Real-time, time-frequency mapping of event-related cortical activation.

abstract：OBJECTIVE:Cochlear implants, while providing significant benefits to recipients, remain limited due to broad neural activation. Focussed multipolar stimulation (FMP) is an advanced stimulation strategy that uses multiple current sources to produce highly focussed patterns of neural excitation in order to overcome these...

journal_title：Journal of neural engineering

authors： Senn P,Shepherd RK,Fallon JB

更新日期：2018-10-01 00:00:00

abstract：OBJECTIVE:Most brain-computer interfaces (BCIs) based on functional near-infrared spectroscopy (fNIRS) require that users perform mental tasks such as motor imagery, mental arithmetic, or music imagery to convey a message or to answer simple yes or no questions. These cognitive tasks usually have no direct association ...

journal_title：Journal of neural engineering

authors： Rezazadeh Sereshkeh A,Yousefi R,Wong AT,Chau T

更新日期：2019-02-01 00:00:00

abstract：OBJECTIVE:Penetrating cortical neural probe technologies allow investigators to record electrical signals in the brain. Implantation of probes results in acute tissue damage, and microglia density increases around implanted devices over weeks. However, the mechanisms underlying this encapsulation are not well understoo...

journal_title：Journal of neural engineering

authors： Kozai TD,Vazquez AL,Weaver CL,Kim SG,Cui XT

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVE:The vision of bioelectronic medicine is to treat disease by modulating the signaling of visceral nerves near various end organs. In small animal models, the nerves of interest can have small diameters and limited surgical access. New high-resolution methods for building nerve interfaces are desirable. In this...

journal_title：Journal of neural engineering

authors： Lissandrello CA,Gillis WF,Shen J,Pearre BW,Vitale F,Pasquali M,Holinski BJ,Chew DJ,White AE,Gardner TJ

更新日期：2017-06-01 00:00:00

abstract：:Growing neurons navigate complex environments, but in vitro systems for studying neuronal growth typically limit the cues to flat surfaces or a single type of cue, thereby limiting the resulting growth. Here we examined the growth of neurons presented with two-dimensional (2D) substrate-bound cues when these cues were...

journal_title：Journal of neural engineering

authors： Kofron CM,Fong VJ,Hoffman-Kim D

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVE:Analyzing and interpreting the activity of a heterogeneous population of neurons can be challenging, especially as the number of neurons, experimental trials, and experimental conditions increases. One approach is to extract a set of latent variables that succinctly captures the prominent co-fluctuation patte...

journal_title：Journal of neural engineering

authors： Cowley BR,Kaufman MT,Butler ZS,Churchland MM,Ryu SI,Shenoy KV,Yu BM

更新日期：2013-12-01 00:00:00

abstract：OBJECTIVE:Spike detection from extracellular recordings is a crucial preprocessing step when analyzing neuronal activity. The decision whether a specific part of the signal is a spike or not is important for any kind of other subsequent preprocessing steps, like spike sorting or burst detection in order to reduce the c...

journal_title：Journal of neural engineering

authors： Lieb F,Stark HG,Thielemann C

更新日期：2017-06-01 00:00:00

abstract：OBJECTIVE:In a previous study we demonstrated continuous translation, orientation and one-dimensional grasping control of a prosthetic limb (seven degrees of freedom) by a human subject with tetraplegia using a brain-machine interface (BMI). The current study, in the same subject, immediately followed the previous work...

journal_title：Journal of neural engineering

authors： Wodlinger B,Downey JE,Tyler-Kabara EC,Schwartz AB,Boninger ML,Collinger JL

更新日期：2015-02-01 00:00:00

abstract：OBJECTIVE:Stability and selectivity are important when restoring long-term, functional sensory feedback in individuals with limb-loss. Our objective is to demonstrate a chronic, clinical neural stimulation system for providing selective sensory response in two upper-limb amputees. APPROACH:Multi-contact cuff electrode...

journal_title：Journal of neural engineering

authors： Tan DW,Schiefer MA,Keith MW,Anderson JR,Tyler DJ

更新日期：2015-04-01 00:00:00

abstract：OBJECTIVE:Brains, like other physical devices, are inherently noisy. This source of variability is large, to the extent that internal noise often impacts human sensory processing more than externally induced (stimulus-driven) perturbations. Despite the fundamental nature of this phenomenon, its statistical distribution...

journal_title：Journal of neural engineering

authors： Neri P

更新日期：2013-02-01 00:00:00

abstract：OBJECTIVE:Brain-computer interfaces (BCIs) have the potential to be valuable clinical tools. However, the varied nature of BCIs, combined with the large number of laboratories participating in BCI research, makes uniform performance reporting difficult. To address this situation, we present a tutorial on performance me...

journal_title：Journal of neural engineering

authors： Thompson DE,Quitadamo LR,Mainardi L,Laghari KU,Gao S,Kindermans PJ,Simeral JD,Fazel-Rezai R,Matteucci M,Falk TH,Bianchi L,Chestek CA,Huggins JE

更新日期：2014-06-01 00:00:00

abstract：:The gait outcome measures used in clinical trials of paraplegic locomotor training determine the effectiveness of improved walking function assisted by the functional electrical stimulation (FES) system. Focused on kinematic, kinetic or physiological changes of paraplegic patients, traditional methods cannot quantify ...

journal_title：Journal of neural engineering

authors： Ming D,Bai Y,Liu X,Qi H,Cheng L,Wan B,Hu Y,Wong Y,Luk KD,Leong JC

更新日期：2009-12-01 00:00:00

abstract：OBJECTIVE:Current mapping of epileptic networks in patients prior to epilepsy surgery utilizes electrode arrays with sparse spatial sampling (∼1.0 cm inter-electrode spacing). Recent research demonstrates that sub-millimeter, cortical-column-scale domains have a role in seizure generation that may be clinically signifi...

journal_title：Journal of neural engineering

authors： Vanleer AC,Blanco JA,Wagenaar JB,Viventi J,Contreras D,Litt B

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVE:Although electrode size should be miniaturized to provide higher selectivity for neural signal recording and to avoid tissue damage, small sized electrodes induce high impedance, which decreases recording quality. In this work, the electrode surface was modified to increase the effective surface area to lower...

journal_title：Journal of neural engineering

authors： Chung T,Wang JQ,Wang J,Cao B,Li Y,Pang SW

更新日期：2015-10-01 00:00:00

abstract：:This paper describes the technological developments underlying the realization of a reliable and reproducible microchip-based stimulator with a large number of stimulus electrodes. A microchip-based stimulator with over 500 electrodes for suprachoroidal transretinal stimulation (STS) is proposed in this paper, and an ...

journal_title：Journal of neural engineering

authors： Ohta J,Tokuda T,Kagawa K,Sugitani S,Taniyama M,Uehara A,Terasawa Y,Nakauchi K,Fujikado T,Tano Y

更新日期：2007-03-01 00:00:00

abstract：OBJECTIVE:Currently commercially available nerve conduits have demonstrated suboptimal clinical efficacy in repairing peripheral nerve defects. Although tissue-engineered nerve grafts (TENGs) with sustained release of neurotrophic factors (NTFs) are experimentally proved to be more effective than these blank conduits, ...

journal_title：Journal of neural engineering

authors： Liu Y,Yu S,Gu X,Cao R,Cui S

更新日期：2020-12-09 00:00:00

abstract：OBJECTIVE:Analysis of intra- and perioperatively recorded cortical and basal ganglia local field potentials in human movement disorders has provided great insight into the pathophysiology of diseases such as Parkinson's, dystonia, and essential tremor. However, in order to better understand the network abnormalities an...

journal_title：Journal of neural engineering

authors： Ryapolova-Webb E,Afshar P,Stanslaski S,Denison T,de Hemptinne C,Bankiewicz K,Starr PA

更新日期：2014-02-01 00:00:00

abstract：OBJECTIVE:Electroencephalography (EEG) offers a unique opportunity to study human neural activity non-invasively with millisecond resolution using minimal equipment in or outside of a lab setting. EEG can be combined with a number of techniques for closed-loop experiments, where external devices are driven by specific ...

journal_title：Journal of neural engineering

authors： Black C,Voigts J,Agrawal U,Ladow M,Santoyo J,Moore C,Jones S

更新日期：2017-06-01 00:00:00

abstract：OBJECTIVE:The objective of this work is to present gumpy, a new free and open source Python toolbox designed for hybrid brain-computer interface (BCI). APPROACH:Gumpy provides state-of-the-art algorithms and includes a rich selection of signal processing methods that have been employed by the BCI community over the la...

journal_title：Journal of neural engineering

authors： Tayeb Z,Waniek N,Fedjaev J,Ghaboosi N,Rychly L,Widderich C,Richter C,Braun J,Saveriano M,Cheng G,Conradt J

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVE:Despite the high number of degrees of freedom of the human hand, most actions of daily life can be executed incorporating only palmar, pincer and lateral grasp. In this study we attempt to discriminate these three different executed reach-and-grasp actions utilizing their EEG neural correlates. APPROACH:In a...

journal_title：Journal of neural engineering

authors： Schwarz A,Ofner P,Pereira J,Sburlea AI,Müller-Putz GR

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVE:Recording of neural signals from intact peripheral nerves in patients with spinal cord injury or stroke survivors offers the possibility for the development of closed-loop sensorimotor prostheses. Nerve cuffs have been found to provide stable recordings from peripheral nerves for prolonged periods of time. Ho...

journal_title：Journal of neural engineering

authors： Silveira C,Brunton E,Spendiff S,Nazarpour K

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVE:Intracortical brain-machine interfaces (iBMIs) aim to restore efficient communication and movement ability for paralyzed patients. However, frequent recalibration is required for consistency and reliability, and every recalibration will require relatively large most current sample set. The aim in this study i...

journal_title：Journal of neural engineering

authors： Zhang P,Ma X,Chen L,Zhou J,Wang C,Li W,He J

更新日期：2018-04-01 00:00:00

abstract：OBJECTIVE:Haptic perception of a prosthetic limb or hand is a crucial, but often unmet, need which impacts the utility of the prostheses. In this study, we seek to evaluate the feasibility of a non-invasive transcutaneous nerve stimulation method in generating haptic feedback in a transradial amputee subject as well as...

journal_title：Journal of neural engineering

authors： Shin H,Watkins Z,Huang HH,Zhu Y,Hu X

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVE:Multiresolution analysis (MRA) offers a useful framework for signal analysis in the temporal and spectral domains, although commonly employed MRA methods may not be the best approach for brain computer interface (BCI) applications. This study aims to develop a new MRA system for extracting tempo-spatial-spect...

journal_title：Journal of neural engineering

authors： Asensio-Cubero J,Gan JQ,Palaniappan R

更新日期：2013-08-01 00:00:00

abstract：OBJECTIVE:Brain-computer interfaces (BCIs) are confronted with two fundamental challenges: (a) the uncertainty associated with decoding noisy brain signals, and (b) the need for co-adaptation between the brain and the interface so as to cooperatively achieve a common goal in a task. We seek to mitigate these challenges...

journal_title：Journal of neural engineering

authors： Bryan MJ,Martin SA,Cheung W,Rao RP

更新日期：2013-12-01 00:00:00

abstract：OBJECTIVE:To evaluate the benefit of integrating thermal imaging into an artificial vision therapy system, the Argus II retinal prosthesis, in simplifying a complex scene and improving mobility performance in the presence of other persons. APPROACH:Four Argus II retinal implant users were evaluated on two tasks: to lo...

journal_title：Journal of neural engineering

authors： He Y,Sun SY,Roy A,Caspi A,Montezuma SR

更新日期：2020-08-04 00:00:00

abstract：:This comment constitutes a re-assessment of a recent study in which near-infrared spectroscopy (NIRS) was used to decode decision making. In the original study, the process of feature selection was carried out on all of the data, and those features which displayed the greater classification accuracy were selected, but...

journal_title：Journal of neural engineering

authors： Dominguez LG

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVE:Damage to the brain, as a result of various medical conditions, impacts the everyday life of patients and there is still no complete cure to neurological disorders. Neuroprostheses that can functionally replace the damaged neural circuit have recently emerged as a possible solution to these problems. Here we ...

journal_title：Journal of neural engineering

authors： Xu T,Xiao N,Zhai X,Kwan Chan P,Tin C

更新日期：2018-02-01 00:00:00

abstract：:Neural activity can be modulated by applying a polarizing low-frequency (<100 Hz) electric field (PLEF). Unlike conventional pulsed stimulation, PLEF stimulation has a graded, modulatory effect on neuronal excitability, and permits the simultaneous recording of neuronal activity during stimulation suitable for continu...

journal_title：Journal of neural engineering

authors： Sunderam S,Chernyy N,Peixoto N,Mason JP,Weinstein SL,Schiff SJ,Gluckman BJ

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVE:Studies have shown that low frequency components of brain recordings provide information on voluntary hand movement directions. However, non-invasive techniques face more challenges compared to invasive techniques. APPROACH:This study presents a novel signal processing technique to extract features from non-...

journal_title：Journal of neural engineering

authors： Robinson N,Guan C,Vinod AP,Ang KK,Tee KP

更新日期：2013-10-01 00:00:00