Impact of preexisting tumor necrosis on the efficacy of stereotactic radiosurgery in the treatment of brain metastases in women with breast cancer.

abstract：:We report on an 89-year-old female admitted with signs of intestinal obstruction in whom three independent adenocarcinomas of the proximal jejunum were found. Multiple foci of pyloric gland metaplasia, glandular hyperplasia and dysplasia, carcinoma-in-situ, and several varieties of adenocarcinoma were identified on mi...

journal_title：Cancer

authors： Warner TF,Peralta J

更新日期：1979-09-01 00:00:00

abstract：BACKGROUND:Vascular endothelial growth factor-C (VEGF-C) plays an important role in lymphangiogenesis and activates VEGF receptor-3 (VEGFR-3). Lymphatic spread is an important prognostic factor in patients with lung adenocarcinoma. The aim of the current study was to determine whether the expression of VEGF-C and VEGFR...

journal_title：Cancer

authors： Kojima H,Shijubo N,Yamada G,Ichimiya S,Abe S,Satoh M,Sato N

更新日期：2005-10-15 00:00:00

abstract：:In recent years a major focus in the delivery of cancer prevention services has been on the actions of physicians in ambulatory care practice. Whereas delivery of these services has increased markedly, it is likely that physician actions overall are not producing expected measurable benefits to whole populations. The ...

journal_title：Cancer

authors： Love RR

更新日期：1994-08-15 00:00:00

abstract：:Records of 100 consecutive hospitalized cancer patients referred for psychiatric consultation were reviewed. These patients constituted only 5% of those seen by the Psychiatry Consultation Service during the study period. Fifty-six percent of the referred patients were diagnosed as depressed and 40% as having organic ...

journal_title：Cancer

authors： Levine PM,Silberfarb PM,Lipowski ZJ

更新日期：1978-09-01 00:00:00

abstract：BACKGROUND:Because of the structural and biochemical similarities between the antitumor p53 and p73 proteins, the authors hypothesized that individuals who carry high-risk genotypes of p53 codon 72 and p73 G4C14-to-A4T14 polymorphisms have a higher risk of developing second primary malignancy (SPM) after index squamous...

journal_title：Cancer

authors： Zhang Y,Sturgis EM,Huang Z,Zafereo ME,Wei Q,Li G

更新日期：2012-01-15 00:00:00

abstract：BACKGROUND:Patients with hereditary leiomyomatosis and renal cell carcinoma (HLRCC) resulting from fumarate hydratase (FH) mutations may present with skin, uterine, and renal tumors, with each having unique pathologic features. This study investigated the association between prospectively identified suspicious patholog...

journal_title：Cancer

authors： Kopp RP,Stratton KL,Glogowski E,Schrader KA,Rau-Murthy R,Russo P,Coleman JA,Offit K

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:In spite of many reports, it remains unclear whether the presence of tumor cells in circulating blood flow predicts a poor prognosis. METHODS:Competitive seminested reverse transcriptase-polymerase chain reaction (RT-PCR), a technique for the quantitative detection of tumor cells, was applied to detect the ...

journal_title：Cancer

authors： Sadahiro S,Suzuki T,Tokunaga N,Yurimoto S,Yasuda S,Tajima T,Makuuchi H,Murayama C,Matsuda K

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND:Current clinical guidelines recommend earlier, more intensive breast cancer screening with both magnetic resonance imaging (MRI) and mammography for women with breast cancer susceptibility gene (BRCA) mutations. Unspecified details of screening schedules are a challenge for implementing guidelines. METHODS:...

journal_title：Cancer

authors： Cott Chubiz JE,Lee JM,Gilmore ME,Kong CY,Lowry KP,Halpern EF,McMahon PM,Ryan PD,Gazelle GS

更新日期：2013-03-15 00:00:00

abstract：BACKGROUND:Germ cell tumors (GCTs) in adolescent and young males are very sensitive to cisplatin-based chemotherapy. However, 10-20% of the patients cannot be cured by currently available therapeutic options. Once a tumor does not respond to cisplatin, current therapeutic modalities offer only a chance for short pallia...

journal_title：Cancer

authors： Kollmannsberger C,Mayer F,Pressler H,Koch S,Kanz L,Oosterhuis JW,Looijenga LH,Bokemeyer C

更新日期：2002-07-15 00:00:00

abstract：:Because increased effects have been achieved when murine tumors are irradiated after a period of hypoxia and because of anecdotal clinical experiences of an improved result after irradiation of previously anemic patients in hyperbaric oxygen, the relationship between irradiation and increased survival was investigated...

journal_title：Cancer

authors： Sealy R,Jacobs P,Wood L,Levin W,Barry L,Boniaszczuk J,Blekkenhorst G

更新日期：1989-08-01 00:00:00

abstract：:Chemotherapy of advanced stages of large bowel cancer has until recently made little progress since the introduction of 5-FU 16 years ago. While survival is improved for patients who respond, 5-FU alone has made little impact on life span of the overall population of patients. Mitomycin-C and the chloroethyl nitrosour...

journal_title：Cancer

authors： Schein PS,Kisner D,MacDonald JS

更新日期：1975-12-01 00:00:00

abstract：:A comprehensive immunologic and serologic analysis was performed on 31 untreated patients with Hodgkin's disease. Immune evaluations stressed T-cell functional activity and included traditional parameters (PHA responsiveness and delayed hypersensitivity skin reactivity), as well as newer functional assays (T-cell colo...

journal_title：Cancer

authors： Schulof RS,Bockman RS,Garofalo JA,Cirrincione C,Cunningham-Rundles S,Fernandes G,Day NK,Pinsky CM,Incefy GS,Thaler HT,Good RA,Gupta S

更新日期：1981-08-15 00:00:00

abstract：:The International Breast Cancer Study Group (formerly the Ludwig Group) has conducted nine clinical trials since 1978 (see the Appendix for participants and authors). Biologic hypotheses related to the combined use of chemotherapy and endocrine therapy in women with operable breast cancer were tested. Questions of tim...

journal_title：Cancer

authors： Goldhirsch A,Gelber RD,Castiglione M,Price KN,Rudenstam CM,Lindtner J,Collins J,Senn HJ,Brunner KW,Galligioni E

更新日期：1994-08-01 00:00:00

abstract：BACKGROUND:The long-term impact of breast carcinoma and its treatment was assessed in 153 breast carcinoma survivors previously treated on a Phase III randomized trial (Cancer and Leukemia Group B [CALGB 7581]) a median of 20 years after entry to CALGB 7581. METHODS:Survivors were interviewed by telephone using the fo...

journal_title：Cancer

authors： Kornblith AB,Herndon JE 2nd,Weiss RB,Zhang C,Zuckerman EL,Rosenberg S,Mertz M,Payne D,Jane Massie M,Holland JF,Wingate P,Norton L,Holland JC

更新日期：2003-08-15 00:00:00

abstract：BACKGROUND:Squamous cell lung carcinoma (SLC), the most frequent type of lung cancer, generally is treated surgically and its prognosis is poor. The only current clinically useful prognostic criterion is lymph node staging (TNM classification). Expression of a novel tumor-associated carbohydrate epitope Gal beta 1-3[Fu...

journal_title：Cancer

authors： Battifora H,Sorensen HR,Mehta P,Ahn C,Niland J,Hage E,Pettijohn DE,Olsson L

更新日期：1992-10-01 00:00:00

abstract：:Parathyroid adenomas are subdivided into chief cell and oxyphil cell variants. However, the parathyroid carcinomas described thus far have been only of the chief cell type. Two cases of oxyphil cell carcinoma of the parathyroid gland are reported, with light and electron microscopic study. The patients presented appar...

journal_title：Cancer

authors： Obara T,Fujimoto Y,Yamaguchi K,Takanashi R,Kino I,Sasaki Y

更新日期：1985-04-01 00:00:00

abstract：BACKGROUND:The purpose of the current analysis was to evaluate the impact of local recurrence (LR) on the development of distant metastases (DM), overall survival (OS), and cause specific survival (CSS) in patients with early-stage breast carcinoma who underwent conservative surgery (CS) and received postoperative radi...

journal_title：Cancer

authors： Vicini FA,Kestin L,Huang R,Martinez A

更新日期：2003-02-15 00:00:00

abstract：:Flow cytometry studies of the DNA distribution of tumor cells from 92 human breast cancers showed measurable aneuploidy (hyperploidy) in 83 cases (92%). The DNA ploidy values were unimodal in each case, but there was a bimodal distribution for the entire series. One group of tumors had a diploid or near diploid DNA di...

journal_title：Cancer

authors： Olszewski W,Darzynkiewicz Z,Rosen PP,Schwartz MK,Melamed MR

更新日期：1981-08-15 00:00:00

abstract：BACKGROUND:Secondary acute myeloid leukemia (AML) after treatment with epipodophyllotoxins is being observed with increased frequency. Therapeutic options are limited for patients with secondary AML and the role of bone marrow transplantation is unclear. METHODS:The authors report the treatment outcome of a cohort of ...

journal_title：Cancer

authors： Sandler ES,Friedman DJ,Mustafa MM,Winick NJ,Bowman WP,Buchanan GR

更新日期：1997-03-01 00:00:00

abstract：:Forty-one previously untreated patients with a diagnosis of acute myelogenous leukemia (AML) were entered on a study using early intensification followed by a short-term maintenance chemotherapy. Induction and early intensification consisted of three to four cycles of doxorubicin, vincristine, cytosine arabinoside (Ar...

journal_title：Cancer

authors： Kantarjian HM,Keating MJ,Walters RS,McCredie KB,Bodey GP,Freireich EJ

更新日期：1986-10-15 00:00:00

abstract：BACKGROUND:This study was conducted to evaluate whether estramustine (estrogen mustard [EM]) is a promising alternative in the treatment of patients with epithelial ovarian carcinoma (OVCA). EM is a microtubule-associated protein (MAP) specific antimicrotubule agent with low toxicity. METHODS:The authors investigated ...

journal_title：Cancer

authors： Chen Z,Fadiel A,Jia JF,Sakamoto H,Carbone R,Naftolin F

更新日期：1999-06-15 00:00:00

abstract：BACKGROUND:Cancer clinicians do not receive routine training in the psychosocial aspects of patient care such as how to communicate bad news or respond to patients who have unrealistic expectations of cure. Postgraduate workshops may be an effective way to increase interpersonal skills in managing these stressful patie...

journal_title：Cancer

authors： Baile WF,Kudelka AP,Beale EA,Glober GA,Myers EG,Greisinger AJ,Bast RC Jr,Goldstein MG,Novack D,Lenzi R

更新日期：1999-09-01 00:00:00

abstract：BACKGROUND:Human papillomaviruses (HPVs) commonly cause proliferative lesions of squamous epithelia, and infection with certain HPV types carries a high risk of malignant transformation, especially in the uterine cervix but also at other sites, including the esophagus. We used molecular techniques to detect and type HP...

journal_title：Cancer

authors： West AB,Soloway GN,Lizarraga G,Tyrrell L,Longley JB

更新日期：1996-06-15 00:00:00

abstract：:BALB/c mice were hyperimmunized with ACHN (ATCC CRL 1611, American Type Culture Collection, Rockville, Maryland), a stable in vitro cell line derived from a malignant pleural effusion in a 22-year-old man with renal cell carcinoma. The hyperimmune spleen cells were fused with NS-1 murine myeloma cells using polyethyle...

journal_title：Cancer

authors： Kochevar J

更新日期：1987-06-15 00:00:00

abstract：:Chemokines are chemoattractant cytokines that regulate the trafficking and activation of leukocytes and other cell types under a variety of inflammatory and noninflammatory conditions. Over the past few years, studies have increasingly shown that chemokines play an important role in several aspects of tumor progressio...

journal_title：Cancer

authors： Ruffini PA,Morandi P,Cabioglu N,Altundag K,Cristofanilli M

更新日期：2007-06-15 00:00:00

abstract：:The myeloproliferative neoplasms (MPNs) essential thrombocythemia (ET), polycythemia vera (PV), and primary myelofibrosis (MF) are malignancies that frequently harbor the recurrent somatic point mutation JAK2(V617F). The discovery of this mutation has fueled the development of Janus kinase 2 (JAK2) inhibitors. Availab...

journal_title：Cancer

authors： Quintás-Cardama A,Verstovsek S

更新日期：2012-02-15 00:00:00

abstract：BACKGROUND:Patient navigation programs are emerging that aim to address disparities in clinical trial participation among medically underserved populations, including racial/ethnic minorities. However, there is a lack of consensus on the role of patient navigators within the clinical trial process as well as outcome me...

journal_title：Cancer

authors： Ghebre RG,Jones LA,Wenzel JA,Martin MY,Durant RW,Ford JG

更新日期：2014-04-01 00:00:00

abstract：:The clinical course of melanoma of the skin diagnosed during pregnancy was compared with a control population of women with melanoma that occurred during the childbearing years, as recorded by the Connecticut Tumor Registry. The survival at three and five years for the 12 patients whose melanoma developed during pregn...

journal_title：Cancer

authors： Houghton AN,Flannery J,Viola MV

更新日期：1981-07-15 00:00:00

abstract：BACKGROUND:Rising health care costs have caused providers to question the benefit of regular follow-up after treatment for patients with early stage cutaneous melanoma. The authors hypothesized that routine reassessment and careful education of these patients would facilitate earlier diagnosis of a subsequent second pr...

journal_title：Cancer

authors： DiFronzo LA,Wanek LA,Morton DL

更新日期：2001-04-15 00:00:00

abstract：BACKGROUND:Up to now, the expression of the tumor-associated Thomsen-Friedenreich (TF) antigen in colorectal carcinoma has not been thoroughly investigated with particular emphasis on its correlation with established clinicopathologic characteristics and classifications as well as its prognostic relevance. METHODS:For...

journal_title：Cancer

authors： Baldus SE,Zirbes TK,Hanisch FG,Kunze D,Shafizadeh ST,Nolden S,Mönig SP,Schneider PM,Karsten U,Thiele J,Hölscher AH,Dienes HP

更新日期：2000-04-01 00:00:00