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Eliminating Cancer Stem Cells in CML with Combination Transcriptional Therapy.

Abstract：

:Leukemia stem cells (LSCs) are resistant to current therapies used to treat chronic myeloid leukemia (CML). Abraham et al. (2016) have identified a molecular network critical for CML LSC survival and propose that simultaneously targeting two of their major transcriptional regulators, p53 and c-Myc, may facilitate their eradication.

journal_name

Cell Stem Cell

journal_title

Cell stem cell

authors

Carvajal LA,Steidl U

doi

10.1016/j.stem.2016.06.005

subject

Has Abstract

pub_date

2016-07-07 00:00:00

pages

6-8

issue

1

eissn

1934-5909

issn

1875-9777

pii

S1934-5909(16)30155-2

journal_volume

19

pub_type

评论,杂志文章

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