Abstract:
:In this work, we proposed a novel architecture for real-time quantitative characterization of functional brain connectivity networks derived from Electroencephalogram (EEG). It consists of two main parts - calculation of Phase Lag Index (PLI) to form the functional connectivity networks and the extraction of a set of graph-theoretic parameters to quantitatively characterize these networks. The architecture was developed for a 19-channel EEG system. The system can calculate all the functional connectivity parameters in a total time of 131µs, utilizes 71% logic resources, and shows 51.84 mW dynamic power consumption at 22.16 MHz operation frequency when implemented in a Stratix IV EP4SGX230K FPGA. Our analysis also showed that the system occupies an area equivalent to approximately 937K 2-input NAND gates, with an estimated power consumption of 39.3 mW at 0.9 V supply using a 90 nm CMOS Application Specific Integrated Circuit (ASIC) technology.
journal_name
J Neural Engjournal_title
Journal of neural engineeringauthors
Gutierrez Nuno RA,Chung CHR,Maharatna Kdoi
10.1088/1741-2552/abd462subject
Has Abstractpub_date
2020-12-16 00:00:00eissn
1741-2560issn
1741-2552pub_type
杂志文章abstract:OBJECTIVE:The Subthalamic Nucleus (STN) is the most selected target for the placement of the Deep Brain Stimulation (DBS) electrode to treat Parkinson's disease. Its identification is a delicate and challenging task which is based on the interpretation of the STN functional activity acquired through microelectrode reco...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2552/abcb15
更新日期:2020-11-17 00:00:00
abstract:OBJECTIVE:The use of natural sounds in auditory Brain-Computer Interfaces (BCI) has been shown to improve classification results and usability. Some auditory BCIs are based on stream segregation, in which the subjects must attend one audio stream and ignore the other(s); these streams include some kind of stimuli to be...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2552/abdd44
更新日期:2021-01-19 00:00:00
abstract:OBJECTIVE:Analysis of intra- and perioperatively recorded cortical and basal ganglia local field potentials in human movement disorders has provided great insight into the pathophysiology of diseases such as Parkinson's, dystonia, and essential tremor. However, in order to better understand the network abnormalities an...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/11/1/016009
更新日期:2014-02-01 00:00:00
abstract::Current treatment concepts for epilepsy are based on continuous drug delivery or electrical stimulation to prevent the occurrence of seizures, exposing the brain and body to a mostly unneeded risk of adverse effects. To address the infrequent occurrence and short duration of epileptic seizures, intelligent implantable...
journal_title:Journal of neural engineering
pub_type: 杂志文章,评审
doi:10.1088/1741-2552/ab094a
更新日期:2019-08-01 00:00:00
abstract:OBJECTIVE:To determine whether the estimated fraction and degree of distribution of visual responsive neurons in human intracranial microwire recordings depends upon the spike sorting method used. APPROACH:A large dataset of human intracranial microwire recordings from four brain areas was sorted into single unit acti...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2552/ab6cb8
更新日期:2020-04-09 00:00:00
abstract:OBJECTIVE:Given current clinical interest in vagus nerve stimulation (VNS), there are surprisingly few studies characterizing the anatomy of the vagus nerve in large animal models as it pertains to on-and off-target engagement of local fibers. We sought to address this gap by evaluating vagal anatomy in the pig, whose ...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2552/ab7ad4
更新日期:2020-04-09 00:00:00
abstract::Repositioning microelectrodes post-implantation is emerging as a promising approach to achieve long-term reliability in single neuronal recordings. The main goal of this study was to (a) assess glial reaction in response to movement of microelectrodes in the brain post-implantation and (b) determine an optimal window ...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/6/4/046004
更新日期:2009-08-01 00:00:00
abstract:OBJECTIVE:Due to their increased proximity to retinal ganglion cells (RGCs), epiretinal visual prostheses present the opportunity for eliciting phosphenes with low thresholds through direct RGC activation. This study characterised the in vivo performance of a novel prototype monolithic epiretinal prosthesis, containing...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2552/aba560
更新日期:2020-08-05 00:00:00
abstract:OBJECTIVE:Microwire and Utah-style neural recording arrays are the predominant devices used for cortical neural recording, but the implanted electrodes cause a significant adverse biological response and suffer from well-studied performance degradation. Recent work has demonstrated that carbon fiber electrodes do not e...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2552/aae8d9
更新日期:2019-02-01 00:00:00
abstract:OBJECTIVE:Brain-computer interfaces (BCI) are becoming important tools for assistive technology, particularly through the use of motor imagery (MI) for aiding task completion. However, most existing methods of MI classification have been applied in a trial-wise fashion, with window sizes of approximately 2 s or more. A...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2552/ab57c0
更新日期:2020-01-31 00:00:00
abstract::This comment constitutes a re-assessment of a recent study in which near-infrared spectroscopy (NIRS) was used to decode decision making. In the original study, the process of feature selection was carried out on all of the data, and those features which displayed the greater classification accuracy were selected, but...
journal_title:Journal of neural engineering
pub_type: 评论,杂志文章
doi:10.1088/1741-2560/6/5/058001
更新日期:2009-10-01 00:00:00
abstract:OBJECTIVE:Functions ascribed to the hippocampal sub-regions for encoding episodic memories include the separation of activity patterns propagated from the entorhinal cortex (EC) into the dentate gyrus (DG) and pattern completion in CA3 region. Since a direct assessment of these functions is lacking at the level of spec...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2552/aabc20
更新日期:2018-08-01 00:00:00
abstract:OBJECTIVE:To evaluate the potential of intracortical electrode array signals for brain-computer interfaces (BCIs) to restore lost speech, we measured the performance of decoders trained to discriminate a comprehensive basis set of 39 English phonemes and to synthesize speech sounds via a neural pattern matching method....
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2552/abbfef
更新日期:2020-11-25 00:00:00
abstract:OBJECTIVE:The objective of this study was to compare the use of muscles appropriate for partial-hand prostheses with those typically used for complete hand devices and to determine whether differences in their underlying neural substrates translate to different levels of myoelectric control. APPROACH:We developed a no...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2552/aacbfe
更新日期:2018-10-01 00:00:00
abstract:OBJECTIVE:Patients with amyotrophic lateral sclerosis (ALS) may benefit from brain-computer interfaces (BCI), but the utility of such devices likely will have to account for the functional, cognitive, and behavioral heterogeneity of this neurodegenerative disorder. APPROACH:In this study, a heterogeneous group of pati...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/13/2/026002
更新日期:2016-04-01 00:00:00
abstract:OBJECTIVE:While motor-imagery based brain-computer interfaces (BCIs) have been studied over many years by now, most of these studies have taken place in controlled lab settings. Bringing BCI technology into everyday life is still one of the main challenges in this field of research. APPROACH:This paper systematically ...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/13/5/056012
更新日期:2016-10-01 00:00:00
abstract::We introduce algorithms and architectures for automatic spike detection and alignment that are designed for low power. Some of the algorithms are based on principal component analysis (PCA). Others employ a novel integral transform analysis and achieve 99% of the precision of a PCA detector, while requiring only 0.05%...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/3/1/004
更新日期:2006-03-01 00:00:00
abstract::The aim of this study was to assess the accuracy of the convolution kernel compensation (CKC) method in decomposing high-density surface EMG (HDsEMG) signals from the pennate biceps femoris long-head muscle. Although the CKC method has already been thoroughly assessed in parallel-fibered muscles, there are several fac...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/8/6/066002
更新日期:2011-12-01 00:00:00
abstract::Implantable electrode arrays capable of recording and stimulating neural activity with high spatial and temporal resolution will provide a foundation for future brain computer interface technology. Currently, their clinical impact has been curtailed by a general lack of functional stability, which can be attributed to...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/5/4/003
更新日期:2008-12-01 00:00:00
abstract::We consider the problem of desynchronizing a network of synchronized, globally (all-to-all) coupled neurons using an input to a single neuron. This is done by applying the discrete time dynamic programming method to reduced phase models for neural populations. This technique numerically minimizes a certain cost functi...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/8/6/065008
更新日期:2011-12-01 00:00:00
abstract:OBJECTIVE:Dry electrodes have an advantage over gel-based 'wet' electrodes by providing quicker set-up time for electroencephalography recording; however, the potentially poorer contact can result in noisier recordings. We examine the impact that this may have on brain-computer interface communication and potential app...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/13/6/066018
更新日期:2016-12-01 00:00:00
abstract:OBJECTIVE:Stability and selectivity are important when restoring long-term, functional sensory feedback in individuals with limb-loss. Our objective is to demonstrate a chronic, clinical neural stimulation system for providing selective sensory response in two upper-limb amputees. APPROACH:Multi-contact cuff electrode...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/12/2/026002
更新日期:2015-04-01 00:00:00
abstract:OBJECTIVE:Multimodal neuroimaging approaches are beneficial to discover brain functionalities at high spatial and temporal resolution. In our work, a novel material composition of a microECoG device relying on Parylene HT and indium-tin-oxide (ITO) is presented, which facilitates two-photon imaging of Ca2+ signals and ...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2552/ab603f
更新日期:2020-02-18 00:00:00
abstract::A motor imagery based brain-computer interface (BCI) provides a non-muscular communication channel that enables people with paralysis to control external devices using their motor imagination. Reducing the number of electrodes is critical to improving the portability and practicability of the BCI system. A novel metho...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/5/3/007
更新日期:2008-09-01 00:00:00
abstract:OBJECTIVE:In spite of intense theoretical and experimental investigations on electrical nerve stimulation, the influence of reversed ion currents on network activity during extracellular stimulation has not been investigated so far. APPROACH:Here, the impact of calcium current reversal on neurotransmitter release duri...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/13/4/046013
更新日期:2016-08-01 00:00:00
abstract:OBJECTIVE:Medical implants made of non-biological materials provoke a chronic inflammatory response, resulting in the deposition of a collagenous scar tissue (ST) layer on their surface, that gradually thickens over time. This is a critical problem for neural interfaces. Scar build-up on electrodes results in a progres...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/13/2/026006
更新日期:2016-04-01 00:00:00
abstract:OBJECTIVE:Most recent steady-state visual evoked potential (SSVEP)-based brain-computer interface (BCI) systems have used a single frequency for each target, so that a large number of targets require a large number of stimulus frequencies and therefore a wider frequency band. However, human beings show good SSVEP respo...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/10/6/066009
更新日期:2013-12-01 00:00:00
abstract::Automatic spike sorting is a prerequisite for neuroscience research on multichannel extracellular recordings of neuronal activity. A novel spike sorting framework, combining efficient feature extraction and an unsupervised clustering method, is described here. Wavelet transform (WT) is adopted to extract features from...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/8/3/036003
更新日期:2011-06-01 00:00:00
abstract:OBJECTIVE:Activity-dependent stimulation (ADS) is designed to strengthen the connections between neuronal circuits and therefore may be a promising tool for promoting neurophysiological reorganization following a brain injury. To successfully perform this technique, two criteria must be met: (1) spikes in the extracell...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2552/ab3319
更新日期:2019-10-29 00:00:00
abstract:OBJECTIVE:Reliable chronic recordings from implanted neural probes remain a significant challenge; current silicon-based and microwire technologies experience a wide range of biotic and abiotic failure modes contributing to loss of signal quality. APPROACH:A multi-prong alternative strategy with potential to overcome ...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/10/4/045002
更新日期:2013-08-01 00:00:00