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Pluripotency on Lockdown after Deletion of Three Transcription Regulators.

Abstract：

:Exit from the naive pluripotent state occurs through a series of changes in the gene regulatory circuitry, allowing cells to become primed for lineage commitment. In this issue of Cell Stem Cell, Kalkan et al. (2019) show that three transcription regulators are required for naive mouse embryonic stem cells (ESCs) to exit the pluripotent state.

journal_name

Cell Stem Cell

journal_title

Cell stem cell

authors

Mitchell JA

doi

10.1016/j.stem.2019.04.008

subject

Has Abstract

pub_date

2019-05-02 00:00:00

pages

681-683

issue

5

eissn

1934-5909

issn

1875-9777

pii

S1934-5909(19)30157-2

journal_volume

24

pub_type

评论,杂志文章

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