Transparent, low-autofluorescence microECoG device for simultaneous Ca2+ imaging and cortical electrophysiology in vivo.

abstract：:Hybrid electro-optical neural stimulation is a novel paradigm combining the advantages of optical and electrical stimulation techniques while reducing their respective limitations. However, in order to fulfill its promise, this technique requires reduced variability and improved reproducibility. Here we used a compara...

journal_title：Journal of neural engineering

authors： Duke AR,Lu H,Jenkins MW,Chiel HJ,Jansen ED

更新日期：2012-06-01 00:00:00

abstract：:In this work, we proposed a novel architecture for real-time quantitative characterization of functional brain connectivity networks derived from Electroencephalogram (EEG). It consists of two main parts - calculation of Phase Lag Index (PLI) to form the functional connectivity networks and the extraction of a set of ...

journal_title：Journal of neural engineering

authors： Gutierrez Nuno RA,Chung CHR,Maharatna K

更新日期：2020-12-16 00:00:00

abstract：OBJECTIVE:We have recently developed a prototype of a novel human-computer interface for assistive communication based on voluntary shifts of attention (gaze) from a far target to a near target associated with a decrease of pupil size (Pupillary Accommodative Response, PAR), an automatic vegetative response that can be...

journal_title：Journal of neural engineering

authors： de'Sperati C,Roatta S,Zovetti N,Baroni T

更新日期：2020-04-29 00:00:00

abstract：:To study cell-field dynamics, physiologists simultaneously record local field potentials and the activity of individual cells from animals performing cognitive tasks, during various brain states or under pathological conditions. However, apart from spike shape and spike timing analyses, few studies have focused on elu...

journal_title：Journal of neural engineering

authors： Cotic M,Chiu AW,Jahromi SS,Carlen PL,Bardakjian BL

更新日期：2011-08-01 00:00:00

abstract：:Microscopic aggregation assay and impedance sensing (IS) were used to monitor a change in in vitro neuron-neuron adhesion in response to blocking of cell adhesion molecules. By blocking neuron-neuron adhesion, migration and aggregation of neuronal cells can be inhibited. This leads to better control of spatial arrange...

journal_title：Journal of neural engineering

authors： Wiertz RW,Marani E,Rutten WL

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVE:Recent advances in neural engineering have restored mobility to people with paralysis, relieved symptoms of movement disorders, reduced chronic pain, restored the sense of hearing, and provided sensory perception to individuals with sensory deficits. APPROACH:This progress was enabled by the team-based, inte...

journal_title：Journal of neural engineering

authors： Ereifej ES,Shell CE,Schofield JS,Charkhkar H,Cuberovic I,Dorval AD,Graczyk EL,Kozai TDY,Otto KJ,Tyler DJ,Welle CG,Widge AS,Zariffa J,Moritz CT,Bourbeau DJ,Marasco PD

更新日期：2019-11-12 00:00:00

abstract：OBJECTIVE:Reliable chronic recordings from implanted neural probes remain a significant challenge; current silicon-based and microwire technologies experience a wide range of biotic and abiotic failure modes contributing to loss of signal quality. APPROACH:A multi-prong alternative strategy with potential to overcome ...

journal_title：Journal of neural engineering

authors： Kim BJ,Kuo JT,Hara SA,Lee CD,Yu L,Gutierrez CA,Hoang TQ,Pikov V,Meng E

更新日期：2013-08-01 00:00:00

abstract：OBJECTIVE:Penetrating cortical neural probe technologies allow investigators to record electrical signals in the brain. Implantation of probes results in acute tissue damage, and microglia density increases around implanted devices over weeks. However, the mechanisms underlying this encapsulation are not well understoo...

journal_title：Journal of neural engineering

authors： Kozai TD,Vazquez AL,Weaver CL,Kim SG,Cui XT

更新日期：2012-12-01 00:00:00

abstract：:Current treatment concepts for epilepsy are based on continuous drug delivery or electrical stimulation to prevent the occurrence of seizures, exposing the brain and body to a mostly unneeded risk of adverse effects. To address the infrequent occurrence and short duration of epileptic seizures, intelligent implantable...

journal_title：Journal of neural engineering

authors： Dümpelmann M

更新日期：2019-08-01 00:00:00

abstract：OBJECTIVES:We aimed to develop a robotic interface capable of providing finely-tuned, multidirectional trunk assistance adjusted in real-time during unconstrained locomotion in rats and mice. APPROACH:We interfaced a large-scale robotic structure actuated in four degrees of freedom to exchangeable attachment modules e...

journal_title：Journal of neural engineering

authors： von Zitzewitz J,Asboth L,Fumeaux N,Hasse A,Baud L,Vallery H,Courtine G

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVE:Implantable brain-computer interface (BCI) research promises improvements in human health and enhancements in quality of life. Informed consent of subjects is a central tenet of this research. Rapid advances in neuroscience, and the intimate connection between functioning of the brain and conceptions of the s...

journal_title：Journal of neural engineering

authors： Klein E,Ojemann J

更新日期：2016-08-01 00:00:00

abstract：OBJECTIVE:The goal of this study is to characterize the phenomenon of evoked tactile sensation (ETS) on the stump skin of forearm amputees using transcutaneous electrical nerve stimulation (TENS). APPROACH:We identified the projected finger map (PFM) of ETS on the stump skin in 11 forearm amputees, and compared percep...

journal_title：Journal of neural engineering

authors： Chai G,Sui X,Li S,He L,Lan N

更新日期：2015-12-01 00:00:00

abstract：:We describe a brain-computer interface for controlling a humanoid robot directly using brain signals obtained non-invasively from the scalp through electroencephalography (EEG). EEG has previously been used for tasks such as controlling a cursor and spelling a word, but it has been regarded as an unlikely candidate fo...

journal_title：Journal of neural engineering

authors： Bell CJ,Shenoy P,Chalodhorn R,Rao RP

更新日期：2008-06-01 00:00:00

abstract：OBJECTIVE:Somatic symptom disorder (SSD) is a reflection of medically unexplained physical symptoms that lead to distress and impairment in social and occupational functioning. SSD is phenomenologically diagnosed and its neurobiology remains unsolved. APPROACH:In this study, we performed hyper-parameter optimized clas...

journal_title：Journal of neural engineering

authors： Eken A,Çolak B,Bal NB,Kuşman A,Kızılpınar SÇ,Akaslan DS,Baskak B

更新日期：2019-12-16 00:00:00

abstract：:Spastic hypertonus (muscle over-activity due to exaggerated stretch reflexes) often develops in people with stroke, cerebral palsy, multiple sclerosis and spinal cord injury. Lesioning of nerves, e.g. with phenol or botulinum toxin is widely performed to reduce spastic hypertonus. We have explored the use of direct el...

journal_title：Journal of neural engineering

authors： Ravid EN,Gan LS,Todd K,Prochazka A

更新日期：2011-02-01 00:00:00

abstract：OBJECTIVE:Currently commercially available nerve conduits have demonstrated suboptimal clinical efficacy in repairing peripheral nerve defects. Although tissue-engineered nerve grafts (TENGs) with sustained release of neurotrophic factors (NTFs) are experimentally proved to be more effective than these blank conduits, ...

journal_title：Journal of neural engineering

authors： Liu Y,Yu S,Gu X,Cao R,Cui S

更新日期：2020-12-09 00:00:00

abstract：:In this paper, we investigate the influence of hypercapnia on the dynamics of the phrenic neurogram in the piglet in two different age groups: 3-7 days (n = 11) and 10-16 days (n = 9). The phrenic neurogram was recorded from 17 piglets (3-16 days old) during control (40% O(2) with 3-5% end-tidal CO(2)), mild hypercapn...

journal_title：Journal of neural engineering

authors： Akay M

更新日期：2005-06-01 00:00:00

abstract：:Implantable electrode arrays capable of recording and stimulating neural activity with high spatial and temporal resolution will provide a foundation for future brain computer interface technology. Currently, their clinical impact has been curtailed by a general lack of functional stability, which can be attributed to...

journal_title：Journal of neural engineering

authors： Retterer ST,Smith KL,Bjornsson CS,Turner JN,Isaacson MS,Shain W

更新日期：2008-12-01 00:00:00

abstract：OBJECTIVE:Cochlear implants, while providing significant benefits to recipients, remain limited due to broad neural activation. Focussed multipolar stimulation (FMP) is an advanced stimulation strategy that uses multiple current sources to produce highly focussed patterns of neural excitation in order to overcome these...

journal_title：Journal of neural engineering

authors： Senn P,Shepherd RK,Fallon JB

更新日期：2018-10-01 00:00:00

abstract：OBJECTIVE:The rapidly developing paradigm of closed-loop neuroscience has extensively employed brain rhythms as the signal forming real-time neurofeedback, triggering brain stimulation, or governing stimulus selection. However, the efficacy of brain rhythm contingent paradigms suffers from significant delays related to...

journal_title：Journal of neural engineering

authors： Smetanin N,Belinskaya A,Lebedev M,Ossadtchi A

更新日期：2020-08-04 00:00:00

abstract：OBJECTIVE:Currently, there are some 95 000 people in Europe suffering from upper-limb impairment. Rehabilitation should be undertaken right after the impairment occurs and should be regularly performed thereafter. Moreover, the rehabilitation process should be tailored specifically to both patient and impairment. APPR...

journal_title：Journal of neural engineering

authors： Nissler C,Nowak M,Connan M,Büttner S,Vogel J,Kossyk I,Márton ZC,Castellini C

更新日期：2019-04-01 00:00:00

abstract：OBJECTIVE:When developing approaches for automatic preprocessing of electroencephalogram (EEG) signals in non-isolated demanding environment such as intensive care unit (ICU) or even outdoor environment, one of the major concerns is varying nature of characteristics of different artifacts in time, frequency and spatial...

journal_title：Journal of neural engineering

authors： Bahador N,Erikson K,Laurila J,Koskenkari J,Ala-Kokko T,Kortelainen J

更新日期：2020-10-15 00:00:00

abstract：:The blood oxygenation level dependent (BOLD) contrast has been commonly used to detect fMRI signal. The majority of the BOLD signals are believed to arise from the venous and capillary networks. However, only those from the capillaries are spatially close to the neuronal activities, while the signals from large veins ...

journal_title：Journal of neural engineering

authors： Song AW,Gangstead SL

更新日期：2004-03-01 00:00:00

abstract：OBJECTIVE:Brain-computer interfaces (BCIs) can help patients who have lost control over most muscles but are still conscious and able to communicate or interact with the environment. One of the most popular types of BCI is the P300-based BCI. With this BCI, users are asked to count the number of appearances of target s...

journal_title：Journal of neural engineering

authors： Jin J,Zhang H,Daly I,Wang X,Cichocki A

更新日期：2017-06-01 00:00:00

abstract：OBJECTIVE:For intracortical brain-machine interfaces (BMIs), action potential voltage waveforms are often sorted to separate out individual neurons. If these neurons contain independent tuning information, this process could increase BMI performance. However, the sorting of action potentials ('spikes') requires high sa...

journal_title：Journal of neural engineering

authors： Christie BP,Tat DM,Irwin ZT,Gilja V,Nuyujukian P,Foster JD,Ryu SI,Shenoy KV,Thompson DE,Chestek CA

更新日期：2015-02-01 00:00:00

abstract：OBJECTIVE:Brain-computer interfaces (BCIs) have the potential to be valuable clinical tools. However, the varied nature of BCIs, combined with the large number of laboratories participating in BCI research, makes uniform performance reporting difficult. To address this situation, we present a tutorial on performance me...

journal_title：Journal of neural engineering

authors： Thompson DE,Quitadamo LR,Mainardi L,Laghari KU,Gao S,Kindermans PJ,Simeral JD,Fazel-Rezai R,Matteucci M,Falk TH,Bianchi L,Chestek CA,Huggins JE

更新日期：2014-06-01 00:00:00

abstract：OBJECTIVE:The advancement of surface electromyogram (sEMG) recording and signal processing techniques has allowed us to characterize the recruitment properties of a substantial population of motor units (MUs) non-invasively. Here we seek to determine whether MU recruitment properties are modified in paretic muscles of ...

journal_title：Journal of neural engineering

authors： Hu X,Suresh AK,Rymer WZ,Suresh NL

更新日期：2015-12-01 00:00:00

abstract：OBJECTIVE:Brain-machine interfaces (BMIs) have been proposed in closed-loop applications for neuromodulation and neurorehabilitation. This study describes the impact of different feedback modalities on the performance of an EEG-based BMI that decodes motor imagery (MI) of leg flexion and extension. APPROACH:We execute...

journal_title：Journal of neural engineering

authors： Liu D,Chen W,Lee K,Chavarriaga R,Bouri M,Pei Z,Del R Millán J

更新日期：2017-10-01 00:00:00

abstract：OBJECTIVE:The fact that all human action is preceded by brain processes partially observable through neuroimaging devices such as electroencephalography (EEG) is currently being explored in a number of applications. A recent study by Haufe et al (2011 J. Neural Eng. 8 056001) demonstrates the possibility of performing ...

journal_title：Journal of neural engineering

authors： Haufe S,Kim JW,Kim IH,Sonnleitner A,Schrauf M,Curio G,Blankertz B

更新日期：2014-10-01 00:00:00

abstract：OBJECTIVE:Spinal cord stimulation (SCS) is a common neurostimulation therapy to treat chronic pain. Computational models represent a valuable tool to study the potential mechanisms of action of SCS and to optimize the design and implementation of SCS technologies. However, it is imperative that these computational mode...

journal_title：Journal of neural engineering

authors： Zander HJ,Graham RD,Anaya CJ,Lempka SF

更新日期：2020-06-12 00:00:00