Reprogramming can be a transforming experience.

Abstract:

:Since the inception of nuclear reprogramming, the parallels between this process and tumorigenesis have become increasingly apparent. Recent studies by Abad et al. and Ohnishi et al. have now formalized this connection by demonstrating that the same transcription factors used for reprogramming to pluripotency drive tumor initiation in vivo.

journal_name

Cell Stem Cell

journal_title

Cell stem cell

authors

Hobbs RM,Polo JM

doi

10.1016/j.stem.2014.02.003

subject

Has Abstract

pub_date

2014-03-06 00:00:00

pages

269-71

issue

3

eissn

1934-5909

issn

1875-9777

pii

S1934-5909(14)00054-X

journal_volume

14

pub_type

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