：Cancer

authors： Layfield LJ,Parkinson B,Wong J,Giuliano AE,Bassett LW

更新日期：1991-11-01 00:00:00

abstract：BACKGROUND:The objective of this study was to determine whether standardized treatment of germ cell tumors (GCTs) could overcome sociodemographic factors limiting patient care. METHODS:The records of all patients undergoing primary treatment for GCTs at both a public safety net hospital and an academic tertiary care c...

journal_title：Cancer

authors： Chertack N,Ghandour RA,Singla N,Freifeld Y,Hutchinson RC,Courtney K,Bowman IA,Arafat W,Meng X,Moore JA,Aydin AM,Sagalowsky AI,Margulis V,Lotan Y,Woldu SL,Bagrodia A

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:: Although platinum-based combinations are considered the best option of care for patients with advanced nonsmall cell lung cancer (NSCLC), single-agent therapy is the preferred treatment for older patients. Since the late 1990s, various combinations of third-generation agents (gemcitabine [G], vinorelbine, ...

journal_title：Cancer

authors： Russo A,Rizzo S,Fulfaro F,Adamo V,Santini D,Vincenzi B,Gebbia N,Carreca I

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:The current study was performed to create a scoring system to estimate the survival of patients with metastatic spinal cord compression (MSCC). METHODS:Based on a multivariate survival analysis of 1852 patients who were treated with radiotherapy (RT) for MSCC, a scoring system was developed. The system incl...

journal_title：Cancer

authors： Rades D,Dunst J,Schild SE

更新日期：2008-01-01 00:00:00

abstract：:Thirty-six patients were evaluated between 1965 and 1983 for glioma of the optic nerves and/or chiasm. Median follow-up was 10.2 years. Pathologic verification was obtained in 32 patients. Tumor initially confined to the optic nerve recurred in one of five patients after complete resection. The actuarial survival for ...

journal_title：Cancer

authors： Flickinger JC,Torres C,Deutsch M

更新日期：1988-02-15 00:00:00

abstract：:Lymphocyte cyclic nucleotide content was studied before and after Levamisole administration to cancer patients. Twelve patients with disseminated cancer received 100 mg/m2 on two consecutive days; nine comparable patients with disseminated cancer served as controls. Endogenous cyclic adenosine monophosphate (cAMP) and...

journal_title：Cancer

authors： Lewinski UH,Mavligit GM,Thompson WJ,Hersh EM,Ortez RA

更新日期：1979-10-01 00:00:00

abstract：BACKGROUND:Full-scale implementation of lung cancer screening in the United States will increase detection of early stages. This study was aimed at assessing the capacity required for treating those cancers. METHODS:A well-established microsimulation model was extended with treatment data from the National Cancer Data...

journal_title：Cancer

authors： Blom EF,Ten Haaf K,Arenberg DA,de Koning HJ

更新日期：2019-06-15 00:00:00

abstract：:Fourteen patients with advanced salivary gland malignancies were treated with combination chemotherapy. Five of 13 patients responded to cyclophosphamide and adriamycin and two patients in the responding groups underwent further potentially curable treatment, rendering them disease-free. Three patients with mucoepider...

journal_title：Cancer

authors： Posner MR,Ervin TJ,Weichselbaum RR,Fabian RL,Miller D

更新日期：1982-12-01 00:00:00

abstract：BACKGROUND:Ovarian surface epithelial cells are positionally organized as a single cell layer by a sheet of basement membrane. It is believed that the contact of the ovarian surface epithelial cells with the basement membrane regulates cell growth and ensures the organization of the epithelium. Disabled-2 (Dab2), a sig...

journal_title：Cancer

authors： Capo-Chichi CD,Smith ER,Yang DH,Roland IH,Vanderveer L,Cohen C,Hamilton TC,Godwin AK,Xu XX

更新日期：2002-10-15 00:00:00

abstract：BACKGROUND:Sacituzumab govitecan (IMMU-132), an antitrophoblastic cell-surface antigen (anti-Trop-2) humanized antibody-SN-38 conjugate, had encouraging efficacy in the phase 1 clinical trial. This report further examines the pharmacokinetics and safety of multiple cycles of IMMU-132 at doses of 8 or 10 mg/kg in patien...

journal_title：Cancer

authors： Ocean AJ,Starodub AN,Bardia A,Vahdat LT,Isakoff SJ,Guarino M,Messersmith WA,Picozzi VJ,Mayer IA,Wegener WA,Maliakal P,Govindan SV,Sharkey RM,Goldenberg DM

更新日期：2017-10-01 00:00:00

abstract：:To examine the relationship between smoking and stage of colorectal cancer at diagnosis, data on 2788 current smokers and 6313 nonsmokers with known stage at diagnosis were obtained from the Massachusetts Cancer Registry. The stage at diagnosis was treated as a polytomous response variable in a logit-type, log-linear ...

journal_title：Cancer

authors： Longnecker MP,Clapp RW,Sheahan K

更新日期：1989-09-15 00:00:00

abstract：:Although training programs exist in both medical oncology and geriatrics (approved by the American Board of Internal Medicine), neither is adequate to ensure an appropriate supply of physicians to assume a leadership role in the treatment of the increasing number of geriatric patients who have or will develop a malign...

journal_title：Cancer

authors： Bennett JM,Sahasrabudhe DM,Hall WJ

更新日期：1997-10-01 00:00:00

abstract：:The woman treated for gynecologic cancer must contend with a challenging group of issues in her efforts to recover psychologically in the months and years after treatment: chance of dying, changed self-perception, treatment-related menopause, impaired or lost fertility, sexual dysfunction, and relationship problems mu...

journal_title：Cancer

authors： Auchincloss SS

更新日期：1995-11-15 00:00:00

abstract：BACKGROUND:The majority of patients with astrocytomas of the cerebellum have an excellent prognosis; however, a small percentage of patients continue to do poorly. To clarify the clinical, pathologic, and treatment characteristics that determine prognosis and therapeutic recommendations, a large group of patients with ...

journal_title：Cancer

authors： Hayostek CJ,Shaw EG,Scheithauer B,O'Fallon JR,Weiland TL,Schomberg PJ,Kelly PJ,Hu TC

更新日期：1993-08-01 00:00:00

abstract：:Recent studies have indicated that the nuclear DNA content of certain malignant neoplasms can be used as an adjunct in predicting their biologic behavior. The DNA content of 99 ovarian carcinomas was determined by flow cytometric analysis of nuclei obtained from paraffin-embedded tissue. Of the 99 tumors, 51 were dipl...

journal_title：Cancer

authors： Brescia RJ,Barakat RA,Beller U,Frederickson G,Suhrland MJ,Dubin N,Demopoulos RI

更新日期：1990-01-01 00:00:00

abstract：:From November 1985 to August 1988, the National Study Group for Oesophageal Cancer collected and centralized data on 1926 new cases of oesophageal cancer in South Africa. A standard data sheet was used to record the age, sex, and condition of the patients, the site, length, and circumferential extent of the tumor, the...

journal_title：Cancer

authors： Mannell A,Murray W

更新日期：1989-12-15 00:00:00

abstract：BACKGROUND:The role of adjuvant therapy in the management of patients with malignant mixed Müllerian tumors (MMMT) of the uterus has not been defined. The outcome of planned multimodality therapy for patients with apparent early stage disease was assessed. METHODS:A pilot study was performed on 38 patients with clinic...

journal_title：Cancer

authors： Manolitsas TP,Wain GV,Williams KE,Freidlander M,Hacker NF

更新日期：2001-04-15 00:00:00

abstract：:An adequate operation for colorectal carcinoma involves removal of the primary tumor and wide excision of the mesentery with its contained regional lymph nodes and lymphovascular pathways. Enker and DeCosse state that radical resection, i.e., total mesenteric lymphadenectomy encompassing the origins of the complete ar...

journal_title：Cancer

authors： Leffall LD Jr

更新日期：1983-06-15 00:00:00

abstract：BACKGROUND:There is no consistent definition at what age patients with non-Hodgkin lymphoma (NHL) are considered "elderly." This might hamper well balanced decisions with respect to treatment. METHODS:From a population-based NHL registry the age groups younger than 60 years, 60-64 years, 65-69 years, 70-74 years, and ...

journal_title：Cancer

authors： Maartense E,Kluin-Nelemans HC,le Cessie S,Kluin PM,Snijder S,Noordijk EM

更新日期：2000-12-15 00:00:00

abstract：BACKGROUND:Lung carcinoma represents the most frequent cause of cancer death worldwide because of tumor metastases. The objective of the current study was to analyze the immunologic response during the progress of lung carcinoma metastasis. METHODS:The authors established two tumor cell lines that were derived from pr...

journal_title：Cancer

authors： So T,Takenoyama M,Ichiki Y,Mizukami M,So T,Hanagiri T,Sugio K,Yasumoto K

更新日期：2005-01-01 00:00:00

abstract：:Twelve Schwann cell tumors (two neurilemomas, six neurofibromas, and four malignant schwannomas), arising in the nasal cavity, paranasal sinuses or nasopharynx, are described. Schwann cell neoplasms only rarely develop in this area. Clinically, these tumors lead to nonspecific symptoms including nasal obstruction epis...

journal_title：Cancer

authors： Perzin KH,Panyu H,Wechter S

更新日期：1982-11-15 00:00:00