Accelerated growth rates of recurrent hepatocellular carcinoma after liver transplantation.

abstract：BACKGROUND:Recently, the authors identified molecular signatures and pathways associated with nonsmall cell lung carcinoma histology and lung development. They hypothesized that genetic classifiers of histology would provide insight into lung tumorigenesis and would be associated with clinical outcome when evaluated in...

journal_title：Cancer

authors： Shah L,Walter KL,Borczuk AC,Kawut SM,Sonett JR,Gorenstein LA,Ginsburg ME,Steinglass KM,Powell CA

更新日期：2004-10-01 00:00:00

abstract：BACKGROUND:Flow cytometric analysis of trophoblastic tissue has shown that most partial hydatidiform moles (PMs) are triploid, whereas most complete moles (CMs) are diploid or tetraploid. Ploidy analysis can support a diagnosis of CM or PM. However, in some cases, a precise diagnosis cannot be rendered. METHODS:This s...

journal_title：Cancer

authors： Bocklage TJ,Smith HO,Bartow SA

更新日期：1994-06-01 00:00:00

abstract：:With endometrial adenocarcinoma, several factors, such as stage and histologic grade, are well recognized as having prognostic significance. Other variables, e.g., nuclear grade, probably are also important clinically. A preliminary investigation of the prognostic value of the ploidy, cell cycle kinetics, and sex ster...

journal_title：Cancer

authors： Geisinger KR,Homesley HD,Morgan TM,Kute TE,Marshall RB

更新日期：1986-10-01 00:00:00

abstract：BACKGROUND:Socioeconomic status represents an established barrier to health care access. Age, sex, and race may also play a role. The authors examined whether these affect the access to high-volume hospitals for uro-oncologic procedures in the United States. METHODS:Within the Nationwide Inpatient Sample (NIS), the au...

journal_title：Cancer

authors： Trinh QD,Sun M,Sammon J,Bianchi M,Sukumar S,Ghani KR,Jeong W,Dabaja A,Shariat SF,Perrotte P,Agarwal PK,Rogers CG,Peabody JO,Menon M,Karakiewicz PI

更新日期：2012-09-15 00:00:00

abstract：BACKGROUND:Treatment with traditional cytotoxic chemotherapy regimens containing streptozocin or dacarbazine has resulted in only marginal benefit for patients with metastatic neuroendocrine tumors. The use of these regimens has been further limited by their potential toxicity. Gemcitabine is generally well tolerated a...

journal_title：Cancer

authors： Kulke MH,Kim H,Clark JW,Enzinger PC,Lynch TJ,Morgan JA,Vincitore M,Michelini A,Fuchs CS

更新日期：2004-09-01 00:00:00

abstract：:Seven children with advanced nasopharyngeal carcinoma younger than 20 years of age diagnosed between 1975 and 1986 (inclusive) were treated with a uniform adjuvant chemotherapy regimen, which consisted of vincristine (1.5 mg/m2; day 1), doxorubicin (45 mg/m2; day 1), 5-fluorouracil (8 mg/kg; days 1 through 5), and cyc...

journal_title：Cancer

authors： Kim TH,McLaren J,Alvarado CS,Wyly JB,Crocker I,Winn K,Singhapakdi S,Ragab A

更新日期：1989-05-15 00:00:00

abstract：BACKGROUND:Podoplanin is a mucin-like glycoprotein that is important in lymphangiogenesis but not blood vessel formation. Recent studies suggested a potential role of podoplanin in certain tumor cells. The purpose of the current study was to determine the role of podoplanin in head and neck squamous cell carcinoma (HNS...

journal_title：Cancer

authors： Yuan P,Temam S,El-Naggar A,Zhou X,Liu DD,Lee JJ,Mao L

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:Transforming growth factor beta (TGFbeta) is important in colorectal cancer (CRC) progression. Bone morphogenetic proteins (BMPs), a subgroup within the TGFbeta superfamily, recently also have been implicated in CRC, but their precise role in CRC has yet to be investigated. METHODS:The authors used a tissue...

journal_title：Cancer

authors： Kodach LL,Bleuming SA,Musler AR,Peppelenbosch MP,Hommes DW,van den Brink GR,van Noesel CJ,Offerhaus GJ,Hardwick JC

更新日期：2008-01-15 00:00:00

abstract：BACKGROUND:The experience of one institution in treating soft tissue sarcomas of the head and neck in a pediatric population is presented. METHODS:Case materials of 134 patients younger than 20 years who were referred to the University of Texas M. D. Anderson Cancer Center between 1970 and 1989 for treatment of sarcom...

journal_title：Cancer

authors： Lyos AT,Goepfert H,Luna MA,Jaffe N,Malpica A

更新日期：1996-01-01 00:00:00

abstract：:Flow cytometry was used to compare binding of wheat germ agglutinin (WGA) and Lens culinaris lectin (Lcl) to peripheral lymphocytes (PBL) from normal subjects and 26 patients with chronic lymphocytic leukemia (CLL). As defined by the interactions of WGA and Lcl with cell surface receptors, normal unfractionated PBL an...

journal_title：Cancer

authors： Boldt DH,Nelson MO

更新日期：1983-06-01 00:00:00

abstract：:Primary splenic angiosarcomas are rare neoplasms. The diagnosis can only be made at surgery. Splenectomy prior to rupture prolongs survival. An unusual case report is presented and the literature reviewed. ...

journal_title：Cancer

authors： Smith VC,Eisenberg BL,McDonald EC

更新日期：1985-04-01 00:00:00

abstract：BACKGROUND:The echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase (EML4-ALK) fusion gene resulting from the chromosome inversion inv(2)(p21;p23) recently was identified in nonsmall cell lung cancer (NSCLC). The authors of this study investigated the frequency, genetic and clinicopathologic prof...

journal_title：Cancer

authors： Wong DW,Leung EL,So KK,Tam IY,Sihoe AD,Cheng LC,Ho KK,Au JS,Chung LP,Pik Wong M,University of Hong Kong Lung Cancer Study Group.

更新日期：2009-04-15 00:00:00

abstract：BACKGROUND:The clinical relevance of DNA image cytometry (ICM) and flow cytometry (FCM) remains under investigation in breast carcinoma. The objective of the current work was to study the prognostic value of DNA ICM and FCM in a series of patients randomized in a control trial. A multivariate analysis has been performe...

journal_title：Cancer

authors： Mandard AM,Denoux Y,Herlin P,Duigou F,van De Vijver MJ,Clahsen PC,van Den Broek L,Sahmoud TM,Henry-Amar M,van De Velde CJ

更新日期：2000-10-15 00:00:00

abstract：:The prognostic significance of the pretreatment growth characteristics of marrow blasts was examined in 37 patients with acute nonlymphocytic leukemia (ANLL) treated with a similar therapeutic regimen. Initial mitotic index (MI) and in vitro 3H-thymidine labeling index (LI) were broadly distributed showing no correlat...

journal_title：Cancer

authors： Amadori S,Petti MC,De Francesco A,Chierichini A,Mastrovincenzo C,Testa MG,Mandelli F

更新日期：1978-03-01 00:00:00

abstract：:Pancreatic carcinomas have been induced in Wistar and W/LEW rats by administration of total azaserine doses of 150-520 mg/kg by injection or oral routes over periods of 5-52 weeks. The latent period for development of invasive carcinomas was 1-2 years, but focal abnormalities in acinar cells appear earlier. The incide...

journal_title：Cancer

authors： Longnecker DS,Roebuck BD,Yager JD Jr,Lilja HS,Siegmund B

更新日期：1981-03-15 00:00:00

abstract：BACKGROUND:Breast cancer advocacy movements, driven by advocate-led civil society organizations (CSOs), have proven to be a powerful force for the advancement of cancer control in high-income countries (HICs). However, although patient advocacy movements are growing in low-income and middle-income countries (LMICs) in ...

journal_title：Cancer

authors： Dvaladze A,Kizub DA,Cabanes A,Nakigudde G,Aguilar B,Zujewski JA,Duggan C,Anderson BO,Pritam Singh RK,Gralow JR

更新日期：2020-05-15 00:00:00

abstract：BACKGROUND:Aberrant expression of the facilitative glucose transporter, GLUT1, is found in a wide spectrum of epithelial malignancies. The current study describes an immunohistochemical study of GLUT1 expression in benign, hyperplastic, and malignant endometrial epithelia. METHODS:One hundred sixteen formalin fixed, p...

journal_title：Cancer

authors： Wang BY,Kalir T,Sabo E,Sherman DE,Cohen C,Burstein DE

更新日期：2000-06-15 00:00:00

abstract：:Elective irradiation of sites of potential occult tumor spread is often part of a patient's radiation therapy program. The required radiation dose (D) depends on the probability that occult disease exists (P(occ)), the number of sites at risk (A), the number of tumor clonogens present (Ni), their radiation sensitivity...

journal_title：Cancer

authors： Marks LB

更新日期：1990-12-15 00:00:00

abstract：BACKGROUND:In Japan, where liver transplantation has not been used to treat patients with hepatocellular carcinoma (HCC), percutaneous ethanol injection (PEI) has been employed for those with small HCCs that are not amenable to surgical resection. In the current study, the authors evaluated PEI as a treatment for HCC p...

journal_title：Cancer

authors： Hasegawa S,Yamasaki N,Hiwaki T,Sako K,Komorizono Y,Baba Y,Imamura Y,Kubozono O,Yoshida A,Arima T

更新日期：1999-11-01 00:00:00

abstract：:As resources become increasingly scarce, oncology professionals and consumers of oncology services are increasingly engaging in advocacy efforts to achieve goals in cancer control. Effective advocacy includes both legislative and direct educational efforts. ...

journal_title：Cancer

authors： Berkman B,Stevenson E,Cravedi KG,Davis A,Lawrence W Jr,Mor V,Ostrander V,Rubenstein LJ,Speers M,Wilson K

更新日期：1991-12-01 00:00:00

abstract：BACKGROUND:Patients' estimates of their chances of therapeutic benefit from participation in early phase trials greatly exceed historical data. Ethicists worry that this therapeutic misestimation undermines the validity of informed consent. METHODS:The authors interviewed 45 patients enrolled in phase 1 or 2 oncology ...

journal_title：Cancer

authors： Sulmasy DP,Astrow AB,He MK,Seils DM,Meropol NJ,Micco E,Weinfurt KP

更新日期：2010-08-01 00:00:00

abstract：:Breast cancer is serious public health problem in countries of all resource levels. Although major advances in the detection and treatment of the disease have occurred in higher income settings, similar progress has been slow or scarce in most low- and middle-income countries (LMCs). The poorer outcomes in LMCs may re...

journal_title：Cancer

authors： Harford J,Azavedo E,Fischietto M,Breast Health Global Initiative Healthcare Systems Panel.

更新日期：2008-10-15 00:00:00

abstract：BACKGROUND:A National Institutes of Health (NIH) Consensus Development Conference on the treatment of patients with early stage invasive breast carcinoma, held in June 1990, recommended breast conservation therapy for the majority of women with Stage I or II breast carcinoma. The authors evaluated the national use of b...

journal_title：Cancer

authors： Lazovich D,Solomon CC,Thomas DB,Moe RE,White E

更新日期：1999-08-15 00:00:00

abstract：BACKGROUND:The first step of colorectal carcinoma spread depends on the ability of the tumor cells to degrade and invade the extracellular matrix (ECM). The objectives of the current study were to evaluate the serum pattern of laminin, C-terminal peptide of Type I (PIP), and N-terminal peptide of Type III (PIIIP) proco...

journal_title：Cancer

authors： Plebani M,Basso D,Roveroni G,De Paoli M,Galeotti F,Corsini A

更新日期：1997-04-01 00:00:00

abstract：:The National Comprehensive Cancer Network (NCCN) describes the presence of extracapsular spread and/or positive margins in oropharynx cancer (OPC) as an indication for the addition of chemotherapy to postoperative radiation. The guideline's category 1 consensus is based on what they term high-level evidence. For this ...

journal_title：Cancer

authors： Sinha P,Piccirillo JF,Kallogjeri D,Spitznagel EL,Haughey BH

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:The Akt/mammalian target of rapamycin (mTOR) pathway mediates cell survival and proliferation and contributes to tumor progression. Soft tissue leiomyosarcoma continues to show poor prognosis, and little is known about its mechanisms of tumor progression. Here the authors investigated the significance of act...

journal_title：Cancer

authors： Setsu N,Yamamoto H,Kohashi K,Endo M,Matsuda S,Yokoyama R,Nishiyama K,Iwamoto Y,Dobashi Y,Oda Y

更新日期：2012-03-15 00:00:00

abstract：:Clinical and pharmacokinetic studies were performed regarding the toxicity of methyl 6-[3-(2-chloroethyl)-3-nitrosoureido]-6-deoxy-alpha-D-glucopyranoside (MCNU) with other drugs, in conjunction with a peripheral blood stem cell autograft (PBSCT), for treating 26 children with acute leukemia or lymphoma associated wit...

journal_title：Cancer

authors： Takaue Y,Watanabe T,Hoshi Y,Abe T,Matsunaga K,Saito S,Hirao A,Kawano Y,Ninomiya T,Kuroda Y

更新日期：1991-04-01 00:00:00

abstract：BACKGROUND:The diagnosis of melanomas at an early stage is associated with improved survival, so the recognition of changes in pigmented skin lesions over time is important. We have developed a computer imaging system with the aim of assisting clinicians in differentiating early melanomas from benign pigmented skin les...

journal_title：Cancer

authors： Aitken JF,Pfitzner J,Battistutta D,O'Rourke PK,Green AC,Martin NG

更新日期：1996-07-15 00:00:00

abstract：BACKGROUND:Prognostic markers for renal cell carcinoma (RCC), such as patient symptoms, tumor stage, tumor size, and tumor grade, are useful for determining appropriate follow-up and selecting patients for adjuvant therapy. Histologic coagulative tumor necrosis, also reported to be a prognostic marker for RCC, has not ...

journal_title：Cancer

authors： Sengupta S,Lohse CM,Leibovich BC,Frank I,Thompson RH,Webster WS,Zincke H,Blute ML,Cheville JC,Kwon ED

更新日期：2005-08-01 00:00:00

abstract：:The development of resistance to purine analogs defines a poor-risk subset of patients with chronic lymphocytic leukemia (CLL). Although in recent years chemoimmunotherapeutic combinations such as fludarabine, cyclophosphamide, and rituximab have induced response rates of 95% in previously untreated patients and incre...

journal_title：Cancer

authors： Tsimberidou AM,Keating MJ

更新日期：2009-07-01 00:00:00