A non-parametric method for automatic neural spike clustering based on the non-uniform distribution of the data.

abstract：OBJECTIVE:Damage to the brain, as a result of various medical conditions, impacts the everyday life of patients and there is still no complete cure to neurological disorders. Neuroprostheses that can functionally replace the damaged neural circuit have recently emerged as a possible solution to these problems. Here we ...

journal_title：Journal of neural engineering

authors： Xu T,Xiao N,Zhai X,Kwan Chan P,Tin C

更新日期：2018-02-01 00:00:00

abstract：:Functional electrical stimulation (FES) involves artificial activation of muscles with surface or implanted electrodes to restore motor function in paralyzed individuals. Currently, FES-based prostheses produce only a limited range of movements due to the difficulty associated with identifying patterns of muscle activ...

journal_title：Journal of neural engineering

authors： Johnson LA,Fuglevand AJ

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVE:Advances in electrode technology have facilitated the development of neuroprostheses for restoring motor/sensory function in disabled individuals. Information extracted from a whole nerve, recorded using cuffs, can provide signals that control the operation of neuroprostheses. However, the amount of informati...

journal_title：Journal of neural engineering

authors： Sabetian P,Yoo PB

更新日期：2020-01-28 00:00:00

abstract：OBJECTIVE:Implantable retinal prostheses aim to provide artificial vision to those suffering from retinal degenerative diseases by electrically stimulating the remaining retinal neurons using a multi-electrode array. The spatial resolution of these devices can be improved by creation of so-called virtual channels (VCs)...

journal_title：Journal of neural engineering

authors： Song X,Guo T,Shivdasani MN,Dokos S,Lovell NH,Li X,Qiu S,Li T,Zheng S,Li L

更新日期：2020-10-21 00:00:00

abstract：:Functional mapping of eloquent cortex is a common and necessary component of neurosurgical operative planning. Current electrical stimulation-based techniques are inefficient, can evoke seizures and are prone to false-negative results. Here, we present a novel cortical mapping system that extracts event-related neural...

journal_title：Journal of neural engineering

authors： Cheung C,Chang EF

更新日期：2012-08-01 00:00:00

abstract：OBJECTIVE:Reliable chronic recordings from implanted neural probes remain a significant challenge; current silicon-based and microwire technologies experience a wide range of biotic and abiotic failure modes contributing to loss of signal quality. APPROACH:A multi-prong alternative strategy with potential to overcome ...

journal_title：Journal of neural engineering

authors： Kim BJ,Kuo JT,Hara SA,Lee CD,Yu L,Gutierrez CA,Hoang TQ,Pikov V,Meng E

更新日期：2013-08-01 00:00:00

abstract：OBJECTIVE:Brains, like other physical devices, are inherently noisy. This source of variability is large, to the extent that internal noise often impacts human sensory processing more than externally induced (stimulus-driven) perturbations. Despite the fundamental nature of this phenomenon, its statistical distribution...

journal_title：Journal of neural engineering

authors： Neri P

更新日期：2013-02-01 00:00:00

abstract：OBJECTIVE:Analysis of intra- and perioperatively recorded cortical and basal ganglia local field potentials in human movement disorders has provided great insight into the pathophysiology of diseases such as Parkinson's, dystonia, and essential tremor. However, in order to better understand the network abnormalities an...

journal_title：Journal of neural engineering

authors： Ryapolova-Webb E,Afshar P,Stanslaski S,Denison T,de Hemptinne C,Bankiewicz K,Starr PA

更新日期：2014-02-01 00:00:00

abstract：OBJECTIVE:Patients with amyotrophic lateral sclerosis (ALS) may benefit from brain-computer interfaces (BCI), but the utility of such devices likely will have to account for the functional, cognitive, and behavioral heterogeneity of this neurodegenerative disorder. APPROACH:In this study, a heterogeneous group of pati...

journal_title：Journal of neural engineering

authors： Geronimo A,Simmons Z,Schiff SJ

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVE:We aim to increase the number of neural spikes that can be detected in a single channel extracellular neural recording. APPROACH:We propose a pre-emphasis method facilitating stochastic resonance (SR), where we introduce the band-pass-filtered noisy extracellular recording to an overdamped Brownian particle ...

journal_title：Journal of neural engineering

authors： Güngör CB,Töreyin H

更新日期：2020-09-18 00:00:00

abstract：OBJECTIVE:Research by Oby et al (2016) demonstrated that the optimal threshold for extracting information from visual and motor cortices may differ from the optimal threshold for identifying single neurons via spike sorting methods. The optimal threshold for extracting information from auditory cortex has yet to be ide...

journal_title：Journal of neural engineering

authors： Bigelow J,Malone B

更新日期：2020-03-03 00:00:00

abstract：OBJECTIVE:By means of subjective psychophysical methods, quality of transmitted speech has been decomposed into three perceptual dimensions named 'discontinuity' (F), 'noisiness' (N) and 'coloration' (C). Previous studies using electroencephalography (EEG) already reported effects of perceived intensity of single quali...

journal_title：Journal of neural engineering

authors： Uhrig S,Mittag G,Möller S,Voigt-Antons JN

更新日期：2019-06-01 00:00:00

abstract：OBJECTIVE:Current mapping of epileptic networks in patients prior to epilepsy surgery utilizes electrode arrays with sparse spatial sampling (∼1.0 cm inter-electrode spacing). Recent research demonstrates that sub-millimeter, cortical-column-scale domains have a role in seizure generation that may be clinically signifi...

journal_title：Journal of neural engineering

authors： Vanleer AC,Blanco JA,Wagenaar JB,Viventi J,Contreras D,Litt B

更新日期：2016-04-01 00:00:00

abstract：:We conducted an experiment to determine whether the rhythm with which imagined syllables are produced may be decoded from EEG recordings. High density EEG data were recorded for seven subjects while they produced in imagination one of two syllables in one of three different rhythms. We used a modified second-order bli...

journal_title：Journal of neural engineering

authors： Deng S,Srinivasan R,Lappas T,D'Zmura M

更新日期：2010-08-01 00:00:00

abstract：OBJECTIVE:We propose a new hybrid brain-computer interface (BCI) system that integrates two different EEG tasks: tactile selective attention (TSA) using a vibro-tactile stimulator on the left/right finger and motor imagery (MI) of left/right hand movement. Event-related desynchronization (ERD) from the MI task and stea...

journal_title：Journal of neural engineering

authors： Ahn S,Ahn M,Cho H,Chan Jun S

更新日期：2014-12-01 00:00:00

abstract：:Adaptive model theory (AMT) is a computational theory that addresses the difficult control problem posed by the musculoskeletal system in interaction with the environment. It proposes that the nervous system creates motor maps and task-dependent synergies to solve the problems of redundancy and limited central resourc...

journal_title：Journal of neural engineering

authors： Neilson PD,Neilson MD

更新日期：2005-09-01 00:00:00

abstract：:This review paper shows that tungsten should not generally be used as a chronically implanted material. The metal has a long implant history, from neuroscience, vascular medicine, radiography, orthopaedics, prosthodontics, and various other fields, primarily as a result of its high density, radiopacity, tensile streng...

journal_title：Journal of neural engineering

authors： Shah Idil A,Donaldson N

更新日期：2018-04-01 00:00:00

abstract：:After extended implantation times, traditional intracortical neural probes exhibit a foreign-body reaction characterized by a reactive glial sheath that has been associated with increased system impedance and signal deterioration. Previously, we have proposed that the local in vivo polymerization of an electronically ...

journal_title：Journal of neural engineering

authors： Ouyang L,Shaw CL,Kuo CC,Griffin AL,Martin DC

更新日期：2014-04-01 00:00:00

abstract：:Chronic motor cortex stimulation (MCS) is currently being investigated as a treatment method for Parkinson's disease (PD). Unfortunately, the underlying mechanisms of this treatment are unclear and there are many uncertainties regarding the most effective stimulation parameters and electrode configuration. In this pap...

journal_title：Journal of neural engineering

authors： Zwartjes DG,Heida T,Feirabend HK,Janssen ML,Visser-Vandewalle V,Martens HC,Veltink PH

更新日期：2012-10-01 00:00:00

abstract：OBJECTIVE:Neural modulation is a fundamental tool for understanding and treating neurological and psychiatric diseases. However, due to the high-dimensional space, subject-specific responses, and variability within each subject, it is a major challenge to select the stimulation parameters that have the desired effect. ...

journal_title：Journal of neural engineering

authors： Connolly MJ,Park SE,Laxpati NG,Zaidi SA,Ghetiya M,Fernandez A,Gutekunst CA,Gross RE

更新日期：2020-12-03 00:00:00

abstract：:Improving cortical prostheses requires the development of recording neural interfaces that are efficient in terms of providing maximal control information with minimal interface complexity. While the typical approaches have targeted neurons in the motor cortex with multiple penetrating shanks, an alternative approach ...

journal_title：Journal of neural engineering

authors： Parikh H,Marzullo TC,Kipke DR

更新日期：2009-04-01 00:00:00

abstract：:Corrosion is a prime concern for active implantable devices. In this paper we review the principles underlying the concepts of hermetic packages and encapsulation, used to protect implanted electronics, some of which remain widely overlooked. We discuss how technological advances have created a need to update the way ...

journal_title：Journal of neural engineering

authors： Vanhoestenberghe A,Donaldson N

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVE:Electroencephalography (EEG) recorded during transcranial alternating current simulation (tACS) is highly desirable in order to investigate brain dynamics during stimulation, but is corrupted by large amplitude stimulation artefacts. Artefact removal algorithms have been presented previously, but with substan...

journal_title：Journal of neural engineering

authors： Kohli S,Casson AJ

更新日期：2020-01-24 00:00:00

abstract：:In this paper we propose a dual stream neural network (DSNN) for classifying arbitrary collections of functional neuroimaging signals for the purpose of brain computer interfaces (BCIs). In the DSNN the first stream is an end-to-end classifier taking raw time-dependent signals as input and generating feature identific...

journal_title：Journal of neural engineering

authors： Kuang D,Michoski C

更新日期：2020-11-10 00:00:00

abstract：OBJECTIVE:We presented a comparative study on the training methodologies of a convolutional neural network (CNN) for the detection of steady-state visually evoked potentials (SSVEP). Two training scenarios were also compared: user-independent (UI) training and user-dependent (UD) training. APPROACH:The CNN was trained...

journal_title：Journal of neural engineering

authors： Ravi A,Beni NH,Manuel J,Jiang N

更新日期：2020-04-08 00:00:00

abstract：OBJECTIVE:Intramuscular electromyography (iEMG) signals, non-invasively recorded, directly from the muscles are used to diagnose various neuromuscular disorders/diseases, also to control rehabilitative and assistive robotic devices. iEMG signals are being potentially used in neurology, kinesiology, rehabilitation, and ...

journal_title：Journal of neural engineering

authors： Ashraf H,Waris A,Gilani SO,Kashif AS,Jamil M,Jochumsen M,Niazi IK

更新日期：2020-11-20 00:00:00

abstract：OBJECTIVE:Currently commercially available nerve conduits have demonstrated suboptimal clinical efficacy in repairing peripheral nerve defects. Although tissue-engineered nerve grafts (TENGs) with sustained release of neurotrophic factors (NTFs) are experimentally proved to be more effective than these blank conduits, ...

journal_title：Journal of neural engineering

authors： Liu Y,Yu S,Gu X,Cao R,Cui S

更新日期：2019-06-01 00:00:00

abstract：OBJECTIVE:Given current clinical interest in vagus nerve stimulation (VNS), there are surprisingly few studies characterizing the anatomy of the vagus nerve in large animal models as it pertains to on-and off-target engagement of local fibers. We sought to address this gap by evaluating vagal anatomy in the pig, whose ...

journal_title：Journal of neural engineering

authors： Settell ML,Pelot NA,Knudsen BE,Dingle AM,McConico AL,Nicolai EN,Trevathan JK,Ezzell JA,Ross EK,Gustafson KJ,Shoffstall AJ,Williams JC,Zeng W,Poore SO,Populin LC,Suminski AJ,Grill WM,Ludwig KA

更新日期：2020-04-09 00:00:00

abstract：:Deep brain stimulation (DBS) of the subthalamic nucleus with periodic, high-frequency pulse trains is an increasingly standard therapy for advanced Parkinson's disease. Here, we propose that a closed-loop global optimization algorithm may identify novel DBS waveforms that could be more effective than their high-freque...

journal_title：Journal of neural engineering

authors： Feng XJ,Greenwald B,Rabitz H,Shea-Brown E,Kosut R

更新日期：2007-06-01 00:00:00

abstract：:We introduce algorithms and architectures for automatic spike detection and alignment that are designed for low power. Some of the algorithms are based on principal component analysis (PCA). Others employ a novel integral transform analysis and achieve 99% of the precision of a PCA detector, while requiring only 0.05%...

journal_title：Journal of neural engineering

authors： Zviagintsev A,Perelman Y,Ginosar R

更新日期：2006-03-01 00:00:00