Prognostic implications of patterns of failure for gastrointestinal leiomyosarcomas.

abstract：BACKGROUND:Recently, invasion of vascular spaces by endometrial carcinoma has received particular attention as a prognostic factor. The goal of the current investigation was to re-examine the effect of vascular invasion on tumor recurrence and survival in patients with endometrial carcinoma. METHODS:Surgical specimens...

journal_title：Cancer

authors： Inoue Y,Obata K,Abe K,Ohmura G,Doh K,Yoshioka T,Hoshiai H,Noda K

更新日期：1996-10-01 00:00:00

abstract：BACKGROUND:Nineteen patients with Ewing sarcoma of bone, each younger than 3 years of age at the time of initial presentation, are reported. These children represent an unusually young age group for documented Ewing sarcoma and represent 2.6% of all patients registered in the Intergroup Ewing's Sarcoma Study (IESS). M...

journal_title：Cancer

authors： Maygarden SJ,Askin FB,Siegal GP,Gilula LA,Schoppe J,Foulkes M,Kissane JM,Nesbit M

更新日期：1993-03-15 00:00:00

abstract：:Two hundred ninety-three patients with Stage IB carcinoma of the uterine cervix were treated by intracavitary irradiation followed by radical hysterectomy and pelvic lymph node dissection in the 3-year period 1970 to 1972, inclusive. Preoperative lymphography was performed and intraoperative films were taken to obtain...

journal_title：Cancer

authors： Kjorstad KE,Kolbenstvedt A,Strickert T

更新日期：1984-11-15 00:00:00

abstract：BACKGROUND:Angiotropic large cell lymphoma (ALCL) is characterized by the intravascular proliferation of malignant lymphoid cells in small and medium-sized blood vessels. In the current study, the authors report an unusual case in which the initial presentation of the ALCL was that of superior vena cava (SVC) syndrome....

journal_title：Cancer

authors： Savarese DM,Zavarin M,Smyczynski MS,Rohrer MJ,Hutzler MJ

更新日期：2000-12-15 00:00:00

abstract：:Elevated serum levels of carcinoembryonic antigen (CEA) were found in 70% of 141 patients with advanced gastrointestinal (GI) cancers. Serial CEA measurements were performed on 70 patients before and during chemotherapy. The majority were treated with 5-FU and Methyl-CCNU (33 patients), 5-FU (19 patients), or 5-FU and...

journal_title：Cancer

authors： Al-Sarraf M,Baker L,Talley RW,Kithier K,Vaitkevicius VK

更新日期：1979-10-01 00:00:00

abstract：BACKGROUND:Chemotherapy is known to cure a small minority of patients with acute myeloid leukemia (AML). Less is known about the risk of such patients developing subsequent cancers or about their ability to return to work. METHODS:The authors analyzed outcomes among 1892 patients who received treatment for newly diagn...

journal_title：Cancer

authors： Estey E,deLima M,Strom S,Pierce S,Freireich EJ,Keating MJ

更新日期：1997-12-01 00:00:00

abstract：BACKGROUND:Osteosarcomas are typically long bone tumors and rarely affect the skull, with most articles reporting single cases. As elsewhere in the body, these lesions may be classified as primary or secondary, chiefly post-Paget and post-radiation therapy. METHODS:The authors reviewed the osteosarcomas of the skull d...

journal_title：Cancer

authors： Salvati M,Ciappetta P,Raco A

更新日期：1993-04-01 00:00:00

abstract：:The glucose consumption rate of 9L rat brain tumor cells was determined as a function of concentration. Glucose uptake followed Michaelis-Menten kinetics with a Km of 0.58 mM and a Vmax of 1.6 pg/cell-min. The glucose diffusion coefficient in spheroids of 9L tumor cells was determined to be 1.5 x 10(-6) cm2/s at 37 de...

journal_title：Cancer

authors： Li CK

更新日期：1982-11-15 00:00:00

abstract：:DNA ploidy and percent of (%S-phase) S-phase cells were determined from the DNA content distribution of 21 benign and 76 malignant (69 primary, 7 metastatic) breast tumors using flow cytometry. All of the benign tumors were diploid, whereas 89% of the malignant tumors had measurable aneuploidy. Multiple stem-lines wer...

journal_title：Cancer

authors： Moran RE,Black MM,Alpert L,Straus MJ

更新日期：1984-10-15 00:00:00

abstract：BACKGROUND:Pelvic irradiation to patients with prostate cancer is accompanied by urinary and intestinal reactions. In men older than 60 years, treatment-induced problems should be evaluated in relation to problems in an age-matched nonirradiated population. METHODS:In the present study, problems in the urinary tract a...

journal_title：Cancer

authors： Widmark A,Fransson P,Tavelin B

更新日期：1994-11-01 00:00:00

abstract：:Carcinoembryonic antigen (CEA) values in 529 patients treated in two consecutive adjuvant chemotherapy protocols were analyzed to determine if CEA values correlated with disease-free status or prognostic utility. CEA values were evaluated preoperatively, before chemotherapy, at the conclusion of chemotherapy, and duri...

journal_title：Cancer

authors： Theriault RL,Hortobagyi GN,Fritsche HA,Frye D,Martinez R,Buzdar AU

更新日期：1989-03-01 00:00:00

abstract：BACKGROUND:In a randomized Phase II study, the authors evaluated the activity and toxicity of the new cisplatin, doxorubicin, and mitomycin C (PAM) combination, that includes cisplatin (P) instead of 5-fluorouracil as in the 5-fluorouracil, doxorubicin, and mitomycin C (FAM) combination, in patients with advanced gastr...

journal_title：Cancer

authors： De Lisi V,Cocconi G,Angelini F,Cavicchi F,Di Costanzo F,Gilli G,Rodinò C,Soldani M,Tonato M,Finardi C

更新日期：1996-01-15 00:00:00

abstract：BACKGROUND:Patients undergoing allogeneic hematopoietic stem cell transplantation (HSCT) for chronic myeloid leukemia (CML) are increasingly likely to have received a novel tyrosine kinase inhibitor (NTKI) after failing imatinib mesylate. It is unknown whether the use of these NTKIs before HSCT increases transplant-rel...

journal_title：Cancer

authors： Jabbour E,Cortes J,Kantarjian H,Giralt S,Andersson BS,Giles F,Shpall E,Kebriaei P,Champlin R,de Lima M

更新日期：2007-07-15 00:00:00

abstract：BACKGROUND:The development of malignancies in recipients of a cardiothoracic transplant (CTT)--that is, heart, lung, or heart and lung recipients-is of concern. Cutaneous and lymphoproliferative malignancies comprise the two major groups of malignancies encountered. A small subgroup of patients will develop potentially...

journal_title：Cancer

authors： Veness MJ,Quinn DI,Ong CS,Keogh AM,Macdonald PS,Cooper SG,Morgan GW

更新日期：1999-04-15 00:00:00

abstract：BACKGROUND:Leptomeningeal carcinomatosis (LC) represents a devastating complication of systemic cancer, and patients with LC have a dismal prognosis and increased mortality. The few studies that have focused on the evaluation of prognostic factors in patients with LC have resulted in contradictory results. Thus, the tr...

journal_title：Cancer

authors： Bruna J,González L,Miró J,Velasco R,Gil M,Tortosa A,Neuro-Oncology Unit of the Institute of Biomedical Investigation of Bellvitge.

更新日期：2009-01-15 00:00:00

abstract：BACKGROUND:Radiotherapy (XRT) is effective as the primary treatment modality for laryngopharyngeal cancer; however, complications of XRT can result in significant morbidity. Few previous studies have examined the effect of continued smoking on complications of XRT. The authors of this report hypothesized that patients ...

journal_title：Cancer

authors： Zevallos JP,Mallen MJ,Lam CY,Karam-Hage M,Blalock J,Wetter DW,Garden AS,Sturgis EM,Cinciripini PM

更新日期：2009-10-01 00:00:00

abstract：:The myeloproliferative neoplasms (MPNs) essential thrombocythemia (ET), polycythemia vera (PV), and primary myelofibrosis (MF) are malignancies that frequently harbor the recurrent somatic point mutation JAK2(V617F). The discovery of this mutation has fueled the development of Janus kinase 2 (JAK2) inhibitors. Availab...

journal_title：Cancer

authors： Quintás-Cardama A,Verstovsek S

更新日期：2012-02-15 00:00:00

abstract：:In 186 women with breast cancer, there was a progressive increase in the proportion of axillary nodal involvement as the number of pregnancies increased from zero to two or more (P = 0.026). Logistic regression analysis demonstrated that this effect was independent of the known relationship of age and tumor size to no...

journal_title：Cancer

authors： Lehrer S,Levine E,Savoretti P,Cropley J,Botstein C,Song HK,Mandell L,Shank B

更新日期：1992-02-15 00:00:00

abstract：:Comparison of 50 proliferating trichilemmal cysts with 50 "ordinary" trichilemmal cysts indicated that both types almost invariably occurred on the scalps of women, were diagnosed clinically as cysts, followed a benign course, and featured trichilemmal keratinization. A spectrum was observed from trichilemmal cyst wit...

journal_title：Cancer

authors： Brownstein MH,Arluk DJ

更新日期：1981-09-01 00:00:00

abstract：:The authors reviewed the liver histopathology and the clinical features of eight patients with liver metastases from colorectal cancer who were treated by hepatic arterial infusion chemotherapy (HAIC) via an implantable pump (Infusaid). Before HAIC, these patients had no evidence of hepatitis, and results of liver bio...

journal_title：Cancer

authors： Doria MI Jr,Shepard KV,Levin B,Riddell RH

更新日期：1986-08-15 00:00:00

abstract：:Twelve cases of ovarian adenocarcinoma were studied for alterations in proto-oncogenes, and a unique pattern of altered ras proto-oncogenes was observed. Amplification of ras-Ki was found in three of seven ovarian tumors and amplification of ras-Ha in one of 12. In contrast, ras-Ha amplification was not found in any o...

journal_title：Cancer

authors： Zhou DJ,Gonzalez-Cadavid N,Ahuja H,Battifora H,Moore GE,Cline MJ

更新日期：1988-10-15 00:00:00

abstract：BACKGROUND:Prognosis of patients with adenocarcinoma of the pancreatic body and tail is extremely poor. Anatomically, this part of the pancreas is thin, and cancerous invasion to the retropancreatic structures occurs easily. The majority of patients have residual tumor in the retroperitoneal tissues after conventional ...

journal_title：Cancer

authors： Ozaki H,Kinoshita T,Kosuge T,Yamamoto J,Shimada K,Inoue K,Koyama Y,Mukai K

更新日期：1996-06-01 00:00:00

abstract：BACKGROUND:Hepatectomy is the standard of care for patients with colorectal cancer who have isolated hepatic metastases; however, the long-term survival benefits of hepatectomy in this population have not been characterized well outside of case series. For the current study, a population-based database was used to comp...

journal_title：Cancer

authors： Cummings LC,Payes JD,Cooper GS

更新日期：2007-02-15 00:00:00

abstract：BACKGROUND:Quality of life (QOL) issues in patients with head and neck carcinoma are of importance beyond the incidence of these tumors because of the impact of the disease and its treatment on external appearance and function of the upper aerodigestive tract. Nasopharyngeal carcinoma (NPC) patients comprise a unique s...

journal_title：Cancer

authors： Talmi YP,Horowitz Z,Bedrin L,Wolf M,Chaushu G,Kronenberg J,Pfeffer MR

更新日期：2002-02-15 00:00:00

abstract：:The cellular DNA content of 15 benign and 34 malignant primary bone tumors was analyzed by means of flow cytophotometry. All benign tumors except one of questionable histologic type exhibited a normal DNA content (diploid), whereas 23 of 34 malignant tumors showed an abnormal DNA content (aneuploid). Closer analysis r...

journal_title：Cancer

authors： Kreicbergs A,Silvferswärd C,Tribukait B

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND:The identification of high risk patients with endometrial carcinoma is considered essential for individualized therapy to improve prognosis and avoid overtreatment. The goal of the current study was to investigate the prognostic value of nuclear morphometry, particularly for patients with localized endometri...

journal_title：Cancer

authors： Salvesen HB,Iversen OE,Akslen LA

更新日期：1998-09-01 00:00:00

abstract：BACKGROUND:A series of retrospective studies have reported that patients with human epidermal growth factor receptor 2(HER2)-positive breast cancer are at a greater risk of central nervous system (CNS) metastases. Trastuzumab, which does not cross the blood-brain barrier, has been associated with this increased risk. ...

journal_title：Cancer

authors： Musolino A,Ciccolallo L,Panebianco M,Fontana E,Zanoni D,Bozzetti C,Michiara M,Silini EM,Ardizzoni A

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:The prognostic impact of DNA mismatch repair (MMR) status remains controversial in patients with stage III colon cancer who are treated with adjuvant chemotherapy (AC). The aim of this study was to evaluate the survival outcome of AC in deficient mismatch repair (dMMR)/microsatellite instable (MSI) stage III...

journal_title：Cancer

authors： Shaib WL,Zakka KM,Jiang R,Yan M,Alese OB,Akce M,Wu C,Behera M,El-Rayes BF

更新日期：2020-09-15 00:00:00

abstract：:Nineteen adult patients with acute lymphoblastic leukemia were treated with combination chemotherapy to induce remission in the period from 1971 to 1979. Those patients achieving remission received intensive post-remission therapy with central nervous system (CNS) prophylaxis, followed by two-drug maintenance therapy,...

journal_title：Cancer

authors： Blacklock HA,Matthews JR,Buchanan JG,Ockelford PA,Hill RS

更新日期：1981-11-01 00:00:00

abstract：:Gonadal dosimetry and spermatogenic activity was monitored in patients given radiation therapy (RT) after unilateral orchiectomy for seminoma. The RT given was, with minor variations, 3200 rad in 16 fractions in four weeks to the para-aortic and ipsilateral pelvic inguinal lymphatics in order to include the orchiectom...

journal_title：Cancer

authors： Hahn EW,Feingold SM,Simpson L,Batata M

更新日期：1982-07-15 00:00:00