Abstract：
:In Nature Medicine, Pollyea et al. (2018) recently reported a remarkable overall response of newly diagnosed elderly acute myeloid leukemia patients to a venetoclax and azacitidine combination in a new clinical trial. This treatment reduced succinate dehydrogenase glutathionylation, impaired the tricarboxylic acid cycle, and depleted ATP in leukemia stem cells.
journal_name
Cell Stem Celljournal_title
Cell stem cellauthors
Nakada Ddoi
10.1016/j.stem.2018.12.005subject
Has Abstractpub_date
2019-01-03 00:00:00pages
7-8issue
1eissn
1934-5909issn
1875-9777pii
S1934-5909(18)30595-2journal_volume
24pub_type
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