Mesenchymal stem cell homing: the devil is in the details.

Abstract:

:The study of MSC trafficking is clinically relevant for minimally invasive cell therapy to promote regeneration of damaged tissue, to treat inflammation, and to promote angiogenesis. However, these studies are complicated by the diverse methods used to culture, characterize, and deliver MSCs and by the variety of methods used to assess homing events. This review provides a critical analysis of the methods used to track homing of exogenously infused MSCs and discusses strategies for enhancing their trafficking to particular tissues.

journal_name

Cell Stem Cell

journal_title

Cell stem cell

authors

Karp JM,Leng Teo GS

doi

10.1016/j.stem.2009.02.001

subject

Has Abstract

pub_date

2009-03-06 00:00:00

pages

206-16

issue

3

eissn

1934-5909

issn

1875-9777

pii

S1934-5909(09)00056-3

journal_volume

4

pub_type

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