The noise and impedance of microelectrodes.

abstract：:Brain-computer interfaces (BCIs) can use brain signals from the scalp (EEG), the cortical surface (ECoG), or within the cortex to restore movement control to people who are paralyzed. Like muscle-based skills, BCIs' use requires activity-dependent adaptations in the brain that maintain stable relationships between the...

journal_title：Journal of neural engineering

authors： McFarland DJ,Sarnacki WA,Wolpaw JR

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:Brain-computer interface (BCI) technology aims to provide individuals with paralysis a means to restore function. Electrocorticography (ECoG) uses disc electrodes placed on either the surface of the dura or the cortex to record field potential activity. ECoG has been proposed as a viable neural recording moda...

journal_title：Journal of neural engineering

authors： Degenhart AD,Hiremath SV,Yang Y,Foldes S,Collinger JL,Boninger M,Tyler-Kabara EC,Wang W

更新日期：2018-04-01 00:00:00

abstract：OBJECTIVE:Spike detection from extracellular recordings is a crucial preprocessing step when analyzing neuronal activity. The decision whether a specific part of the signal is a spike or not is important for any kind of other subsequent preprocessing steps, like spike sorting or burst detection in order to reduce the c...

journal_title：Journal of neural engineering

authors： Lieb F,Stark HG,Thielemann C

更新日期：2017-06-01 00:00:00

abstract：:This paper describes the technological developments underlying the realization of a reliable and reproducible microchip-based stimulator with a large number of stimulus electrodes. A microchip-based stimulator with over 500 electrodes for suprachoroidal transretinal stimulation (STS) is proposed in this paper, and an ...

journal_title：Journal of neural engineering

authors： Ohta J,Tokuda T,Kagawa K,Sugitani S,Taniyama M,Uehara A,Terasawa Y,Nakauchi K,Fujikado T,Tano Y

更新日期：2007-03-01 00:00:00

abstract：OBJECTIVE:High-rate pulse trains have proven to be effective in cochlear prosthetics and, more recently, have been shown to elicit a wide range of interesting response properties in axons of the peripheral nervous system. Surprisingly, the effectiveness of such trains for use in retinal prostheses has not been explored...

journal_title：Journal of neural engineering

authors： Cai C,Twyford P,Fried S

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVE:Penetrating cortical neural probe technologies allow investigators to record electrical signals in the brain. Implantation of probes results in acute tissue damage, and microglia density increases around implanted devices over weeks. However, the mechanisms underlying this encapsulation are not well understoo...

journal_title：Journal of neural engineering

authors： Kozai TD,Vazquez AL,Weaver CL,Kim SG,Cui XT

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVE:Brain-computer interfaces (BCIs) have the potential to be valuable clinical tools. However, the varied nature of BCIs, combined with the large number of laboratories participating in BCI research, makes uniform performance reporting difficult. To address this situation, we present a tutorial on performance me...

journal_title：Journal of neural engineering

authors： Thompson DE,Quitadamo LR,Mainardi L,Laghari KU,Gao S,Kindermans PJ,Simeral JD,Fazel-Rezai R,Matteucci M,Falk TH,Bianchi L,Chestek CA,Huggins JE

更新日期：2014-06-01 00:00:00

abstract：:Automatic spike sorting is a prerequisite for neuroscience research on multichannel extracellular recordings of neuronal activity. A novel spike sorting framework, combining efficient feature extraction and an unsupervised clustering method, is described here. Wavelet transform (WT) is adopted to extract features from...

journal_title：Journal of neural engineering

authors： Lai HY,Chen YY,Lin SH,Lo YC,Tsang S,Chen SY,Zhao WT,Chao WH,Chang YC,Wu R,Shih YY,Tsai ST,Jaw FS

更新日期：2011-06-01 00:00:00

abstract：:We conducted an experiment to determine whether the rhythm with which imagined syllables are produced may be decoded from EEG recordings. High density EEG data were recorded for seven subjects while they produced in imagination one of two syllables in one of three different rhythms. We used a modified second-order bli...

journal_title：Journal of neural engineering

authors： Deng S,Srinivasan R,Lappas T,D'Zmura M

更新日期：2010-08-01 00:00:00

abstract：OBJECTIVE:The various parameters that define a hand movement such as its trajectory, speed, etc, are encoded in distinct brain activities. Decoding this information from neurophysiological recordings is a less explored area of brain-computer interface (BCI) research. Applying non-invasive recordings such as electroence...

journal_title：Journal of neural engineering

authors： Robinson N,Guan C,Vinod AP

更新日期：2015-12-01 00:00:00

abstract：OBJECTIVE:Patients with amyotrophic lateral sclerosis (ALS) may benefit from brain-computer interfaces (BCI), but the utility of such devices likely will have to account for the functional, cognitive, and behavioral heterogeneity of this neurodegenerative disorder. APPROACH:In this study, a heterogeneous group of pati...

journal_title：Journal of neural engineering

authors： Geronimo A,Simmons Z,Schiff SJ

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVE:By means of subjective psychophysical methods, quality of transmitted speech has been decomposed into three perceptual dimensions named 'discontinuity' (F), 'noisiness' (N) and 'coloration' (C). Previous studies using electroencephalography (EEG) already reported effects of perceived intensity of single quali...

journal_title：Journal of neural engineering

authors： Uhrig S,Mittag G,Möller S,Voigt-Antons JN

更新日期：2019-06-01 00:00:00

abstract：:We hypothesize that a visual prosthesis capable of evoking high-resolution visual perceptions can be produced using high-electrode-count arrays of penetrating microelectrodes implanted into the primary visual cortex of a blind human subject. To explore this hypothesis, and as a prelude to human psychophysical experime...

journal_title：Journal of neural engineering

authors： Torab K,Davis TS,Warren DJ,House PA,Normann RA,Greger B

更新日期：2011-06-01 00:00:00

abstract：OBJECTIVE:Neural reflexes regulate immune responses and homeostasis. Advances in bioelectronic medicine indicate that electrical stimulation of the vagus nerve can be used to treat inflammatory disease, yet the understanding of neural signals that regulate inflammation is incomplete. Current interfaces with the vagus n...

journal_title：Journal of neural engineering

authors： Caravaca AS,Tsaava T,Goldman L,Silverman H,Riggott G,Chavan SS,Bouton C,Tracey KJ,Desimone R,Boyden ES,Sohal HS,Olofsson PS

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVE:The reliable estimation of parameters such as mean or covariance matrix from noisy and high-dimensional observations is a prerequisite for successful application of signal processing and machine learning algorithms in brain-computer interfacing (BCI). This challenging task becomes significantly more difficult...

journal_title：Journal of neural engineering

authors： Samek W,Nakajima S,Kawanabe M,Müller KR

更新日期：2017-12-01 00:00:00

abstract：:Microscopic aggregation assay and impedance sensing (IS) were used to monitor a change in in vitro neuron-neuron adhesion in response to blocking of cell adhesion molecules. By blocking neuron-neuron adhesion, migration and aggregation of neuronal cells can be inhibited. This leads to better control of spatial arrange...

journal_title：Journal of neural engineering

authors： Wiertz RW,Marani E,Rutten WL

更新日期：2010-10-01 00:00:00

abstract：:We consider the problem of desynchronizing a network of synchronized, globally (all-to-all) coupled neurons using an input to a single neuron. This is done by applying the discrete time dynamic programming method to reduced phase models for neural populations. This technique numerically minimizes a certain cost functi...

journal_title：Journal of neural engineering

authors： Nabi A,Moehlis J

更新日期：2011-12-01 00:00:00

abstract：OBJECTIVE:Brain-computer interfaces (BCI) are becoming important tools for assistive technology, particularly through the use of motor imagery (MI) for aiding task completion. However, most existing methods of MI classification have been applied in a trial-wise fashion, with window sizes of approximately 2 s or more. A...

journal_title：Journal of neural engineering

authors： Freer D,Yang GZ

更新日期：2020-01-31 00:00:00

abstract：:Deep brain stimulation (DBS) has emerged as an effective treatment for movement disorders; however, the fundamental mechanisms by which DBS works are not well understood. Computational models of DBS can provide insights into these fundamental mechanisms and typically require two steps: calculation of the electrical po...

journal_title：Journal of neural engineering

authors： Zhang TC,Grill WM

更新日期：2010-12-01 00:00:00

abstract：:Repositioning microelectrodes post-implantation is emerging as a promising approach to achieve long-term reliability in single neuronal recordings. The main goal of this study was to (a) assess glial reaction in response to movement of microelectrodes in the brain post-implantation and (b) determine an optimal window ...

journal_title：Journal of neural engineering

authors： Stice P,Muthuswamy J

更新日期：2009-08-01 00:00:00

abstract：:Human trials of prototype visual prostheses have successfully elicited visual percepts (phosphenes) in the visual field of implant recipients blinded through retinitis pigmentosa and age-related macular degeneration. Researchers are progressing rapidly towards a device that utilizes individual phosphenes as the elemen...

journal_title：Journal of neural engineering

authors： Chen SC,Suaning GJ,Morley JW,Lovell NH

更新日期：2009-06-01 00:00:00

abstract：OBJECTIVE:Somatic symptom disorder (SSD) is a reflection of medically unexplained physical symptoms that lead to distress and impairment in social and occupational functioning. SSD is phenomenologically diagnosed and its neurobiology remains unsolved. APPROACH:In this study, we performed hyper-parameter optimized clas...

journal_title：Journal of neural engineering

authors： Eken A,Çolak B,Bal NB,Kuşman A,Kızılpınar SÇ,Akaslan DS,Baskak B

更新日期：2019-12-16 00:00:00

abstract：:Hybrid electro-optical neural stimulation is a novel paradigm combining the advantages of optical and electrical stimulation techniques while reducing their respective limitations. However, in order to fulfill its promise, this technique requires reduced variability and improved reproducibility. Here we used a compara...

journal_title：Journal of neural engineering

authors： Duke AR,Lu H,Jenkins MW,Chiel HJ,Jansen ED

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVE:Most recent steady-state visual evoked potential (SSVEP)-based brain-computer interface (BCI) systems have used a single frequency for each target, so that a large number of targets require a large number of stimulus frequencies and therefore a wider frequency band. However, human beings show good SSVEP respo...

journal_title：Journal of neural engineering

authors： Chen X,Chen Z,Gao S,Gao X

更新日期：2013-12-01 00:00:00

abstract：OBJECTIVE:The use of natural sounds in auditory Brain-Computer Interfaces (BCI) has been shown to improve classification results and usability. Some auditory BCIs are based on stream segregation, in which the subjects must attend one audio stream and ignore the other(s); these streams include some kind of stimuli to be...

journal_title：Journal of neural engineering

authors： Velasco-Álvarez F,Fernández-Rodríguez Á,Medina-Juliá MT,Ron-Angevin R

更新日期：2021-01-19 00:00:00

abstract：OBJECTIVE:Current brain-computer interface (BCI) studies demonstrate the potential to decode neural signals obtained from structured and trial-based tasks to drive actuators with high performance within the context of these tasks. Ideally, to maximize utility, such systems will be applied to a wide range of behavioral ...

journal_title：Journal of neural engineering

authors： Alasfour A,Gabriel P,Jiang X,Shamie I,Melloni L,Thesen T,Dugan P,Friedman D,Doyle W,Devinsky O,Gonda D,Sattar S,Wang S,Halgren E,Gilja V

更新日期：2019-02-01 00:00:00

abstract：:Improving cortical prostheses requires the development of recording neural interfaces that are efficient in terms of providing maximal control information with minimal interface complexity. While the typical approaches have targeted neurons in the motor cortex with multiple penetrating shanks, an alternative approach ...

journal_title：Journal of neural engineering

authors： Parikh H,Marzullo TC,Kipke DR

更新日期：2009-04-01 00:00:00

abstract：:In this work we address the use of realtime cortical recordings for the generation of coherent, reliable and robust motor activity in spinal-lesioned animals through selective intraspinal microstimulation (ISMS). The spinal cord of adult rats was hemisectioned and groups of multielectrodes were implanted in both the c...

journal_title：Journal of neural engineering

authors： Panetsos F,Sanchez-Jimenez A,Torets C,Largo C,Micera S

更新日期：2011-08-01 00:00:00

abstract：:Implantable electrode arrays capable of recording and stimulating neural activity with high spatial and temporal resolution will provide a foundation for future brain computer interface technology. Currently, their clinical impact has been curtailed by a general lack of functional stability, which can be attributed to...

journal_title：Journal of neural engineering

authors： Retterer ST,Smith KL,Bjornsson CS,Turner JN,Isaacson MS,Shain W

更新日期：2008-12-01 00:00:00

abstract：:Spastic hypertonus (muscle over-activity due to exaggerated stretch reflexes) often develops in people with stroke, cerebral palsy, multiple sclerosis and spinal cord injury. Lesioning of nerves, e.g. with phenol or botulinum toxin is widely performed to reduce spastic hypertonus. We have explored the use of direct el...

journal_title：Journal of neural engineering

authors： Ravid EN,Gan LS,Todd K,Prochazka A

更新日期：2011-02-01 00:00:00