Leiomyosarcoma in the mediastinum presenting as superior vena cava syndrome.

abstract：BACKGROUND:Tamoxifen is a prototypic cancer chemopreventive agent, yet clinical trials have not evaluated its effect on mortality or the impact of drug pricing on its cost-effectiveness. METHODS:A state-transition Markov model for a hypothetical cohort of women age 50 years was used to evaluate the effects of tamoxife...

journal_title：Cancer

authors： Melnikow J,Kuenneth C,Helms LJ,Barnato A,Kuppermann M,Birch S,Nuovo J

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:p53 plays a critical role in cellular anticancer mechanisms, and has been correlated with second primary malignancy (SPM) development. A common polymorphism in codon 72 of p53 results in an amino acid substitution and could influence p53 function. The authors hypothesized that p53 codon 72 polymorphism may b...

journal_title：Cancer

authors： Li F,Sturgis EM,Chen X,Zafereo ME,Wei Q,Li G

更新日期：2010-05-15 00:00:00

abstract：:Gonadal dosimetry and spermatogenic activity was monitored in patients given radiation therapy (RT) after unilateral orchiectomy for seminoma. The RT given was, with minor variations, 3200 rad in 16 fractions in four weeks to the para-aortic and ipsilateral pelvic inguinal lymphatics in order to include the orchiectom...

journal_title：Cancer

authors： Hahn EW,Feingold SM,Simpson L,Batata M

更新日期：1982-07-15 00:00:00

abstract：BACKGROUND:Previous studies have shown that matrix metalloproteinase-2 (MMP-2) (a 72-kilodalton Type IV collagenase/gelatinase A) is associated with breast carcinoma, but to the authors' knowledge there are no reports showing that it is prognostic for overall survival. METHODS:Expression of the immunoreactive protein ...

journal_title：Cancer

authors： Talvensaari-Mattila A,Pääkkö P,Höyhtyä M,Blanco-Sequeiros G,Turpeenniemi-Hujanen T

更新日期：1998-09-15 00:00:00

abstract：:Activity of Poly (C) avid ribonuclease was estimated in sera of 129 patients with different malignancies. All patients had histologically verified carcinomas, normal renal function, and no signs of acute catabolic condition. Activity values were compared with those of normal subjects (U-test, Mann and Whitney) separat...

journal_title：Cancer

authors： Francesconi M,Meryn S,Rogan AM,Szalay S,Graninger W,Schmidbauer CP

更新日期：1984-05-01 00:00:00

abstract：BACKGROUND:Although it induces a relevant reduction in the risk of both visceral metastases and locoregional recurrences, the combination of chemotherapy and surgery only marginally improves the survival of patients with Stage IIIA(N2) (International Union Against Cancer staging and classification system) nonsmall-cell...

journal_title：Cancer

authors： Andre F,Grunenwald D,Pujol JL,Girard P,Dujon A,Brouchet L,Brichon PY,Westeel V,Le Chevalier T

更新日期：2001-06-15 00:00:00

abstract：:All patients with a diagnosis of cutaneous malignant melanoma (CMM) in Western Australia from 1980 to 1981 were observed for up to 6 years to determine vital status and to detect the development of local recurrences of the primary lesion. Approximately 35% of all patients had their tumors excised with surgical margins...

journal_title：Cancer

authors： Heenan PJ,English DR,Holman CD,Armstrong BK

更新日期：1992-01-15 00:00:00

abstract：:The case of a patient who underwent a left lower lobe lobectomy for adenocarcinoma of the lung and developed a metachronous squamous cell carcinoma of the right lung eight years later, is presented. The unusual nature of the case is emphasized utilizing a review of the literature. The criteria for diagnosing metachron...

journal_title：Cancer

authors： Coffman B,Crum E,Forman WB

更新日期：1983-01-01 00:00:00

abstract：:Using a modified Feulgen hydrolysis procedure and integrating microdensitometry, the acid-labile nuclear DNA in exfoliated cervical epithelial cells was quantified in a range of histologically confirmed cervical intraepithelial neoplasia (CIN), invasive cancer, and normal controls. The mean relative optical densities ...

journal_title：Cancer

authors： Partington CK,Sincock AM,Steele SJ

更新日期：1991-06-15 00:00:00

abstract：BACKGROUND:There is concern that antioxidant supplement use during chemotherapy and radiation therapy may decrease treatment effects, yet the effects of such supplements on recurrence and survival are largely unknown. METHODS:The authors prospectively examined the associations between antioxidant use after breast canc...

journal_title：Cancer

authors： Greenlee H,Kwan ML,Kushi LH,Song J,Castillo A,Weltzien E,Quesenberry CP Jr,Caan BJ

更新日期：2012-04-15 00:00:00

abstract：BACKGROUND:Assessment of prognostic markers in breast cancer independent of the axillary lymph node status is of major concern for the application of adjuvant treatment regimens. The current treatment decision is based mainly on the axillary lymph node status. Because of improved screening methods, the number and propo...

journal_title：Cancer

authors： Friedrichs K,Gluba S,Eidtmann H,Jonat W

更新日期：1993-12-15 00:00:00

abstract：:Androgen deprivation therapy (ADT) is now a well-established standard of care in combination with definitive radiotherapy for patients with unfavorable intermediate-risk to high-risk locally advanced prostate cancer. It is also well established that combination modality treatment with ADT and radiotherapy is superior ...

journal_title：Cancer

authors： Roach M 3rd

更新日期：2014-06-01 00:00:00

abstract：:The role of the adult oncologists in the area of pediatric cancer treatment previously has been unmeasured. A questionnaire bearing regarding the practice of 447 adult oncologists was administered in June 1991. The membership list of the Association of Community Cancer Centers was used to identify contact oncologists....

journal_title：Cancer

authors： Brady AM,Harvey C

更新日期：1993-05-15 00:00:00

abstract：:Two-hundred-four patients with previously untreated adenocarcinoma of rectum, rectosigmoid, and sigmoid colon were retrospectively evaluated to determine patterns of recurrence following curative resection. Seventy-eight (38%) subsequently developed recurrent disease. Of these, 40% (31/78) presented with local recurre...

journal_title：Cancer

authors： Rao AR,Kagan AR,Chan PM,Gilbert HA,Nussbaum H,Hintz BL

更新日期：1981-09-15 00:00:00

abstract：BACKGROUND:Wild-type p53 protein activates the WAF1/CIP-1 (p21) gene, leading to G1 arrest after DNA damage. The authors investigated the relation of p21 and p53 expression in pancreatic adenocarcinomas to disease stage, overall patient survival, and survival when chemotherapy or radiation therapy was given. METHODS:P...

journal_title：Cancer

authors： Dergham ST,Dugan MC,Joshi US,Chen YC,Du W,Smith DW,Arlauskas P,Crissman JD,Vaitkevicius VK,Sarkar FH

更新日期：1997-08-01 00:00:00

abstract：:The role of 99mTc-pertechnetate thyroid imaging in the preoperative assessment of patients with single palpable thyroid nodules was evaluated. The frequency of cancer in hypofunctional nodules was similar to that found in previous studies with 131I. The 99mTc-pertechnetate image allowed a reliable separation of pathol...

journal_title：Cancer

authors： Alderson PO,Sumner HW,Siegel BA

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND:Sunitinib has replaced interferon (IFN) as a first-line standard of care in the treatment of metastatic renal cell carcinoma (RCC). This study aimed to determine overall survival and to confirm effectiveness in a population that includes poor prognosis patients. METHODS:Data were collected on all patients i...

journal_title：Cancer

authors： Heng DY,Chi KN,Murray N,Jin T,Garcia JA,Bukowski RM,Rini BI,Kollmannsberger C

更新日期：2009-02-15 00:00:00

abstract：BACKGROUND:To describe continuing care and rehabilitation needs of cancer patients, a longitudinal design (6 months) was performed among patients 50 years of age and older with solid tumors. The study examined how age, type of treatment, site of cancer, and symptom experience affect physical functioning and their menta...

journal_title：Cancer

authors： Given CW,Given BA,Stommel M

更新日期：1994-10-01 00:00:00

abstract：BACKGROUND:Several studies have shown that lysophosphatidic acid (LPA), a phospholipidic chemical mediator, is relevant to the pathogenesis of ovarian carcinoma. Higher plasma levels of LPA have been reported in patients with ovarian carcinoma than in healthy patients, and LPA is known to activate ovarian carcinoma cel...

journal_title：Cancer

authors： Tokumura A,Tominaga K,Yasuda K,Kanzaki H,Kogure K,Fukuzawa K

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:The unusual clinical picture of transitional cell carcinoma (TCC) in Taiwan appears to be different from that reported elsewhere. METHODS:The authors reviewed their experience of 135 cases of pathologically proven TCC of the upper urinary tract. Data regarding the gender ratio and clinical presentation were...

journal_title：Cancer

authors： Chou YH,Huang CH

更新日期：1999-03-15 00:00:00

abstract：BACKGROUND:Recombinant tumor necrosis factor-alpha (rTNF-alpha) is a highly potential antineoplastic agent. However, its systemic administration in humans has resulted in a life-threatening septic shock-like syndrome, and its use has been abandoned. The administration of high dose rTNF-alpha and melphalan via isolated ...

journal_title：Cancer

authors： Gutman M,Inbar M,Lev-Shlush D,Abu-Abid S,Mozes M,Chaitchik S,Meller I,Klausner JM

更新日期：1997-03-15 00:00:00

abstract：BACKGROUND:Despite the characteristic histopathologic appearance of alveolar soft-part sarcoma (ASPS), its histogenesis remains unclear, and cytogenetic analysis of ASPS is limited to eight cases so far because of the extreme rarity of this disease. METHODS:The authors document a cytogenetic study of a primary case of...

journal_title：Cancer

authors： Joyama S,Ueda T,Shimizu K,Kudawara I,Mano M,Funai H,Takemura K,Yoshikawa H

更新日期：1999-10-01 00:00:00

abstract：:The ganglioside composition of neuroblastoma samples from 53 patients was determined. Tumor sites included the adrenals (15), and the thoracic (20), abdominal (15), and pelvic (3) areas. Age of the patients at the time of surgery ranged from 1 day to over 10 years and the Stage of the tumors from A to D. Differences i...

journal_title：Cancer

authors： Schengrund CL,Repman MA,Shochat SJ

更新日期：1985-12-01 00:00:00

abstract：BACKGROUND:Small cell glioblastoma (GBM) is a variant with monomorphous, deceptively bland nuclei that often is misdiagnosed as anaplastic oligodendroglioma. METHODS:To elucidate its clinicopathologic and genetic features, the authors studied 71 adult patients (median age, 57 years), including 22 patients who were ide...

journal_title：Cancer

authors： Perry A,Aldape KD,George DH,Burger PC

更新日期：2004-11-15 00:00:00

abstract：:A case of primary non-Hodgkin's lymphoma of the breast was studied with light and electron microscopy and for immunologic cell markers. With light microscopy, the tumor was seen to be a poorly differentiated lymphocytic lymphoma, diffuse, according to Rappaport's classification. With electron microscopy, the tumor was...

journal_title：Cancer

authors： Tateno M,Yoshiki T,Itoh T,Takamuro M,Saito C

更新日期：1983-08-15 00:00:00

abstract：:Tumor cell DNA (ploidy) content was measured prospectively in samples from 320 patients resected for colorectal cancer with a minimum follow-up time of 2 years. All patients were followed and those with recurrence were investigated carefully. There was no correlation between tumors with an abnormal cellular DNA conten...

journal_title：Cancer

authors： Armitage NC,Ballantyne KC,Sheffield JP,Clarke P,Evans DF,Hardcastle JD

更新日期：1991-05-15 00:00:00

abstract：BACKGROUND:Recent clinical trials support adding ovarian suppression (OS) to oral endocrine therapy (ET) for premenopausal women with early breast cancer. The adoption of OS among real-world populations and the impact of OS on ET adherence have not been evaluated. METHODS:This study examined a retrospective, observati...

journal_title：Cancer

authors： Reeder-Hayes KE,Mayer SE,Lund JL

更新日期：2021-01-28 00:00:00

abstract：BACKGROUND:Previous data from the National Cancer Data Base have examined time trends in stage of disease, treatment patterns, and survival for selected cancers. The most current (1993) data for breast carcinoma are described here. METHODS:Five Calls for Data have yielded a total of 508,724 breast cancer cases diagnos...

journal_title：Cancer

authors： Winchester DP,Osteen RT,Menck HR

更新日期：1996-10-15 00:00:00

abstract：:Three cases of pulmonary lymphangiomyomatosis are described, with emphasis on the ultrastructural changes. The clinicopathologic features corresponded to those previously described. Each patient was a female in the reproductive years; breathlessness and recurrent pneumothoraces were the predominant clinical features. ...

journal_title：Cancer

authors： Basset F,Soler P,Marsac J,Corrin B

更新日期：1976-12-01 00:00:00

abstract：BACKGROUND:Immediate or early postmastectomy breast reconstruction is performed infrequently. To the authors' knowledge, little is known regarding surgeon or patient perspectives on reconstruction treatment decisions. The purpose of the current study was to identify patient attitudes and preferences associated with bre...

journal_title：Cancer

authors： Morrow M,Mujahid M,Lantz PM,Janz NK,Fagerlin A,Schwartz K,Liu L,Deapen D,Salem B,Lakhani I,Katz SJ

更新日期：2005-12-01 00:00:00