Improved survival from acute lymphoblastic leukemia in adolescents and adults.

abstract：BACKGROUND:Synovial sarcomas are high-grade soft tissue neoplasms often characterized by a biphasic spindle and epithelioid cell morphology. The majority of synovial sarcomas harbor a specific chromosomal translocation in which the proximal portion of the SYT gene at chromosome 18q11 is fused to the distal portion of o...

journal_title：Cancer

authors： Thomas DG,Giordano TJ,Sanders D,Biermann S,Sondak VK,Trent JC,Yu D,Pollock RE,Baker L

更新日期：2005-02-15 00:00:00

abstract：BACKGROUND:Bortezomib is a proteasome inhibitor with manageable clinical toxicity and laboratory evidence of anti-melanoma activity. Therefore, it was considered for clinical testing in patients with metastatic melanoma. METHODS:Patients with metastatic melanoma and adequate hematologic, renal, and hepatic function we...

journal_title：Cancer

authors： Markovic SN,Geyer SM,Dawkins F,Sharfman W,Albertini M,Maples W,Fracasso PM,Fitch T,Lorusso P,Adjei AA,Erlichman C

更新日期：2005-06-15 00:00:00

abstract：BACKGROUND:Sperm cryopreservation before cancer chemotherapy is available for young patients with cancer. However, few patients bank their sperm. The authors evaluated by questionnaire the psychological impact of sperm cryopreservation. METHODS:The authors cryopreserved the sperm of 111 patients with cancer for free a...

journal_title：Cancer

authors： Saito K,Suzuki K,Iwasaki A,Yumura Y,Kubota Y

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND:Disruption of the lymphatic circulation through breast carcinoma-associated axillary lymph node dissection, with or without radiation therapy, reportedly is the most common cause of lymphedema in developed countries. There is no cure for breast carcinoma-associated lymphedema. Although intermittent pneumatic...

journal_title：Cancer

authors： Szuba A,Achalu R,Rockson SG

更新日期：2002-12-01 00:00:00

abstract：METHODS:The diagnostic performance of transrectal ultrasound (TRUS) gland volume and prostate specific antigen (PSA) results were evaluated in 204 men consecutively scheduled to undergo transurethral prostatic resection (TUR). RESULTS:Nonpalpable prostate cancer was detected by TRUS alone in 18% (29 of 161) and by TUR...

journal_title：Cancer

authors： Lee F,Littrup PJ,Loft-Christensen L,Kelly BS Jr,McHugh TA,Siders DB,Mitchell AE,Newby JE

更新日期：1992-07-01 00:00:00

abstract：BACKGROUND:The goal of this study was to compare health-related quality of life (HRQL) from diagnosis to 10 years postdiagnosis among breast cancer survivors (BCS) and women without cancer over the same period and to identify BCS subgroups exhibiting different HRQL trajectories. METHODS:Our analysis included 141 BCS a...

journal_title：Cancer

authors： Avis NE,Levine B,Goyal N,Crawford SL,Hess R,Colvin A,Bromberger JT,Greendale GA

更新日期：2020-05-15 00:00:00

abstract：BACKGROUND:Optimal treatments for vulvar and vaginal melanomas (VVMs) have not been identified. Herein, the authors compare molecular profiles between VVM and nongynecologic melanoma (NGM) subtypes with the objective of identifying novel, targetable biomarkers. METHODS:In total, 2304 samples of malignant melanoma that...

journal_title：Cancer

authors： Hou JY,Baptiste C,Hombalegowda RB,Tergas AI,Feldman R,Jones NL,Chatterjee-Paer S,Bus-Kwolfski A,Wright JD,Burke WM

更新日期：2017-04-15 00:00:00

abstract：BACKGROUND:Assessment of the responses of osteosarcoma patients to preoperative chemotherapy is of clinical importance. The purpose of this study was to estimate the accuracy of angiography and thallium-201 scintigraphy, compared with histology, in assessing the responses of patients with osteosarcoma to preoperative c...

journal_title：Cancer

authors： Kunisada T,Ozaki T,Kawai A,Sugihara S,Taguchi K,Inoue H

更新日期：1999-09-15 00:00:00

abstract：BACKGROUND:Despite its established benefits, palliative care (PC) is rarely utilized for hematopoietic stem cell transplant (HSCT) patients. We sought to examine transplant physicians' perceptions of PC. METHODS:We conducted a cross-sectional survey of transplant physicians recruited from the American-Society-for-Bloo...

journal_title：Cancer

authors： El-Jawahri A,LeBlanc TW,Burns LJ,Denzen E,Meyer C,Mau LW,Roeland EJ,Wood WA,Petersdorf E

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:Colonoscopic screening has increased detection of malignant colonic polyps (MPs). The goal of this study was to analyze trends and patterns in the surgical treatment of MPs and to assess outcomes as measured by lymph node retrieval and patient survival. METHODS:The Surveillance, Epidemiology, and End Result...

journal_title：Cancer

authors： Wasif N,Etzioni D,Maggard MA,Tomlinson JS,Ko CY

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:In the United States, incidence rates for malignant tumors of the uterine corpus are lower among blacks than among whites, whereas mortality rates are higher among blacks. Reasons for the higher level of mortality among blacks have been debated. METHODS:Using data from the Surveillance, Epidemiology, and En...

journal_title：Cancer

authors： Sherman ME,Devesa SS

更新日期：2003-07-01 00:00:00

abstract：:Late side effects of chemotherapy were studied in 51 women who had received at least 300 mg of melphalan for ovarian cancer and had survived for at least three years. Hematologic, statistical, and cytogenetic methods were employed. Six cases of iatrogenic leukemia were found. They appeared to represent a hematologic e...

journal_title：Cancer

authors： Einhorn N,Eklund G,Franzén S,Lambert B,Lindsten J,Söderhäll S

更新日期：1982-06-01 00:00:00

abstract：BACKGROUND:The objective of this study was to characterize chronic disease, health-related quality of life (HRQOL), emotional distress, and social attainment among long-term survivors of neuroblastoma. METHODS:Chronic health conditions among 136 ≥10-year neuroblastoma survivors (median age, 31.9 years; range, 20.2-54....

journal_title：Cancer

authors： Wilson CL,Brinkman TM,Cook C,Huang S,Hyun G,Green DM,Furman WL,Bhakta N,Ehrhardt MJ,Krasin MJ,Robison LL,Ness KK,Hudson MM

更新日期：2020-03-15 00:00:00

abstract：BACKGROUND:Based on prior experience with dacarbazine (DTIC) and an outpatient interleukin-2 (IL-2) regimen, the current study was conducted to improve the antitumor efficacy and assess the immunologic interactions between chemotherapy and IL-2. METHODS:Thirty-two patients were registered onto a treatment program, whi...

journal_title：Cancer

authors： Flaherty LE,Robinson W,Redman BG,Gonzalez R,Martino S,Kraut M,Valdivieso M,Rudolph AR

更新日期：1993-06-01 00:00:00

abstract：:The predictive value of estrogen receptor (ER) level for response to chemotherapy was studied in 182 patients with metastatic breast cancer in a prospective study. Patients were stratified according to ER status and dominant site of disease and randomized to one of three regimens: cyclophosphamide, 5-Fluorouracil, and...

journal_title：Cancer

authors： Rosner D,Lane WW,Nemoto T

更新日期：1989-07-01 00:00:00

abstract：:The percentage of T lymphocytes that form rosettes (RFC) with sheep erythrocytes (E rosettes), cutaneous delayed-type hypersensitivity, and in vitro lymphocyte transformation was measured in 15 patients with primary intracranial tumors. The ability of T lymphocytes to form E rosettes was significantly impaired. Thes...

journal_title：Cancer

authors： Brooks WH,Roszman TL,Rogers AS

更新日期：1976-04-01 00:00:00

abstract：:Traditional therapy for malignant pleural effusions includes thoracentesis or tube drainage with instillation of irritants to achieve pleurodesis. This can require a lengthy hospitalization, causes pain and discomfort, and has an appreciable failure rate. Because of these drawbacks, the authors used a shunting device ...

journal_title：Cancer

authors： Little AG,Ferguson MK,Golomb HM,Hoffman PC,Vogelzang NJ,Skinner DB

更新日期：1986-12-15 00:00:00

abstract：BACKGROUND:The effect of adjuvant chemotherapy after resection of nonsmall cell lung cancer (NSCLC) remains an unresolved question. METHODS:From October, 1982, to November, 1986, 267 patients with resected NSCLC were included in a randomized trial. The adjuvant allocated treatments were either postoperative radiothera...

journal_title：Cancer

authors： Dautzenberg B,Chastang C,Arriagada R,Le Chevalier T,Belpomme D,Hurdebourcq M,Lebeau B,Fabre C,Charvolin P,Guérin RA

更新日期：1995-09-01 00:00:00

abstract：BACKGROUND:Some studies have suggested that the use of calcium channel blockers may increase the risk of cancer. A possible association of the use of calcium channel blockers with cancer incidence and cancer mortality was addressed using data from the Nurses' Health Study. METHODS:In this study, a total of 18,635 fema...

journal_title：Cancer

authors： Michels KB,Rosner BA,Walker AM,Stampfer MJ,Manson JE,Colditz GA,Hennekens CH,Willett WC

更新日期：1998-11-01 00:00:00

abstract：:A search of the records of 10 pediatric oncology centers revealed 102 children with more than one malignant neoplasm. In this group of 102 patients, all pediatric cancers were seen as initial lesions, but Wilms' tumor and retinoblastoma were over-represented and leukemia and brain tumors underrepresented. Survival var...

journal_title：Cancer

authors： Meadows AT,D'Angio GJ,Miké V,Banfi A,Harris C,Jenkin RD,Schwartz A

更新日期：1977-10-01 00:00:00

abstract：:Cancer is among the leading causes of morbidity and mortality in the Western world. Despite recent advances, most therapeutic approaches fail to eradicate the entire neoplastic clone. The remaining cells often develop metastasis and/or recurrences and therefore may represent attractive targets of therapy. A new exciti...

journal_title：Cancer

authors： Schulenburg A,Ulrich-Pur H,Thurnher D,Erovic B,Florian S,Sperr WR,Kalhs P,Marian B,Wrba F,Zielinski CC,Valent P

更新日期：2006-11-15 00:00:00

abstract：BACKGROUND:Ribonucleotide reductase M1 (RRM1) is an important molecule in different types of cancer. The objective of this study was to evaluate the predictive roles of RRM1 in the survival of patients with resectable pancreatic adenocarcinoma who received treatment with gemcitabine or nongemcitabine adjuvant therapy. ...

journal_title：Cancer

authors： Xie H,Jiang W,Jiang J,Wang Y,Kim R,Liu X,Liu X

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Methotrexate is a chemotherapeutic agent frequently utilized for the treatment of malignant, rheumatic, and pulmonary diseases. Although this agent has been extensively used for more than 45 years, there are few reports of immediate systemic hypersensitivity reactions. The reported immediate reactions includ...

journal_title：Cancer

authors： Alkins SA,Byrd JC,Morgan SK,Ward FT,Weiss RB

更新日期：1996-05-15 00:00:00

abstract：BACKGROUND:Synovial sarcoma usually arises in the extremities and in close proximity to large joints. Reported examples arising in the anterior abdominal wall are rare. Because most accounts from this location consist of case reports, neither clinical nor prognostic features have been well delineated. METHODS:Twenty-s...

journal_title：Cancer

authors： Fetsch JF,Meis JM

更新日期：1993-07-15 00:00:00

abstract：BACKGROUND:Nonsmall cell lung carcinomas (NSCLCs) are associated with very dismal prognoses, and adjuvant chemotherapy, including irinotecan, taxanes, platin, and vinca alkaloid derivatives, offer patients only slight clinical benefits. Part of the chemoresistance of NSCLC results from the expression in NSCLC cells of ...

journal_title：Cancer

authors： Mathieu A,Remmelink M,D'Haene N,Penant S,Gaussin JF,Van Ginckel R,Darro F,Kiss R,Salmon I

更新日期：2004-10-15 00:00:00

abstract：BACKGROUND:The development of malignancies in recipients of a cardiothoracic transplant (CTT)--that is, heart, lung, or heart and lung recipients-is of concern. Cutaneous and lymphoproliferative malignancies comprise the two major groups of malignancies encountered. A small subgroup of patients will develop potentially...

journal_title：Cancer

authors： Veness MJ,Quinn DI,Ong CS,Keogh AM,Macdonald PS,Cooper SG,Morgan GW

更新日期：1999-04-15 00:00:00

abstract：BACKGROUND:A Phase II study with carboplatin, methotrexate, and vinblastine (CAMV) was conducted with patients who had advanced urothelial cancer to investigate the activity and toxicity of carboplatin when used in combination chemotherapy. METHODS:Thirty-six patients with advanced urothelial cancer were treated with ...

journal_title：Cancer

authors： Boccardo F,Pace M,Guarneri D,Canobbio L,Curotto A,Martorana G

更新日期：1994-04-01 00:00:00

abstract：:This is a report of a gastric perforation secondary to a metastasis from a primary squamous cell carcinoma of the lung in a 70-year-old white man who was being treated with cimetidine for a presumed benign gastric ulcer. The literature concerning bronchogenic carcinoma metastasizing to the stomach and small bowel is r...

journal_title：Cancer

authors： Fletcher MS

更新日期：1980-10-15 00:00:00

abstract：:Interleukin-2 (IL2) is essential for the expansion of antigen-triggered lymphocytes and cytotoxic T-cells, processes necessary for tumor control that are frequently depressed in malignancy. The authors measured certain aspects of IL2 function in cancer patients and controls and correlated the findings with the general...

journal_title：Cancer

authors： Wanebo HJ,Pace R,Hargett S,Katz D,Sando J

更新日期：1986-02-01 00:00:00

abstract：BACKGROUND AND METHODS:A univariate and multivariate analysis for the correlation between histomorphologic factors and prognosis was made using data from 1116 patients with soft tissue sarcoma, including 1005 cases available with complete histologic and follow-up data. RESULTS:The overall 5-year survival rate was 43.6...

journal_title：Cancer

authors： Hashimoto H,Daimaru Y,Takeshita S,Tsuneyoshi M,Enjoji M

更新日期：1992-12-15 00:00:00