Abstract：
:As humans age, hematopoietic stem cells (HSCs) occasionally acquire mutations in genes including DNMT3A that enable them to outcompete other HSCs and increase leukemia risk. In this issue of Cell Stem Cell, Tovy et al. (2020) report a previously uncharacterized mechanism by which DNMT3A loss confers increased fitness to HSCs by analyzing a rare experiment of nature.
journal_name
Cell Stem Celljournal_title
Cell stem cellauthors
Liggett LA,Voit RA,Sankaran VGdoi
10.1016/j.stem.2020.07.011subject
Has Abstractpub_date
2020-08-06 00:00:00pages
195-197issue
2eissn
1934-5909issn
1875-9777pii
S1934-5909(20)30349-0journal_volume
27pub_type
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