In epigenetic therapy, less is more.

Abstract:

:How DNA methylation inhibitors exert their anticancer effects in patients is not well understood. In the latest issue of Cancer Cell, Tsai et al. (2012) use low-dose drug treatment to induce persistent attenuation of tumorigenicity by targeting tumor-initiating cells.

journal_name

Cell Stem Cell

journal_title

Cell stem cell

authors

Shen H,Laird PW

doi

10.1016/j.stem.2012.03.012

subject

Has Abstract

pub_date

2012-04-06 00:00:00

pages

353-4

issue

4

eissn

1934-5909

issn

1875-9777

pii

S1934-5909(12)00129-4

journal_volume

10

pub_type

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