Reproducibility of the diagnosis of atypical endometrial hyperplasia: a Gynecologic Oncology Group study.

abstract：BACKGROUND:Caveolin-1 plays a regulatory role in several signaling pathways. Recently caveolin-1 was identified as a metastasis-related gene in prostate carcinoma. However, the clinical impact of caveolin-1 expression in esophageal carcinoma remains unknown. METHODS:One hundred thirty surgical specimens of esophageal ...

journal_title：Cancer

authors： Kato K,Hida Y,Miyamoto M,Hashida H,Shinohara T,Itoh T,Okushiba S,Kondo S,Katoh H

更新日期：2002-02-15 00:00:00

abstract：BACKGROUND:Hepatocyte growth factor receptor (c-met), autocrine motility factor receptor (AMFR), and urokinase-type plasminogen activator receptor (uPAR) are known to play important roles in tumor cell migration, invasion, and metastasis. The authors studied the relation between the expression patterns of these genes a...

journal_title：Cancer

authors： Taniguchi K,Yonemura Y,Nojima N,Hirono Y,Fushida S,Fujimura T,Miwa K,Endo Y,Yamamoto H,Watanabe H

更新日期：1998-06-01 00:00:00

abstract：:A retrospective study is reported of 120 consecutive cases of patients presenting with brain metastases as the primary sign of their malignancy. Primary site was found in 62 patients (53 while alive and 9 at postmortem examination) and remained unknown in 58. Lung was the most frequent primary site (45% of known sites...

journal_title：Cancer

authors： Le Chevalier T,Smith FP,Caille P,Constans JP,Rouesse JG

更新日期：1985-08-15 00:00:00

abstract：BACKGROUND:The authors analyzed the secretion of extracellular matrix-degrading proteinases, including urinary-type plasminogen activator (u-PA), matrix metalloproteinase-2 (MMP-2, gelatinase A), and MMP-9 (gelatinase B), by short term primary cultures of epithelial ovarian carcinoma cells derived from primary ovarian ...

journal_title：Cancer

authors： Fishman DA,Bafetti LM,Banionis S,Kearns AS,Chilukuri K,Stack MS

更新日期：1997-10-15 00:00:00

abstract：:The potential role of paraneoplastic Cushing's syndrome (CS) was assessed on the clinical course of patients with small cell lung cancer. A retrospective comparison was done of complications and survival rates according to the presence or absence of CS in patients with small cell lung cancer who died within 90 days of...

journal_title：Cancer

authors： Dimopoulos MA,Fernandez JF,Samaan NA,Holoye PY,Vassilopoulou-Sellin R

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:The balance among cell proliferation, cell differentiation, and cell death determines the cell number in a population as well as the size or even the stage of a tumor. Thus, to improve our understanding of the pathogenesis of neoplasms, it is important to investigate the regulation of both cell proliferation...

journal_title：Cancer

authors： Shen KL,Harn HJ,Ho LI,Yu CP,Chiu SC,Lee WH

更新日期：1998-06-15 00:00:00

abstract：:Patients with ER positive primary tumors usually have initial metastases at the more favorable sites. Twelve out of 14 patients with ER positive had first site of metastases in either bone or soft tissue. In contrast, 13 of 17 patients with negative ER developed first metastases in viscera. ER positive patients respon...

journal_title：Cancer

authors： Singhakowinta A,Saunders DE,Brooks SC,Samal B,Vaitkevicius VK

更新日期：1980-12-15 00:00:00

abstract：BACKGROUND:Because of morphologic similarities, the differential diagnosis of granulocytic sarcoma (GS) in fine-needle aspiration (FNA) specimens includes non-Hodgkin or Hodgkin lymphoma, extramedullary hematopoiesis, poorly differentiated carcinoma, and infection. METHODS:Twenty-six FNAs and 1 pleural effusion fluid ...

journal_title：Cancer

authors： Suh YK,Shin HJ

更新日期：2000-12-25 00:00:00

abstract：BACKGROUND:To the authors' knowledge, there is no standard treatment for patients with T-cell large granular lymphocyte (LGL) leukemia. Available data are limited by patient numbers and coexisting pathologies. METHODS:The authors report on the use of immunosuppressants (cyclosporin A [CSA] and low-dose oral methotrexa...

journal_title：Cancer

authors： Osuji N,Matutes E,Tjonnfjord G,Grech H,Del Giudice I,Wotherspoon A,Swansbury JG,Catovsky D

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:In addition to possessing many physiologic functions, human growth hormone-1 (GH1) has been shown in recent in vitro and in vivo experiments to induce malignant disease, including breast carcinoma. The authors investigated the association of breast carcinoma with genetic polymorphisms in the GH1 gene in the ...

journal_title：Cancer

authors： Ren Z,Cai Q,Shu XO,Cai H,Cheng JR,Wen WQ,Gao YT,Zheng W

更新日期：2004-07-15 00:00:00

abstract：:The therapeutic effect of prednimustine was studied in 35 patients with advanced breast cancer resistant to previous cytotoxic and/or endocrine therapy. Response (PR + CR) was obtained in 14 patients (40%) of a median duration of five months. Among the 14 responding patients, 10 were resistant to previous endocrine th...

journal_title：Cancer

authors： Mouridsen HT,Kristensen D,Nielsen JH,Dombernowsky P

更新日期：1980-07-15 00:00:00

abstract：BACKGROUND:Data suggest that vitamin D plays a role in the treatment and prevention of prostate cancer. The combination of high-dose, intermittent calcitriol (1,25 dihydroxyvitamin D3) plus dexamethasone was studied based on evidence that dexamethasone potentiates the antitumor effects of calcitriol and ameliorates hyp...

journal_title：Cancer

authors： Trump DL,Potter DM,Muindi J,Brufsky A,Johnson CS

更新日期：2006-05-15 00:00:00

abstract：BACKGROUND:Current cervical cancer screening approaches are based on cytology supplemented by human papillomavirus (HPV) testing in some settings. Whereas cytology is laborious and depends on the cytologists' experience, HPV testing has limited specificity when it is used to detect high-grade lesions. A dichotomous tes...

journal_title：Cancer

authors： Wentzensen N,Hampl M,Herkert M,Reichert A,Trunk MJ,Poremba C,Ridder R,von Knebel Doeberitz M

更新日期：2006-11-01 00:00:00

abstract：:In a retrospective review (1950-1975) of the Mayo Clinic experience with seminomas (483 cases), twelve patients (2.5%) were found to have a retroperitoneal seminoma without evidence of testicular involvement. The mean age was 47 years (range, 31-67). Eleven patients were treated by radiation alone, with doses ranging ...

journal_title：Cancer

authors： Buskirk SJ,Evans RG,Farrow GM,Earle JD

更新日期：1982-05-01 00:00:00

abstract：:During the period 1955 to 1975, 63 consecutive cases of apical lung carcinoma were treated in the Radiation Therapy Division of the University of Michigan Medical Center (UMMC). Supervoltage external radiation alone or combination of radiation and surgery were the main modalities of treatment used in these patients. O...

journal_title：Cancer

authors： Ahmad K,Fayos JV,Kirsh MM

更新日期：1984-09-01 00:00:00

abstract：:Breast cancer is serious public health problem in countries of all resource levels. Although major advances in the detection and treatment of the disease have occurred in higher income settings, similar progress has been slow or scarce in most low- and middle-income countries (LMCs). The poorer outcomes in LMCs may re...

journal_title：Cancer

authors： Harford J,Azavedo E,Fischietto M,Breast Health Global Initiative Healthcare Systems Panel.

更新日期：2008-10-15 00:00:00

abstract：BACKGROUND:Synovial sarcoma usually arises in the extremities and in close proximity to large joints. Reported examples arising in the anterior abdominal wall are rare. Because most accounts from this location consist of case reports, neither clinical nor prognostic features have been well delineated. METHODS:Twenty-s...

journal_title：Cancer

authors： Fetsch JF,Meis JM

更新日期：1993-07-15 00:00:00

abstract：BACKGROUND:Because studies have suggested that anemia has an adverse effect on outcome for patients with cervical carcinoma who are treated with radiation, recombinant human erythropoietin (rHuEpo) has been used increasingly to maintain hemoglobin levels in these patients. Erythropoietin may increase the risk of thromb...

journal_title：Cancer

authors： Wun T,Law L,Harvey D,Sieracki B,Scudder SA,Ryu JK

更新日期：2003-10-01 00:00:00

abstract：:A case of a patient with a metastatic ACTH (adrenocorticotrophic hormone)-producing gastric carcinoid APUD (amine precursor uptake and decarboxylation) tumor is presented. The patient presented with Cushing's syndrome and very high levels of ACTH. The Cushing's syndrome was controlled medically, and when the patient d...

journal_title：Cancer

authors： Marcus FS,Friedman MA,Callen PW,Churg A,Harbour J

更新日期：1980-09-01 00:00:00

abstract：:Twenty-four women with ovarian carcinoma that had metastasized to the liver were treated with intrahepatic infusional therapy. No consistent drug regimen was used. There were no complete responders; however, 33% had a partial response. All responses were noticed after the first course of therapy. The median length of ...

journal_title：Cancer

authors： Malone JM Jr,Gershenson DM,Carrasco CH,Charansangavej C,Copeland LJ,Larson DM,Kavanagh JJ,Edwards CL,Wallace S

更新日期：1987-06-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to determine risk factors that affect locoregional control of nasopharyngeal carcinoma (NPC) after radiotherapy. Computed tomography (CT) is utilized for radiotherapy planning and for identifying high risk anatomic areas. METHODS:Between April 1990 and December 1993, 40 consecu...

journal_title：Cancer

authors： Jian JJ,Cheng SH,Prosnitz LR,Tsai SY,Tsai MJ,Huang AT

更新日期：1998-01-15 00:00:00

abstract：BACKGROUND:African-American (AA) women have lower survival rates from cervical cancer compared with white women. The objective of this study was to examine the influence of socioeconomic status (SES) and other variables on racial disparities in overall survival among women with invasive cervical cancer. METHODS:One th...

journal_title：Cancer

authors： Movva S,Noone AM,Banerjee M,Patel DA,Schwartz K,Yee CL,Simon MS

更新日期：2008-03-15 00:00:00

abstract：BACKGROUND:Failure to detect metastasis to para-aortic nodes in patients with locally advanced cervical cancer leads to suboptimal treatment. No previous studies have prospectively compared positron emission tomography (PET)/computed tomography (CT) with laparoscopic extraperitoneal staging in the evaluation of para-ao...

journal_title：Cancer

authors： Ramirez PT,Jhingran A,Macapinlac HA,Euscher ED,Munsell MF,Coleman RL,Soliman PT,Schmeler KM,Frumovitz M,Ramondetta LM

更新日期：2011-05-01 00:00:00

abstract：:Twelve patients who presented with extranodal small lymphocytic proliferations were studied. The patients ranged in age from 33 to 67 years; six were male and six female. Locations of the initial lesion included the conjunctiva and orbit, lung, stomach, small bowel, skin, and subcutis. The histopathologic picture in a...

journal_title：Cancer

authors： Evans HL

更新日期：1982-01-01 00:00:00

abstract：LAY SUMMARY:Cancer has substantial economic impacts for patients, their families and/or caregivers, employers, and the health care system. However, there is only limited understanding of how economic issues can affect access to cancer care services and the receipt of high-quality cancer care. Health economics research ...

journal_title：Cancer

authors： Halpern MT,Shih YT,Yabroff KR,Ekwueme DU,Bradley CJ,Davidoff AJ,Sabik LM,Lipscomb J

更新日期：2020-11-25 00:00:00

abstract：BACKGROUND:The sensitivity of the intraoperative diagnosis of sentinel lymph node (SLN) micrometastases and the metastases of invasive lobular carcinoma (ILC) is low. The goal of the current study was to assess whether the use of intraoperative, rapid immunohistochistochemistry (IHC) enhances the intraoperative detecti...

journal_title：Cancer

authors： Leikola JP,Toivonen TS,Krogerus LA,von Smitten KA,Leidenius MH

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND:The ability of screening mammography programs serving women of different socioeconomic status (SES) to diagnose early stage breast carcinoma in a comparably effective fashion has been questioned. METHODS:Results of screening 50,653 women of lower SES were compared with those of screening 45,923 more socioec...

journal_title：Cancer

authors： Dershaw DD,Loring L,True SJ,Momrow DC,Liberman L,Morris EA

更新日期：1998-05-01 00:00:00

abstract：BACKGROUND:Although state Medicaid programs cover cancer screening, Medicaid beneficiaries are less likely to be screened for cancer and are more likely to present with tumors of an advanced stage than are those with other insurance. The current study was performed to determine whether state Medicaid eligibility and re...

journal_title：Cancer

authors： Halpern MT,Romaire MA,Haber SG,Tangka FK,Sabatino SA,Howard DH

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:The current study was conducted to evaluate the maximum tolerable dose of weekly gemcitabine administered simultaneously with radiation and cisplatin in patients with locally advanced nonsmall cell lung cancer (NSCLC). METHODS:Patients with stage IIIA/B NSCLC received concurrently 63 grays radiation and 20 ...

journal_title：Cancer

authors： Momm F,Kaden M,Tannock I,Schumacher M,Hasse J,Henke M

更新日期：2010-10-15 00:00:00

abstract：BACKGROUND:Previous Commission on Cancer studies have examined time trends in stage of disease, treatment patterns, and survival for special populations. Reported herein are the most current National Cancer Data Base data for Hispanics. METHODS:Two Calls for Data have yielded a total of 23,650 cancer reports for Hispa...

journal_title：Cancer

authors： Villar HV,Menck HR

更新日期：1994-10-15 00:00:00