A MEMS-based flexible multichannel ECoG-electrode array.

abstract：OBJECTIVE:We aim to increase the number of neural spikes that can be detected in a single channel extracellular neural recording. APPROACH:We propose a pre-emphasis method facilitating stochastic resonance (SR), where we introduce the band-pass-filtered noisy extracellular recording to an overdamped Brownian particle ...

journal_title：Journal of neural engineering

authors： Güngör CB,Töreyin H

更新日期：2020-09-18 00:00:00

abstract：OBJECTIVE:A primary control signal in brain-computer interfaces (BCIs) have been cortical signals related to movement. However, in cases where natural motor function remains, BCI control signals may interfere with other possibly simultaneous activity for useful ongoing movement. We sought to determine if the brain coul...

journal_title：Journal of neural engineering

authors： Bashford L,Wu J,Sarma D,Collins K,Rao RPN,Ojemann JG,Mehring C

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVE:Multimodal neuroimaging approaches are beneficial to discover brain functionalities at high spatial and temporal resolution. In our work, a novel material composition of a microECoG device relying on Parylene HT and indium-tin-oxide (ITO) is presented, which facilitates two-photon imaging of Ca2+ signals and ...

journal_title：Journal of neural engineering

authors： Zátonyi A,Madarász M,Szabó Á,Lőrincz T,Hodován R,Rózsa B,Fekete Z

更新日期：2020-02-18 00:00:00

abstract：OBJECTIVE:While the positive correlation between impedance and noise of microelectrodes is well known, their quantitative relationship is too rarely described. Knowledge of this relationship provides useful information for both microsystems engineers and electrophysiologists. APPROACH:We discuss the physical basis of ...

journal_title：Journal of neural engineering

authors： Mierzejewski M,Steins H,Kshirsagar P,Jones PD

更新日期：2020-10-15 00:00:00

abstract：OBJECTIVE:Medical implants made of non-biological materials provoke a chronic inflammatory response, resulting in the deposition of a collagenous scar tissue (ST) layer on their surface, that gradually thickens over time. This is a critical problem for neural interfaces. Scar build-up on electrodes results in a progres...

journal_title：Journal of neural engineering

authors： FitzGerald JJ

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVE:Implantable retinal prostheses aim to provide artificial vision to those suffering from retinal degenerative diseases by electrically stimulating the remaining retinal neurons using a multi-electrode array. The spatial resolution of these devices can be improved by creation of so-called virtual channels (VCs)...

journal_title：Journal of neural engineering

authors： Song X,Guo T,Shivdasani MN,Dokos S,Lovell NH,Li X,Qiu S,Li T,Zheng S,Li L

更新日期：2020-10-21 00:00:00

abstract：OBJECTIVE:Analyzing and interpreting the activity of a heterogeneous population of neurons can be challenging, especially as the number of neurons, experimental trials, and experimental conditions increases. One approach is to extract a set of latent variables that succinctly captures the prominent co-fluctuation patte...

journal_title：Journal of neural engineering

authors： Cowley BR,Kaufman MT,Butler ZS,Churchland MM,Ryu SI,Shenoy KV,Yu BM

更新日期：2013-12-01 00:00:00

abstract：OBJECTIVE:Electrocorticography (ECoG) based studies generally analyze features from specific frequency bands selected by manual evaluation of spectral power. However, the definition of these features can vary across subjects, cortical areas, tasks and across time for a given subject. We propose an autoencoder based app...

journal_title：Journal of neural engineering

authors： Pailla T,Miller KJ,Gilja V

更新日期：2019-02-01 00:00:00

abstract：:Adaptive model theory (AMT) is a computational theory that addresses the difficult control problem posed by the musculoskeletal system in interaction with the environment. It proposes that the nervous system creates motor maps and task-dependent synergies to solve the problems of redundancy and limited central resourc...

journal_title：Journal of neural engineering

authors： Neilson PD,Neilson MD

更新日期：2005-09-01 00:00:00

abstract：OBJECTIVE:Due to their increased proximity to retinal ganglion cells (RGCs), epiretinal visual prostheses present the opportunity for eliciting phosphenes with low thresholds through direct RGC activation. This study characterised the in vivo performance of a novel prototype monolithic epiretinal prosthesis, containing...

journal_title：Journal of neural engineering

authors： Shivdasani MN,Evans M,Burns O,Yeoh J,Allen PJ,Nayagam DAX,Villalobos J,Abbott CJ,Luu CD,Opie NL,Sabu A,Saunders AL,McPhedran M,Cardamone L,McGowan C,Maxim V,Williams RA,Fox KE,Cicione R,Garrett DJ,Ahnood A,Ganes

更新日期：2020-08-05 00:00:00

abstract：OBJECTIVE:Visual prostheses are designed to restore partial functional vision in patients with total vision loss. Retinal visual prostheses provide limited capabilities as a result of low resolution, limited field of view and poor dynamic range. Understanding the influence of these parameters in the perception results ...

journal_title：Journal of neural engineering

authors： Sanchez-Garcia M,Martinez-Cantin R,Bermudez-Cameo J,Guerrero JJ

更新日期：2020-10-08 00:00:00

abstract：:The P300 speller is an example of a brain-computer interface that can restore functionality to victims of neuromuscular disorders. Although the most common application of this system has been communicating language, the properties and constraints of the linguistic domain have not to date been exploited when decoding b...

journal_title：Journal of neural engineering

authors： Speier W,Arnold C,Lu J,Taira RK,Pouratian N

更新日期：2012-02-01 00:00:00

abstract：:We investigated the relationships of the firing rate and maximal recruitment threshold of motoneurons recorded during isometric contraction with the number of spindles in individual muscles. At force levels above 10% of maximal voluntary contraction, the firing rate was inversely related to the number of spindles in a...

journal_title：Journal of neural engineering

authors： De Luca CJ,Kline JC

更新日期：2012-02-01 00:00:00

abstract：:All of the human prosthetic visual systems implanted so far have been achromatic. Schmidt et al. (1996) reported that at low stimulation intensities their subject reported that phosphenes usually had a specific hue, but when the stimulus intensity was increased, they desaturated to white. We speculate here that previo...

journal_title：Journal of neural engineering

authors： Towle V,Pham T,McCaffrey M,Allen D,Troyk PR

更新日期：2020-12-18 00:00:00

abstract：OBJECTIVE:Neural reflexes regulate immune responses and homeostasis. Advances in bioelectronic medicine indicate that electrical stimulation of the vagus nerve can be used to treat inflammatory disease, yet the understanding of neural signals that regulate inflammation is incomplete. Current interfaces with the vagus n...

journal_title：Journal of neural engineering

authors： Caravaca AS,Tsaava T,Goldman L,Silverman H,Riggott G,Chavan SS,Bouton C,Tracey KJ,Desimone R,Boyden ES,Sohal HS,Olofsson PS

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVE:When designing multiclass motor imagery-based brain-computer interface (MI-BCI), a so-called tangent space mapping (TSM) method utilizing the geometric structure of covariance matrices is an effective technique. This paper aims to introduce a method using TSM for finding accurate operational frequency bands r...

journal_title：Journal of neural engineering

authors： Islam MR,Tanaka T,Molla MKI

更新日期：2018-08-01 00:00:00

abstract：:Hybrid electro-optical neural stimulation is a novel paradigm combining the advantages of optical and electrical stimulation techniques while reducing their respective limitations. However, in order to fulfill its promise, this technique requires reduced variability and improved reproducibility. Here we used a compara...

journal_title：Journal of neural engineering

authors： Duke AR,Lu H,Jenkins MW,Chiel HJ,Jansen ED

更新日期：2012-06-01 00:00:00

abstract：:In this paper, we propose a simple and straightforward algorithm for neural spike sorting. The algorithm is based on the observation that the distribution of a neural signal largely deviates from the uniform distribution and is rather unimodal. The detected spikes to be sorted are first processed with some feature ext...

journal_title：Journal of neural engineering

authors： Tiganj Z,Mboup M

更新日期：2011-12-01 00:00:00

abstract：OBJECTIVE:In a previous study we demonstrated continuous translation, orientation and one-dimensional grasping control of a prosthetic limb (seven degrees of freedom) by a human subject with tetraplegia using a brain-machine interface (BMI). The current study, in the same subject, immediately followed the previous work...

journal_title：Journal of neural engineering

authors： Wodlinger B,Downey JE,Tyler-Kabara EC,Schwartz AB,Boninger ML,Collinger JL

更新日期：2015-02-01 00:00:00

abstract：:Neural models are increasingly being used as design components of physical systems. In order to best use models in these novel contexts, we must develop design rules that describe how decisions in model construction relate to the functional performance of the resulting system. In the accompanying paper, we described a...

journal_title：Journal of neural engineering

authors： Sorensen ME,DeWeerth SP

更新日期：2007-09-01 00:00:00

abstract：:The functional effects of selective hypoglossal nerve (HG) stimulation with a multi-contact peripheral nerve electrode were assessed using images of the upper airways and the tongue in anesthetized beagles. A biphasic pulse train of 50 Hz frequency and 2 s duration was applied through each one of the tripolar contact ...

journal_title：Journal of neural engineering

authors： Huang J,Sahin M,Durand DM

更新日期：2005-12-01 00:00:00

abstract：:We present the results of a 5-year patient follow-up after implantation of an original neuroprosthesis. The system is able to stimulate both epimysial and neural electrodes in such a way that the complete flexor-extensor chain of the lower limb can be activated without using the withdrawal reflex. We demonstrate that ...

journal_title：Journal of neural engineering

authors： Guiraud D,Stieglitz T,Koch KP,Divoux JL,Rabischong P

更新日期：2006-12-01 00:00:00

abstract：:After extended implantation times, traditional intracortical neural probes exhibit a foreign-body reaction characterized by a reactive glial sheath that has been associated with increased system impedance and signal deterioration. Previously, we have proposed that the local in vivo polymerization of an electronically ...

journal_title：Journal of neural engineering

authors： Ouyang L,Shaw CL,Kuo CC,Griffin AL,Martin DC

更新日期：2014-04-01 00:00:00

abstract：:Repositioning microelectrodes post-implantation is emerging as a promising approach to achieve long-term reliability in single neuronal recordings. The main goal of this study was to (a) assess glial reaction in response to movement of microelectrodes in the brain post-implantation and (b) determine an optimal window ...

journal_title：Journal of neural engineering

authors： Stice P,Muthuswamy J

更新日期：2009-08-01 00:00:00

abstract：:In this work the application of different machine learning techniques for classification of mental tasks from electroencephalograph (EEG) signals is investigated. The main application for this research is the improvement of brain computer interface (BCI) systems. For this purpose, Bayesian graphical network, neural ne...

journal_title：Journal of neural engineering

authors： Rezaei S,Tavakolian K,Nasrabadi AM,Setarehdan SK

更新日期：2006-06-01 00:00:00

abstract：OBJECTIVE:Neuromodulation technologies are increasingly used for improving function after neural injury. To achieve a symbiotic relationship between device and user, the device must augment remaining function, and independently adapt to day-to-day changes in function. The goal of this study was to develop predictive co...

journal_title：Journal of neural engineering

authors： Dalrymple AN,Roszko DA,Sutton RS,Mushahwar VK

更新日期：2020-06-02 00:00:00

abstract：:Alzheimer's disease (AD) is the most common cause of dementia. Over the last few years, a considerable effort has been devoted to exploring new biomarkers. Nevertheless, a better understanding of brain dynamics is still required to optimize therapeutic strategies. In this regard, the characterization of mild cognitive...

journal_title：Journal of neural engineering

authors： Bruña R,Poza J,Gómez C,García M,Fernández A,Hornero R

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVE:Current brain-computer interface (BCI) studies demonstrate the potential to decode neural signals obtained from structured and trial-based tasks to drive actuators with high performance within the context of these tasks. Ideally, to maximize utility, such systems will be applied to a wide range of behavioral ...

journal_title：Journal of neural engineering

authors： Alasfour A,Gabriel P,Jiang X,Shamie I,Melloni L,Thesen T,Dugan P,Friedman D,Doyle W,Devinsky O,Gonda D,Sattar S,Wang S,Halgren E,Gilja V

更新日期：2019-02-01 00:00:00

abstract：OBJECTIVE:Brain-machine interfaces (BMIs) have been proposed in closed-loop applications for neuromodulation and neurorehabilitation. This study describes the impact of different feedback modalities on the performance of an EEG-based BMI that decodes motor imagery (MI) of leg flexion and extension. APPROACH:We execute...

journal_title：Journal of neural engineering

authors： Liu D,Chen W,Lee K,Chavarriaga R,Bouri M,Pei Z,Del R Millán J

更新日期：2017-10-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to compare the use of muscles appropriate for partial-hand prostheses with those typically used for complete hand devices and to determine whether differences in their underlying neural substrates translate to different levels of myoelectric control. APPROACH:We developed a no...

journal_title：Journal of neural engineering

authors： Dyson M,Barnes J,Nazarpour K

更新日期：2018-10-01 00:00:00