On the risk of extracting relevant information from random data.

abstract：OBJECTIVE:Sleep spindles in the electroencephalogram (EEG) are significant in sleep analysis related to cognitive functions and neurological diseases, and thus are of great clinical interests. An automatic sleep spindle detection algorithm could help decrease the workload of visual inspection by sleep clinicians. APPR...

journal_title：Journal of neural engineering

authors： Jiang D,Ma Y,Wang Y

更新日期：2020-12-16 00:00:00

abstract：:Chronic motor cortex stimulation (MCS) is currently being investigated as a treatment method for Parkinson's disease (PD). Unfortunately, the underlying mechanisms of this treatment are unclear and there are many uncertainties regarding the most effective stimulation parameters and electrode configuration. In this pap...

journal_title：Journal of neural engineering

authors： Zwartjes DG,Heida T,Feirabend HK,Janssen ML,Visser-Vandewalle V,Martens HC,Veltink PH

更新日期：2012-10-01 00:00:00

abstract：:Significant progress has been made in systems that interpret the electrical signals of the brain in order to control an actuator. One version of these systems senses neuronal extracellular action potentials with an array of up to 100 miniature probes inserted into the cortex. The impedance of each probe is high, so en...

journal_title：Journal of neural engineering

authors： Jochum T,Denison T,Wolf P

更新日期：2009-02-01 00:00:00

abstract：:One of the most important stages in a brain-computer interface (BCI) system is that of extracting features that can reliably discriminate data recorded during different user states. A popular technique used for feature extraction in BCIs is the common spatial patterns (CSP) method, which provides a set of spatial filt...

journal_title：Journal of neural engineering

authors： Falzon O,Camilleri KP,Muscat J

更新日期：2012-08-01 00:00:00

abstract：:Functional electrical stimulation (FES) involves artificial activation of muscles with surface or implanted electrodes to restore motor function in paralyzed individuals. Currently, FES-based prostheses produce only a limited range of movements due to the difficulty associated with identifying patterns of muscle activ...

journal_title：Journal of neural engineering

authors： Johnson LA,Fuglevand AJ

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVE:Electroencephalography (EEG) offers a unique opportunity to study human neural activity non-invasively with millisecond resolution using minimal equipment in or outside of a lab setting. EEG can be combined with a number of techniques for closed-loop experiments, where external devices are driven by specific ...

journal_title：Journal of neural engineering

authors： Black C,Voigts J,Agrawal U,Ladow M,Santoyo J,Moore C,Jones S

更新日期：2017-06-01 00:00:00

abstract：OBJECTIVE:The fact that all human action is preceded by brain processes partially observable through neuroimaging devices such as electroencephalography (EEG) is currently being explored in a number of applications. A recent study by Haufe et al (2011 J. Neural Eng. 8 056001) demonstrates the possibility of performing ...

journal_title：Journal of neural engineering

authors： Haufe S,Kim JW,Kim IH,Sonnleitner A,Schrauf M,Curio G,Blankertz B

更新日期：2014-10-01 00:00:00

abstract：:Electrical stimulation of peripheral nerve activates large-diameter fibers before small ones. A physiological recruitment order, from small to large-diameter axons, is desirable in many applications. Previous studies using computer simulations showed that selective activation of small fibers could be achieved by resha...

journal_title：Journal of neural engineering

authors： Lertmanorat Z,Durand DM

更新日期：2004-12-01 00:00:00

abstract：OBJECTIVE:Patients with amyotrophic lateral sclerosis (ALS) may benefit from brain-computer interfaces (BCI), but the utility of such devices likely will have to account for the functional, cognitive, and behavioral heterogeneity of this neurodegenerative disorder. APPROACH:In this study, a heterogeneous group of pati...

journal_title：Journal of neural engineering

authors： Geronimo A,Simmons Z,Schiff SJ

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVE:Stability and selectivity are important when restoring long-term, functional sensory feedback in individuals with limb-loss. Our objective is to demonstrate a chronic, clinical neural stimulation system for providing selective sensory response in two upper-limb amputees. APPROACH:Multi-contact cuff electrode...

journal_title：Journal of neural engineering

authors： Tan DW,Schiefer MA,Keith MW,Anderson JR,Tyler DJ

更新日期：2015-04-01 00:00:00

abstract：OBJECTIVE:Medical implants made of non-biological materials provoke a chronic inflammatory response, resulting in the deposition of a collagenous scar tissue (ST) layer on their surface, that gradually thickens over time. This is a critical problem for neural interfaces. Scar build-up on electrodes results in a progres...

journal_title：Journal of neural engineering

authors： FitzGerald JJ

更新日期：2016-04-01 00:00:00

abstract：:In this paper, we propose a simple and straightforward algorithm for neural spike sorting. The algorithm is based on the observation that the distribution of a neural signal largely deviates from the uniform distribution and is rather unimodal. The detected spikes to be sorted are first processed with some feature ext...

journal_title：Journal of neural engineering

authors： Tiganj Z,Mboup M

更新日期：2011-12-01 00:00:00

abstract：OBJECTIVE:Neural reflexes regulate immune responses and homeostasis. Advances in bioelectronic medicine indicate that electrical stimulation of the vagus nerve can be used to treat inflammatory disease, yet the understanding of neural signals that regulate inflammation is incomplete. Current interfaces with the vagus n...

journal_title：Journal of neural engineering

authors： Caravaca AS,Tsaava T,Goldman L,Silverman H,Riggott G,Chavan SS,Bouton C,Tracey KJ,Desimone R,Boyden ES,Sohal HS,Olofsson PS

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVE:It is known that multi-site interleaved stimulation generates less muscle fatigue compared to single-site synchronous stimulation. However, in the limited number of studies in which intramuscular electrodes were used, the fatigue reduction associated with interleaved stimulation could not consistently be achi...

journal_title：Journal of neural engineering

authors： Eladly A,Del Valle J,Minguillon J,Mercadal B,Becerra-Fajardo L,Navarro X,Ivorra A

更新日期：2020-08-25 00:00:00

abstract：:The blood oxygenation level dependent (BOLD) contrast has been commonly used to detect fMRI signal. The majority of the BOLD signals are believed to arise from the venous and capillary networks. However, only those from the capillaries are spatially close to the neuronal activities, while the signals from large veins ...

journal_title：Journal of neural engineering

authors： Song AW,Gangstead SL

更新日期：2004-03-01 00:00:00

abstract：:Hybrid electro-optical neural stimulation is a novel paradigm combining the advantages of optical and electrical stimulation techniques while reducing their respective limitations. However, in order to fulfill its promise, this technique requires reduced variability and improved reproducibility. Here we used a compara...

journal_title：Journal of neural engineering

authors： Duke AR,Lu H,Jenkins MW,Chiel HJ,Jansen ED

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVE:Differential measurement of efferent and afferent peripheral nerve activity offers a promising means of improving the clinical utility of implantable neuroprostheses. The tripolar nerve cuff electrode has historically served as the gold standard for achieving high signal-to-noise ratios (SNRs) of the recordin...

journal_title：Journal of neural engineering

authors： Sabetian P,Popovic MR,Yoo PB

更新日期：2017-06-01 00:00:00

abstract：:We hypothesize that a visual prosthesis capable of evoking high-resolution visual perceptions can be produced using high-electrode-count arrays of penetrating microelectrodes implanted into the primary visual cortex of a blind human subject. To explore this hypothesis, and as a prelude to human psychophysical experime...

journal_title：Journal of neural engineering

authors： Torab K,Davis TS,Warren DJ,House PA,Normann RA,Greger B

更新日期：2011-06-01 00:00:00

abstract：OBJECTIVE:Neuromodulation technologies are increasingly used for improving function after neural injury. To achieve a symbiotic relationship between device and user, the device must augment remaining function, and independently adapt to day-to-day changes in function. The goal of this study was to develop predictive co...

journal_title：Journal of neural engineering

authors： Dalrymple AN,Roszko DA,Sutton RS,Mushahwar VK

更新日期：2020-06-02 00:00:00

abstract：:Repositioning microelectrodes post-implantation is emerging as a promising approach to achieve long-term reliability in single neuronal recordings. The main goal of this study was to (a) assess glial reaction in response to movement of microelectrodes in the brain post-implantation and (b) determine an optimal window ...

journal_title：Journal of neural engineering

authors： Stice P,Muthuswamy J

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVE:We have previously demonstrated a brain-machine interface neuroprosthetic system that provided continuous control of functional electrical stimulation (FES) and restoration of grasp in a primate model of spinal cord injury (SCI). Predicting intended EMG directly from cortical recordings provides a flexible hi...

journal_title：Journal of neural engineering

authors： Ethier C,Acuna D,Solla SA,Miller LE

更新日期：2016-08-01 00:00:00

abstract：:We present a micromachined 252-channel ECoG (electrocorticogram)-electrode array, which is made of a thin polyimide foil substrate enclosing sputtered platinum electrode sites and conductor paths. The array subtends an area of approximately 35 mm by 60 mm and is designed to cover large parts of a hemisphere of a macaq...

journal_title：Journal of neural engineering

authors： Rubehn B,Bosman C,Oostenveld R,Fries P,Stieglitz T

更新日期：2009-06-01 00:00:00

abstract：OBJECTIVE:Deep brain stimulation (DBS) of the internal segment of the globus pallidus (GPi) in patients with Parkinson's disease and dystonia improves motor symptoms and quality of life. Traditionally, pallidal borders have been demarcated by electrophysiological microelectrode recordings (MERs) during DBS surgery. How...

journal_title：Journal of neural engineering

authors： Valsky D,Blackwell KT,Tamir I,Eitan R,Bergman H,Israel Z

更新日期：2020-01-06 00:00:00

abstract：OBJECTIVE:While motor-imagery based brain-computer interfaces (BCIs) have been studied over many years by now, most of these studies have taken place in controlled lab settings. Bringing BCI technology into everyday life is still one of the main challenges in this field of research. APPROACH:This paper systematically ...

journal_title：Journal of neural engineering

authors： Brandl S,Frølich L,Höhne J,Müller KR,Samek W

更新日期：2016-10-01 00:00:00

abstract：OBJECTIVE:Haptic feedback is crucial when we manipulate objects. Information pertaining to an object's stiffness in particular can help facilitate fine motor control. In this study, we seek to determine whether objects of different stiffness levels can be recognized using haptic feedback provided by transcutaneous elec...

journal_title：Journal of neural engineering

authors： Vargas L,Shin H,Huang HH,Zhu Y,Hu X

更新日期：2019-12-05 00:00:00

abstract：OBJECTIVE:Brain-machine interfaces (BMIs) have been proposed in closed-loop applications for neuromodulation and neurorehabilitation. This study describes the impact of different feedback modalities on the performance of an EEG-based BMI that decodes motor imagery (MI) of leg flexion and extension. APPROACH:We execute...

journal_title：Journal of neural engineering

authors： Liu D,Chen W,Lee K,Chavarriaga R,Bouri M,Pei Z,Del R Millán J

更新日期：2017-10-01 00:00:00

abstract：OBJECTIVE:A primary control signal in brain-computer interfaces (BCIs) have been cortical signals related to movement. However, in cases where natural motor function remains, BCI control signals may interfere with other possibly simultaneous activity for useful ongoing movement. We sought to determine if the brain coul...

journal_title：Journal of neural engineering

authors： Bashford L,Wu J,Sarma D,Collins K,Rao RPN,Ojemann JG,Mehring C

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVE:The aim of this paper was to characterize brain non-stationarity during an auditory oddball task in schizophrenia (SCH). The level of non-stationarity was measured in the baseline and response windows of relevant tones in SCH patients and healthy controls. APPROACH:Event-related potentials were recorded from...

journal_title：Journal of neural engineering

authors： Núñez P,Poza J,Bachiller A,Gomez-Pilar J,Lubeiro A,Molina V,Hornero R

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVE:Intracranial EEG (iEEG) or micro-electrocorticography (µECoG) microelectrodes offer high spatial resolution in recordings of neuronal activity from the exposed brain surface. Reliability of dielectric substrates and conductive materials of these devices are under intensive research in terms of functional stab...

journal_title：Journal of neural engineering

authors： Zátonyi A,Fedor F,Borhegyi Z,Fekete Z

更新日期：2018-10-01 00:00:00

abstract：OBJECTIVE:State of the art brain-computer interface (BCI) research focuses on improving individual components such as the application or the decoder that converts the user's brain activity to control signals. In this study, we investigate the interaction between these components in the P300 speller, a BCI for communica...

journal_title：Journal of neural engineering

authors： Verhoeven T,Buteneers P,Wiersema JR,Dambre J,Kindermans PJ

更新日期：2015-12-01 00:00:00