Motor cortex stimulation for Parkinson's disease: a modelling study.

abstract：:Retinal implants have proven their ability to restore visual sensation to people with degenerative retinopathy, characterized by photoreceptor cell death and the retina's inability to sense light. Retinal bionics operate by electrically stimulating the surviving neurons in the retina, thus triggering the transfer of v...

journal_title：Journal of neural engineering

authors： Bareket L,Barriga-Rivera A,Zapf MP,Lovell NH,Suaning GJ

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVE:Over the past two decades retinal prostheses have made major strides in restoring functional vision to patients blinded by diseases such as retinitis pigmentosa. Presently, implants use single pulses to activate the retina. Though this stimulation paradigm has proved beneficial to patients, an unresolved prob...

journal_title：Journal of neural engineering

authors： Sekhar S,Jalligampala A,Zrenner E,Rathbun DL

更新日期：2017-08-01 00:00:00

abstract：:We consider the problem of desynchronizing a network of synchronized, globally (all-to-all) coupled neurons using an input to a single neuron. This is done by applying the discrete time dynamic programming method to reduced phase models for neural populations. This technique numerically minimizes a certain cost functi...

journal_title：Journal of neural engineering

authors： Nabi A,Moehlis J

更新日期：2011-12-01 00:00:00

abstract：OBJECTIVE:Wireless control and power harvesting systems that operate injectable, cellular-scale optoelectronic components provide important demonstrated capabilities in neuromodulatory techniques such as optogenetics. Here, we report a radio frequency (RF) control/harvesting device that offers dramatically reduced size...

journal_title：Journal of neural engineering

authors： Park SI,Shin G,Banks A,McCall JG,Siuda ER,Schmidt MJ,Chung HU,Noh KN,Mun JG,Rhodes J,Bruchas MR,Rogers JA

更新日期：2015-10-01 00:00:00

abstract：OBJECTIVE:We aim to increase the number of neural spikes that can be detected in a single channel extracellular neural recording. APPROACH:We propose a pre-emphasis method facilitating stochastic resonance (SR), where we introduce the band-pass-filtered noisy extracellular recording to an overdamped Brownian particle ...

journal_title：Journal of neural engineering

authors： Güngör CB,Töreyin H

更新日期：2020-09-18 00:00:00

abstract：OBJECTIVE:The objective of this work is to present gumpy, a new free and open source Python toolbox designed for hybrid brain-computer interface (BCI). APPROACH:Gumpy provides state-of-the-art algorithms and includes a rich selection of signal processing methods that have been employed by the BCI community over the la...

journal_title：Journal of neural engineering

authors： Tayeb Z,Waniek N,Fedjaev J,Ghaboosi N,Rychly L,Widderich C,Richter C,Braun J,Saveriano M,Cheng G,Conradt J

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVE:Despite the high number of degrees of freedom of the human hand, most actions of daily life can be executed incorporating only palmar, pincer and lateral grasp. In this study we attempt to discriminate these three different executed reach-and-grasp actions utilizing their EEG neural correlates. APPROACH:In a...

journal_title：Journal of neural engineering

authors： Schwarz A,Ofner P,Pereira J,Sburlea AI,Müller-Putz GR

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVE:Many physical models of biological processes including neural systems are characterized by parametric nonlinear dynamical relations between driving inputs, internal states, and measured outputs of the process. Fitting such models using experimental data (data assimilation) is a challenging task since the phys...

journal_title：Journal of neural engineering

authors： Madi MK,Karameh FN

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVE:Given the rapid expansion of the field of neural stimulation and the rigorous regulatory approval requirements required before these devices can be applied clinically, it is important that there is clarity around conducting preclinical safety and efficacy studies required for the development of this technolog...

journal_title：Journal of neural engineering

authors： Shepherd RK,Villalobos J,Burns O,Nayagam DAX

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVE:Assessing an infant's brain development remains a challenge for neuroscientists and pediatricians despite great technological advances. As a non-invasive neuroimaging tool, functional near-infrared spectroscopy (fNIRS) has great advantages in monitoring an infant's brain activity. To explore the dynamic featu...

journal_title：Journal of neural engineering

authors： Liang Z,Minagawa Y,Yang HC,Tian H,Cheng L,Arimitsu T,Takahashi T,Tong Y

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVE:We recently developed soft neural interfaces enabling the delivery of electrical and chemical stimulation to the spinal cord. These stimulations restored locomotion in animal models of paralysis. Soft interfaces can be placed either below or above the dura mater. Theoretically, the subdural location combines ...

journal_title：Journal of neural engineering

authors： Capogrosso M,Gandar J,Greiner N,Moraud EM,Wenger N,Shkorbatova P,Musienko P,Minev I,Lacour S,Courtine G

更新日期：2018-04-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to compare the use of muscles appropriate for partial-hand prostheses with those typically used for complete hand devices and to determine whether differences in their underlying neural substrates translate to different levels of myoelectric control. APPROACH:We developed a no...

journal_title：Journal of neural engineering

authors： Dyson M,Barnes J,Nazarpour K

更新日期：2018-10-01 00:00:00

abstract：OBJECTIVE:To evaluate the potential of intracortical electrode array signals for brain-computer interfaces (BCIs) to restore lost speech, we measured the performance of decoders trained to discriminate a comprehensive basis set of 39 English phonemes and to synthesize speech sounds via a neural pattern matching method....

journal_title：Journal of neural engineering

authors： Wilson GH,Stavisky SD,Willett FR,Avansino DT,Kelemen JN,Hochberg LR,Henderson JM,Druckmann S,Shenoy KV

更新日期：2020-11-25 00:00:00

abstract：OBJECTIVE:Neuromodulation technologies are increasingly used for improving function after neural injury. To achieve a symbiotic relationship between device and user, the device must augment remaining function, and independently adapt to day-to-day changes in function. The goal of this study was to develop predictive co...

journal_title：Journal of neural engineering

authors： Dalrymple AN,Roszko DA,Sutton RS,Mushahwar VK

更新日期：2020-06-02 00:00:00

abstract：OBJECTIVE:Contemporary deep brain stimulation (DBS) for Parkinson's disease is delivered continuously, and adjustments based on patient's changing symptoms must be made manually by a trained clinician. Patients may be subjected to energy intensive settings at times when they are not needed, possibly resulting in stimul...

journal_title：Journal of neural engineering

authors： Swann NC,de Hemptinne C,Thompson MC,Miocinovic S,Miller AM,Gilron R,Ostrem JL,Chizeck HJ,Starr PA

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVE:The aim of this paper was to characterize brain non-stationarity during an auditory oddball task in schizophrenia (SCH). The level of non-stationarity was measured in the baseline and response windows of relevant tones in SCH patients and healthy controls. APPROACH:Event-related potentials were recorded from...

journal_title：Journal of neural engineering

authors： Núñez P,Poza J,Bachiller A,Gomez-Pilar J,Lubeiro A,Molina V,Hornero R

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVE:The past two decades have seen dramatic progress in our ability to model brain signals recorded by electroencephalography, functional near-infrared spectroscopy, etc., and to derive real-time estimates of user cognitive state, response, or intent for a variety of purposes: to restore communication by the seve...

journal_title：Journal of neural engineering

authors： Kothe CA,Makeig S

更新日期：2013-10-01 00:00:00

abstract：OBJECTIVE:Depression is a severe mental disorder. However, the neural mechanisms underlying affective interference (difficulties in directing attention away from negative distractors) in depression patients are still not well-understood. In particular, the connections between brain regions remain unclear. Using the emo...

journal_title：Journal of neural engineering

authors： Guo Z,Wu X,Liu J,Yao L,Hu B

更新日期：2018-10-01 00:00:00

abstract：OBJECTIVE:We consider the problem of optimal probing to learn connections in an evoked dynamic network. Such a network, in which each edge measures an input-output relationship between sites in sensor/actuator-space, is relevant to emerging applications in neural mapping and neural connectivity estimation. APPROACH:We...

journal_title：Journal of neural engineering

authors： Kafashan M,Ching S

更新日期：2015-12-01 00:00:00

abstract：OBJECTIVE:For intracortical brain-machine interfaces (BMIs), action potential voltage waveforms are often sorted to separate out individual neurons. If these neurons contain independent tuning information, this process could increase BMI performance. However, the sorting of action potentials ('spikes') requires high sa...

journal_title：Journal of neural engineering

authors： Christie BP,Tat DM,Irwin ZT,Gilja V,Nuyujukian P,Foster JD,Ryu SI,Shenoy KV,Thompson DE,Chestek CA

更新日期：2015-02-01 00:00:00

abstract：OBJECTIVE:Real-time closed-loop neural feedback control requires the analysis of action potential traces within several milliseconds after they have been recorded from the brain. The current generation of spike clustering algorithms were mostly designed for off-line use and also require a significant amount of computat...

journal_title：Journal of neural engineering

authors： Mohammadi Z,Kincaid JM,Pun SH,Klug A,Liu C,Lei TC

更新日期：2019-07-30 00:00:00

abstract：:The peripheral nerves of an amputee's residual limb still carry the information required to provide the robust, natural control signals needed to command a dexterous prosthetic limb. However, these signals are mixed in the volume conductor of the body and extracting them is an unmet challenge. A beamforming algorithm ...

journal_title：Journal of neural engineering

authors： Wodlinger B,Durand DM

更新日期：2011-10-01 00:00:00

abstract：:To properly observe induced connectivity changes after training sessions, one needs a network model that describes individual relationships in sufficient detail to enable observation of induced changes and yet reveals some kind of stability in these relationships. We analyzed spontaneous firing activity in dissociated...

journal_title：Journal of neural engineering

authors： le Feber J,Rutten WL,Stegenga J,Wolters PS,Ramakers GJ,van Pelt J

更新日期：2007-06-01 00:00:00

abstract：:Brain-computer interface (BCI) systems allow people with severe motor disabilities to communicate and interact with the external world. The P300 potential is one of the most used control signals for EEG-based BCIs. Classic P300-based BCIs work in a synchronous mode; the synchronous control assumes that the user is con...

journal_title：Journal of neural engineering

authors： Aloise F,Schettini F,Aricò P,Leotta F,Salinari S,Mattia D,Babiloni F,Cincotti F

更新日期：2011-04-01 00:00:00

abstract：:In this paper, we investigate the influence of hypercapnia on the dynamics of the phrenic neurogram in the piglet in two different age groups: 3-7 days (n = 11) and 10-16 days (n = 9). The phrenic neurogram was recorded from 17 piglets (3-16 days old) during control (40% O(2) with 3-5% end-tidal CO(2)), mild hypercapn...

journal_title：Journal of neural engineering

authors： Akay M

更新日期：2005-06-01 00:00:00

abstract：OBJECTIVE:We implemented computational models of human and rat cortical neurons for simulating the neural response to cortical stimulation with electromagnetic fields. APPROACH:We adapted model neurons from the library of Blue Brain models to reflect biophysical and geometric properties of both adult rat and human cor...

journal_title：Journal of neural engineering

authors： Aberra AS,Peterchev AV,Grill WM

更新日期：2018-12-01 00:00:00

abstract：:Functional mapping of eloquent cortex is a common and necessary component of neurosurgical operative planning. Current electrical stimulation-based techniques are inefficient, can evoke seizures and are prone to false-negative results. Here, we present a novel cortical mapping system that extracts event-related neural...

journal_title：Journal of neural engineering

authors： Cheung C,Chang EF

更新日期：2012-08-01 00:00:00

abstract：OBJECTIVE:Patients with amyotrophic lateral sclerosis (ALS) may benefit from brain-computer interfaces (BCI), but the utility of such devices likely will have to account for the functional, cognitive, and behavioral heterogeneity of this neurodegenerative disorder. APPROACH:In this study, a heterogeneous group of pati...

journal_title：Journal of neural engineering

authors： Geronimo A,Simmons Z,Schiff SJ

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVE:Brain-computer interfaces (BCIs) have the potential to be valuable clinical tools. However, the varied nature of BCIs, combined with the large number of laboratories participating in BCI research, makes uniform performance reporting difficult. To address this situation, we present a tutorial on performance me...

journal_title：Journal of neural engineering

authors： Thompson DE,Quitadamo LR,Mainardi L,Laghari KU,Gao S,Kindermans PJ,Simeral JD,Fazel-Rezai R,Matteucci M,Falk TH,Bianchi L,Chestek CA,Huggins JE

更新日期：2014-06-01 00:00:00

abstract：:In this work, we proposed a novel architecture for real-time quantitative characterization of functional brain connectivity networks derived from Electroencephalogram (EEG). It consists of two main parts - calculation of Phase Lag Index (PLI) to form the functional connectivity networks and the extraction of a set of ...

journal_title：Journal of neural engineering

authors： Gutierrez Nuno RA,Chung CHR,Maharatna K

更新日期：2020-12-16 00:00:00