De Novo DNA Methylation: Marking the Path from Stem Cell to Neural Fate.

Abstract:

:DNA methylation is an epigenetic mark that plays pivotal roles in gene regulation, but its functions in neural fate decisions are poorly understood. In this issue of Cell Stem Cell, Ziller et al. (2018) show that the de novo methyltransferase Dnmt3a ensures efficient generation of motor neurons from stem cells.

journal_name

Cell Stem Cell

journal_title

Cell stem cell

authors

Sawai A,Dasen JS

doi

10.1016/j.stem.2018.03.006

subject

Has Abstract

pub_date

2018-04-05 00:00:00

pages

469-471

issue

4

eissn

1934-5909

issn

1875-9777

pii

S1934-5909(18)30112-7

journal_volume

22

pub_type

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