Impact of preexisting tumor necrosis on the efficacy of stereotactic radiosurgery in the treatment of brain metastases in women with breast cancer.

abstract：BACKGROUND:Recently, the authors identified molecular signatures and pathways associated with nonsmall cell lung carcinoma histology and lung development. They hypothesized that genetic classifiers of histology would provide insight into lung tumorigenesis and would be associated with clinical outcome when evaluated in...

journal_title：Cancer

authors： Shah L,Walter KL,Borczuk AC,Kawut SM,Sonett JR,Gorenstein LA,Ginsburg ME,Steinglass KM,Powell CA

更新日期：2004-10-01 00:00:00

abstract：:A case of thymoma in a 12-year-old boy is presented. The patient had a history of thymic irradiation in infancy, and a family history of leukemia. The mass was readily resected and the patient is well 10 years later. The tumor contained an unusual admixture of normal thymic tissue with the neoplastic epithelial elemen...

journal_title：Cancer

authors： Chatten J,Katz SM

更新日期：1976-02-01 00:00:00

abstract：BACKGROUND:The first step of colorectal carcinoma spread depends on the ability of the tumor cells to degrade and invade the extracellular matrix (ECM). The objectives of the current study were to evaluate the serum pattern of laminin, C-terminal peptide of Type I (PIP), and N-terminal peptide of Type III (PIIIP) proco...

journal_title：Cancer

authors： Plebani M,Basso D,Roveroni G,De Paoli M,Galeotti F,Corsini A

更新日期：1997-04-01 00:00:00

abstract：:In this study of 2092 women with cancer of the breast, those who had practiced breast self-examination (BSE) had earlier cancer than did those who had not practiced BSE. This was true for both black and white races, all educational and economic levels, each age group, and within each period of delay between first symp...

journal_title：Cancer

authors： Huguley CM Jr,Brown RL

更新日期：1981-03-01 00:00:00

abstract：BACKGROUND:New biologic prognostic factors are needed to guide the treatment of patients with colorectal cancer. The prognostic value of the altered expression of the cell surface glycoprotein gp78, which has been implicated in tumor-cell invasion and metastasis as an autocrine motility factor (AMF) receptor, was evalu...

journal_title：Cancer

authors： Nakamori S,Watanabe H,Kameyama M,Imaoka S,Furukawa H,Ishikawa O,Sasaki Y,Kabuto T,Raz A

更新日期：1994-10-01 00:00:00

abstract：BACKGROUND:Bortezomib is active in heavily pretreated multiple myeloma patients; the dose-limiting toxicity is peripheral neuropathy (PN). METHODS:The authors retrospectively reviewed the incidence, severity, and risk factors for PN in 78 patients who received bortezomib. The median age was 57 years (range, 33-80 year...

journal_title：Cancer

authors： Badros A,Goloubeva O,Dalal JS,Can I,Thompson J,Rapoport AP,Heyman M,Akpek G,Fenton RG

更新日期：2007-09-01 00:00:00

abstract：:A case of endometrial adenoacanthoma is reported in which two histologically distinct populations of cells were identified in the primary tumor. The two cell types differed in that one had phagocytosed large numbers of polymorphonuclear leucocytes. A subsequent skin metastasis was composed entirely of cells capable of...

journal_title：Cancer

authors： Chandrasoma P

更新日期：1980-05-01 00:00:00

abstract：:The molecular genetic alterations in colorectal carcinoma are among the best understood of any common human cancer. Identified abnormalities include both dominant-acting oncogenes (ras, myc, src) and suppressor genes which undergo inactivation or deletion (deleted in colorectal carcinoma gene [DCC], p53, adenomatous p...

journal_title：Cancer

authors： Hamilton SR

更新日期：1992-03-15 00:00:00

abstract：:From February 1972 to July 1975, 200 lung cancer patients were seen at the University of Rochester Cancer Center's Division of Radiation Oncology; 40% had squamous cell tumors and 87.5% had advanced disease localized to the thorax. Of the 160 patients who completed treatment, 101 were treated with continuous therapy s...

journal_title：Cancer

authors： Salazar OM,Rubin P,Brown JC,Feldstein ML,Keller BE

更新日期：1976-06-01 00:00:00

abstract：BACKGROUND:The identification of high risk patients with endometrial carcinoma is considered essential for individualized therapy to improve prognosis and avoid overtreatment. The goal of the current study was to investigate the prognostic value of nuclear morphometry, particularly for patients with localized endometri...

journal_title：Cancer

authors： Salvesen HB,Iversen OE,Akslen LA

更新日期：1998-09-01 00:00:00

abstract：:Arylsulfatase B activity has been determined in 24-hour urine samples from 243 patients with colorectal cancer. Elevated activity of the enzyme was obsereved in 172 out of 243 (71%) patients. Employing Dukes' modified classification of colorectal cancer, urine arylsulfatase B activity was elevated in Dukes' A lesions-...

journal_title：Cancer

authors： Morgan LR Jr,Samuels MS,Thomas W,Krementz ET,Meeker W

更新日期：1975-12-01 00:00:00

abstract：BACKGROUND:While the question of whether the trials of breast cancer screening have resulted in a reduction in breast cancer death has been the subject of much scrutiny, there has been less attention to the reduction in tumor size achieved by screening. METHODS:Size data for invasive breast tumors were assembled from ...

journal_title：Cancer

authors： Michaelson JS,Satija S,Kopans D,Moore R,Silverstein M,Comegno A,Hughes K,Taghian A,Powell S,Smith B

更新日期：2003-11-15 00:00:00

abstract：:Cutaneous atypical fibroxanthoma (AFX) occurs in elderly persons as a small nodule or ulcernodule in actinically damaged skin of the head and neck area. The vast majority of AFX behave in a benign manner, and metastasis is rare. Eight examples of metastasizing AFX are reported. Factors that portend aggressive behavior...

journal_title：Cancer

authors： Helwig EB,May D

更新日期：1986-01-15 00:00:00

abstract：BACKGROUND:Several large studies have reported an extremely low incidence of MET gene amplification (GA) in patients with radically resected gastric cancer. This study was conducted to evaluate the prevalence and prognostic role of MET in patients with recurrent=metastatic gastric cancer who received chemotherapy. MET...

journal_title：Cancer

authors： An X,Wang F,Shao Q,Wang FH,Wang ZQ,Wang ZQ,Chen C,Li C,Luo HY,Zhang DS,Xu RH,Li YH

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Gene expression profiling should be applicable to needle biopsy samples if microarray technology is to become practically useful for clinical research or management of breast carcinoma. This study compared gene expression profiles derived from fine-needle aspiration biopsy (FNAB) and from core needle biopsy ...

journal_title：Cancer

authors： Symmans WF,Ayers M,Clark EA,Stec J,Hess KR,Sneige N,Buchholz TA,Krishnamurthy S,Ibrahim NK,Buzdar AU,Theriault RL,Rosales MF,Thomas ES,Gwyn KM,Green MC,Syed AR,Hortobagyi GN,Pusztai L

更新日期：2003-06-15 00:00:00

abstract：BACKGROUND:The carboplatin-based chemotherapeutic regimen M-CAVI (methotrexate, carboplatin, and vinblastine) is active against bladder carcinoma and can be administered to patients who are ineligible to receive cisplatin or doxorubicin. The authors designed a randomized study to evaluate whether M-CAVI offers a therap...

journal_title：Cancer

authors： Bellmunt J,Ribas A,Eres N,Albanell J,Almanza C,Bermejo B,Solé LA,Baselga J

更新日期：1997-11-15 00:00:00

abstract：:Carcinoembryonic antigen (CEA) was measured in 147 patients at diagnosis of small cell lung cancer; 17% of patients with limited disease and 51% with extensive disease had an abnormal CEA level (greater than 10 ng/ml). The median level was higher in extensive than in limited disease (11 ng/ml and 5.8 ng/ml, respective...

journal_title：Cancer

authors： Laberge F,Fritsche HA,Umsawasdi T,Carr DT,Welch S,Murphy WK,Chiuten DF,Dhingra HM,Farha P,Spitzer G

更新日期：1987-06-15 00:00:00

abstract：:Vitamin B6 is involved in many biological processes of potential relevance to carcinogenesis and tumor growth, including DNA synthesis and maintenance of immunocompetence, yet very little information exists on B6 nutritional status in childhood leukemia. Using a radioenzymatic assay, the authors measured plasma pyrido...

journal_title：Cancer

authors： Pais RC,Vanous E,Hollins B,Faraj BA,Davis R,Camp VM,Ragab AH

更新日期：1990-12-01 00:00:00

abstract：:In a retrospective analysis of 166 patients with chronic hepatitis B followed for up to 8 years, 22 patients had 29 episodes of elevations in serum alpha-fetoprotein (AFP) levels. Twenty-five episodes were due to a transient exacerbation of the underlying hepatitis and 11 of these episodes were followed by a loss of h...

journal_title：Cancer

authors： Di Bisceglie AM,Hoofnagle JH

更新日期：1989-11-15 00:00:00

abstract：:The initial response and long-term follow-up of 74 evaluable patients who received combination chemotherapy for metastatic nonseminomatous testicular cancer are reported. Patients were treated with a protocol (VAB-3) including vinblastine, actinomycin-D, bleomycin, and cis-dichlorodiammine platinum (DDP). VAB-3 alone ...

journal_title：Cancer

authors： Reynolds TF,Vugrin D,Cvitkovic E,Cheng E,Braun DW Jr,O'Hehir MA,Dukeman ME,Whitmore WF Jr,Golbey RB

更新日期：1981-08-15 00:00:00

abstract：:Plasminogen activator is a serine protease which exists in two forms, known as tissue-type plasminogen activator and urokinase-type plasminogen activator. Here, we show that urokinase-type plasminogen activator activity in primary breast carcinomas correlates with both size of tumor and number of axillary nodes with m...

journal_title：Cancer

authors： Duffy MJ,O'Grady P,Devaney D,O'Siorain L,Fennelly JJ,Lijnen HJ

更新日期：1988-08-01 00:00:00

abstract：:This paper describes an unusual, familial bilateral papillary cystadenoma of the epididymis found in three siblings. The histological characteristics of the tumor were: 1) papillary proliferation of clear cells, consisting of both tall columnar and round ovoid cells, in the efferent duct epithelium; and 2) cystic dila...

journal_title：Cancer

authors： Tsuda H,Fukushima S,Takahashi M,Hikosaka Y,Hayashi K

更新日期：1976-04-01 00:00:00

abstract：BACKGROUND:Black females have lower breast carcinoma survival rates compared with white females. One possible reason is that black females have more advanced-stage breast disease. Another factor may be racial differences in the utilization of cancer treatments. METHODS:The authors determined racial differences in 6-ye...

journal_title：Cancer

authors： Chu KC,Lamar CA,Freeman HP

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND:NR4A2, an orphan nuclear receptor essential in the generation of dopaminergic neurons, has been recently linked to inflammation and cancer. This study sought to identify the role of NR4A2 on chemoresistance and postoperative prognosis of gastric cancer (GC). METHODS:NR4A2 was transfected into GC cells to in...

journal_title：Cancer

authors： Han Y,Cai H,Ma L,Ding Y,Tan X,Chang W,Guan W,Liu Y,Shen Q,Yu Y,Zhang H,Cao G

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Interferon-alpha (IFN-alpha) has shown significant activity in the treatment of BCR-ABL-negative myeloproliferative disorders (MPDs), particularly essential thrombocythemia (ET) and polycythemia vera (PV). PEG-IFN-alpha-2b is a pegylated IFN-alpha-2b with a significant advantage over nonpegylated form in tha...

journal_title：Cancer

authors： Jabbour E,Kantarjian H,Cortes J,Thomas D,Garcia-Manero G,Ferrajoli A,Faderl S,Richie MA,Beran M,Giles F,Verstovsek S

更新日期：2007-11-01 00:00:00

abstract：LAY SUMMARY:Cancer has substantial economic impacts for patients, their families and/or caregivers, employers, and the health care system. However, there is only limited understanding of how economic issues can affect access to cancer care services and the receipt of high-quality cancer care. Health economics research ...

journal_title：Cancer

authors： Halpern MT,Shih YT,Yabroff KR,Ekwueme DU,Bradley CJ,Davidoff AJ,Sabik LM,Lipscomb J

更新日期：2020-11-25 00:00:00

abstract：BACKGROUND:In regional lymph node metastasis of cutaneous melanoma, the number and volume of involved lymph nodes are the most important prognostic factors. Several studies have revealed that palpation of the lymphatic drainage area(s) and regional lymph nodes has a high rate of false-negative results during follow-up....

journal_title：Cancer

authors： Blum A,Schlagenhauff B,Stroebel W,Breuninger H,Rassner G,Garbe C

更新日期：2000-06-01 00:00:00

abstract：BACKGROUND:The authors evaluated the effects of taxol, a microtubular inhibitor, as a possible radiation sensitizer on the human leukemic cell line (HL-60). Taxol acts as a mitotic inhibitor, blocking cells in the G2M-phase of the cell cycle. The differential radiation sensitivity of cells in various phases of the cell...

journal_title：Cancer

authors： Choy H,Rodriguez FF,Koester S,Hilsenbeck S,Von Hoff DD

更新日期：1993-06-01 00:00:00

abstract：BACKGROUND:Although randomized controlled trials (RCTs) require a great deal of time, money, and effort, the majority of them have resulted in failure to verify a priori hypotheses. Therefore, the intention in the current study was to clarify the differential elements of studies with 'positive' and 'negative' outcomes....

journal_title：Cancer

authors： Yanada M,Narimatsu H,Suzuki T,Matsuo K,Naoe T

更新日期：2007-07-15 00:00:00

abstract：METHODS:Three-hundred seventy patients with borderline tumors treated between 1970 and 1982 at the Norwegian Radium Hospital were analyzed retrospectively for clinicopathologic features, treatment, and survival characteristics. RESULTS:One hundred seventy-eight patients had mucinous tumors, 174 patients had serous tum...

journal_title：Cancer

authors： Kaern J,Tropé CG,Abeler VM

更新日期：1993-03-01 00:00:00