当前位置： SCI文献检索 > Cell Stem Cell期刊下所有文献 > Stress Can Be a Good Thing for Blood Formation.

Stress Can Be a Good Thing for Blood Formation.

Abstract：

:Like politics, most developmental signals are local. However, in this issue of Cell Stem Cell, Kwan et al. (2016) and colleagues describe how a stress-induced signal that originates in the zebrafish brain promotes the formation of blood at a distant site, the dorsal aorta.

journal_name

Cell Stem Cell

journal_title

Cell stem cell

authors

Speck NA

doi

10.1016/j.stem.2016.08.011

subject

Has Abstract

pub_date

2016-09-01 00:00:00

pages

279-80

issue

3

eissn

1934-5909

issn

1875-9777

pii

S1934-5909(16)30258-2

journal_volume

19

pub_type

评论,杂志文章

相关文献

Cell Stem Cell文献大全
  • Distinguishing mast cell and granulocyte differentiation at the single-cell level.

    abstract：:The lineage restriction of prospectively isolated hematopoietic progenitors has been traditionally assessed by bulk in vitro culture and transplantation of large number of cells in vivo. These methods, however, cannot distinguish between homogenous multipotent or heterogeneous lineage-restricted populations. Using clo...

    journal_title：Cell stem cell

    pub_type： 杂志文章

    doi：10.1016/j.stem.2010.02.013

    authors： Franco CB,Chen CC,Drukker M,Weissman IL,Galli SJ

    更新日期：2010-04-02 00:00:00

  • Inhibition of Apoptosis Overcomes Stage-Related Compatibility Barriers to Chimera Formation in Mouse Embryos.

    abstract：:Cell types more advanced in development than embryonic stem cells, such as EpiSCs, fail to contribute to chimeras when injected into pre-implantation-stage blastocysts, apparently because the injected cells undergo apoptosis. Here we show that transient promotion of cell survival through expression of the anti-apoptot...

    journal_title：Cell stem cell

    pub_type： 杂志文章

    doi：10.1016/j.stem.2016.10.013

    authors： Masaki H,Kato-Itoh M,Takahashi Y,Umino A,Sato H,Ito K,Yanagida A,Nishimura T,Yamaguchi T,Hirabayashi M,Era T,Loh KM,Wu SM,Weissman IL,Nakauchi H

    更新日期：2016-11-03 00:00:00

  • Molecules that promote or enhance reprogramming of somatic cells to induced pluripotent stem cells.

    abstract：:Reprogramming of somatic cells to induced pluripotent stem cells (iPSCs) can be achieved by viral-mediated transduction of defined transcription factors. Moving toward the eventual goal of clinical application, it is necessary to overcome limitations such as low reprogramming efficiency and genomic alterations due to ...

    journal_title：Cell stem cell

    pub_type： 杂志文章,评审

    doi：10.1016/j.stem.2009.03.005

    authors： Feng B,Ng JH,Heng JC,Ng HH

    更新日期：2009-04-03 00:00:00

  • Fate restriction and multipotency in retinal stem cells.

    abstract：:Stem cells have the capacity to both self-renew and generate postmitotic cells. Long-term tracking of individual clones in their natural environment constitutes the ultimate way to validate postembryonic stem cells. We identify retinal stem cells (RSCs) using the spatiotemporal organization of the fish retina and foll...

    journal_title：Cell stem cell

    pub_type： 杂志文章

    doi：10.1016/j.stem.2011.11.004

    authors： Centanin L,Hoeckendorf B,Wittbrodt J

    更新日期：2011-12-02 00:00:00

  • Bringing a Leukemic Stem Cell Gene Signature into Clinics: Are We There Yet?

    abstract：:Prognostic markers that capture leukemia stem cell (LSC) activity can be useful for the risk stratification of acute myeloid leukemia (AML) patients. In a recent issue of Nature, Ng et al. (2016) develop a prognostic score based on a 17-gene expression signature of LSCs to predict outcome in AML patients. ...

    journal_title：Cell stem cell

    pub_type： 评论,杂志文章

    doi：10.1016/j.stem.2017.02.010

    authors： Richard-Carpentier G,Sauvageau G

    更新日期：2017-03-02 00:00:00

  • An ERK-Dependent Feedback Mechanism Prevents Hematopoietic Stem Cell Exhaustion.

    abstract：:Hematopoietic stem cells (HSCs) sustain hematopoiesis throughout life. HSCs exit dormancy to restore hemostasis in response to stressful events, such as acute blood loss, and must return to a quiescent state to prevent their exhaustion and resulting bone marrow failure. HSC activation is driven in part through the pho...

    journal_title：Cell stem cell

    pub_type： 杂志文章

    doi：10.1016/j.stem.2018.05.003

    authors： Baumgartner C,Toifl S,Farlik M,Halbritter F,Scheicher R,Fischer I,Sexl V,Bock C,Baccarini M

    更新日期：2018-06-01 00:00:00

  • iPSCs to the rescue in Alzheimer's research.

    abstract：:A crucial limitation to our understanding of Alzheimer's disease has been the inability to test hypotheses on live, patient-specific neurons. A recent study in Nature by Israel et al. (2012) reports that iPSC-derived neurons from AD patients recapitulate multiple aspects of disease pathology. ...

    journal_title：Cell stem cell

    pub_type： 评论,杂志文章

    doi：10.1016/j.stem.2012.02.011

    authors： Choi SH,Tanzi RE

    更新日期：2012-03-02 00:00:00

  • Blood cells need glia, too: a new role for the nervous system in the bone marrow niche.

    abstract：:Regulation of hematopoietic stem cell (HSC) dormancy by specific cell types in the hematopoietic niche remains poorly understood. Yamazaki et al. (2011) now report that nerve-associated nonmyelinating Schwann cells activate TGF-β to maintain dormant HSCs, suggesting that glia are novel players in the bone marrow niche...

    journal_title：Cell stem cell

    pub_type： 评论,杂志文章

    doi：10.1016/j.stem.2011.11.016

    authors： Brückner K

    更新日期：2011-12-02 00:00:00

  • Sowing the Seeds of Clonal Hematopoiesis.

    abstract：:As humans age, hematopoietic stem cells (HSCs) occasionally acquire mutations in genes including DNMT3A that enable them to outcompete other HSCs and increase leukemia risk. In this issue of Cell Stem Cell, Tovy et al. (2020) report a previously uncharacterized mechanism by which DNMT3A loss confers increased fitness ...

    journal_title：Cell stem cell

    pub_type： 杂志文章

    doi：10.1016/j.stem.2020.07.011

    authors： Liggett LA,Voit RA,Sankaran VG

    更新日期：2020-08-06 00:00:00

  • Won't You Be My Neighbor? Muscle Stem Cells Recruit Endothelial Cells to Their Niche.

    abstract：:The maintenance of a pool of quiescent satellite cells (muscle stem cells) is necessary for long-term muscle health. In this issue of Cell Stem Cell, Verma et al. (2018) show that satellite cells recruit endothelial cells to create a vascular niche and that cross-talk between endothelial and satellite cells is vital f...

    journal_title：Cell stem cell

    pub_type： 评论,杂志文章

    doi：10.1016/j.stem.2018.09.013

    authors： Collins BC,Kardon G

    更新日期：2018-10-04 00:00:00

  • Generation of rejuvenated antigen-specific T cells by reprogramming to pluripotency and redifferentiation.

    abstract：:Adoptive immunotherapy with functional T cells is potentially an effective therapeutic strategy for combating many types of cancer and viral infection. However, exhaustion of antigen-specific T cells represents a major challenge to this type of approach. In an effort to overcome this problem, we reprogrammed clonally ...

    journal_title：Cell stem cell

    pub_type： 杂志文章

    doi：10.1016/j.stem.2012.11.002

    authors： Nishimura T,Kaneko S,Kawana-Tachikawa A,Tajima Y,Goto H,Zhu D,Nakayama-Hosoya K,Iriguchi S,Uemura Y,Shimizu T,Takayama N,Yamada D,Nishimura K,Ohtaka M,Watanabe N,Takahashi S,Iwamoto A,Koseki H,Nakanishi M,Eto K,Na

    更新日期：2013-01-03 00:00:00

  • A Metformin-Responsive Metabolic Pathway Controls Distinct Steps in Gastric Progenitor Fate Decisions and Maturation.

    abstract：:Cellular metabolism plays important functions in dictating stem cell behaviors, although its role in stomach epithelial homeostasis has not been evaluated in depth. Here, we show that the energy sensor AMP kinase (AMPK) governs gastric epithelial progenitor differentiation. Administering the AMPK activator metformin d...

    journal_title：Cell stem cell

    pub_type： 杂志文章

    doi：10.1016/j.stem.2020.03.006

    authors： Miao ZF,Adkins-Threats M,Burclaff JR,Osaki LH,Sun JX,Kefalov Y,He Z,Wang ZN,Mills JC

    更新日期：2020-06-04 00:00:00

  • Prospective Isolation of Poised iPSC Intermediates Reveals Principles of Cellular Reprogramming.

    abstract：:Cellular reprogramming converts differentiated cells into induced pluripotent stem cells (iPSCs). However, this process is typically very inefficient, complicating mechanistic studies. We identified and molecularly characterized rare, early intermediates poised to reprogram with up to 95% efficiency, without perturbin...

    journal_title：Cell stem cell

    pub_type： 杂志文章

    doi：10.1016/j.stem.2018.06.013

    authors： Schwarz BA,Cetinbas M,Clement K,Walsh RM,Cheloufi S,Gu H,Langkabel J,Kamiya A,Schorle H,Meissner A,Sadreyev RI,Hochedlinger K

    更新日期：2018-08-02 00:00:00

  • The race for regeneration: Pluripotent-stem-cell-derived 3D kidney structures.

    abstract：:The kidney's complex spatial organization and poorly defined lineage specification programs have impeded derivation of kidney progenitors from pluripotent stem cells (PSCs). Now in Cell Stem Cell, Taguchi et al. (2014) redefine the identity of embryonic kidney progenitors in vivo to obtain PSC-derived kidney progenito...

    journal_title：Cell stem cell

    pub_type： 评论,杂志文章

    doi：10.1016/j.stem.2013.12.004

    authors： Gouon-Evans V

    更新日期：2014-01-02 00:00:00

  • Adult neural stem cells bridge their niche.

    abstract：:Major developments in the neural stem cell (NSC) field in recent years provide new insights into the nature of the NSC niche. In this perspective, we integrate recent anatomical data on the organization of the two main neurogenic niches in the adult brain, the ventricular-subventricular zone (V-SVZ) and the subgranula...

    journal_title：Cell stem cell

    pub_type： 杂志文章

    doi：10.1016/j.stem.2012.05.012

    authors： Fuentealba LC,Obernier K,Alvarez-Buylla A

    更新日期：2012-06-14 00:00:00

  • From Skin to Brain: A Parkinson's Disease Patient Transplanted with His Own Cells.

    abstract：:In a pioneering study in New England Journal of Medicine, Schweitzer et al. (2020) report on a patient with Parkinson's disease who received a graft of dopamine neurons obtained from in vitro differentiated induced pluripotent stem cells, derived from the patient's own skin fibroblasts, showing the feasibility of auto...

    journal_title：Cell stem cell

    pub_type： 杂志文章

    doi：10.1016/j.stem.2020.06.008

    authors： Parmar M,Björklund A

    更新日期：2020-07-02 00:00:00

  • Glioblastoma Cancer Stem Cells Evade Innate Immune Suppression of Self-Renewal through Reduced TLR4 Expression.

    abstract：:Tumors contain hostile inflammatory signals generated by aberrant proliferation, necrosis, and hypoxia. These signals are sensed and acted upon acutely by the Toll-like receptors (TLRs) to halt proliferation and activate an immune response. Despite the presence of TLR ligands within the microenvironment, tumors progre...

    journal_title：Cell stem cell

    pub_type： 杂志文章

    doi：10.1016/j.stem.2016.12.001

    authors： Alvarado AG,Thiagarajan PS,Mulkearns-Hubert EE,Silver DJ,Hale JS,Alban TJ,Turaga SM,Jarrar A,Reizes O,Longworth MS,Vogelbaum MA,Lathia JD

    更新日期：2017-04-06 00:00:00

  • The hair follicle bulge stem cell niche resists transformation by the hedgehog pathway.

    abstract：:Similarities between basal cell carcinoma (BCC) tumor cells and hair follicle keratinocytes had previously suggested that BCC originates within the hair follicle bulge stem cell niche. However, in the current Nature Cell Biology, Youssef et al. (2010) show that BCC instead originates in the interfollicular epidermis. ...

    journal_title：Cell stem cell

    pub_type： 评论,杂志文章

    doi：10.1016/j.stem.2010.03.009

    authors： Ridky TW,Khavari PA

    更新日期：2010-04-02 00:00:00

  • Evaluation of Stuart et al.: Distinct Molecular Trajectories Converge to Induce Naive Pluripotency.

    abstract：:An example of the peer review process for "Distinct molecular trajectories converge to induce naive pluripotency" (Stuart et al., 2019) is presented here. ...

    journal_title：Cell stem cell

    pub_type： 评论,杂志文章

    doi：10.1016/j.stem.2019.08.009

    authors： Stadtfeld M

    更新日期：2019-09-05 00:00:00

  • Stem cells by the sea.

    abstract：:The 2009 ISSCR Annual Meeting in Barcelona will draw stem cell scientists from around the world to Europe, to connect to each other and to the local community. With record abstract submissions, we are sure to have an exciting meeting. ...

    journal_title：Cell stem cell

    pub_type： 杂志文章

    doi：10.1016/j.stem.2009.05.009

    authors： McKay RD

    更新日期：2009-06-05 00:00:00

  • De Novo DNA Methylation: Marking the Path from Stem Cell to Neural Fate.

    abstract：:DNA methylation is an epigenetic mark that plays pivotal roles in gene regulation, but its functions in neural fate decisions are poorly understood. In this issue of Cell Stem Cell, Ziller et al. (2018) show that the de novo methyltransferase Dnmt3a ensures efficient generation of motor neurons from stem cells. ...

    journal_title：Cell stem cell

    pub_type： 评论,杂志文章

    doi：10.1016/j.stem.2018.03.006

    authors： Sawai A,Dasen JS

    更新日期：2018-04-05 00:00:00

  • CIRM Alpha Stem Cell Clinics: Collaboratively Addressing Regenerative Medicine Challenges.

    abstract：:The California Institute for Regenerative Medicine (CIRM) Alpha Stem Cell Clinic (ASCC) Network was launched in 2015 to address a compelling unmet medical need for rigorous, FDA-regulated, stem cell-related clinical trials for patients with challenging, incurable diseases. Here, we describe our multi-center experience...

    journal_title：Cell stem cell

    pub_type： 杂志文章

    doi：10.1016/j.stem.2018.05.007

    authors： Jamieson CHM,Millan MT,Creasey AA,Lomax G,Donohoe ME,Walters MC,Abedi M,Bota DA,Zaia JA,Adams JS

    更新日期：2018-06-01 00:00:00

  • The emergence of hematopoietic stem cells is initiated in the placental vasculature in the absence of circulation.

    abstract：:The mouse placenta was unveiled as an important reservoir for hematopoietic stem cells (HSCs), yet the origin of placental HSCs was unknown. By tracking developing HSCs by expression of Runx1-lacZ and CD41, we have found that HSCs emerge in large vessels in the placenta. Analysis of Ncx1(-/-) embryos, which lack a hea...

    journal_title：Cell stem cell

    pub_type： 杂志文章

    doi：10.1016/j.stem.2008.01.001

    authors： Rhodes KE,Gekas C,Wang Y,Lux CT,Francis CS,Chan DN,Conway S,Orkin SH,Yoder MC,Mikkola HK

    更新日期：2008-03-06 00:00:00

  • Single-Cell Transcriptomic Analyses of Cell Fate Transitions during Human Cardiac Reprogramming.

    abstract：:Direct cellular reprogramming provides a powerful platform to study cell plasticity and dissect mechanisms underlying cell fate determination. Here, we report a single-cell transcriptomic study of human cardiac (hiCM) reprogramming that utilizes an analysis pipeline incorporating current data normalization methods, mu...

    journal_title：Cell stem cell

    pub_type： 杂志文章

    doi：10.1016/j.stem.2019.05.020

    authors： Zhou Y,Liu Z,Welch JD,Gao X,Wang L,Garbutt T,Keepers B,Ma H,Prins JF,Shen W,Liu J,Qian L

    更新日期：2019-07-03 00:00:00

  • A scientist's view of the ethics of human embryonic stem cell research.

    abstract：:Scientists are rarely immoral and seldom even amoral. The ethical principles that underlie much of their own work are shared with scientists in other countries to a much greater degree than the cultural and religious differences among those countries would lead one to expect. Like me, few will have had any formal trai...

    journal_title：Cell stem cell

    pub_type： 杂志文章

    doi：10.1016/j.stem.2007.05.003

    authors： McLaren A

    更新日期：2007-06-07 00:00:00

  • Ground State Conditions Induce Rapid Reorganization of Core Pluripotency Factor Binding before Global Epigenetic Reprogramming.

    abstract：:Mouse embryonic stem cells (mESCs) cultured under serum/LIF conditions exhibit heterogeneous expression of pluripotency-associated factors that can be overcome by two inhibitors (2i) of the MEK and GSK3 pathways. Several studies have shown that the "ground state" induced by 2i is characterized by global hypomethylatio...

    journal_title：Cell stem cell

    pub_type： 杂志文章

    doi：10.1016/j.stem.2015.07.005

    authors： Galonska C,Ziller MJ,Karnik R,Meissner A

    更新日期：2015-10-01 00:00:00

  • Lgr5(+ve) stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro.

    abstract：:The study of gastric epithelial homeostasis and cancer has been hampered by the lack of stem cell markers and in vitro culture methods. The Wnt target gene Lgr5 marks stem cells in the small intestine, colon, and hair follicle. Here, we investigated Lgr5 expression in the stomach and assessed the stem cell potential o...

    journal_title：Cell stem cell

    pub_type： 杂志文章

    doi：10.1016/j.stem.2009.11.013

    authors： Barker N,Huch M,Kujala P,van de Wetering M,Snippert HJ,van Es JH,Sato T,Stange DE,Begthel H,van den Born M,Danenberg E,van den Brink S,Korving J,Abo A,Peters PJ,Wright N,Poulsom R,Clevers H

    更新日期：2010-01-08 00:00:00

  • Spatially Restricted Stromal Wnt Signaling Restrains Prostate Epithelial Progenitor Growth through Direct and Indirect Mechanisms.

    abstract：:Cell-autonomous Wnt signaling has well-characterized functions in controlling stem cell activity, including in the prostate. While niche cells secrete Wnt ligands, the effects of Wnt signaling in niche cells per se are less understood. Here, we show that stromal cells in the proximal prostatic duct near the urethra, a...

    journal_title：Cell stem cell

    pub_type： 杂志文章

    doi：10.1016/j.stem.2019.03.010

    authors： Wei X,Zhang L,Zhou Z,Kwon OJ,Zhang Y,Nguyen H,Dumpit R,True L,Nelson P,Dong B,Xue W,Birchmeier W,Taketo MM,Xu F,Creighton CJ,Ittmann MM,Xin L

    更新日期：2019-05-02 00:00:00

  • A Comprehensive Human Gastric Cancer Organoid Biobank Captures Tumor Subtype Heterogeneity and Enables Therapeutic Screening.

    abstract：:Gastric cancer displays marked molecular heterogeneity with aggressive behavior and treatment resistance. Therefore, good in vitro models that encompass unique subtypes are urgently needed for precision medicine development. Here, we have established a primary gastric cancer organoid (GCO) biobank that comprises norma...

    journal_title：Cell stem cell

    pub_type： 杂志文章

    doi：10.1016/j.stem.2018.09.016

    authors： Yan HHN,Siu HC,Law S,Ho SL,Yue SSK,Tsui WY,Chan D,Chan AS,Ma S,Lam KO,Bartfeld S,Man AHY,Lee BCH,Chan ASY,Wong JWH,Cheng PSW,Chan AKW,Zhang J,Shi J,Fan X,Kwong DLW,Mak TW,Yuen ST,Clevers H,Leung SY

    更新日期：2018-12-06 00:00:00

  • A small molecule screen in stem-cell-derived motor neurons identifies a kinase inhibitor as a candidate therapeutic for ALS.

    abstract：:Amyotrophic lateral sclerosis (ALS) is a rapidly progressing neurodegenerative disease, characterized by motor neuron (MN) death, for which there are no truly effective treatments. Here, we describe a new small molecule survival screen carried out using MNs from both wild-type and mutant SOD1 mouse embryonic stem cell...

    journal_title：Cell stem cell

    pub_type： 杂志文章

    doi：10.1016/j.stem.2013.04.003

    authors： Yang YM,Gupta SK,Kim KJ,Powers BE,Cerqueira A,Wainger BJ,Ngo HD,Rosowski KA,Schein PA,Ackeifi CA,Arvanites AC,Davidow LS,Woolf CJ,Rubin LL

    更新日期：2013-06-06 00:00:00